AR114734A1 - POLIPÉPTIDOS INSECTICIDAS MUTANTES Av3 Y MÉTODOS PARA PRODUCIRLOS Y USARLOS - Google Patents
POLIPÉPTIDOS INSECTICIDAS MUTANTES Av3 Y MÉTODOS PARA PRODUCIRLOS Y USARLOSInfo
- Publication number
- AR114734A1 AR114734A1 ARP190102630A ARP190102630A AR114734A1 AR 114734 A1 AR114734 A1 AR 114734A1 AR P190102630 A ARP190102630 A AR P190102630A AR P190102630 A ARP190102630 A AR P190102630A AR 114734 A1 AR114734 A1 AR 114734A1
- Authority
- AR
- Argentina
- Prior art keywords
- polypeptides
- avp
- terminal
- methods
- insecticidal
- Prior art date
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 8
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 8
- 229920001184 polypeptide Polymers 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 5
- 239000002917 insecticide Substances 0.000 title 1
- 230000000749 insecticidal effect Effects 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 241000238631 Hexapoda Species 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 230000035772 mutation Effects 0.000 abstract 2
- 239000003053 toxin Substances 0.000 abstract 2
- 231100000765 toxin Toxicity 0.000 abstract 2
- 108700012359 toxins Proteins 0.000 abstract 2
- 241000242759 Actiniaria Species 0.000 abstract 1
- 239000004475 Arginine Substances 0.000 abstract 1
- 125000001433 C-terminal amino-acid group Chemical group 0.000 abstract 1
- 241000196324 Embryophyta Species 0.000 abstract 1
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 abstract 1
- 239000004472 Lysine Substances 0.000 abstract 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 1
- KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 abstract 1
- 125000000637 arginyl group Chemical group N[C@@H](CCCNC(N)=N)C(=O)* 0.000 abstract 1
- 230000037430 deletion Effects 0.000 abstract 1
- 238000012217 deletion Methods 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 239000004474 valine Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/50—Isolated enzymes; Isolated proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Insects & Arthropods (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Agronomy & Crop Science (AREA)
- Virology (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Proteínas, nucleótidos y polipéptidos insecticidas, su expresión en las plantas, métodos para producir los polipéptidos, procesos, técnicas de producción, polipéptidos, formulaciones, polipéptidos sintéticos, organismos y un proceso que aumenta el rendimiento de la producción de péptidos insecticidas desde sistemas de expresión de levadura. La presente también se relaciona y divulga toxinas denominadas AVP, que están modificadas desde la toxina Av3 obtenida de la anémona de mar; en la presente describimos los genes que codifican el polipéptido, así como diversas formulaciones y combinaciones; tanto de genes como de péptidos, útiles para el control de insectos. Reivindicación 1: Un AVP que tiene actividad insecticida contra una o más especies de insectos, donde dicho AVP tiene al menos una de las siguientes mutaciones: a) una mutación N-terminal que reemplaza a la arginina aminoterminal con un aminoácido lisina (R1K) en relación con la SEQ ID Nº 1, b) una deleción del aminoácido valina C-terminal en relación con la SEQ ID Nº 1.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862731387P | 2018-09-14 | 2018-09-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR114734A1 true AR114734A1 (es) | 2020-10-07 |
Family
ID=68073210
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP190102630A AR114734A1 (es) | 2018-09-14 | 2019-09-13 | POLIPÉPTIDOS INSECTICIDAS MUTANTES Av3 Y MÉTODOS PARA PRODUCIRLOS Y USARLOS |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20220048960A1 (es) |
| EP (1) | EP3850000A1 (es) |
| AR (1) | AR114734A1 (es) |
| BR (1) | BR112021004807A2 (es) |
| CA (1) | CA3112783A1 (es) |
| MX (1) | MX2021003021A (es) |
| UY (1) | UY38370A (es) |
| WO (1) | WO2020056315A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023524083A (ja) * | 2020-05-01 | 2023-06-08 | ヴェスタロン・コーポレーション | 殺虫剤の組み合わせ |
| EP4263580A2 (en) | 2020-12-21 | 2023-10-25 | Syngenta Crop Protection AG | Compositions comprising cyclotides and other insecticidal peptides and uses thereof |
| CN112724220B (zh) * | 2021-01-14 | 2023-03-14 | 海南医学院 | 海葵多肽Ap-TxⅠ及其制备方法与应用 |
| BR112023019825A2 (pt) * | 2021-04-01 | 2024-01-16 | Vestaron Corp | Polipeptídeos mutantes av3 para controle de pragas |
| CN113896780B (zh) * | 2021-08-31 | 2023-05-26 | 海南医学院 | 一种套膜海葵多肽毒素Ap-GR及其制备方法和应用 |
| CN116918770B (zh) * | 2023-06-09 | 2024-03-12 | 云南农业大学 | 一种人工扩繁龟瓢虫的方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4945050A (en) | 1984-11-13 | 1990-07-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
| AU642889B2 (en) | 1989-07-11 | 1993-11-04 | Biotechnology Research And Development Corporation | Aerosol beam microinjector |
| US5223408A (en) | 1991-07-11 | 1993-06-29 | Genentech, Inc. | Method for making variant secreted proteins with altered properties |
| US5743477A (en) | 1992-08-27 | 1998-04-28 | Dowelanco | Insecticidal proteins and method for plant protection |
| US6468523B1 (en) | 1998-11-02 | 2002-10-22 | Monsanto Technology Llc | Polypeptide compositions toxic to diabrotic insects, and methods of use |
| US6938976B2 (en) | 1999-06-16 | 2005-09-06 | Eastman Kodak Company | Printer and method therefor adapted to sense data uniquely associated with a consumable loaded into the printer |
| CA2396392C (en) | 1999-11-29 | 2015-04-21 | Midwest Oilseeds, Inc. | Methods and compositions for the introduction of molecules into cells |
| NZ629649A (en) * | 2012-03-09 | 2017-03-31 | Vestaron Corp | Toxic peptide production, peptide expression in plants and combinations of cysteine rich peptides |
-
2019
- 2019-09-13 BR BR112021004807-3A patent/BR112021004807A2/pt unknown
- 2019-09-13 AR ARP190102630A patent/AR114734A1/es not_active Application Discontinuation
- 2019-09-13 US US17/276,050 patent/US20220048960A1/en not_active Abandoned
- 2019-09-13 UY UY0001038370A patent/UY38370A/es not_active Application Discontinuation
- 2019-09-13 EP EP19779281.5A patent/EP3850000A1/en active Pending
- 2019-09-13 CA CA3112783A patent/CA3112783A1/en active Pending
- 2019-09-13 WO PCT/US2019/051093 patent/WO2020056315A1/en unknown
- 2019-09-13 MX MX2021003021A patent/MX2021003021A/es unknown
-
2024
- 2024-04-22 US US18/642,377 patent/US20240360185A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| UY38370A (es) | 2020-03-31 |
| US20240360185A1 (en) | 2024-10-31 |
| WO2020056315A4 (en) | 2020-05-28 |
| US20220048960A1 (en) | 2022-02-17 |
| CA3112783A1 (en) | 2020-03-19 |
| EP3850000A1 (en) | 2021-07-21 |
| MX2021003021A (es) | 2021-08-11 |
| BR112021004807A2 (pt) | 2021-06-08 |
| WO2020056315A1 (en) | 2020-03-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |