ATE148105T1 - Succinoylaminohydroxyäthylaminosulfamidsäureder vate und ihre verwendung als retrovirale proteasehemmer - Google Patents

Succinoylaminohydroxyäthylaminosulfamidsäureder vate und ihre verwendung als retrovirale proteasehemmer

Info

Publication number: ATE148105T1
Authority: AT; Austria
Prior art keywords: succinoylaminohydroxyethylaminosulfamic; vates; acid; protease inhibitors; retroviral protease
Prior art date: 1992-10-30

Application number

AT94901230T

Other languages

English (en)

Inventor

Michael L Vazquez

Richard A Mueller

John J Talley

Daniel P Getman

Crescenzo Gary A De

Eric T Sun

Original Assignee

Searle & Co

Monsanto Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-10-30

Filing date

1993-10-29

Publication date

1997-02-15

1993-10-29 Application filed by Searle & Co, Monsanto Co filed Critical Searle & Co

1997-02-15 Application granted granted Critical

1997-02-15 Publication of ATE148105T1 publication Critical patent/ATE148105T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/26—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C307/04—Diamides of sulfuric acids
- C07C307/06—Diamides of sulfuric acids having nitrogen atoms of the sulfamide groups bound to acyclic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT94901230T 1992-10-30 1993-10-29 Succinoylaminohydroxyäthylaminosulfamidsäureder vate und ihre verwendung als retrovirale proteasehemmer ATE148105T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US96968392A	1992-10-30	1992-10-30

Publications (1)

Publication Number	Publication Date
ATE148105T1 true ATE148105T1 (de)	1997-02-15

Family

ID=25515855

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94901230T ATE148105T1 (de)	1992-10-30	1993-10-29	Succinoylaminohydroxyäthylaminosulfamidsäureder vate und ihre verwendung als retrovirale proteasehemmer

Country Status (9)

Country	Link
EP (1)	EP0666841B1 (de)
AT (1)	ATE148105T1 (de)
AU (1)	AU5589294A (de)
CA (1)	CA2141570A1 (de)
DE (1)	DE69307726T2 (de)
DK (1)	DK0666841T3 (de)
ES (1)	ES2097023T3 (de)
GR (1)	GR3023044T3 (de)
WO (1)	WO1994010133A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5776971A (en)	1995-03-10	1998-07-07	G.D. Searle & Co.	Heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors
CN1149223C (zh) *	1995-03-10	2004-05-12	G·D·瑟尔公司	杂环羰基氨基酸羟乙氨基磺酰胺逆转录病毒蛋白酶抑制剂
US6407134B1 (en)	1995-03-10	2002-06-18	G. D. Searle & Co.	Heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors
DE19703713A1 (de) *	1997-01-23	1998-07-30	Hans Prof Dr Schick	Verfahren für die Herstellung von Oxetan-2-onen und Zwischenprodukte
US9855230B2 (en)	2014-09-09	2018-01-02	VIIV Healthcare UK (No.5) Limited	Inhibitors of human immunodeficiency virus replication

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL8800100A (nl) *	1987-01-21	1988-08-16	Sandoz Ag	Nieuwe peptidederivaten en werkwijzen voor het bereiden en toepassen van deze derivaten.
DE3830825A1 (de) *	1987-09-15	1989-03-23	Sandoz Ag	Hydrophile reninhemmer, ihre herstellung und verwendung
AU662114B2 (en) *	1990-11-19	1995-08-24	Monsanto Company	Retroviral protease inhibitors
CA2096525C (en) *	1990-11-19	2005-02-08	Deborah Elizabeth Bertenshaw	Retroviral protease inhibitors

1993
- 1993-10-29 CA CA002141570A patent/CA2141570A1/en not_active Abandoned
- 1993-10-29 ES ES94901230T patent/ES2097023T3/es not_active Expired - Lifetime
- 1993-10-29 DE DE69307726T patent/DE69307726T2/de not_active Expired - Fee Related
- 1993-10-29 AU AU55892/94A patent/AU5589294A/en not_active Abandoned
- 1993-10-29 AT AT94901230T patent/ATE148105T1/de not_active IP Right Cessation
- 1993-10-29 WO PCT/US1993/010460 patent/WO1994010133A1/en active IP Right Grant
- 1993-10-29 EP EP94901230A patent/EP0666841B1/de not_active Expired - Lifetime
- 1993-10-29 DK DK94901230.6T patent/DK0666841T3/da active
1997
- 1997-04-04 GR GR970400711T patent/GR3023044T3/el unknown

Also Published As

Publication number	Publication date
EP0666841A1 (de)	1995-08-16
AU5589294A (en)	1994-05-24
CA2141570A1 (en)	1994-05-11
DK0666841T3 (da)	1997-02-10
WO1994010133A1 (en)	1994-05-11
DE69307726T2 (de)	1997-06-05
ES2097023T3 (es)	1997-03-16
GR3023044T3 (en)	1997-07-30
EP0666841B1 (de)	1997-01-22
DE69307726D1 (de)	1997-03-06

Publication	Publication Date	Title
ATE234279T1 (de)	2003-03-15	Sulfonylalkanoylaminohydroxyethylaminosulfamids urn verwendbar als retrovirale proteasehemmer
GR3024181T3 (en)	1997-10-31	N-(alkanoylamino-2-hydroxypropyl)-sulfonamides useful as retroviral protease inhibitors.
FI950651A0 (fi)	1995-02-14	Retrovirusproteaasi-inhibiittoreina käyttökelpoisia sulfonyylialkanoyyliaminohydroksietyyliaminosulfoniamideja
DK0558603T3 (da)	1998-12-14	Retrovirale proteaseinhibitorer
DE69132423D1 (de)	2000-10-26	Inhibitoren retroviraler Proteasen
ATE148105T1 (de)	1997-02-15	Succinoylaminohydroxyäthylaminosulfamidsäureder vate und ihre verwendung als retrovirale proteasehemmer
GR1001393B (el)	1993-10-29	Παράγωγα ιμιδαζο[2,1-Β] 3] βενζαζεπίνης, συν?έσεις και μέ?οδος χρήσεως.

Legal Events

Date	Code	Title	Description
1997-09-15	UEP	Publication of translation of european patent specification
2009-07-15	REN	Ceased due to non-payment of the annual fee