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AT316515B - Process for the preparation of the new racemic or optically active 1- (2 ', 5'-dichlorophenoxy) -2-hydroxy-3-tert. butylaminopropane and its acid addition salts - Google Patents

Process for the preparation of the new racemic or optically active 1- (2 ', 5'-dichlorophenoxy) -2-hydroxy-3-tert. butylaminopropane and its acid addition salts

Info

Publication number
AT316515B
AT316515B AT170072A AT170072A AT316515B AT 316515 B AT316515 B AT 316515B AT 170072 A AT170072 A AT 170072A AT 170072 A AT170072 A AT 170072A AT 316515 B AT316515 B AT 316515B
Authority
AT
Austria
Prior art keywords
butylaminopropane
dichlorophenoxy
tert
hydroxy
preparation
Prior art date
Application number
AT170072A
Other languages
German (de)
Inventor
Andor Haejos Dr
Marton Fekete Dr
Marianne Kuerti Dr
Sandor Elek Dr
Istvan Polgari Dr
Istvan Elekes Dr
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Application granted granted Critical
Publication of AT316515B publication Critical patent/AT316515B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/34—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT170072A 1971-03-17 1972-03-01 Process for the preparation of the new racemic or optically active 1- (2 ', 5'-dichlorophenoxy) -2-hydroxy-3-tert. butylaminopropane and its acid addition salts AT316515B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUGO001156 1971-03-17

Publications (1)

Publication Number Publication Date
AT316515B true AT316515B (en) 1974-07-10

Family

ID=10996691

Family Applications (1)

Application Number Title Priority Date Filing Date
AT170072A AT316515B (en) 1971-03-17 1972-03-01 Process for the preparation of the new racemic or optically active 1- (2 ', 5'-dichlorophenoxy) -2-hydroxy-3-tert. butylaminopropane and its acid addition salts

Country Status (19)

Country Link
JP (1) JPS5310581B1 (en)
AT (1) AT316515B (en)
AU (1) AU461159B2 (en)
BE (1) BE780719A (en)
CA (1) CA1002537A (en)
CH (1) CH569692A5 (en)
CS (1) CS163270B2 (en)
DK (1) DK133872B (en)
ES (1) ES401235A1 (en)
FI (1) FI55025C (en)
FR (1) FR2130284B1 (en)
GB (1) GB1337921A (en)
IL (1) IL38870A (en)
NL (1) NL170626C (en)
NO (1) NO134836C (en)
PL (1) PL88985B1 (en)
SE (1) SE384021B (en)
SU (1) SU496721A3 (en)
YU (1) YU35435B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU172137B (en) 1976-03-02 1978-06-28 Gyogyszerkutato Intezet Process for preparing substituted derivatives of the phenoxy-propanolamine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1236523C2 (en) * 1962-02-15 1975-06-12 Sanol-Arzneimittel Dr. Schwarz Gmbh, 4019 Monheim PROCESS FOR THE PRODUCTION OF BASIC PHENYLAETHERS AND THEIR SALTS

Also Published As

Publication number Publication date
DE2213044B2 (en) 1977-05-26
ES401235A1 (en) 1975-02-16
FR2130284A1 (en) 1972-11-03
GB1337921A (en) 1973-11-21
DK133872B (en) 1976-08-02
AU461159B2 (en) 1975-04-29
YU35435B (en) 1981-02-28
DE2213044A1 (en) 1972-09-28
PL88985B1 (en) 1976-10-30
CA1002537A (en) 1976-12-28
SU496721A3 (en) 1975-12-25
NL170626C (en) 1982-12-01
NL7203323A (en) 1972-09-19
AU3965972A (en) 1973-09-13
JPS5310581B1 (en) 1978-04-14
IL38870A0 (en) 1972-05-30
NL170626B (en) 1982-07-01
YU63972A (en) 1980-06-30
IL38870A (en) 1975-08-31
DK133872C (en) 1976-12-27
FR2130284B1 (en) 1975-10-10
NO134836C (en) 1976-12-21
CH569692A5 (en) 1975-11-28
SE384021B (en) 1976-04-12
BE780719A (en) 1972-07-03
CS163270B2 (en) 1975-08-29
NO134836B (en) 1976-09-13
FI55025B (en) 1979-01-31
FI55025C (en) 1979-05-10

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Legal Events

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ELA Expired due to lapse of time