AR063619A1 - Dispositivos y metodos para la administraicion de un farmaco oftalmico - Google Patents
Dispositivos y metodos para la administraicion de un farmaco oftalmicoInfo
- Publication number
- AR063619A1 AR063619A1 ARP070104978A ARP070104978A AR063619A1 AR 063619 A1 AR063619 A1 AR 063619A1 AR P070104978 A ARP070104978 A AR P070104978A AR P070104978 A ARP070104978 A AR P070104978A AR 063619 A1 AR063619 A1 AR 063619A1
- Authority
- AR
- Argentina
- Prior art keywords
- matrix
- drug
- subject
- contact
- eye
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M35/00—Devices for applying media, e.g. remedies, on the human body
- A61M35/003—Portable hand-held applicators having means for dispensing or spreading integral media
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Dispositivos de administración oftálmica, que comprenden un cuerpo que posee un extremo proximal y un extremo distal, en donde el cuerpo incluye una matriz de elastómero de estireno y un fármaco en contacto con la matriz. También, se describen métodos para tratar o prevenir una enfermedad ocular en un sujeto, que comprende poner en contacto un ojo del sujeto con un dispositivo de administración de fármacos oftálmicos que comprende un extremo proximal y un extremo distal, en donde el cuerpo comprende una matriz de elastómero de estireno y un fármaco en contacto con la matriz, en donde la liberación del fármaco desde el dispositivo se produce luego del contacto del dispositivo con el ojo del sujeto. Reivindicación 1: Un dispositivo de administración de fármaco oftálmico que comprende: un cuerpo configurado para insertarse en un sujeto en proximidad a un ojo del sujeto, en donde el cuerpo incluye una matriz de elastómero de estireno; y un fármaco en contacto con la matriz.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US85814306P | 2006-12-18 | 2006-12-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR063619A1 true AR063619A1 (es) | 2009-02-04 |
Family
ID=39265276
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP070104978A AR063619A1 (es) | 2006-12-18 | 2007-11-08 | Dispositivos y metodos para la administraicion de un farmaco oftalmico |
Country Status (13)
Country | Link |
---|---|
US (2) | US20080145406A1 (es) |
EP (1) | EP2091481A2 (es) |
JP (1) | JP5323720B2 (es) |
KR (1) | KR20090098870A (es) |
CN (2) | CN103622778A (es) |
AR (1) | AR063619A1 (es) |
AU (1) | AU2007334248B2 (es) |
BR (1) | BRPI0720431A2 (es) |
CA (1) | CA2670944A1 (es) |
MX (1) | MX2009006146A (es) |
TW (1) | TW200829293A (es) |
WO (1) | WO2008076544A2 (es) |
ZA (1) | ZA200903649B (es) |
Families Citing this family (59)
Publication number | Priority date | Publication date | Assignee | Title |
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US7431710B2 (en) | 2002-04-08 | 2008-10-07 | Glaukos Corporation | Ocular implants with anchors and methods thereof |
WO2005020907A2 (en) | 2003-08-26 | 2005-03-10 | Vista Scientific | Ocular drug delivery device |
WO2005020972A2 (en) * | 2003-08-27 | 2005-03-10 | (Osi) Eyetech, Inc. | Combination therapy for the treatment of ocular neovascular disorders |
WO2009064834A2 (en) * | 2007-11-13 | 2009-05-22 | Maskin Steven L | Meibomian gland intraductal diagnostic and treatment methods and related apparatus |
US9510844B2 (en) | 2007-11-13 | 2016-12-06 | Mgd Innovations, Llc | Gland or duct diagnostic and treatment methods and related apparatus |
US10022558B1 (en) | 2008-01-07 | 2018-07-17 | Salutaris Medical Devices, Inc. | Methods and devices for minimally-invasive delivery of radiation to the eye |
US9873001B2 (en) | 2008-01-07 | 2018-01-23 | Salutaris Medical Devices, Inc. | Methods and devices for minimally-invasive delivery of radiation to the eye |
US10064819B2 (en) | 2008-05-12 | 2018-09-04 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
WO2009140246A2 (en) | 2008-05-12 | 2009-11-19 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
US9877973B2 (en) | 2008-05-12 | 2018-01-30 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
US9095404B2 (en) | 2008-05-12 | 2015-08-04 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
CN102105118A (zh) * | 2008-06-24 | 2011-06-22 | Qlt栓塞输送公司 | 青光眼的联合治疗 |
US8623395B2 (en) | 2010-01-29 | 2014-01-07 | Forsight Vision4, Inc. | Implantable therapeutic device |
CN104887389B (zh) | 2009-01-29 | 2017-06-23 | 弗赛特影像4股份有限公司 | 后段给药 |
WO2010101758A1 (en) * | 2009-03-03 | 2010-09-10 | Alcon Research, Ltd. | Peri-corneal drug delivery device |
US10206813B2 (en) | 2009-05-18 | 2019-02-19 | Dose Medical Corporation | Implants with controlled drug delivery features and methods of using same |
WO2010141729A1 (en) | 2009-06-03 | 2010-12-09 | Forsight Labs, Llc | Anterior segment drug delivery |
WO2013022801A1 (en) | 2011-08-05 | 2013-02-14 | Forsight Vision4, Inc. | Small molecule delivery with implantable therapeutic device |
AU2011285548B2 (en) | 2010-08-05 | 2014-02-06 | Forsight Vision4, Inc. | Combined drug delivery methods and apparatus |
JP5907966B2 (ja) | 2010-08-05 | 2016-04-26 | フォーサイト・ビジョン フォー・インコーポレーテッド | 埋め込み型治療デバイス |
EP3861969A1 (en) | 2010-08-05 | 2021-08-11 | ForSight Vision4, Inc. | Injector apparatus for drug delivery |
AU2011329656B2 (en) | 2010-11-19 | 2017-01-05 | Forsight Vision4, Inc. | Therapeutic agent formulations for implanted devices |
WO2012092510A2 (en) * | 2010-12-29 | 2012-07-05 | I Therapeutics, Llc | Ocular drug delivery system |
US10245178B1 (en) | 2011-06-07 | 2019-04-02 | Glaukos Corporation | Anterior chamber drug-eluting ocular implant |
WO2013003620A2 (en) | 2011-06-28 | 2013-01-03 | Forsight Vision4, Inc. | Diagnostic methods and apparatus |
WO2013040238A2 (en) | 2011-09-13 | 2013-03-21 | Vista Scientific Llc | Sustained release ocular drug delivery devices and methods of manufacture |
WO2013040426A2 (en) | 2011-09-14 | 2013-03-21 | Forsight Labs, Llc | Ocular insert apparatus and methods |
RS61758B1 (sr) | 2011-09-16 | 2021-05-31 | Forsight Vision4 Inc | Aparati za razmenu tečnosti |
WO2013116061A1 (en) | 2012-02-03 | 2013-08-08 | Forsight Vision4, Inc. | Insertion and removal methods and apparatus for therapeutic devices |
US9642742B2 (en) | 2012-10-02 | 2017-05-09 | Harold D. Mansfield | Eye drop applicator and drop transfer method |
DK2911623T3 (da) | 2012-10-26 | 2019-10-28 | Forsight Vision5 Inc | Oftalmisk system til langvarig frigivelse af lægemiddel til øjet |
HUE048687T2 (hu) | 2013-02-18 | 2020-08-28 | Vegenics Pty Ltd | Ligandum kötõ molekulák és alkalmazásaik |
WO2014152959A1 (en) | 2013-03-14 | 2014-09-25 | Forsight Vision4, Inc. | Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant |
JP6385423B2 (ja) | 2013-03-28 | 2018-09-05 | フォーサイト・ビジョン フォー・インコーポレーテッド | 治療物質送達用の眼移植片 |
CN105431204A (zh) | 2013-07-12 | 2016-03-23 | 奥普索特克公司 | 用于治疗或预防眼科病的方法 |
AU2015266850B2 (en) | 2014-05-29 | 2019-12-05 | Glaukos Corporation | Implants with controlled drug delivery features and methods of using same |
US10258503B2 (en) | 2014-07-15 | 2019-04-16 | Forsight Vision4, Inc. | Ocular implant delivery device and method |
RU2017105844A (ru) | 2014-08-08 | 2018-09-11 | Форсайт Вижн4, Инк. | Стабильные и растворимые составы ингибиторов рецепторных тирозинкиназ и способы их получения |
JP7026507B2 (ja) * | 2014-09-06 | 2022-02-28 | インテグラル バイオシステムズ エルエルシー | 眼において薬物徐放を達成する方法及び生体適合性組成物 |
KR20170106298A (ko) | 2014-11-10 | 2017-09-20 | 포사이트 비젼4, 인크. | 확장 가능한 약물 전달 장치 및 이용 방법 |
WO2016168141A1 (en) | 2015-04-13 | 2016-10-20 | Forsight Vision5, Inc. | Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent |
US10010502B2 (en) | 2015-05-19 | 2018-07-03 | Amorphex Therapeutics Llc | Device that delivers a sustained low-dose of a myopia-suppressing drug, while preserving pupillary function and accommodation |
US11925578B2 (en) | 2015-09-02 | 2024-03-12 | Glaukos Corporation | Drug delivery implants with bi-directional delivery capacity |
WO2017053885A1 (en) | 2015-09-25 | 2017-03-30 | Glaukos Corporation | Punctal implants with controlled drug delivery features and methods of using same |
US11432959B2 (en) | 2015-11-20 | 2022-09-06 | Forsight Vision4, Inc. | Porous structures for extended release drug delivery devices |
ES2837524T3 (es) | 2016-04-05 | 2021-06-30 | Forsight Vision4 Inc | Dispositivos de administración de fármacos oculares implantables |
AU2017252294B2 (en) | 2016-04-20 | 2021-12-02 | Dose Medical Corporation | Bioresorbable ocular drug delivery device |
USD814638S1 (en) | 2016-05-11 | 2018-04-03 | Salutaris Medical Devices, Inc. | Brachytherapy device |
USD814637S1 (en) | 2016-05-11 | 2018-04-03 | Salutaris Medical Devices, Inc. | Brachytherapy device |
USD815285S1 (en) | 2016-05-11 | 2018-04-10 | Salutaris Medical Devices, Inc. | Brachytherapy device |
USD808529S1 (en) | 2016-08-31 | 2018-01-23 | Salutaris Medical Devices, Inc. | Holder for a brachytherapy device |
USD808528S1 (en) | 2016-08-31 | 2018-01-23 | Salutaris Medical Devices, Inc. | Holder for a brachytherapy device |
US10603210B1 (en) | 2017-02-02 | 2020-03-31 | Mgd Innovations, Llc | Meibomian gland probing with blood product injection |
EP3713528A1 (en) | 2017-11-21 | 2020-09-30 | ForSight Vision4, Inc. | Fluid exchange apparatus for expandable port delivery system and methods of use |
US11690806B2 (en) | 2018-05-24 | 2023-07-04 | Celanese Eva Performance Polymers Llc | Implantable device for sustained release of a macromolecular drug compound |
CA3087238A1 (en) | 2018-05-24 | 2019-11-28 | Celanese EVA Performance Polymers Corporation | Implantable device for sustained release of a macromolecular drug compound |
US11689849B2 (en) | 2018-05-24 | 2023-06-27 | Nureva, Inc. | Method, apparatus and computer-readable media to manage semi-constant (persistent) sound sources in microphone pickup/focus zones |
USD1033637S1 (en) | 2022-01-24 | 2024-07-02 | Forsight Vision4, Inc. | Fluid exchange device |
CN114652826B (zh) * | 2022-01-24 | 2022-10-14 | 景泽生物医药(合肥)有限公司 | 抗egfr抗体的用途 |
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AR206692A1 (es) * | 1972-12-27 | 1976-08-13 | Alza Corp | Agente dispensador de liberacion sostenida de substancias activas |
US5178635A (en) * | 1992-05-04 | 1993-01-12 | Allergan, Inc. | Method for determining amount of medication in an implantable device |
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ATE547080T1 (de) * | 2000-08-30 | 2012-03-15 | Univ Johns Hopkins | Vorrichtungen zur intraokularen arzneimittelabgabe |
EP1404295B1 (en) * | 2001-01-03 | 2007-10-10 | Bausch & Lomb Incorporated | Sustained release drug delivery devices with coated drug cores |
TWI231759B (en) * | 2001-06-27 | 2005-05-01 | Alcon Inc | Olopatadine formulations for topical administration |
JP2005535691A (ja) * | 2002-08-05 | 2005-11-24 | アルコン,インコーポレイテッド | 加齢性黄斑変性を有する患者における視力の保護のための酢酸アネコルタブの使用 |
US20040219198A1 (en) * | 2003-05-01 | 2004-11-04 | 3M Innovative Properties Company | Transdermal drug delivery device with multilayer backing |
US7794498B2 (en) * | 2003-12-05 | 2010-09-14 | Innolene Llc | Ocular lens |
WO2005055972A2 (en) * | 2003-12-09 | 2005-06-23 | Nanon A/S | A drug delivery device and a method of producing it |
US20050181015A1 (en) * | 2004-02-12 | 2005-08-18 | Sheng-Ping (Samuel) Zhong | Layered silicate nanoparticles for controlled delivery of therapeutic agents from medical articles |
EP1740236A2 (en) * | 2004-04-06 | 2007-01-10 | SurModics, Inc. | Coating compositions for bioactive agents |
TW200640443A (en) * | 2005-02-23 | 2006-12-01 | Alcon Inc | Methods for treating ocular angiogenesis, retinal edema, retinal ischemia, and diabetic retinopathy using selective RTK inhibitors |
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US10029034B2 (en) * | 2005-12-15 | 2018-07-24 | CARDINAL HEALTH SWITZERLAND 515 GmbH | Drug-eluting articles with improved drug release profiles |
-
2007
- 2007-11-08 US US11/936,842 patent/US20080145406A1/en not_active Abandoned
- 2007-11-08 AU AU2007334248A patent/AU2007334248B2/en not_active Ceased
- 2007-11-08 CN CN201310628215.3A patent/CN103622778A/zh active Pending
- 2007-11-08 KR KR1020097014324A patent/KR20090098870A/ko active IP Right Grant
- 2007-11-08 JP JP2009542994A patent/JP5323720B2/ja not_active Expired - Fee Related
- 2007-11-08 MX MX2009006146A patent/MX2009006146A/es not_active Application Discontinuation
- 2007-11-08 AR ARP070104978A patent/AR063619A1/es not_active Application Discontinuation
- 2007-11-08 BR BRPI0720431-0A patent/BRPI0720431A2/pt not_active IP Right Cessation
- 2007-11-08 WO PCT/US2007/084009 patent/WO2008076544A2/en active Application Filing
- 2007-11-08 ZA ZA200903649A patent/ZA200903649B/xx unknown
- 2007-11-08 TW TW096142198A patent/TW200829293A/zh unknown
- 2007-11-08 EP EP07864078A patent/EP2091481A2/en not_active Withdrawn
- 2007-11-08 CN CNA2007800456351A patent/CN101563051A/zh active Pending
- 2007-11-08 CA CA002670944A patent/CA2670944A1/en not_active Abandoned
-
2010
- 2010-05-07 US US12/775,551 patent/US20100266664A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2007334248B2 (en) | 2013-06-27 |
ZA200903649B (en) | 2010-08-25 |
CN101563051A (zh) | 2009-10-21 |
WO2008076544A3 (en) | 2008-08-28 |
WO2008076544A2 (en) | 2008-06-26 |
KR20090098870A (ko) | 2009-09-17 |
CA2670944A1 (en) | 2008-06-26 |
TW200829293A (en) | 2008-07-16 |
BRPI0720431A2 (pt) | 2013-12-31 |
JP2010513542A (ja) | 2010-04-30 |
JP5323720B2 (ja) | 2013-10-23 |
MX2009006146A (es) | 2009-06-19 |
AU2007334248A1 (en) | 2008-06-26 |
EP2091481A2 (en) | 2009-08-26 |
CN103622778A (zh) | 2014-03-12 |
US20100266664A1 (en) | 2010-10-21 |
US20080145406A1 (en) | 2008-06-19 |
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