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Application filed by Univ PennsylvaniafiledCriticalUniv Pennsylvania
Publication of AR120259A1publicationCriticalpatent/AR120259A1/en
Medicines Containing Material From Animals Or Micro-Organisms
(AREA)
Abstract
En el presente documento se presentan cápsides de AAV y rAAV que las comprenden. En una realización, vectores que emplean una cápside de AAV descrita exhiben transducción aumentada en un tejido seleccionado en comparación con un AAV de la técnica anterior.Presented herein are AAV and rAAV capsids comprising them. In one embodiment, vectors employing a disclosed AAV capsid exhibit increased transduction in a selected tissue compared to a prior art AAV.
ARP200102894A2019-10-212020-10-20
AAV3B VARIANTS WITH ENHANCED PRODUCTION YIELD AND LIVER TROPISM
AR120259A1
(en)