NO995036D0 - 5,7-Disubstituted 4-Aminopyrido [2,3-d] Pyrimidine Compounds and Their Use as Adenosine Kinase Inhibitors - Google Patents

5,7-Disubstituted 4-Aminopyrido [2,3-d] Pyrimidine Compounds and Their Use as Adenosine Kinase Inhibitors

Info

Publication number: NO995036D0
Authority: NO; Norway
Prior art keywords: aminopyrido; disubstituted; kinase inhibitors; pyrimidine compounds; adenosine kinase
Prior art date: 1997-04-16

Application number

NO995036A

Other languages

Norwegian (no)

Other versions

NO995036L (en

Inventor

Shripad S Bhagwat

Chih-Hung Lee

Marlon D Cowart

Jeffrey Mckie

Anne Laure Grillot

Original Assignee

Abbott Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-16

Filing date

1999-10-15

Publication date

1999-10-15

1999-10-15 Application filed by Abbott Lab filed Critical Abbott Lab

1999-10-15 Publication of NO995036D0 publication Critical patent/NO995036D0/en

1999-10-15 Publication of NO995036L publication Critical patent/NO995036L/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Heart & Thoracic Surgery (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Neurology (AREA)
Cardiology (AREA)
Epidemiology (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Immunology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO995036A 1997-04-16 1999-10-15 5,7-Disubstituted 4-Aminopyrido [2,3-d] Pyrimidine Compounds and Their Use as Adenosine Kinase Inhibitors NO995036L (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US83821697A	1997-04-16	1997-04-16
PCT/US1998/007207 WO1998046605A1 (en)	1997-04-16	1998-04-14	5,7-disubstituted 4-aminopyrido[2,3-d]pyrimidine compounds and their use as adenosine kinase inhibitors

Publications (2)

Publication Number	Publication Date
NO995036D0 true NO995036D0 (en)	1999-10-15
NO995036L NO995036L (en)	1999-10-15

Family

ID=25276561

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO995036A NO995036L (en)	1997-04-16	1999-10-15	5,7-Disubstituted 4-Aminopyrido [2,3-d] Pyrimidine Compounds and Their Use as Adenosine Kinase Inhibitors

Country Status (18)

Country	Link
EP (1)	EP0989986A1 (en)
JP (1)	JP2001520655A (en)
KR (1)	KR20010006509A (en)
CN (1)	CN1252070A (en)
AR (1)	AR012436A1 (en)
AU (1)	AU7108398A (en)
BG (1)	BG103842A (en)
BR (1)	BR9809055A (en)
CA (1)	CA2286909A1 (en)
CO (1)	CO4940446A1 (en)
HU (1)	HUP0001434A3 (en)
IL (1)	IL131618A0 (en)
NO (1)	NO995036L (en)
PL (1)	PL336304A1 (en)
SK (1)	SK141799A3 (en)
TR (1)	TR199902455T2 (en)
WO (1)	WO1998046605A1 (en)
ZA (1)	ZA983177B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000023444A1 (en) *	1998-10-21	2000-04-27	Abbott Laboratories	5,7-disubstituted-4-aminopyrido[2,3-d]pyrimidine compounds
CN100376571C (en)	2001-02-12	2008-03-26	霍夫曼-拉罗奇有限公司	6-substituted pyrido-pyrimidines
CN1627944A (en)	2002-01-17	2005-06-15	神经能质公司	Substituted quinazolin-4-ylamine analogues as modulators of capsaicin
DE10335183A1 (en) *	2003-07-30	2005-02-24	Bayer Cropscience Ag	Fungicidal drug combinations
DE602006010564D1 (en) *	2005-07-21	2009-12-31	Hoffmann La Roche	PYRIDOÄ2,3-DÜPYRIMIDIN-2,4-DIAMINE COMPOUNDS AS PTPIB INHIBITORS
WO2007081517A2 (en)	2005-12-21	2007-07-19	Abbott Laboratories	Anti-viral compounds
ATE541844T1 (en) *	2005-12-21	2012-02-15	Abbott Lab	ANTIVIRAL COMPOUNDS
CA2672737A1 (en)	2006-12-20	2008-11-06	Abbott Laboratories	Anti-viral compounds
KR101567454B1 (en)	2007-08-27	2015-11-09	헬리콘 테라퓨틱스 인코퍼레이티드	Therapeutic isoxazole compounds
KR20100055456A (en)	2007-08-31	2010-05-26	에자이 알앤드디 매니지먼트 가부시키가이샤	Polycyclic compound
DE102007061764A1 (en) *	2007-12-20	2009-06-25	Bayer Healthcare Ag	Anellated cyanopyridines and their use
NZ594776A (en) *	2009-02-26	2013-05-31	Eisai R&D Man Co Ltd	Nitrogen-containing fused heterocyclic compounds and their use as beta amyloid production inhibitors
US9550750B2 (en)	2012-10-05	2017-01-24	Merck Sharp & Dohme Corp.	Indoline compounds as aldosterone synthase inhibitors
KR102375929B1 (en)	2016-03-31	2022-03-16	온크터널 테라퓨틱스, 인코포레이티드.	Indoline analogs and uses thereof
CN110256420B (en) *	2019-05-07	2020-04-28	江西中医药大学	Tetrahydropyridopyrimidine derivatives and preparation methods and uses thereof
CN110283171A (en) *	2019-07-17	2019-09-27	鼎泰(南京)临床医学研究有限公司	Compound of the one kind containing Pyridopyrimidine -4- amine structure, pharmaceutical composition and its application

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5324731A (en) *	1989-02-14	1994-06-28	Amira, Inc.	Method of inhibiting transformation of cells in which purine metabolic enzyme activity is elevated
IL112249A (en) *	1994-01-25	2001-11-25	Warner Lambert Co	Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds
US6143749A (en) *	1995-06-07	2000-11-07	Abbott Laboratories	Heterocyclic substituted cyclopentane compounds

1998
- 1998-04-14 SK SK1417-99A patent/SK141799A3/en unknown
- 1998-04-14 EP EP98918093A patent/EP0989986A1/en not_active Withdrawn
- 1998-04-14 JP JP54408898A patent/JP2001520655A/en active Pending
- 1998-04-14 TR TR1999/02455T patent/TR199902455T2/en unknown
- 1998-04-14 CA CA002286909A patent/CA2286909A1/en not_active Abandoned
- 1998-04-14 AU AU71083/98A patent/AU7108398A/en not_active Abandoned
- 1998-04-14 IL IL13161898A patent/IL131618A0/en unknown
- 1998-04-14 PL PL98336304A patent/PL336304A1/en unknown
- 1998-04-14 WO PCT/US1998/007207 patent/WO1998046605A1/en not_active Application Discontinuation
- 1998-04-14 KR KR1019997009599A patent/KR20010006509A/en not_active Application Discontinuation
- 1998-04-14 BR BR9809055-0A patent/BR9809055A/en not_active Application Discontinuation
- 1998-04-14 CN CN98804151A patent/CN1252070A/en active Pending
- 1998-04-14 HU HU0001434A patent/HUP0001434A3/en unknown
- 1998-04-15 ZA ZA983177A patent/ZA983177B/en unknown
- 1998-04-15 AR ARP980101733A patent/AR012436A1/en unknown
- 1998-04-16 CO CO98020979A patent/CO4940446A1/en unknown
1999
- 1999-10-15 NO NO995036A patent/NO995036L/en not_active Application Discontinuation
- 1999-10-29 BG BG103842A patent/BG103842A/en active Pending

Also Published As

Publication number	Publication date
PL336304A1 (en)	2000-06-19
AU7108398A (en)	1998-11-11
BG103842A (en)	2000-06-30
SK141799A3 (en)	2000-08-14
HUP0001434A2 (en)	2000-10-28
CN1252070A (en)	2000-05-03
CO4940446A1 (en)	2000-07-24
ZA983177B (en)	1999-01-22
WO1998046605A1 (en)	1998-10-22
BR9809055A (en)	2000-08-08
EP0989986A1 (en)	2000-04-05
HUP0001434A3 (en)	2001-01-29
JP2001520655A (en)	2001-10-30
AR012436A1 (en)	2000-10-18
NO995036L (en)	1999-10-15
IL131618A0 (en)	2001-01-28
TR199902455T2 (en)	2000-01-21
KR20010006509A (en)	2001-01-26
CA2286909A1 (en)	1998-10-22

Publication	Publication Date	Title
DK1235830T3 (en)	2004-03-29	Pyrrolo [2,3-d] pyrimidine compounds as protein kinase inhibitors
NO20023527D0 (en)	2002-07-24	Pyrido (2,3-d) pyrimidine-2,7-diamine kinase inhibitors
HRP20020798A2 (en)	2004-02-29	5-ALKYLPYRIDO[2,3-d]PYRIMIDINES TYROZINE KINASE INHIBITORS
ATE284404T1 (en)	2004-12-15	PYRAZOLO(4,3-D)PYRIMIDINE DERIVATIVES
FI944305A0 (en)	1994-09-16	Pyrido (2,3-d) pyrimidine derivatives as phosphodiesterase inhibitors
PT1087970E (en)	2004-06-30	PYRIMIDINE COMPOUNDS 2,3-D \| PYRIMIDINE
NO20002121D0 (en)	2000-04-26	Benzothiazol-protein-tyrosine kinase inhibitors
NO20006454L (en)	2001-02-15	Pyrrolo (2,3-d) pyrimidine
NO995695D0 (en)	1999-11-19	Substituted pyrazoles as p38 kinase inhibitors
NO995036D0 (en)	1999-10-15	5,7-Disubstituted 4-Aminopyrido [2,3-d] Pyrimidine Compounds and Their Use as Adenosine Kinase Inhibitors
TR199801367A3 (en)	1999-02-22	5H-thiazole (3,2-a) pyrimidine derivatives
NO20010684D0 (en)	2001-02-09	Substituted 1,8-Naphthyridin-4 (1H) -one as phosphodiesterase 4 inhibitors
NO996043D0 (en)	1999-12-08	3-Substituted 3,4-dihydro-thieno [2,3-d] pyrimidine derivatives, their preparation and use
NO20020931D0 (en)	2002-02-26	Pyrrolo [2,3-d] pyrimidine nucleoside analogs
DE50001191D1 (en)	2003-03-06	PYRAZOLO [4, 3-D] PYRIMIDINE
NO995033D0 (en)	1999-10-15	6,7-disubstituted-4-aminopyrido [2,3-D] pyrimidine
DE50103649D1 (en)	2004-10-21	2-aminoalkyl-THIENO [2,3-D] PYRIMIDINES

Legal Events

Date	Code	Title	Description
2001-12-17	FC2A	Withdrawal, rejection or dismissal of laid open patent application