AR038000A1 - Compuesto derivado de tien[2,3-d]pirimidin-2,4(1h,3h)-diona, composicion farmaceutica, proceso para su preparacion y su uso en la fabricacion de un medicamento - Google Patents
Compuesto derivado de tien[2,3-d]pirimidin-2,4(1h,3h)-diona, composicion farmaceutica, proceso para su preparacion y su uso en la fabricacion de un medicamentoInfo
- Publication number
- AR038000A1 AR038000A1 ARP020102842A ARP020102842A AR038000A1 AR 038000 A1 AR038000 A1 AR 038000A1 AR P020102842 A ARP020102842 A AR P020102842A AR P020102842 A ARP020102842 A AR P020102842A AR 038000 A1 AR038000 A1 AR 038000A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- optionally substituted
- hydrogen atom
- nitrogen
- ring
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Communicable Diseases (AREA)
- Transplantation (AREA)
- Biomedical Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- AIDS & HIV (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
Abstract
Compuesto derivado de tien[2,3-d]pirimidin-2,4(1H,3H)-diona de fórmula (1); donde: R1 y R2 representan cada uno independientemente un alquilo C1-6, alquenilo C3-6, cicloalquil C3-5-alquilo C1-3 o cicloalquilo C3-6; cada uno puede ser opcionalmente sustituido por entre 1 y 3 átomos de halógeno; R3 es isoxazolidin-2-ilcarbonilo o tetrahidroisoxazin-2-ilcarbonilo donde cada anillo es opcionalmente sustituido por un grupo hidroxi; Q es -CO- o -C(R4)(R5)- (donde R4 es un átomo de hidrógeno o alquilo C1-4 y R5 es un átomo de hidrógeno o un grupo hidroxi); Ar es un sistema de anillos aromático de 5 a 10 miembros donde hasta 4 átomos del anillo pueden ser heteroátomos seleccionados independientemente entre nitrógeno, oxígeno y azufre, estando el sistema de anillos opcionalmente sustituido por uno o más sustituyentes seleccionados independientemente entre alquilo C1-4 ( opcionalmente sustituido por 1, 2 o 3 grupos hidroxi), alcoxi C1-4, halógeno, haloalquilo, dihaloquilo, trihaloquilo, alcoxi C1-4-alquilo C1-4, alquiltio C1-4, alcoxicarbonilo C1-4, alcanoilo C2-4, oxo, tioxo, nitro, ciano, -N(R6)R7 y -(CH2)pN(R8)R9, hidroxi, alquilsulfonilo C1-4, alquilsulfinilo C1-4, carbamoilo, alquilcarbamoilo C1-4, di-(alquil C1-4)carbamoilo, carboxi, o un anillo aromático de 5 o 6 miembros que contiene hasta 4 heteroátomos seleccionados independientemente entre nitrógeno, oxígeno y azufre; p es entre 1 y 4; R6 y R7 representan cada uno independiente un átomo de hidrógeno, alcanoilo C1-4 o alquilo C1-4, o junto con el átomo de nitrógeno al cual están unidos forman un anillo heterocíclico saturado de 5 a 7 miembros; R8 y R9 representan cada uno independientemente un átomo de hidrógeno, alcanoilo C1-4 o alquilo C1-4, o junto con el átomo de nitrógeno al cual están unidos forman un anillo heterocíclico saturado de 5 a 7 miembros; o una sal aceptable para uso farmacéutico o profármaco del mismo. También se relaciona con métodos de preparación, composiciones farmacéuticas que los contienen y usos del mismo en la fabricación de un medicamento particularmente útil en la modulación de una enfermedad autoinmune.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0118479.5A GB0118479D0 (en) | 2001-07-28 | 2001-07-28 | Novel compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
AR038000A1 true AR038000A1 (es) | 2004-12-22 |
Family
ID=9919407
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP020102842A AR038000A1 (es) | 2001-07-28 | 2002-07-26 | Compuesto derivado de tien[2,3-d]pirimidin-2,4(1h,3h)-diona, composicion farmaceutica, proceso para su preparacion y su uso en la fabricacion de un medicamento |
Country Status (25)
Country | Link |
---|---|
US (2) | US7384950B2 (es) |
EP (1) | EP1414825B9 (es) |
JP (1) | JP4456364B2 (es) |
KR (1) | KR100897469B1 (es) |
CN (1) | CN1324033C (es) |
AR (1) | AR038000A1 (es) |
AT (1) | ATE374204T1 (es) |
AU (1) | AU2002319469B2 (es) |
BR (1) | BR0211262A (es) |
CA (1) | CA2453274A1 (es) |
DE (1) | DE60222671T2 (es) |
ES (1) | ES2292784T3 (es) |
GB (1) | GB0118479D0 (es) |
HK (1) | HK1065785A1 (es) |
HU (1) | HUP0402336A3 (es) |
IL (2) | IL159785A0 (es) |
IS (1) | IS2598B (es) |
MX (1) | MXPA04000677A (es) |
MY (1) | MY138145A (es) |
NO (1) | NO328713B1 (es) |
NZ (1) | NZ530495A (es) |
PL (1) | PL211351B1 (es) |
RU (1) | RU2294937C9 (es) |
WO (1) | WO2003011868A1 (es) |
ZA (1) | ZA200400574B (es) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9801399D0 (sv) | 1998-04-21 | 1998-04-21 | Astra Pharma Prod | Method and apparatus for filling containers |
GB0117583D0 (en) * | 2001-07-19 | 2001-09-12 | Astrazeneca Ab | Novel compounds |
GB0118479D0 (en) * | 2001-07-28 | 2001-09-19 | Astrazeneca Ab | Novel compounds |
US7655658B2 (en) | 2001-08-10 | 2010-02-02 | Palatin Technologies, Inc. | Thieno [2,3-D]pyrimidine-2,4-dione melanocortin-specific compounds |
US7456184B2 (en) | 2003-05-01 | 2008-11-25 | Palatin Technologies Inc. | Melanocortin receptor-specific compounds |
US7718802B2 (en) | 2001-08-10 | 2010-05-18 | Palatin Technologies, Inc. | Substituted melanocortin receptor-specific piperazine compounds |
JP2005504043A (ja) | 2001-08-10 | 2005-02-10 | パラチン テクノロジーズ インク. | 生物学的に活性な金属ペプチド類のペプチド模倣体類 |
US7732451B2 (en) | 2001-08-10 | 2010-06-08 | Palatin Technologies, Inc. | Naphthalene-containing melanocortin receptor-specific small molecule |
CA2494421A1 (en) | 2002-08-06 | 2004-02-12 | Astrazeneca Ab | Condensed pyridines and pyrimidines with tie2 (tek) activity |
US6890923B2 (en) * | 2002-12-16 | 2005-05-10 | Astrazeneca Ab | Compounds |
SE0300119D0 (sv) * | 2003-01-17 | 2003-01-17 | Astrazeneca Ab | Novel compounds |
SE0300120D0 (sv) * | 2003-01-17 | 2003-01-17 | Astrazeneca Ab | Novel compounds |
BRPI0406782A (pt) | 2003-01-17 | 2006-01-17 | Astrazeneca Ab | Derivados de tieno-piridazinonas e seu uso na modulação de doenças autoimunes |
MXPA05009722A (es) * | 2003-03-10 | 2006-03-09 | Schering Corp | Inhibidores heterociclicos de cinasa: metodos de uso y sintesis. |
US7968548B2 (en) * | 2003-05-01 | 2011-06-28 | Palatin Technologies, Inc. | Melanocortin receptor-specific piperazine compounds with diamine groups |
US7727991B2 (en) | 2003-05-01 | 2010-06-01 | Palatin Technologies, Inc. | Substituted melanocortin receptor-specific single acyl piperazine compounds |
US7727990B2 (en) | 2003-05-01 | 2010-06-01 | Palatin Technologies, Inc. | Melanocortin receptor-specific piperazine and keto-piperazine compounds |
CN1925855B (zh) | 2003-12-19 | 2010-06-16 | 普莱希科公司 | 开发Ret调节剂的化合物和方法 |
US7550602B1 (en) * | 2004-01-14 | 2009-06-23 | Palatin Technologies, Inc. | Small molecule compositions for sexual dysfunction |
US7709484B1 (en) | 2004-04-19 | 2010-05-04 | Palatin Technologies, Inc. | Substituted melanocortin receptor-specific piperazine compounds |
US7498342B2 (en) | 2004-06-17 | 2009-03-03 | Plexxikon, Inc. | Compounds modulating c-kit activity |
EP1781285A2 (en) * | 2004-08-18 | 2007-05-09 | Merck & Co., Inc. | Mitotic kinesin inhibitors |
MX2007014377A (es) | 2005-05-17 | 2008-02-06 | Plexxikon Inc | Inhibidores de proteina cinasa de derivados de pirrol (2,3-b) piridina. |
TWI473808B (zh) | 2005-06-22 | 2015-02-21 | Plexxikon Inc | 用於激酶調節的化合物及方法及其適應症 |
US7834017B2 (en) | 2006-08-11 | 2010-11-16 | Palatin Technologies, Inc. | Diamine-containing, tetra-substituted piperazine compounds having identical 1- and 4-substituents |
WO2008063888A2 (en) | 2006-11-22 | 2008-05-29 | Plexxikon, Inc. | Compounds modulating c-fms and/or c-kit activity and uses therefor |
CA2695004C (en) | 2007-07-17 | 2016-01-19 | Plexxikon, Inc. | Compounds and methods for kinase modulation, and indications therefor |
RU2341527C1 (ru) * | 2007-07-17 | 2008-12-20 | Общество С Ограниченной Ответственностью "Исследовательский Институт Химического Разнообразия" | Аннелированные азагетероциклы, включающие пиримидиновый фрагмент, способ их получения и ингибиторы pi3k киназ |
RU2345996C1 (ru) * | 2007-07-17 | 2009-02-10 | Андрей Александрович Иващенко | Аннелированные азагетероциклические амиды, включающие пиримидиновый фрагмент, способ их получения и применения |
JP2011510030A (ja) * | 2008-01-22 | 2011-03-31 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 置換アミノ−ベンゾイミダゾール類、該化合物を含む医薬、これらの使用及びこれらの製造方法 |
PT2411395E (pt) * | 2009-03-23 | 2013-06-06 | Glenmark Pharmaceuticals Sa | Derivados de furopirimidinadiona como moduladores de trpa1 |
EP2955180B1 (en) | 2009-04-03 | 2018-01-10 | F. Hoffmann-La Roche AG | Propane-i-sulfonic acid {3- [5- (4- chloro-phenyl) -1h-pyrrolo [2, 3-b} pyridine-3-carbonyl] -2, 4-difluoro-phenyl} -amide compositions and uses thereof |
ES2633317T3 (es) | 2009-11-06 | 2017-09-20 | Plexxikon, Inc. | Compuestos y métodos para la modulación de quinasas, e indicaciones para ello |
WO2012109075A1 (en) | 2011-02-07 | 2012-08-16 | Plexxikon Inc. | Compounds and methods for kinase modulation, and indications therefor |
AR085279A1 (es) | 2011-02-21 | 2013-09-18 | Plexxikon Inc | Formas solidas de {3-[5-(4-cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del acido propano-1-sulfonico |
JP5990980B2 (ja) * | 2012-04-02 | 2016-09-14 | 大日本印刷株式会社 | オランザピンの中間体の製造方法 |
US9150570B2 (en) | 2012-05-31 | 2015-10-06 | Plexxikon Inc. | Synthesis of heterocyclic compounds |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9702001D0 (sv) * | 1997-05-28 | 1997-05-28 | Astra Pharma Prod | Novel compounds |
US6469014B1 (en) * | 1997-05-28 | 2002-10-22 | Astrazeneca Ab | Thieno[2,3-d] pyrimidinediones, their preparation and use in therapy |
MXPA00005506A (es) | 1997-12-05 | 2008-09-11 | Astrazeneca Uk Ltd | Compuestos novedosos. |
US6232320B1 (en) | 1998-06-04 | 2001-05-15 | Abbott Laboratories | Cell adhesion-inhibiting antiinflammatory compounds |
DK1107973T3 (da) * | 1998-08-28 | 2004-02-23 | Astrazeneca Ab | Hidtil ukendte thieno(2,3-D)pyrimidindioner, fremgangsmåde til deres fremstilling og anvendelse deraf i terapi |
GB0117583D0 (en) | 2001-07-19 | 2001-09-12 | Astrazeneca Ab | Novel compounds |
GB0118479D0 (en) * | 2001-07-28 | 2001-09-19 | Astrazeneca Ab | Novel compounds |
SE0300120D0 (sv) | 2003-01-17 | 2003-01-17 | Astrazeneca Ab | Novel compounds |
BRPI0406782A (pt) * | 2003-01-17 | 2006-01-17 | Astrazeneca Ab | Derivados de tieno-piridazinonas e seu uso na modulação de doenças autoimunes |
SE0300119D0 (sv) | 2003-01-17 | 2003-01-17 | Astrazeneca Ab | Novel compounds |
-
2001
- 2001-07-28 GB GBGB0118479.5A patent/GB0118479D0/en not_active Ceased
-
2002
- 2002-07-24 WO PCT/GB2002/003399 patent/WO2003011868A1/en active IP Right Grant
- 2002-07-24 AU AU2002319469A patent/AU2002319469B2/en not_active Ceased
- 2002-07-24 US US10/483,162 patent/US7384950B2/en not_active Expired - Fee Related
- 2002-07-24 JP JP2003517059A patent/JP4456364B2/ja not_active Expired - Fee Related
- 2002-07-24 MX MXPA04000677A patent/MXPA04000677A/es active IP Right Grant
- 2002-07-24 CN CNB028152506A patent/CN1324033C/zh not_active Expired - Fee Related
- 2002-07-24 IL IL15978502A patent/IL159785A0/xx unknown
- 2002-07-24 HU HU0402336A patent/HUP0402336A3/hu unknown
- 2002-07-24 BR BR0211262-0A patent/BR0211262A/pt not_active IP Right Cessation
- 2002-07-24 NZ NZ530495A patent/NZ530495A/en not_active IP Right Cessation
- 2002-07-24 CA CA002453274A patent/CA2453274A1/en not_active Abandoned
- 2002-07-24 ES ES02749055T patent/ES2292784T3/es not_active Expired - Lifetime
- 2002-07-24 RU RU2004102392/04A patent/RU2294937C9/ru not_active IP Right Cessation
- 2002-07-24 AT AT02749055T patent/ATE374204T1/de not_active IP Right Cessation
- 2002-07-24 DE DE60222671T patent/DE60222671T2/de not_active Expired - Lifetime
- 2002-07-24 KR KR1020047001192A patent/KR100897469B1/ko not_active IP Right Cessation
- 2002-07-24 PL PL369232A patent/PL211351B1/pl not_active IP Right Cessation
- 2002-07-24 EP EP02749055A patent/EP1414825B9/en not_active Expired - Lifetime
- 2002-07-26 AR ARP020102842A patent/AR038000A1/es active IP Right Grant
- 2002-07-26 MY MYPI20022835A patent/MY138145A/en unknown
-
2004
- 2004-01-08 IL IL159785A patent/IL159785A/en not_active IP Right Cessation
- 2004-01-19 IS IS7118A patent/IS2598B/is unknown
- 2004-01-26 ZA ZA200400574A patent/ZA200400574B/en unknown
- 2004-01-27 NO NO20040364A patent/NO328713B1/no not_active IP Right Cessation
- 2004-10-28 HK HK04108484A patent/HK1065785A1/xx not_active IP Right Cessation
-
2008
- 2008-04-29 US US12/111,792 patent/US20080207642A1/en not_active Abandoned
Also Published As
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