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AP9901515A0 - Reagent system and kit or detecting HIV infected cells. - Google Patents

Reagent system and kit or detecting HIV infected cells.

Info

Publication number
AP9901515A0
AP9901515A0 APAP/P/1999/001515A AP9901515A AP9901515A0 AP 9901515 A0 AP9901515 A0 AP 9901515A0 AP 9901515 A AP9901515 A AP 9901515A AP 9901515 A0 AP9901515 A0 AP 9901515A0
Authority
AP
ARIPO
Prior art keywords
cells
present
infected cells
relates
kit
Prior art date
Application number
APAP/P/1999/001515A
Inventor
Robert A Hallowitz
Chester F King
Original Assignee
Bio Tech Imaging Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/732,784 external-priority patent/US5714390A/en
Priority claimed from US08/732,782 external-priority patent/US5817458A/en
Application filed by Bio Tech Imaging Inc filed Critical Bio Tech Imaging Inc
Publication of AP9901515A0 publication Critical patent/AP9901515A0/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G01N33/56988—HIV or HTLV
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • AIDS & HIV (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

This invention related to blood collection and diagnostics. More particularly, the invention relates to blood collection and diagnostics utilizing techniques such as magnetic separation and photodetection. The present invention also relates to methods and an apparatus for detecting the presence of antigens displayed on the surface of cells. More preferably, the present invention relates to the detection of cells infected by human immunodeficiency virus (hiv)and related viruses. In accordance with the present invention, hiv-infected cells can be detected and separated from uninfected cells. In a preferred embodiment, separation is achieved by a magnetic field. By coating the infected cells with magnetic particles, transfer of the cells to a precise location is facilitated. A novel aspect os the present invention is a cartridge antigen test which allows for the collection and mixing of blood with reagents in one package, which can be viewed on a fluoresent microscope.
APAP/P/1999/001515A 1996-10-15 1997-10-15 Reagent system and kit or detecting HIV infected cells. AP9901515A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/732,784 US5714390A (en) 1996-10-15 1996-10-15 Cartridge test system for the collection and testing of blood in a single step
US08/732,782 US5817458A (en) 1996-10-15 1996-10-15 Reagent system for detecting HIV-infected peripheral blood lymphocytes in whole blood
PCT/US1997/018649 WO1998016101A1 (en) 1996-10-15 1997-10-15 Reagent system and kit for detecting hiv infected cells

Publications (1)

Publication Number Publication Date
AP9901515A0 true AP9901515A0 (en) 1999-06-30

Family

ID=27112456

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1999/001515A AP9901515A0 (en) 1996-10-15 1997-10-15 Reagent system and kit or detecting HIV infected cells.

Country Status (5)

Country Link
EP (1) EP0933989A1 (en)
JP (1) JP2001503859A (en)
AP (1) AP9901515A0 (en)
AU (1) AU743937B2 (en)
WO (1) WO1998016101A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010039007A1 (en) * 1996-10-15 2001-11-08 Robert Hallowitz Methods and compositions for determining latent viral load
WO2002003064A1 (en) * 2000-06-30 2002-01-10 Bio-Tech Imaging, Inc. Methods for characterizing the viral infectivity status of a host
FR2832507B1 (en) 2001-11-20 2004-02-20 Stago Diagnostica METHOD OF DETECTING ANALYTE (S) USING COLLOIDAL MAGNETIC PARTICLES
ATE521640T1 (en) * 2002-10-01 2011-09-15 Functional Genetics Inc ANTI-TSG101 ANTIBODIES AND THEIR USES IN THE TREATMENT OF VIRUS INFECTIONS
EP1771736A4 (en) * 2004-07-20 2008-08-13 Cgk Co Ltd System for detecting molecular interactions
CN107290534A (en) * 2017-07-12 2017-10-24 华讯方舟科技有限公司 A kind of blood cell capture chip and method

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4659678A (en) * 1982-09-29 1987-04-21 Serono Diagnostics Limited Immunoassay of antigens
FI844027A (en) * 1984-10-12 1986-04-13 Labsystems Oy IMMUNOLOGISKT BESTAEMNINGSFOERFARANDE.
DE68919715T2 (en) * 1988-12-28 1995-04-06 Stefan Miltenyi METHOD AND MATERIALS FOR HIGHLY GRADUATED MAGNETIC SPLITTING OF BIOLOGICAL MATERIALS.
US5054499A (en) * 1989-03-27 1991-10-08 Swierczek Remi D Disposable skin perforator and blood testing device
US5541072A (en) * 1994-04-18 1996-07-30 Immunivest Corporation Method for magnetic separation featuring magnetic particles in a multi-phase system
US5231993A (en) * 1991-11-20 1993-08-03 Habley Medical Technology Corporation Blood sampler and component tester with guide member

Also Published As

Publication number Publication date
JP2001503859A (en) 2001-03-21
EP0933989A1 (en) 1999-08-11
WO1998016101A1 (en) 1998-04-23
AU743937B2 (en) 2002-02-07
AU4822497A (en) 1998-05-11

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