AR208397A1 - PROCEDURE FOR THE PREPARATION OF 1-PYRIDYLOXY-2-HYDROXY-3-AMINO-PROPANO1-PIRAZINYLOXY-2-HYDROXY-3-AMINO-PROPANE AND 1-PYRIMIDINYLOXY-2-HYDROXY-3-AMINO-PROPAN COMPOUNDS - Google Patents
PROCEDURE FOR THE PREPARATION OF 1-PYRIDYLOXY-2-HYDROXY-3-AMINO-PROPANO1-PIRAZINYLOXY-2-HYDROXY-3-AMINO-PROPANE AND 1-PYRIMIDINYLOXY-2-HYDROXY-3-AMINO-PROPAN COMPOUNDSInfo
- Publication number
- AR208397A1 AR208397A1 AR257054A AR25705474A AR208397A1 AR 208397 A1 AR208397 A1 AR 208397A1 AR 257054 A AR257054 A AR 257054A AR 25705474 A AR25705474 A AR 25705474A AR 208397 A1 AR208397 A1 AR 208397A1
- Authority
- AR
- Argentina
- Prior art keywords
- hydroxy
- amino
- pirazinyloxy
- propano1
- pyrimidinyloxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH244473A CH584209A5 (en) | 1973-02-20 | 1973-02-20 | 3-amino-2-hydroxypropoxy substd. diazines and pyridines - with beta-adrenergic blocking or stimulating activity |
| FI193/74A FI60391C (en) | 1973-02-20 | 1974-01-23 | ANALOGIFICATION OF FRAMSTATION WITH BETA-RECEPTOR-ACTIVE 1-HETEROCYCLYLOXY-3-AMINO-2-PROPANOLFOERING |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR208397A1 true AR208397A1 (en) | 1976-12-27 |
Family
ID=25690464
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR257054A AR208397A1 (en) | 1973-02-20 | 1974-01-01 | PROCEDURE FOR THE PREPARATION OF 1-PYRIDYLOXY-2-HYDROXY-3-AMINO-PROPANO1-PIRAZINYLOXY-2-HYDROXY-3-AMINO-PROPANE AND 1-PYRIMIDINYLOXY-2-HYDROXY-3-AMINO-PROPAN COMPOUNDS |
| AR257055A AR207133A1 (en) | 1973-02-20 | 1974-01-01 | PROCEDURE FOR THE PREPARATION OF 1-PYRIDYLOXY 1-PYRIMIDINYLOXY AND 1-PYRAZINYLOXY-2-HYDROXY-3-AMINO-PROPANE DERIVATIVES |
| AR257058A AR206801A1 (en) | 1973-02-20 | 1974-01-01 | PROCEDURE FOR THE ELABORATION OF DERIVATIVES OF 1-PIRID LOXI-2-HIDROXI-3-AMINO-PROPAN |
| AR252438A AR214612A1 (en) | 1973-02-20 | 1974-02-20 | PROCEDURE TO PREPARE NEW DERIVATIVES OF 1-PYRIDYLOXY-, 1-PIRAZINYLOXY-, 1-PYRODAZINYLOXY OR 1-PYRIMIDINYLOXY-2-HYDROXY-3-AMINO-PROPANE |
| AR257057A AR203878A1 (en) | 1973-02-20 | 1974-12-23 | PROCEDURE FOR THE PREPARATION OF 1-PYRAZINYLOXY 2-HYDROXY-3-AMINOPROPANE COMPOUNDS |
| AR264155A AR208043A1 (en) | 1973-02-20 | 1976-01-01 | PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF 1-PYRIDYLOXY 1-PYRIMIDINYLOXY AND 1-PIRAZINYLOXY-2-HYDROXY-3-AMINO PROPANE |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR257055A AR207133A1 (en) | 1973-02-20 | 1974-01-01 | PROCEDURE FOR THE PREPARATION OF 1-PYRIDYLOXY 1-PYRIMIDINYLOXY AND 1-PYRAZINYLOXY-2-HYDROXY-3-AMINO-PROPANE DERIVATIVES |
| AR257058A AR206801A1 (en) | 1973-02-20 | 1974-01-01 | PROCEDURE FOR THE ELABORATION OF DERIVATIVES OF 1-PIRID LOXI-2-HIDROXI-3-AMINO-PROPAN |
| AR252438A AR214612A1 (en) | 1973-02-20 | 1974-02-20 | PROCEDURE TO PREPARE NEW DERIVATIVES OF 1-PYRIDYLOXY-, 1-PIRAZINYLOXY-, 1-PYRODAZINYLOXY OR 1-PYRIMIDINYLOXY-2-HYDROXY-3-AMINO-PROPANE |
| AR257057A AR203878A1 (en) | 1973-02-20 | 1974-12-23 | PROCEDURE FOR THE PREPARATION OF 1-PYRAZINYLOXY 2-HYDROXY-3-AMINOPROPANE COMPOUNDS |
| AR264155A AR208043A1 (en) | 1973-02-20 | 1976-01-01 | PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF 1-PYRIDYLOXY 1-PYRIMIDINYLOXY AND 1-PIRAZINYLOXY-2-HYDROXY-3-AMINO PROPANE |
Country Status (15)
| Country | Link |
|---|---|
| AR (6) | AR208397A1 (en) |
| AT (1) | AT335455B (en) |
| BE (1) | BE811274A (en) |
| CA (1) | CA1027131A (en) |
| CS (1) | CS203970B2 (en) |
| DD (1) | DD110041A5 (en) |
| DE (1) | DE2406930A1 (en) |
| DK (1) | DK143501C (en) |
| ES (2) | ES446081A1 (en) |
| FR (1) | FR2218101B1 (en) |
| GB (1) | GB1465946A (en) |
| IE (1) | IE38839B1 (en) |
| IL (1) | IL44202A (en) |
| LU (1) | LU69415A1 (en) |
| SE (1) | SE420834B (en) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4195090A (en) * | 1973-02-20 | 1980-03-25 | Ciba-Geigy Corporation | 2-(3-Amino-2-hydroxy-propoxy)pyridine derivatives and pharmaceutical compositions therewith |
| US4000282A (en) * | 1974-12-16 | 1976-12-28 | Merck & Co., Inc. | 2-(3-tert. butyl or isopropylamino-2-hydroxypropoxy)-3-cyanopyridines |
| JPS5283759A (en) * | 1976-01-01 | 1977-07-12 | Merck & Co Inc | Substituted pyridines |
| US4092419A (en) * | 1976-06-15 | 1978-05-30 | Merck & Co., Inc. | Substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines, their preparation and use |
| US4091104A (en) * | 1976-06-15 | 1978-05-23 | Merck & Co., Inc. | Substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines, their preparation and use |
| US4060601A (en) * | 1976-06-15 | 1977-11-29 | Merck & Co., Inc. | Certain lower-alkyl amino-2'-hydroxy-propoxy pyridines |
| DE2711655A1 (en) * | 1977-03-17 | 1978-09-21 | Basf Ag | PYRIDINYL-AMINOALKYLAETHER |
| US4166851A (en) * | 1977-05-16 | 1979-09-04 | Merck & Co., Inc. | Certain imidazo(1,2a)pyridine derivatives |
| US4753673A (en) * | 1977-07-22 | 1988-06-28 | The Dow Chemical Company | Trifluoromethyl pyridinyloxyphenoxy and pyridinylthiophenoxy propanoic acids and propanols and derivatives thereof and methods of herbicidal use |
| US4279913A (en) * | 1978-01-04 | 1981-07-21 | Merck & Co., Inc. | Polysubstituted-2-(3-loweralkylamino-2-R1 O-propoxy)pyridines |
| JPS54106476A (en) * | 1978-01-04 | 1979-08-21 | Merck & Co Inc | Multiisubstituted 22*33lower alkylaminoo22 r100propoxy*pyridine |
| US4144343A (en) * | 1978-01-04 | 1979-03-13 | Merck & Co., Inc. | Heterocycle substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines |
| US4210653A (en) * | 1978-06-27 | 1980-07-01 | Merck & Co., Inc. | Pyridyloxypropanolamines |
| US4208416A (en) * | 1978-06-27 | 1980-06-17 | Merck & Co., Inc. | N-Aralkyl containing cyanopyridines |
| DK267779A (en) * | 1978-06-27 | 1979-12-28 | Merck & Co Inc | PROCEDURE FOR THE PREPARATION OF N-ARALKYLAMINO-PROPOXYCYANOPYRIDINES |
| US4294969A (en) * | 1979-01-29 | 1981-10-13 | Merck & Co., Inc. | Process for producing 2-bromo-3,5-disubstituted pyridines |
| US4393212A (en) * | 1979-01-29 | 1983-07-12 | Merck & Co., Inc. | Certain nicotinic acid esters and corresponding nicotinonitriles |
| DD150456A5 (en) * | 1979-03-01 | 1981-09-02 | Ciba Geigy Ag | PROCESS FOR THE PREPARATION OF DERIVATIVES OF 3-AMINO-1,2-PROPANDIOL |
| US4281005A (en) | 1979-03-05 | 1981-07-28 | Merck & Co., Inc. | Novel 2-pyridylimidazole compounds |
| IT1165040B (en) * | 1979-04-23 | 1987-04-22 | Isf Spa | ALCOSSIALKILIDENIDRAZINOPIRIDAZIONE AND PROCEDURE FOR THEIR PREPARATION |
| DE2943774A1 (en) * | 1979-10-26 | 1981-05-14 | 1000 Berlin Schering Ag Berlin Und Bergkamen | SUBSTITUTED PYRIDINE, METHOD FOR THEIR PRODUCTION AND THEIR USE |
| IL62602A (en) * | 1980-05-19 | 1984-06-29 | Labaz Sanofi Nv | Pyridoxine derivatives,their preparation and pharmaceutical compositions containing them |
| FR2502618A1 (en) * | 1981-03-25 | 1982-10-01 | Synthelabo | PYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
| US4517188A (en) * | 1983-05-09 | 1985-05-14 | Mead Johnson & Company | 1-Pyrimidinyloxy-3-hetaryl-alkylamino-2-propanols |
| US4598149A (en) * | 1984-03-02 | 1986-07-01 | Merck & Co., Inc. | 3-amino-2-hydroxypropyl of pyrimidin-4-one useful as antihypertensive, cardioprotective, antiarrythmic, and antianginal agents |
| US6465467B1 (en) | 1999-05-21 | 2002-10-15 | Biovitrum Ab | Certain aryl-aliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases |
| US7361671B2 (en) * | 2001-11-15 | 2008-04-22 | The Institute For Pharmaceutical Discovery, Inc. | Substituted heteroarylalkanoic acids |
| NZ536664A (en) | 2002-06-19 | 2007-07-27 | Biovitrum Ab | Piperazinylpyrazine derivative compounds, their use and preparation |
| WO2004050657A2 (en) * | 2002-11-27 | 2004-06-17 | Artesian Therapeutics, Inc. | COMPOUNDS WITH MIXED PDE-INHIBITORY AND β-ADRENERGIC ANTAGONIST OR PARTIAL AGONIST ACTIVITY FOR TREATMENT OF HEART FAILURE |
| US20080033020A1 (en) * | 2004-07-23 | 2008-02-07 | Darren Mansfield | 3-Pyridinylethylbenzamide Derivatives as Fungicides |
| MX2012003394A (en) * | 2009-09-21 | 2012-08-15 | Univ Vanderbilt | O-benzyl nicotinamide analogs as mglur5 positive allosteric modulators. |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1001631A (en) * | 1972-05-05 | 1976-12-14 | Merck Sharp And Dohme (I.A.) Corp. | 2-(3-substituted amino-2-hydroxy-propoxy)-3-substituted pyrazines and method for preparation |
-
1974
- 1974-01-01 AR AR257054A patent/AR208397A1/en active
- 1974-01-01 AR AR257055A patent/AR207133A1/en active
- 1974-01-01 AR AR257058A patent/AR206801A1/en active
- 1974-01-29 SE SE7401114A patent/SE420834B/en unknown
- 1974-02-11 IE IE255/74A patent/IE38839B1/en unknown
- 1974-02-12 CA CA192,292A patent/CA1027131A/en not_active Expired
- 1974-02-13 IL IL44202A patent/IL44202A/en unknown
- 1974-02-13 GB GB651874A patent/GB1465946A/en not_active Expired
- 1974-02-14 DE DE19742406930 patent/DE2406930A1/en not_active Ceased
- 1974-02-15 DK DK80774A patent/DK143501C/en not_active IP Right Cessation
- 1974-02-18 FR FR7405391A patent/FR2218101B1/fr not_active Expired
- 1974-02-18 LU LU69415A patent/LU69415A1/xx unknown
- 1974-02-18 DD DD176616A patent/DD110041A5/xx unknown
- 1974-02-19 BE BE141130A patent/BE811274A/en not_active IP Right Cessation
- 1974-02-19 AT AT133074A patent/AT335455B/en not_active IP Right Cessation
- 1974-02-20 AR AR252438A patent/AR214612A1/en active
- 1974-02-20 CS CS741252A patent/CS203970B2/en unknown
- 1974-12-23 AR AR257057A patent/AR203878A1/en active
-
1976
- 1976-01-01 AR AR264155A patent/AR208043A1/en active
- 1976-03-16 ES ES76446081A patent/ES446081A1/en not_active Expired
- 1976-03-16 ES ES446083A patent/ES446083A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IL44202A (en) | 1978-10-31 |
| ATA133074A (en) | 1976-07-15 |
| CA1027131A (en) | 1978-02-28 |
| CS203970B2 (en) | 1981-03-31 |
| DK143501B (en) | 1981-08-31 |
| DK143501C (en) | 1982-02-22 |
| FR2218101A1 (en) | 1974-09-13 |
| AR206801A1 (en) | 1976-08-23 |
| ES446083A1 (en) | 1977-09-16 |
| AR214612A1 (en) | 1979-07-13 |
| AR208043A1 (en) | 1976-11-22 |
| AR203878A1 (en) | 1975-10-31 |
| IE38839B1 (en) | 1978-06-07 |
| AR207133A1 (en) | 1976-09-15 |
| FR2218101B1 (en) | 1977-07-15 |
| SE420834B (en) | 1981-11-02 |
| GB1465946A (en) | 1977-03-02 |
| BE811274A (en) | 1974-08-19 |
| LU69415A1 (en) | 1975-12-09 |
| IE38839L (en) | 1974-08-20 |
| IL44202A0 (en) | 1974-06-30 |
| AT335455B (en) | 1977-03-10 |
| DD110041A5 (en) | 1974-12-05 |
| ES446081A1 (en) | 1977-06-16 |
| DE2406930A1 (en) | 1974-08-22 |
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