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NO994108L - Fremgangsmaate ved fremstilling av 4H-4-okso-kinolizin-3-karboksylsyrederivater - Google Patents

Fremgangsmaate ved fremstilling av 4H-4-okso-kinolizin-3-karboksylsyrederivater

Info

Publication number
NO994108L
NO994108L NO994108A NO994108A NO994108L NO 994108 L NO994108 L NO 994108L NO 994108 A NO994108 A NO 994108A NO 994108 A NO994108 A NO 994108A NO 994108 L NO994108 L NO 994108L
Authority
NO
Norway
Prior art keywords
preparation
quinolizine
oxo
carboxylic acid
acid derivatives
Prior art date
Application number
NO994108A
Other languages
English (en)
Other versions
NO994108D0 (no
Inventor
Wei-Bo Wang
Francis A J Kerdesky
Chi-Nung W Hsiao
Qun Li
Daniel T Chu
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of NO994108D0 publication Critical patent/NO994108D0/no
Publication of NO994108L publication Critical patent/NO994108L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Fremgangsmåte ved fremstillingen av en forbindelse som har formel (a) hvor R1, R2, R3, R4 og R5 er definert, fra et enamin ved kjedeekspansjon og ringlukking etterfulgt av ytterligere derivatisering, behandling med en 3-alkoksyl- acryloylforbindelse, en ny ringlukking, og konvertering av en hydroksylgruppe til en utgående gruppe.
NO994108A 1997-02-26 1999-08-25 Fremgangsmaate ved fremstilling av 4H-4-okso-kinolizin-3-karboksylsyrederivater NO994108L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/806,806 US5693813A (en) 1997-02-26 1997-02-26 Process for preparation of 4H-4-oxo-quinolizine-3-carboxylic acid
PCT/US1998/002327 WO1998038191A1 (en) 1997-02-26 1998-02-06 Process for preparation of 4h-4-oxo-quinolizine-3-carboxylic acid derivatives

Publications (2)

Publication Number Publication Date
NO994108D0 NO994108D0 (no) 1999-08-25
NO994108L true NO994108L (no) 1999-10-25

Family

ID=25194886

Family Applications (1)

Application Number Title Priority Date Filing Date
NO994108A NO994108L (no) 1997-02-26 1999-08-25 Fremgangsmaate ved fremstilling av 4H-4-okso-kinolizin-3-karboksylsyrederivater

Country Status (27)

Country Link
US (1) US5693813A (no)
EP (1) EP0971919B1 (no)
JP (1) JP2001513104A (no)
KR (1) KR20000075700A (no)
CN (1) CN1248256A (no)
AR (1) AR011167A1 (no)
AT (1) ATE207920T1 (no)
AU (1) AU724353B2 (no)
BG (1) BG103737A (no)
BR (1) BR9807726A (no)
CA (1) CA2281734A1 (no)
CO (1) CO4920239A1 (no)
CZ (1) CZ290252B6 (no)
DE (1) DE69802274T2 (no)
DK (1) DK0971919T3 (no)
ES (1) ES2168740T3 (no)
HU (1) HUP0001323A3 (no)
IL (1) IL131050A0 (no)
NO (1) NO994108L (no)
NZ (1) NZ336876A (no)
PL (1) PL335373A1 (no)
PT (1) PT971919E (no)
SK (1) SK115299A3 (no)
TR (1) TR199901956T2 (no)
TW (1) TW444017B (no)
WO (1) WO1998038191A1 (no)
ZA (1) ZA98836B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011031745A1 (en) 2009-09-09 2011-03-17 Achaogen, Inc. Antibacterial fluoroquinolone analogs
CN106432222A (zh) * 2016-09-19 2017-02-22 丹诺医药(苏州）有限公司 8‑氯‑1‑环丙基‑7‑氟‑9‑甲基‑4‑氧‑4‑氢‑喹嗪‑3‑羧酸酯及其制备方法
CN106543170B (zh) * 2016-10-27 2018-02-23 丹诺医药(苏州）有限公司 8‑氯‑1‑环丙基‑7‑氟‑9‑甲基‑4‑氧‑4‑氢‑喹嗪‑3‑羧酸酯及其合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0527889T3 (da) * 1990-05-02 2000-12-18 Abbott Lab Forbindelser af quinolizinon-type
US5599816A (en) * 1990-05-02 1997-02-04 Abbott Laboratories Quinolizinone type compounds
EP0723545B1 (en) * 1993-10-14 2002-05-08 Abbott Laboratories Quinolizinone type compounds
IL122296A0 (en) * 1995-06-06 1998-04-05 Abbott Lab Quinolizinone type compounds

Also Published As

Publication number Publication date
AR011167A1 (es) 2000-08-02
CZ288199A3 (cs) 1999-11-17
KR20000075700A (ko) 2000-12-26
BG103737A (en) 2000-06-30
ATE207920T1 (de) 2001-11-15
TW444017B (en) 2001-07-01
EP0971919A1 (en) 2000-01-19
CN1248256A (zh) 2000-03-22
TR199901956T2 (xx) 1999-10-21
SK115299A3 (en) 2000-01-18
AU6271898A (en) 1998-09-18
JP2001513104A (ja) 2001-08-28
NO994108D0 (no) 1999-08-25
HUP0001323A2 (hu) 2000-10-28
EP0971919B1 (en) 2001-10-31
DE69802274D1 (de) 2001-12-06
BR9807726A (pt) 2000-02-15
DK0971919T3 (da) 2002-01-28
DE69802274T2 (de) 2002-07-18
AU724353B2 (en) 2000-09-21
ES2168740T3 (es) 2002-06-16
CO4920239A1 (es) 2000-05-29
CA2281734A1 (en) 1998-09-03
US5693813A (en) 1997-12-02
CZ290252B6 (cs) 2002-06-12
IL131050A0 (en) 2001-01-28
ZA98836B (en) 1998-08-05
PT971919E (pt) 2002-04-29
NZ336876A (en) 2000-12-22
PL335373A1 (en) 2000-04-25
WO1998038191A1 (en) 1998-09-03
HUP0001323A3 (en) 2001-01-29

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Legal Events

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