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AR085800A1 - Vacuna de rinitis equina - Google Patents

Vacuna de rinitis equina

Info

Publication number
AR085800A1
AR085800A1 ARP120100823A ARP120100823A AR085800A1 AR 085800 A1 AR085800 A1 AR 085800A1 AR P120100823 A ARP120100823 A AR P120100823A AR P120100823 A ARP120100823 A AR P120100823A AR 085800 A1 AR085800 A1 AR 085800A1
Authority
AR
Argentina
Prior art keywords
strain
identity
erav
equine
erab
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
ARP120100823A
Other languages
English (en)
Inventor
Phillip Wayne Hayes
Kristina J Hennessy
Laurent Viel
Andres Diaz-Mendez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Vetmedica de C V SA
Boehringer Ingelheim Vetmedica Inc
Original Assignee
Boehringer Ingelheim Vetmedica de C V SA
Boehringer Ingelheim Vetmedica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Vetmedica de C V SA, Boehringer Ingelheim Vetmedica Inc filed Critical Boehringer Ingelheim Vetmedica de C V SA
Publication of AR085800A1 publication Critical patent/AR085800A1/es
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/32011Picornaviridae
    • C12N2770/32034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/32011Picornaviridae
    • C12N2770/32711Rhinovirus
    • C12N2770/32734Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Composiciones inmunogénicas contra virus de rinitis equina, en particular virus de rinitis equina A y B y métodos para su uso y su preparación. Las composiciones inmunogénicas, en formas de realización alternativas, también incluyen otros agentes patógenos de equinos.Reivindicación 1: Una composición inmunogénica caracterizada porque comprende una o varias cepas de inactivados o vivos, atenuados el virus de rinitis equina A (ERAV) o virus de rinitis equina B (ERBV), a) en donde la cepa de ERAV o la cepa de ERAB, antes de la inactivación o atenuación, causa una enfermedad respiratoria detectable en al menos el 50% de caballos seronegativos expuestos a la cepa; y/o b) crecidos en cultivo celular a 106 TCID50/mL o más; y/o, c) cuando se usa como una vacuna en equinos en una dosis de 106 TCID50 o más da como resultado una titulación sérica de al menos 1:112; y/o d) en donde dicha cepa de ERAV comprende una secuencia genómica cuyo transcripto inverso tiene más del 95% de identidad con la SEQ ID Nº 2; y/o e) en donde dicho ERAV codifica una poliproteína con una secuencia de aminoácidos con más del 95% de identidad con la SEQ ID Nº 3; y/o f) en donde dicha cepa de ERBV comprende una secuencia genómica cuyo transcripto inverso tiene más del 95% de identidad con el transcripto inverso de la secuencia genómica de la cepa de ERAB que tiene número de acceso ATCC PTA-11829; y/o g) en donde dicha cepa de ERVB codifica una poliproteína con una secuencia de aminoácidos con más del 95% de identidad con la poliproteína codificada por el genoma de la cepa de ERAB que tiene número de acceso ATCC PTA-11829.
ARP120100823A 2011-03-14 2012-03-13 Vacuna de rinitis equina Pending AR085800A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161452390P 2011-03-14 2011-03-14
US201161510226P 2011-07-21 2011-07-21

Publications (1)

Publication Number Publication Date
AR085800A1 true AR085800A1 (es) 2013-10-30

Family

ID=45876924

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP120100823A Pending AR085800A1 (es) 2011-03-14 2012-03-13 Vacuna de rinitis equina

Country Status (12)

Country Link
US (1) US9187730B2 (es)
EP (2) EP2686012B1 (es)
AR (1) AR085800A1 (es)
AU (2) AU2012229192B2 (es)
BR (2) BR122019023542B1 (es)
CA (2) CA3018230A1 (es)
ES (2) ES2748555T3 (es)
MA (1) MA35303B1 (es)
MX (1) MX350718B (es)
NZ (1) NZ614147A (es)
TW (1) TW201300537A (es)
WO (1) WO2012125525A2 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2748555T3 (es) 2011-03-14 2020-03-17 Boehringer Ingelheim Animal Health Usa Inc Vacuna contra la rinitis equina
CA2967532A1 (en) 2014-11-24 2016-06-02 Intervet International B.V. Inactivated equine influenza virus vaccines
US10064930B2 (en) * 2015-01-16 2018-09-04 Boehringer-Ingelheim Vermedica, Inc. Immunogenic compositions and methods for pigeon fever
JP7354106B2 (ja) * 2017-12-04 2023-10-02 インターベット インターナショナル ベー. フェー. レプリコン粒子および油性アジュバントによるワクチン接種

Family Cites Families (31)

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WO2002072036A2 (en) 2001-03-12 2002-09-19 Yale University Compositions and methods comprising west nile virus polypeptides
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ES2748555T3 (es) 2011-03-14 2020-03-17 Boehringer Ingelheim Animal Health Usa Inc Vacuna contra la rinitis equina

Also Published As

Publication number Publication date
MA35303B1 (fr) 2014-08-01
AU2017201526B2 (en) 2019-07-18
AU2012229192B2 (en) 2017-04-20
BR122019023542B1 (pt) 2022-02-15
MX350718B (es) 2017-09-14
EP2686012A2 (en) 2014-01-22
AU2017201526A1 (en) 2017-03-30
EP2772266B1 (en) 2019-07-31
AU2017201526C1 (en) 2019-10-24
WO2012125525A2 (en) 2012-09-20
NZ708320A (en) 2016-08-26
EP2686012B1 (en) 2020-12-02
ES2842595T3 (es) 2021-07-14
ES2748555T3 (es) 2020-03-17
US20120237543A1 (en) 2012-09-20
NZ614147A (en) 2015-08-28
EP2772266A1 (en) 2014-09-03
US9187730B2 (en) 2015-11-17
TW201300537A (zh) 2013-01-01
CA2829226C (en) 2023-01-03
MX2013010125A (es) 2013-10-07
BR112013023354A2 (pt) 2016-12-06
BR112013023354B1 (pt) 2022-02-15
AU2012229192A1 (en) 2013-08-29
CA2829226A1 (en) 2012-09-20
CA3018230A1 (en) 2012-09-20
WO2012125525A3 (en) 2013-02-28

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