AT383808B - Verfahren zur herstellung von penemen - Google Patents

Verfahren zur herstellung von penemen

Info

Publication number: AT383808B
Authority: AT; Austria
Prior art keywords: penemas; producing; producing penemas
Prior art date: 1983-08-11

Application number

AT0255884A

Other languages

English (en)

Other versions

ATA255884A (de

Inventor

Carlo Battistini

Maurizio Foglio

Giovanni Franceschi

Cosimo Scarafile

Original Assignee

Erba Farmitalia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-08-11

Filing date

1984-08-07

Publication date

1987-08-25

1984-08-07 Application filed by Erba Farmitalia filed Critical Erba Farmitalia

1987-01-15 Publication of ATA255884A publication Critical patent/ATA255884A/de

1987-08-25 Application granted granted Critical

1987-08-25 Publication of AT383808B publication Critical patent/AT383808B/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/04—Preparation
- C07D499/06—Preparation by forming the ring or condensed ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)

AT0255884A 1983-08-11 1984-08-07 Verfahren zur herstellung von penemen AT383808B (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB838321677A GB8321677D0 (en)	1983-08-11	1983-08-11	Preparation of penems

Publications (2)

Publication Number	Publication Date
ATA255884A ATA255884A (de)	1987-01-15
AT383808B true AT383808B (de)	1987-08-25

Family

ID=10547172

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT0255884A AT383808B (de)	1983-08-11	1984-08-07	Verfahren zur herstellung von penemen

Country Status (20)

Country	Link
US (1)	US4631150A (de)
JP (1)	JPS6058988A (de)
KR (1)	KR910002098B1 (de)
AT (1)	AT383808B (de)
BE (1)	BE900316A (de)
CA (1)	CA1279640C (de)
CH (1)	CH663024A5 (de)
DE (1)	DE3429102A1 (de)
DK (1)	DK167926B1 (de)
ES (1)	ES8600306A1 (de)
FI (1)	FI83521C (de)
FR (1)	FR2550533B1 (de)
GB (2)	GB8321677D0 (de)
GR (1)	GR80102B (de)
HU (1)	HU192415B (de)
IL (1)	IL72612A (de)
IT (1)	IT1209578B (de)
NL (1)	NL8402478A (de)
PT (1)	PT79065B (de)
SE (1)	SE463514B (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8416651D0 (en) *	1984-06-29	1984-08-01	Erba Farmitalia	Penem derivatives
DE3688960D1 (de) *	1985-09-11	1993-10-07	Ciba Geigy	Synthese von Beta-Lactamverbindungen.
US5215997A (en) *	1985-09-11	1993-06-01	Ciba-Geigy Corporation	Synthesis of beta-lactam compounds
EP0232966B1 (de) *	1986-01-17	1997-10-08	Beecham Group Plc	Verfahren zur Herstellung von Penem Derivaten und Zwischenprodukte zu dieser Herstellung
EP0233155A1 (de) *	1986-02-14	1987-08-19	Ciba-Geigy Ag	Aminoacyloxymethyl-Verbindungen
US5215891A (en) *	1986-10-15	1993-06-01	Farmitalia Carlo Erba	Process for preparing penems
SG45180A1 (en) *	1987-02-17	1998-01-16	Ciba Geigy Ag	A process for the manufacture of 4-acetoxy-3- hydroxy-ethyl-azetidinone
US5312914A (en) *	1987-02-17	1994-05-17	Ciba-Geigy Corp	Process for the manufacture of 4-acetoxy-3-hydroxyethyl-azetidinone
GB8713515D0 (en) *	1987-06-10	1987-07-15	Erba Farmitalia	Methoxymethyl compounds
US5364768A (en) *	1987-07-07	1994-11-15	Farmitalia Carlo Erba S.R.L.	Process for the preparation of penems
GB2206578B (en) *	1987-07-07	1991-07-03	Erba Carlo Spa	Process for the preparation of penems
US4992543A (en) *	1988-10-19	1991-02-12	Pfizer Inc.	Penem derivatives
US5191075A (en) *	1988-10-19	1993-03-02	Pfizer Inc	Process for the preparation of penems
CA2001203C (en) *	1988-10-24	2001-02-13	Thomas P. Demuth, Jr.	Novel antimicrobial dithiocarbamoyl quinolones
EP0366189A3 (de) *	1988-10-24	1992-01-02	Norwich Eaton Pharmaceuticals, Inc.	Antimikrobielle Lactam-Quinolone
US5328908A (en) *	1988-10-24	1994-07-12	Procter & Gamble Pharmaceuticals, Inc.	Antimicrobial quinolone thioureas
US5180719A (en) *	1988-10-24	1993-01-19	Norwich Eaton Pharmaceuticals, Inc.	Antimicrobial quinolonyl lactam esters
US5273973A (en) *	1988-10-24	1993-12-28	Norwich Eaton Pharmaceuticals, Inc.	Antimicrobial quinolonyl esters
US5491139A (en) *	1988-10-24	1996-02-13	The Procter & Gamble Company	Antimicrobial quinolonyl lactams
US5198544A (en) *	1989-04-29	1993-03-30	Hoechst Aktiengesellschaft	Process for the preparation of penem compounds
EP0399228A1 (de) *	1989-04-29	1990-11-28	Hoechst Aktiengesellschaft	Verfahren zur Herstellung von Penemverbindungen
WO1991016327A1 (en)	1990-04-18	1991-10-31	Norwich Eaton Pharmaceuticals, Inc.	Antimicrobial quinolonyl lactams
US5399679A (en) *	1992-06-16	1995-03-21	Farmitalia Carlo Erba S.R.L.	(1'R,3S,4R)4-acylthio azetidinones
EP0597401A3 (de) *	1992-11-11	1995-07-26	Takeda Chemical Industries Ltd	Herstellung von Penem-Verbindungen.
IT1286558B1 (it) *	1996-02-27	1998-07-15	Menarini Farma Ind	Processo per la preparazione di 2-alogenometil-penems e loro uso per la preparazione di penems antibatterici
CN100417654C (zh) *	2004-01-09	2008-09-10	中国医学科学院医药生物技术研究所	2-苯羧酸酯青霉烯类化合物及其制备方法和应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4500457A (en) *	1977-05-09	1985-02-19	Ciba-Geigy Corporation	Process for preparing thia-aza compounds with a beta-lactam ring
US4168314A (en) *	1977-11-17	1979-09-18	Merck & Co., Inc.	6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
EP0003960B1 (de) *	1978-02-02	1983-06-29	Ciba-Geigy Ag	6-Substituierte Thia-Azaverbindungen, ihre Herstellung und diese enthaltende pharmazeutische Präparate
EP0013067A1 (de) *	1978-12-22	1980-07-09	Beecham Group Plc	Bicyclische beta-Lactam antibakterielle Mittel, ihre Verwendung in pharmazeutischen Zusammensetzungen, Verfahren zu ihrer Herstellung und Zwischenprodukte zur Verwendung in solchen Verfahren
FI75163C (fi) *	1979-02-24	1988-05-09	Erba Farmitalia	Foerfarande foer framstaellning av nya penemkarboxylsyror eller -estrar.
US4269771A (en) *	1979-04-06	1981-05-26	Farmitalia Carlo Erba	Total synthesis of 7-oxo-4-thia-1-azabicyclo-[3,2,0]-heptane-2-carboxyl derivatives useful as β-lactamase inhibitors and antibacterial agents
CH651037A5 (de) *	1980-06-06	1985-08-30	Sankyo Co	Penem-3-carbonsaeurederivate und verfahren zu deren herstellung.
GB2079744A (en) *	1980-07-04	1982-01-27	Erba Farmitalia	6-Alkyl-2-functionalized penems
US4347183A (en) *	1981-02-02	1982-08-31	Schering Corporation	Process for the synthesis of penems and carbapenems
JPS588084A (ja) *	1981-07-08	1983-01-18	Takeda Chem Ind Ltd	（６ｒ）−置換−（５ｒ）−ペネム−３−カルボン酸誘導体およびその製造法
US4411906A (en) *	1981-11-25	1983-10-25	Schering Corporation	(5R,6S,8R)-6-(1-Hydroxyethyl)-2-(2-fluoroethylthio)-penem-3-carboxylates
US4508649A (en) *	1981-12-11	1985-04-02	Farmitalia Carlo Erba	Process for preparing optically active penems
US4443373A (en) *	1982-03-30	1984-04-17	Schering Corporation	Process for the production of antibiotic penems
US4584133A (en) *	1983-11-07	1986-04-22	Schering Corporation	Process for the production of penems

1983
- 1983-08-11 GB GB838321677A patent/GB8321677D0/en active Pending
1984
- 1984-08-03 ES ES534892A patent/ES8600306A1/es not_active Expired
- 1984-08-06 IT IT8422234A patent/IT1209578B/it active
- 1984-08-06 US US06/637,878 patent/US4631150A/en not_active Expired - Lifetime
- 1984-08-07 DE DE19843429102 patent/DE3429102A1/de not_active Ceased
- 1984-08-07 IL IL72612A patent/IL72612A/xx not_active IP Right Cessation
- 1984-08-07 SE SE8404004A patent/SE463514B/sv not_active IP Right Cessation
- 1984-08-07 AT AT0255884A patent/AT383808B/de not_active IP Right Cessation
- 1984-08-07 FR FR8412466A patent/FR2550533B1/fr not_active Expired
- 1984-08-08 DK DK382084A patent/DK167926B1/da not_active IP Right Cessation
- 1984-08-08 FI FI843111A patent/FI83521C/fi not_active IP Right Cessation
- 1984-08-08 JP JP59165031A patent/JPS6058988A/ja active Granted
- 1984-08-08 BE BE0/213460A patent/BE900316A/fr not_active IP Right Cessation
- 1984-08-09 GB GB08420236A patent/GB2144743B/en not_active Expired
- 1984-08-10 GR GR80102A patent/GR80102B/el unknown
- 1984-08-10 NL NL8402478A patent/NL8402478A/xx not_active Application Discontinuation
- 1984-08-10 KR KR1019840004797A patent/KR910002098B1/ko not_active IP Right Cessation
- 1984-08-10 CA CA000460795A patent/CA1279640C/en not_active Expired - Fee Related
- 1984-08-10 PT PT79065A patent/PT79065B/pt not_active IP Right Cessation
- 1984-08-10 CH CH3855/84A patent/CH663024A5/de not_active IP Right Cessation
- 1984-08-10 HU HU843056A patent/HU192415B/hu not_active IP Right Cessation

Also Published As

Publication number	Publication date
US4631150A (en)	1986-12-23
SE8404004D0 (sv)	1984-08-07
IL72612A (en)	1988-06-30
HU192415B (en)	1987-06-29
KR850001757A (ko)	1985-04-01
FR2550533A1 (fr)	1985-02-15
SE8404004L (sv)	1985-02-12
CH663024A5 (de)	1987-11-13
SE463514B (sv)	1990-12-03
IT8422234A0 (it)	1984-08-06
GB2144743B (en)	1987-01-28
JPS6058988A (ja)	1985-04-05
GB2144743A (en)	1985-03-13
FI843111A (fi)	1985-02-12
ATA255884A (de)	1987-01-15
DK382084A (da)	1985-02-12
KR910002098B1 (ko)	1991-04-03
IT1209578B (it)	1989-08-30
PT79065A (en)	1984-09-01
IL72612A0 (en)	1984-11-30
ES534892A0 (es)	1985-09-16
FI83521C (fi)	1991-07-25
PT79065B (en)	1986-11-14
ES8600306A1 (es)	1985-09-16
DE3429102A1 (de)	1985-02-28
GB8321677D0 (en)	1983-09-14
CA1279640C (en)	1991-01-29
DK167926B1 (da)	1994-01-03
GB8420236D0 (en)	1984-09-12
FI843111A0 (fi)	1984-08-08
GR80102B (en)	1984-12-14
BE900316A (fr)	1985-02-08
FI83521B (fi)	1991-04-15
JPH037675B2 (de)	1991-02-04
HUT34984A (en)	1985-05-28
FR2550533B1 (fr)	1987-01-30
DK382084D0 (da)	1984-08-08
NL8402478A (nl)	1985-03-01

Publication	Publication Date	Title
DE3486188D1 (de)	1993-09-02	Verfahren zur herstellung von l-tyrosin.
AT383808B (de)	1987-08-25	Verfahren zur herstellung von penemen
AT385757B (de)	1988-05-10	Verfahren zur herstellung von cephalosporinen
ATA224084A (de)	1990-07-15	Verfahren zur herstellung von alkoholen
AT379831B (de)	1986-03-10	Verfahren zur herstellung von kristallen
AT374827B (de)	1984-06-12	Verfahren zur herstellung von cholesterase
AT389512B (de)	1989-12-27	Verfahren zur herstellung von 3-chlormethylchinuclidin
AT386828B (de)	1988-10-25	Verfahren zur herstellung von neuen acylaminomitosanen
AT367436B (de)	1982-07-12	Verfahren zur herstellung von copolymerisaten
ATA199684A (de)	1989-09-15	Verfahren zur herstellung von 6-deoxyanthracyclinonen
AT387024B (de)	1988-11-25	Verfahren zur herstellung von aspartam
AT380480B (de)	1986-05-26	Verfahren zur herstellung von anthracyclinglykosiden
ATA178085A (de)	1992-09-15	Verfahren zur herstellung von 1-thiosubstituierten n-methyl-2-nitroaethenaminen
ATA252985A (de)	1993-02-15	Verfahren zur herstellung von
AT384024B (de)	1987-09-25	Verfahren zur herstellung von azinomethylrifamycinen
AT388374B (de)	1989-06-12	Verfahren zur herstellung von n-sulfonylaryloxybenzamiden
ATA201283A (de)	1991-04-15	Verfahren zur herstellung von carboxyalkyldipeptiden
ATA319282A (de)	1983-11-15	Verfahren zur herstellung von reinem 3-amino-crotonitril
DE3380957D1 (de)	1990-01-18	Verfahren zur herstellung von 5-acyloxymethyl-oxazolidin-2-on-derivaten.
DE3485103D1 (de)	1991-10-31	Verfahren zur herstellung von polyglycidylamin-derivaten.
AT381723B (de)	1986-11-25	Verfahren zur herstellung von cephalosporin c
ATA328581A (de)	1982-09-15	Verfahren zur herstellung von 1-phenoxy-3-amino- 2-propanolen
ATA119884A (de)	1986-05-15	Verfahren zur herstellung von cephalosporinantibiotika
ATA535281A (de)	1985-03-15	Verfahren zur herstellung von phenoxyisobutters\|ureestern
ATA358482A (de)	1983-06-15	Verfahren zur herstellung von o-trimethylsilyl -cellulose

Legal Events

Date	Code	Title	Description
1997-10-15	ELJ	Ceased due to non-payment of the annual fee