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ATA3552000A - Xylosyltransferase-gen - Google Patents

Xylosyltransferase-gen

Info

Publication number
ATA3552000A
ATA3552000A AT0035500A AT3552000A ATA3552000A AT A3552000 A ATA3552000 A AT A3552000A AT 0035500 A AT0035500 A AT 0035500A AT 3552000 A AT3552000 A AT 3552000A AT A3552000 A ATA3552000 A AT A3552000A
Authority
AT
Austria
Prior art keywords
transferase gene
xylosyl
less
glycoprotein
human protein
Prior art date
Application number
AT0035500A
Other languages
English (en)
Other versions
AT409381B (de
Inventor
Richard Dipl Ing Strasser
Jan Dr Mucha
Lukas Dipl Ing Dr Mach
Friedrich Dipl Ing Dr Altmann
Iain B Dr Wilson
Herta Mag Dr Steinkellner
Original Assignee
Gloessl Josef Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3672559&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATA3552000(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gloessl Josef Dr filed Critical Gloessl Josef Dr
Priority to AT0035500A priority Critical patent/AT409381B/de
Priority to ES01919367.1T priority patent/ES2252208T5/es
Priority to EP05108014.1A priority patent/EP1621633B1/de
Priority to AT01919367T priority patent/ATE312931T1/de
Priority to KR1020077011024A priority patent/KR100859919B1/ko
Priority to PCT/EP2001/002352 priority patent/WO2001064901A1/en
Priority to KR1020027011341A priority patent/KR100861437B1/ko
Priority to US10/220,467 priority patent/US7205137B2/en
Priority to DK05108014.1T priority patent/DK1621633T3/da
Priority to KR1020107023909A priority patent/KR101185123B1/ko
Priority to PT51080141T priority patent/PT1621633E/pt
Priority to JP2001563590A priority patent/JP5279976B2/ja
Priority to ES05108014.1T priority patent/ES2460672T3/es
Priority to AU46495/01A priority patent/AU781010B2/en
Priority to DE60115863.6T priority patent/DE60115863T3/de
Priority to KR1020087019207A priority patent/KR20080077296A/ko
Priority to EP01919367.1A priority patent/EP1263968B2/de
Priority to KR1020097019435A priority patent/KR20090101981A/ko
Priority to CA2402015A priority patent/CA2402015C/en
Priority to DK01919367.1T priority patent/DK1263968T4/da
Publication of ATA3552000A publication Critical patent/ATA3552000A/de
Publication of AT409381B publication Critical patent/AT409381B/de
Application granted granted Critical
Priority to US11/684,898 priority patent/US20070186311A1/en
Priority to US13/428,777 priority patent/US20120331578A1/en
Priority to JP2013005404A priority patent/JP2013116113A/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1077—Pentosyltransferases (2.4.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/02—Pentosyltransferases (2.4.2)
    • C12Y204/02038—Glycoprotein 2-beta-D-xylosyltransferase (2.4.2.38)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01024—Alpha-mannosidase (3.2.1.24)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/0105—Alpha-N-acetylglucosaminidase (3.2.1.50)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01052—Beta-N-acetylhexosaminidase (3.2.1.52)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
AT0035500A 2000-03-03 2000-03-03 Xylosyltransferase-gen AT409381B (de)

Priority Applications (23)

Application Number Priority Date Filing Date Title
AT0035500A AT409381B (de) 2000-03-03 2000-03-03 Xylosyltransferase-gen
ES05108014.1T ES2460672T3 (es) 2000-03-03 2001-03-02 Glicoproteínas producidas en plantas con una expresión suprimida de la beta 1,2-xilosiltransferasa
DE60115863.6T DE60115863T3 (de) 2000-03-03 2001-03-02 Beta 1, 2-xylosyltransferase gen aus arabidopsis
AT01919367T ATE312931T1 (de) 2000-03-03 2001-03-02 Beta 1, 2-xylosyltransferase gen aus arabidopsis
KR1020077011024A KR100859919B1 (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타1,2-크실로실트랜스퍼라제-유전자
PCT/EP2001/002352 WO2001064901A1 (en) 2000-03-03 2001-03-02 Beta 1, 2-xylosyltransferase-gene from arabidopsis
KR1020027011341A KR100861437B1 (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타1,2-크실로실트랜스퍼라제-유전자
US10/220,467 US7205137B2 (en) 2000-03-03 2001-03-02 β1,2-xylosyltransferase-gene from arabidopsis
DK05108014.1T DK1621633T3 (da) 2000-03-03 2001-03-02 Glycoproteiner produceret i planter med undertrykt ekspression af beta 1,2-xylosyltransferase
KR1020107023909A KR101185123B1 (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타 1,2-크실로실트랜스퍼라제-유전자
PT51080141T PT1621633E (pt) 2000-03-03 2001-03-02 Glicoproteínas produzidas em plantas com supressão da expressão de beta 1,2-xilosiltransferase
JP2001563590A JP5279976B2 (ja) 2000-03-03 2001-03-02 アラビドプシス由来β１，２−キシロシルトランスフェラーゼ遺伝子
ES01919367.1T ES2252208T5 (es) 2000-03-03 2001-03-02 Gen de beta 1,2 xilosil transferasa procedente de Arabidopsis
AU46495/01A AU781010B2 (en) 2000-03-03 2001-03-02 Beta 1, 2-xylosyltransferase-gene from arabidopsis
EP05108014.1A EP1621633B1 (de) 2000-03-03 2001-03-02 Glykoproteine die in Pflanzen mit unterdrückter Expression der Beta 1, 2-xylosyltransferase produziert sind.
KR1020087019207A KR20080077296A (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타1,2-크실로실트랜스퍼라제-유전자
EP01919367.1A EP1263968B2 (de) 2000-03-03 2001-03-02 Beta 1, 2-xylosyltransferase gen aus arabidopsis
KR1020097019435A KR20090101981A (ko) 2000-03-03 2001-03-02 아라비돕시스로부터의 베타 1,2-크실로실트랜스퍼라제-유전자
CA2402015A CA2402015C (en) 2000-03-03 2001-03-02 Beta 1, 2-xylosyltransferase-gene from arabidopsis
DK01919367.1T DK1263968T4 (da) 2000-03-03 2001-03-02 Beta 1,2-xylosyltransferasegen fra arabidopsis
US11/684,898 US20070186311A1 (en) 2000-03-03 2007-03-12 BETA 1,2-xylosyltransferase-gene from arabidopsis
US13/428,777 US20120331578A1 (en) 2000-03-03 2012-03-23 Method for Producing Recombinant Glycoproteins Having Beta1,2-Bound Xylose Residues
JP2013005404A JP2013116113A (ja) 2000-03-03 2013-01-16 アラビドプシス由来β１，２−キシロシルトランスフェラーゼ遺伝子

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0035500A AT409381B (de) 2000-03-03 2000-03-03 Xylosyltransferase-gen

Publications (2)

Publication Number Publication Date
ATA3552000A true ATA3552000A (de) 2001-12-15
AT409381B AT409381B (de) 2002-07-25

Family

ID=3672559

Family Applications (2)

Application Number Title Priority Date Filing Date
AT0035500A AT409381B (de) 2000-03-03 2000-03-03 Xylosyltransferase-gen
AT01919367T ATE312931T1 (de) 2000-03-03 2001-03-02 Beta 1, 2-xylosyltransferase gen aus arabidopsis

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT01919367T ATE312931T1 (de) 2000-03-03 2001-03-02 Beta 1, 2-xylosyltransferase gen aus arabidopsis

Country Status (12)

Country Link
US (3) US7205137B2 (de)
EP (2) EP1263968B2 (de)
JP (2) JP5279976B2 (de)
KR (5) KR100861437B1 (de)
AT (2) AT409381B (de)
AU (1) AU781010B2 (de)
CA (1) CA2402015C (de)
DE (1) DE60115863T3 (de)
DK (2) DK1621633T3 (de)
ES (2) ES2460672T3 (de)
PT (1) PT1621633E (de)
WO (1) WO2001064901A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE475714T1 (de) 1998-12-09 2010-08-15 Phyton Holdings Llc Verfahren zur herstellung von glycoprotein mit menschlichem glycosylierungsbild
DE60044858D1 (de) 1999-10-26 2010-09-30 Stichting Dienst Landbouwkundi Säugetierartige Glykosylierung in Pflanzen
US20040214273A1 (en) 2001-01-19 2004-10-28 Kazuhito Fujiyama Method for secretory production of glycoprotein having human-type sugar chain using plant cell
CA2478294C (en) 2002-03-19 2013-09-03 Plant Research International B.V. Gntiii (udp-n-acetylglucosamine:beta-d mannoside beta (1,4)-n-acetylglucosaminyltransferase iii) expression in plants
EP1485486B1 (de) 2002-03-19 2012-11-21 Stichting Dienst Landbouwkundig Onderzoek Optimierung von glycanprozessierung in pflanzen
CL2003002461A1 (es) 2002-11-27 2005-01-07 Dow Chemical Company Agroscien Inmunoglobulina que comprende al menos un glicano afucosilado, composicion que la contiene, secuencia nucleotidica y vector que la comprende, procedimiento para producir dicha inmunoglobulina en plantas.
ATE426033T1 (de) 2003-08-11 2009-04-15 Greenovation Biotech Gmbh Promoter sequenzen aus moos und dessen verwendung
US20090060921A1 (en) * 2006-01-17 2009-03-05 Biolex Therapeutics, Inc. Glycan-optimized anti-cd20 antibodies
MX2008009221A (es) * 2006-01-17 2008-11-27 Biolex Therapeutics Inc Composiciones y metodos para la humanizacion y optimizacion de n-glicanos en plantas.
CN101405395A (zh) * 2006-03-23 2009-04-08 拜尔生物科学公司 编码烟草β-1,2-木糖基转移酶的新核苷酸序列
KR101426667B1 (ko) 2007-04-17 2014-08-06 스티칭 디엔스트 랜드보위쿤디그 온데조에크 비-포유동물 글리코실트랜스퍼라제의 발현에 의한 식물에서의 포유동물형 글리코실화
AU2008258254B2 (en) 2007-06-07 2014-07-03 Agriculture And Agri-Food Canada Nanocarrier based plant transfection and transduction
EP2789686A1 (de) 2013-04-11 2014-10-15 Greenovation Biotech GmbH Expression von phosphorylierten Glycoproteinen in Pflanzen
JP6934666B2 (ja) * 2018-01-18 2021-09-15 国立研究開発法人産業技術総合研究所 植物細胞においてキシロース修飾タンパク質を製造する方法、コアオリゴ糖修飾タンパク質を製造する方法、及びプロテオグリカンを製造する方法
EP3871687A1 (de) 2020-02-27 2021-09-01 eleva GmbH Enzymersatztherapie zur behandlung der pompe-krankheit

Family Cites Families (8)

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Publication number Priority date Publication date Assignee Title
DE69631540T2 (de) * 1995-11-23 2005-01-27 Cancer Research Technology Ltd. Materialien und methoden mit bezug zur identifizierung und sequenzierung des krebs-suszeptilitaetsgens brca2 und dessen anwendungen
WO1999029835A1 (en) * 1997-12-08 1999-06-17 Board Of Trustees Of The University Of Arkansas PURIFIED β1,2-XYLOSYLTRANSFERASE AND USES THEREOF
DE19754622A1 (de) † 1997-12-09 1999-06-10 Antje Von Dr Schaewen Pflanzliche GntI-Sequenzen und Verwendung derselben zur Gewinnung von Pflanzen mit verminderter oder fehlender N-Acetylglucosaminyltransferase I (GnTI)-Aktivität
US6638731B2 (en) * 1997-12-19 2003-10-28 Pharmacia And Upjohn Company Human sel-10 polypeptides and polynucleotides that encode them
US6207811B1 (en) * 1998-03-18 2001-03-27 Karl Tryggvason Nephrin gene and protein
JP4351807B2 (ja) * 1998-08-11 2009-10-28 ダーウィン・ディスカバリー・リミテッド マウスのｓｃｕｒｆｙの表現型を引き起こす遺伝子およびそのヒトのオルソログの同定
EP1033405A3 (de) * 1999-02-25 2001-08-01 Ceres Incorporated DNS-fragmente mit bestimmter Sequenz und die dadurch kodierte Polypeptide
WO2001029242A2 (en) * 1999-10-21 2001-04-26 Monsanto Company Post-translational modification of recombinant proteins produced in plants

Also Published As

Publication number Publication date
AU781010B2 (en) 2005-04-28
KR100859919B1 (ko) 2008-09-23
US20040121325A1 (en) 2004-06-24
DK1621633T3 (da) 2014-05-19
EP1263968A1 (de) 2002-12-11
ES2252208T5 (es) 2014-11-04
US20070186311A1 (en) 2007-08-09
KR20100119005A (ko) 2010-11-08
PT1621633E (pt) 2014-07-18
EP1621633A3 (de) 2006-02-08
DE60115863D1 (de) 2006-01-19
EP1621633B1 (de) 2014-04-16
DK1263968T3 (da) 2006-05-01
JP2004500096A (ja) 2004-01-08
AT409381B (de) 2002-07-25
JP5279976B2 (ja) 2013-09-04
KR100861437B1 (ko) 2008-10-02
EP1263968B2 (de) 2014-09-10
ES2252208T3 (es) 2006-05-16
WO2001064901A1 (en) 2001-09-07
EP1621633A2 (de) 2006-02-01
AU4649501A (en) 2001-09-12
JP2013116113A (ja) 2013-06-13
CA2402015C (en) 2012-07-17
ATE312931T1 (de) 2005-12-15
US7205137B2 (en) 2007-04-17
DE60115863T3 (de) 2015-01-22
US20120331578A1 (en) 2012-12-27
DK1263968T4 (da) 2014-11-03
ES2460672T3 (es) 2014-05-14
KR20080077296A (ko) 2008-08-21
CA2402015A1 (en) 2001-09-07
DE60115863T2 (de) 2006-08-10
EP1263968B1 (de) 2005-12-14
KR20070058018A (ko) 2007-06-07
KR20030030987A (ko) 2003-04-18
KR20090101981A (ko) 2009-09-29
KR101185123B1 (ko) 2012-09-21

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