Nothing Special   »   [go: up one dir, main page]

AR004752A1 - 2 '- [[4'-HALO- [1,1'-BIPHENYL] -4-IL] METHYL] -5'-METHYL-SPYRO [CYCLOPENTANE-1,7' (8'H) - [3H IMIDAZO [2 , 1-B] PURIN] -4 '(5'H) -ONAS, USE OF THE SAME FOR THE PREPARATION OF A MEDICINAL PRODUCT, PHARMACEUTICAL COMPOSITION AND A PROCESS FOR ITS PREPARATION. - Google Patents

2 '- [[4'-HALO- [1,1'-BIPHENYL] -4-IL] METHYL] -5'-METHYL-SPYRO [CYCLOPENTANE-1,7' (8'H) - [3H IMIDAZO [2 , 1-B] PURIN] -4 '(5'H) -ONAS, USE OF THE SAME FOR THE PREPARATION OF A MEDICINAL PRODUCT, PHARMACEUTICAL COMPOSITION AND A PROCESS FOR ITS PREPARATION.

Info

Publication number
AR004752A1
AR004752A1 ARP960105319A ARP960105319A AR004752A1 AR 004752 A1 AR004752 A1 AR 004752A1 AR P960105319 A ARP960105319 A AR P960105319A AR P960105319 A ARP960105319 A AR P960105319A AR 004752 A1 AR004752 A1 AR 004752A1
Authority
AR
Argentina
Prior art keywords
methyl
preparation
purin
imidazo
cyclopentane
Prior art date
Application number
ARP960105319A
Other languages
Spanish (es)
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of AR004752A1 publication Critical patent/AR004752A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/20—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/42—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of mineralocorticosteroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Compuestos de 2-[[4-halo-[1,1-bifenil]4-il]metil-5-metilespiro[ ciclopentano-1,7(8h)-[3h imidazo[2,1-b)purin]-4(5h)-onas, útiles comoantihipertensivos y broncodilatores de lafórmula (I) o su sal farmacéuticamente aceptable donde X es fluoro,cloro o bromo. Dichos compuestos seusan para lapreparación de un medicamento, además se describe una composición farmacéutica y el lproceso para su preparación.2 - [[4-halo- [1,1-biphenyl] 4-yl] methyl-5-methyl-spiro [cyclopentane-1,7 (8h) - [3h imidazo [2,1-b) purin] -4 compounds (5h) -ones, useful as antihypertensives and bronchodilators of formula (I) or their pharmaceutically acceptable salt where X is fluoro, chloro or bromo. Said compounds are used for the preparation of a medicine, in addition a pharmaceutical composition and the process for its preparation are described.

ARP960105319A 1995-11-28 1996-11-25 2 '- [[4'-HALO- [1,1'-BIPHENYL] -4-IL] METHYL] -5'-METHYL-SPYRO [CYCLOPENTANE-1,7' (8'H) - [3H IMIDAZO [2 , 1-B] PURIN] -4 '(5'H) -ONAS, USE OF THE SAME FOR THE PREPARATION OF A MEDICINAL PRODUCT, PHARMACEUTICAL COMPOSITION AND A PROCESS FOR ITS PREPARATION. AR004752A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US56371795A 1995-11-28 1995-11-28

Publications (1)

Publication Number Publication Date
AR004752A1 true AR004752A1 (en) 1999-03-10

Family

ID=24251614

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960105319A AR004752A1 (en) 1995-11-28 1996-11-25 2 '- [[4'-HALO- [1,1'-BIPHENYL] -4-IL] METHYL] -5'-METHYL-SPYRO [CYCLOPENTANE-1,7' (8'H) - [3H IMIDAZO [2 , 1-B] PURIN] -4 '(5'H) -ONAS, USE OF THE SAME FOR THE PREPARATION OF A MEDICINAL PRODUCT, PHARMACEUTICAL COMPOSITION AND A PROCESS FOR ITS PREPARATION.

Country Status (8)

Country Link
EP (1) EP0863902A1 (en)
JP (1) JP2000501095A (en)
AR (1) AR004752A1 (en)
AU (1) AU1055597A (en)
CA (1) CA2237956A1 (en)
CO (1) CO4480029A1 (en)
WO (1) WO1997019947A1 (en)
ZA (1) ZA969888B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6326379B1 (en) 1998-09-16 2001-12-04 Bristol-Myers Squibb Co. Fused pyridine inhibitors of cGMP phosphodiesterase
ES2231311T3 (en) 1999-12-24 2005-05-16 Bayer Healthcare Ag TRIAZOLOTRIAZINONAS AND ITS USE.
US6777416B2 (en) 1999-12-24 2004-08-17 Bayer Aktiengesellschaft Isoxazolo pyrimidinones and the use thereof
AU781028B2 (en) 1999-12-24 2005-04-28 Bayer Aktiengesellschaft Imidazo (1,3,5) triazinones and the use thereof
EP3562828A1 (en) 2016-12-28 2019-11-06 Dart NeuroScience LLC Substituted pyrazolopyrimidinone compounds as pde2 inhibitors
MX2020005447A (en) 2017-11-27 2020-12-03 Dart Neuroscience Llc Substituted furanopyrimidine compounds as pde1 inhibitors.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL98559A0 (en) * 1990-06-21 1992-07-15 Schering Corp Polycyclic guanine derivatives
HUT72640A (en) * 1993-02-26 1996-05-28 Schering Corp 2-benzyl-polycyclic guanine derivatives, pharmaceutical compositions containing them and process for preparing them

Also Published As

Publication number Publication date
ZA969888B (en) 1997-05-26
CA2237956A1 (en) 1997-06-05
JP2000501095A (en) 2000-02-02
MX9804198A (en) 1998-10-31
CO4480029A1 (en) 1997-07-09
EP0863902A1 (en) 1998-09-16
AU1055597A (en) 1997-06-19
WO1997019947A1 (en) 1997-06-05

Similar Documents

Publication Publication Date Title
AU3959693A (en) Alpha-aminoboronic acid peptides and their use as elastase inhibitors
GB9216272D0 (en) Substituted heterocycles
IL109526A0 (en) Benzofuranyl- and thiophenyl-alkanecarboxylic acid derivatives, their preparation and pharmaceutical compositions containing them
DE69319238D1 (en) LACTAMPEPTIDES WITH HFL INHIBITING ACTIVITY
FI944802A (en) The activity of HLE proteins is inhibited by lactamide peptides
FI944823A (en) Galantamine derivatives, processes for their preparation and their use in pharmaceuticals
AR004752A1 (en) 2 '- [[4'-HALO- [1,1'-BIPHENYL] -4-IL] METHYL] -5'-METHYL-SPYRO [CYCLOPENTANE-1,7' (8'H) - [3H IMIDAZO [2 , 1-B] PURIN] -4 '(5'H) -ONAS, USE OF THE SAME FOR THE PREPARATION OF A MEDICINAL PRODUCT, PHARMACEUTICAL COMPOSITION AND A PROCESS FOR ITS PREPARATION.
HUT38097A (en) Process for preparing substituted benzopyrans and pharmaceutical compositions containing them as active substances
FI945696A (en) Lactamide peptides with HLE inhibitory activity
FI946202A0 (en) Fluorine dipeptides as inhibitors of human leukocyte elastase inhibitors
DE3070847D1 (en) Benzazepine derivatives, process and intermediates for their preparation, their use and pharmaceutical compositions containing them
HUP9800512A2 (en) Salts of bismuthum and antibiotica of the moenomycin group, process for producing them, their use and pharmaceutical compositions containing them
DE3688087D1 (en) CEPHEMIC COMPOUNDS, METHOD FOR THEIR PRODUCTION AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME.
ES2145740T3 (en) GROWTH, PREPARATION AND USE FACTOR COMPOSITIONS.
TH23729A (en) Pirolyl Tetrahydro-BenzoquinocSalene Dione Preparation and use of those substances
TH24203A (en) Optical derivatives of benzocaine pines. Preparation and application of these substances.