AR077402A2 - Secuencias de nucleotidos que intervienen en la fertilidad masculina en plantas y metodo de uso de las mismas - Google Patents
Secuencias de nucleotidos que intervienen en la fertilidad masculina en plantas y metodo de uso de las mismasInfo
- Publication number
- AR077402A2 AR077402A2 ARP100102457A ARP100102457A AR077402A2 AR 077402 A2 AR077402 A2 AR 077402A2 AR P100102457 A ARP100102457 A AR P100102457A AR P100102457 A ARP100102457 A AR P100102457A AR 077402 A2 AR077402 A2 AR 077402A2
- Authority
- AR
- Argentina
- Prior art keywords
- seq
- bases
- nucleic acid
- plant
- regulatory region
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8287—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for fertility modification, e.g. apomixis
- C12N15/8289—Male sterility
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8217—Gene switch
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8222—Developmentally regulated expression systems, tissue, organ specific, temporal or spatial regulation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8222—Developmentally regulated expression systems, tissue, organ specific, temporal or spatial regulation
- C12N15/823—Reproductive tissue-specific promoters
- C12N15/8231—Male-specific, e.g. anther, tapetum, pollen
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Reproductive Health (AREA)
- Botany (AREA)
- Pregnancy & Childbirth (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Reivindicacion 1: Un método para conmutar la fertilidad masculina de una planta, dicho método caracterizado porque comprende: introducir en el ADN de una planta un vector de expresion de un constructo que comprende una region reguladora heterologa con especificidad para tejidos masculinos de plantas heterologas ligada a un segundo ácido nucleico, donde dicha region reguladora se selecciona del grupo que consiste en: (i) SEQ ID NO:5; (ii) SEQ ID NO:6; (iii) bases 1 a 1088 de SEQ ID NO:7; (iv) bases 830 a 962 de SEQ ID NO:7; (v) bases 830 a 914 de SEQ ID NO:7; (vi) bases 917 a 962 de SEQ ID NO:7; (vii) bases 875 a 954 de SEQ ID NO:7; (viii) bases 935 a 954 de SEQ ID NO:7; (ix) bases 975 a 924 de SEQ ID NO:7; (x) bases 1 a 1005 de SEQ ID NO:7; y (xi) un fragmento de las bases 1 a 1088 de la SEQ ID NO:7; y donde dicha region reguladora esta ligada operativamente al segundo ácido nucleico que es una secuencia que reporta (ôreporterö) o una secuencia nucleotida heterologa, donde dicho segundo ácido nucleico es una secuencia nucleotida heterologa que está ligada operativamente a la region reguladora, de manera que la region reguladora regula la expresion del segundo ácido nucleico en el tejido masculino, y cultivar una planta en la cual el segundo ácido nucleico está incorporado en forma estable dentro del genoma de la planta y expresa el segundo ácido nucleico en el tejido masculino de la planta, donde el segundo ácido nucleico controla la fertilidad masculina de la planta.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67015300A | 2000-09-26 | 2000-09-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR077402A2 true AR077402A2 (es) | 2011-08-24 |
Family
ID=24689201
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP010104519A AR030961A1 (es) | 2000-09-26 | 2001-09-25 | Secuencias de nucleotidos que intervienen en la fertilidad masculina en plantas y metodo de uso de las mismas |
ARP100102457A AR077402A2 (es) | 2000-09-26 | 2010-07-07 | Secuencias de nucleotidos que intervienen en la fertilidad masculina en plantas y metodo de uso de las mismas |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP010104519A AR030961A1 (es) | 2000-09-26 | 2001-09-25 | Secuencias de nucleotidos que intervienen en la fertilidad masculina en plantas y metodo de uso de las mismas |
Country Status (10)
Country | Link |
---|---|
US (4) | US7098388B2 (es) |
EP (1) | EP1320618B1 (es) |
AR (2) | AR030961A1 (es) |
AT (1) | ATE548458T1 (es) |
AU (3) | AU9122801A (es) |
BR (1) | BR0114199A (es) |
CA (2) | CA2423480C (es) |
HU (1) | HU228694B1 (es) |
MX (1) | MXPA03002572A (es) |
WO (1) | WO2002026789A2 (es) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7612251B2 (en) | 2000-09-26 | 2009-11-03 | Pioneer Hi-Bred International, Inc. | Nucleotide sequences mediating male fertility and method of using same |
CA2423480C (en) * | 2000-09-26 | 2012-02-14 | Pioneer Hi-Bred International, Inc. | Nucleotide sequences mediating male fertility and method of using same |
US7517975B2 (en) | 2000-09-26 | 2009-04-14 | Pioneer Hi-Bred International, Inc. | Nucleotide sequences mediating male fertility and method of using same |
AU2011265403B2 (en) * | 2003-12-16 | 2012-07-05 | Pioneer Hi-Bred International, Inc. | Dominant gene suppression transgenes and methods of using same |
US20070169227A1 (en) | 2003-12-16 | 2007-07-19 | Pioneer Hi-Bred International Inc. | Dominant Gene Suppression Transgenes and Methods of Using Same |
CN104293912A (zh) * | 2003-12-16 | 2015-01-21 | 先锋高级育种国际公司 | 显性基因抑制性转基因及其使用方法 |
US20080244765A1 (en) * | 2004-12-16 | 2008-10-02 | Pioneer Hi-Bred International, Inc. | Methods and compositions for pollination disruption |
US7910802B2 (en) | 2007-08-03 | 2011-03-22 | Pioneer Hi-Bred International, Inc. | MSCA1 nucleotide sequences impacting plant male fertility and method of using same |
US7919676B2 (en) | 2007-08-03 | 2011-04-05 | Pioneer Hi-Bred International, Inc. | Msca1 nucleotide sequences impacting plant male fertility and method of using same |
US7915478B2 (en) | 2007-08-03 | 2011-03-29 | Pioneer Hi-Bred International, Inc. | Msca1 nucleotide sequences impacting plant male fertility and method of using same |
EP2257076B1 (en) * | 2009-05-28 | 2015-02-25 | Advanced Digital Broadcast S.A. | Video data signal, system and method for controlling shutter glasses |
WO2013138358A1 (en) | 2012-03-13 | 2013-09-19 | Pioneer Hi-Bred International, Inc. | Genetic reduction of male fertility in plants |
WO2013138309A1 (en) | 2012-03-13 | 2013-09-19 | Pioneer Hi-Bred International, Inc. | Genetic reduction of male fertility in plants |
WO2014160122A1 (en) | 2013-03-14 | 2014-10-02 | Pioneer Hi-Bred International, Inc. | Maize stress related transcription factor 18 and uses thereof |
CA2903555A1 (en) | 2013-03-15 | 2014-09-18 | Pioneer Hi-Bred International, Inc. | Compositions and methods of use of acc oxidase polynucleotides and polypeptides |
US20150082478A1 (en) | 2013-08-22 | 2015-03-19 | E I Du Pont De Nemours And Company | Plant genome modification using guide rna/cas endonuclease systems and methods of use |
CN106687594A (zh) | 2014-07-11 | 2017-05-17 | 纳幕尔杜邦公司 | 用于产生对草甘膦除草剂具有抗性的植物的组合物和方法 |
US20170369902A1 (en) | 2014-12-16 | 2017-12-28 | Pioneer Hi-Bred International, Inc. | Restoration of male fertility in wheat |
CA2985991A1 (en) | 2015-02-25 | 2016-09-01 | Andrew Mark CIGAN | Composition and methods for regulated expression of a guide rna/cas endonuclease complex |
CA2985079A1 (en) | 2015-05-15 | 2016-11-24 | Pioneer Hi-Bred International, Inc. | Rapid characterization of cas endonuclease systems, pam sequences and guide rna elements |
EP3365440B1 (en) | 2015-10-20 | 2022-09-14 | Pioneer Hi-Bred International, Inc. | Restoring function to a non-functional gene product via guided cas systems and methods of use |
BR112018007796A2 (pt) | 2015-11-06 | 2018-10-30 | Du Pont | plantas de soja, partes de plantas de soja ou sementes de soja, método para selecionar uma célula de soja, métodos de seleção de uma célula de soja e de produção de um locus e molécula de ácido nucleico |
EP3426780A1 (en) | 2016-03-11 | 2019-01-16 | Pioneer Hi-Bred International, Inc. | Novel cas9 systems and methods of use |
US20200332305A1 (en) | 2016-06-14 | 2020-10-22 | Pioneer Hi-Bred International, Inc. | Use of cpfi endonuclease for plant genome modifications |
WO2017222773A1 (en) | 2016-06-20 | 2017-12-28 | Pioneer Hi-Bred International, Inc. | Novel cas systems and methods of use |
WO2018202800A1 (en) | 2017-05-03 | 2018-11-08 | Kws Saat Se | Use of crispr-cas endonucleases for plant genome engineering |
US11697822B2 (en) | 2017-08-29 | 2023-07-11 | KWS SAAT SE & Co. KGaA | Blue aleurone and other segregation systems |
CN111465321B (zh) | 2017-10-13 | 2022-12-06 | 先锋国际良种公司 | 用于植物细胞的细胞重编程的系统和方法 |
WO2020214986A1 (en) | 2019-04-18 | 2020-10-22 | Pioneer Hi-Bred International, Inc. | Embryogenesis factors for cellular reprogramming of a plant cell |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5608142A (en) | 1986-12-03 | 1997-03-04 | Agracetus, Inc. | Insecticidal cotton plants |
US5689041A (en) * | 1989-08-10 | 1997-11-18 | Plant Gentic Systems N.V. | Plants modified with barstar for fertility restoration |
US5432068A (en) * | 1990-06-12 | 1995-07-11 | Pioneer Hi-Bred International, Inc. | Control of male fertility using externally inducible promoter sequences |
US5478369A (en) | 1990-06-12 | 1995-12-26 | Pioneer Hi-Bred International, Inc. | Nucleotide sequences mediating male fertility and method of using same |
US5656531A (en) | 1993-12-10 | 1997-08-12 | Micron Technology, Inc. | Method to form hemi-spherical grain (HSG) silicon from amorphous silicon |
US5837850A (en) * | 1994-04-21 | 1998-11-17 | Pioneer Hi-Bred International, Inc. | Regulatory element conferring tapetum specificity |
US5470359A (en) * | 1994-04-21 | 1995-11-28 | Pioneer Hi-Bred Internation, Inc. | Regulatory element conferring tapetum specificity |
EP0787189B1 (en) * | 1994-10-28 | 2005-06-01 | Pioneer Hi-Bred International, Inc. | Nucleotide sequences mediating male fertility and method of using same |
US5795753A (en) * | 1994-12-08 | 1998-08-18 | Pioneer Hi-Bred International Inc. | Reversible nuclear genetic system for male sterility in transgenic plants |
US5789166A (en) * | 1995-12-08 | 1998-08-04 | Stratagene | Circular site-directed mutagenesis |
US6037523A (en) * | 1997-06-23 | 2000-03-14 | Pioneer Hi-Bred International | Male tissue-preferred regulatory region and method of using same |
AU7975598A (en) | 1997-06-23 | 1999-01-04 | Colgate-Palmolive Company, The | Microemulsion all purpose liquid cleaning compositions |
IL131095A0 (en) | 1999-07-25 | 2001-01-28 | Israel State | A method for obtaining 100% male sterile plants to serve as the female parent in hybrid seeds production |
US7612251B2 (en) * | 2000-09-26 | 2009-11-03 | Pioneer Hi-Bred International, Inc. | Nucleotide sequences mediating male fertility and method of using same |
CA2423480C (en) * | 2000-09-26 | 2012-02-14 | Pioneer Hi-Bred International, Inc. | Nucleotide sequences mediating male fertility and method of using same |
US7517975B2 (en) * | 2000-09-26 | 2009-04-14 | Pioneer Hi-Bred International, Inc. | Nucleotide sequences mediating male fertility and method of using same |
US6878531B1 (en) * | 2003-11-10 | 2005-04-12 | Medical College Of Georgia Research Institute | Method for multiple site-directed mutagenesis |
US7750207B2 (en) * | 2004-09-01 | 2010-07-06 | Monsanto Technology Llc | Zea mays ribulose bisphosphate carboxylase activase promoter |
US20060141495A1 (en) * | 2004-09-01 | 2006-06-29 | Kunsheng Wu | Polymorphic markers and methods of genotyping corn |
US7919676B2 (en) * | 2007-08-03 | 2011-04-05 | Pioneer Hi-Bred International, Inc. | Msca1 nucleotide sequences impacting plant male fertility and method of using same |
-
2001
- 2001-09-25 CA CA2423480A patent/CA2423480C/en not_active Expired - Fee Related
- 2001-09-25 WO PCT/US2001/029886 patent/WO2002026789A2/en active Application Filing
- 2001-09-25 AT AT01971332T patent/ATE548458T1/de active
- 2001-09-25 AU AU9122801A patent/AU9122801A/xx active Pending
- 2001-09-25 CA CA2760906A patent/CA2760906C/en not_active Expired - Fee Related
- 2001-09-25 EP EP01971332A patent/EP1320618B1/en not_active Expired - Lifetime
- 2001-09-25 BR BR0114199-6A patent/BR0114199A/pt not_active Application Discontinuation
- 2001-09-25 AU AU2001291228A patent/AU2001291228B2/en not_active Ceased
- 2001-09-25 MX MXPA03002572A patent/MXPA03002572A/es active IP Right Grant
- 2001-09-25 AR ARP010104519A patent/AR030961A1/es not_active Application Discontinuation
- 2001-09-25 HU HU0501107A patent/HU228694B1/hu unknown
- 2001-12-14 US US10/021,657 patent/US7098388B2/en not_active Expired - Lifetime
-
2003
- 2003-04-11 US US10/412,000 patent/US7151205B2/en not_active Expired - Fee Related
-
2006
- 2006-05-11 US US11/432,758 patent/US20060212971A1/en not_active Abandoned
-
2007
- 2007-03-12 AU AU2007201072A patent/AU2007201072C1/en not_active Ceased
-
2008
- 2008-01-02 US US11/968,557 patent/US20080134362A1/en not_active Abandoned
-
2010
- 2010-07-07 AR ARP100102457A patent/AR077402A2/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2002026789A2 (en) | 2002-04-04 |
EP1320618A2 (en) | 2003-06-25 |
US7098388B2 (en) | 2006-08-29 |
CA2760906C (en) | 2016-11-29 |
AU2007201072C1 (en) | 2010-02-11 |
HUP0501107A2 (en) | 2006-06-28 |
AU2001291228B2 (en) | 2007-01-11 |
WO2002026789A3 (en) | 2003-02-13 |
US20060212971A1 (en) | 2006-09-21 |
AU2007201072B2 (en) | 2009-09-17 |
CA2423480A1 (en) | 2002-04-04 |
AR030961A1 (es) | 2003-09-03 |
ATE548458T1 (de) | 2012-03-15 |
EP1320618B1 (en) | 2012-03-07 |
US20080134362A1 (en) | 2008-06-05 |
WO2002026789A9 (en) | 2003-07-03 |
CA2423480C (en) | 2012-02-14 |
CA2760906A1 (en) | 2002-04-04 |
AU9122801A (en) | 2002-04-08 |
BR0114199A (pt) | 2006-01-31 |
US20020083483A1 (en) | 2002-06-27 |
US20030182689A1 (en) | 2003-09-25 |
HU228694B1 (en) | 2013-05-28 |
US7151205B2 (en) | 2006-12-19 |
AU2007201072A1 (en) | 2007-03-29 |
MXPA03002572A (es) | 2004-08-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AR077402A2 (es) | Secuencias de nucleotidos que intervienen en la fertilidad masculina en plantas y metodo de uso de las mismas | |
De Lange et al. | Structure and variability of human chromosome ends | |
KR102207728B1 (ko) | 올리고뉴클레오타이드 매개 유전자 보수를 사용한 표적화된 유전자 변형의 효율을 증가시키기 위한 방법 및 조성물 | |
Visvader et al. | Eleven new sequence variants of citrus exocortis viroid and the correlation of sequence with pathogenicity | |
KR102151065B1 (ko) | 동물 배아의 염기 교정용 조성물 및 염기 교정 방법 | |
ATE222289T1 (de) | Rekombinatorische klonierung in vitro unter verwendung genmanipulierter rekombinationsorte | |
KR20200103769A (ko) | 연장된 단일 가이드 rna 및 그 용도 | |
CN107922931A (zh) | 热稳定的Cas9核酸酶 | |
AR055169A1 (es) | Metodos para el control genetico de infestaciones de insectos en plantas y composiciones para los mismos | |
AR036209A1 (es) | Plantas de algodon tolerantes a herbicidas y metodos para producir e identificar las mismas | |
DE69833457D1 (de) | Neuartige methode zur integration von fremd-dna ins eukaryotische genom | |
DE69430993D1 (de) | Kontrollierte expression transgener konstrukte in pflanzenplastiden | |
AR044724A1 (es) | Promotores del virus de la rizadura amarilla del cestrum | |
DE602004031041D1 (de) | In pflanzenplastiden funktionsfähiger promotor | |
Scutt et al. | Laser isolation of plant sex chromosomes: studies on the DNA composition of the X and Y sex chromosomes of Silene latifolia | |
ATE399858T1 (de) | Blütenorgan-spezifische promotersequenzen | |
RU2008129105A (ru) | Конститутивные промоторы растений | |
CN103459596A (zh) | 靶向改变dna | |
CN106754949B (zh) | 猪肌抑素基因编辑位点864-883及其应用 | |
KR930019822A (ko) | 가광견병 바이러스 폴리뉴클레오티드 및 바이러스-내성 진핵세포의 제조를 위한 그의 용도 | |
Morgan et al. | Variations in transcriptional activity of rDNA spacer promoters | |
JP2020508693A (ja) | C2c1エンドヌクレアーゼを含むゲノム編集用組成物およびこれを用いたゲノム編集方法 | |
Monroe et al. | Extent of CpG methylation is not proportional to the in vivo spontaneous mutation frequency at transgenic loci in Big Blue™ rodents | |
AR129714A1 (es) | Edición de base diversificadora | |
AUPS333902A0 (en) | Method of producing plants having enhanced transpiration efficiency and plants produced therefrom i |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant, registration | ||
FD | Application declared void or lapsed, e.g., due to non-payment of fee |