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NO973107L - Programmerte celledödgener og proteiner - Google Patents

Programmerte celledödgener og proteiner

Info

Publication number
NO973107L
NO973107L NO973107A NO973107A NO973107L NO 973107 L NO973107 L NO 973107L NO 973107 A NO973107 A NO 973107A NO 973107 A NO973107 A NO 973107A NO 973107 L NO973107 L NO 973107L
Authority
NO
Norway
Prior art keywords
ich
ced
cells
cell death
gene
Prior art date
Application number
NO973107A
Other languages
English (en)
Norwegian (no)
Other versions
NO973107D0 (no
Inventor
Junying Yuan
Masayuki Miura
Original Assignee
Gen Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Hospital Corp filed Critical Gen Hospital Corp
Publication of NO973107D0 publication Critical patent/NO973107D0/no
Publication of NO973107L publication Critical patent/NO973107L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8139Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F02COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
    • F02BINTERNAL-COMBUSTION PISTON ENGINES; COMBUSTION ENGINES IN GENERAL
    • F02B75/00Other engines
    • F02B75/02Engines characterised by their cycles, e.g. six-stroke
    • F02B2075/022Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle
    • F02B2075/027Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle four

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO973107A 1995-01-04 1997-07-03 Programmerte celledödgener og proteiner NO973107L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/368,704 US6087160A (en) 1993-06-24 1995-01-04 Programmed cell death genes and proteins
PCT/US1996/000177 WO1996020721A1 (en) 1995-01-04 1996-01-04 Programmed cell death genes and proteins

Publications (2)

Publication Number Publication Date
NO973107D0 NO973107D0 (no) 1997-07-03
NO973107L true NO973107L (no) 1997-08-26

Family

ID=23452396

Family Applications (1)

Application Number Title Priority Date Filing Date
NO973107A NO973107L (no) 1995-01-04 1997-07-03 Programmerte celledödgener og proteiner

Country Status (10)

Country Link
US (2) US6087160A (es)
EP (1) EP0808169A4 (es)
JP (1) JPH11500304A (es)
AU (1) AU4747296A (es)
CA (1) CA2209526A1 (es)
FI (1) FI972821A (es)
IL (1) IL116671A0 (es)
MX (1) MX9705039A (es)
NO (1) NO973107L (es)
WO (1) WO1996020721A1 (es)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993025685A1 (en) * 1992-06-12 1993-12-23 Massachusetts Institute Of Technology Cloning and characterization of the cell death genes ced-3 and ced-4
US6015665A (en) * 1995-02-13 2000-01-18 The Regents Of The University Of Michigan Method and composition for regulating apoptosis
US6060238A (en) * 1995-02-13 2000-05-09 The Regents Of The University Of Michigan Method and composition for regulating apoptosis
US7097972B1 (en) 1995-02-13 2006-08-29 Regents Of The University Of Michigan Method and composition for regulating apoptosis
US7807783B1 (en) 1995-04-03 2010-10-05 The Regents Of The University Of Michigan Methods and compositions for regulating FAS-associated apoptosis
US6747138B1 (en) 1995-04-03 2004-06-08 Regents Of The University Of Michigan Methods and compositions for regulating Fas-associated apoptosis
US6214572B1 (en) * 1996-08-09 2001-04-10 The General Hospital Corporation Programmed cell death and ICH-3
US5897992A (en) 1996-09-27 1999-04-27 Cold Spring Harbor Laboratory Cell-free assay using oncogene-induced apoptosis in drug-resistant cells
US6184210B1 (en) 1997-10-10 2001-02-06 Cytovia, Inc. Dipeptide apoptosis inhibitors and the use thereof
US6342611B1 (en) 1997-10-10 2002-01-29 Cytovia, Inc. Fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for capsases and other enzymes and the use thereof
US6153591A (en) * 1998-03-16 2000-11-28 Cytovia, Inc. Dipeptide caspase inhibitors and the use thereof
AU751167B2 (en) * 1998-04-16 2002-08-08 General Hospital Corporation, The Programmed cell death and caspase-12
EP1100520B1 (en) 1998-07-21 2004-09-22 Cytovia, Inc. Novel fluorescence dyes and their applications for whole cell fluorescence screening assays for caspases, peptidases, proteases and other enzymes and the use thereof
ATE336480T1 (de) 1999-03-16 2006-09-15 Cytovia Inc Substituierte 2-aminobenzamin caspase inhibitoren und ihre verwendung
AU4213500A (en) 1999-04-09 2000-11-14 Cytovia, Inc. Caspase inhibitors and the use thereof
US6462041B1 (en) 1999-05-21 2002-10-08 Cytovia, Inc. Gambogic acid, analogs and derivatives as activators of caspases and inducers of apoptosis
EP1212295B1 (en) 1999-08-27 2008-10-01 Cytovia, Inc. Substituted alpha-hydroxy acid caspase inhibitors and the use thereof
US6566338B1 (en) 1999-10-12 2003-05-20 Cytovia, Inc. Caspase inhibitors for the treatment and prevention of chemotherapy and radiation therapy induced cell death
JP2003513967A (ja) 1999-11-05 2003-04-15 サイトビア インコーポレイテッド カスパーゼのアクチベーターおよびアポトーシスのインデューサーとしての置換4hクロメンおよびアナログ、ならびにその使用
JP2003520854A (ja) 2000-01-27 2003-07-08 サイトビア インコーポレイテッド カスパーゼのアクチベーターおよびアポトーシスのインデューサーとしての置換ニコチンアミドおよび類似物およびそれらの使用
CA2406271A1 (en) 2000-04-18 2001-10-25 Cytovia, Inc. Substituted 1,4-thiazepine and analogs and their use as activators of caspases
WO2002012496A1 (fr) * 2000-08-03 2002-02-14 Japan As Represented By The President Of The University Of Tokyo Nouvelle proteine dependante de p53 et associee a l'apoptose et procede de balayage d'un agent de regulation de l'apoptose
AU2001278135A1 (en) 2000-08-03 2002-02-18 Cytovia, Inc. Method of identifying immunosuppressive agents
AU2001289068A1 (en) * 2000-09-20 2002-04-02 Isis Pharmaceuticals, Inc. Antisense modulation of caspase 2 expression
US6716851B2 (en) 2000-12-12 2004-04-06 Cytovia, Inc. Substituted 2-aryl-4-arylaminopyrimidines and analogs as activators or caspases and inducers of apoptosis and the use thereof
ATE450531T1 (de) 2001-05-16 2009-12-15 Cytovia Inc Substituierte 4h-chromene und analoga als aktivatoren von caspasen und induktoren von apoptose, und deren verwendung als antikrebsmittel
WO2002098420A1 (en) * 2001-06-01 2002-12-12 Cytovia, Inc. 4-substituted-1-(arylmethylidene)thiosemicarbazide, 4-substituted-1-(arylcarbonyl)thiosemicarbazide and analogs as activators of caspases and inducers of apoptosis and the use thereof
RU2003138074A (ru) 2001-06-08 2005-02-20 Цитови Инк. (US) Замещенные 3-арил-5-арил-[1,2,4]-оксадиазолы и их аналоги в качестве активаторов каспаз и индукторов апоптоза, а также их применение
WO2003097806A2 (en) 2002-05-16 2003-11-27 Cytovia, Inc. Substituted 4-aryl-4h-pyrrolo[2,3-h]chromenes and analogs as activators of caspases and inducers of apoptosis and the use thereof
US7476741B2 (en) 2002-05-16 2009-01-13 Cytovia, Inc. Substituted 4H-chromens, 2H-chromenes, chromans and analogs as activators of caspases and inducers of apoptosis and the use thereof
EP1581213A4 (en) 2002-12-18 2008-11-19 Cytovia Inc 3,5-DISUBSTITUES-1,2,4-OXADIAZOLES AND ANALOGS AS ACTIVATORS OF CASPASES AND APOPTOSIS PROMOTERS, AND USE THEREOF
NZ544472A (en) 2003-07-03 2009-04-30 Myriad Genetics Inc Compounds and therapeutical use thereof
CN1954882A (zh) * 2005-10-14 2007-05-02 李海 长效人重组可溶性肿瘤坏死因子α受体在制备防治肝衰竭药物中的用途
US10345292B2 (en) 2014-09-09 2019-07-09 Boehringer Ingelheim Animal Health Inc. Mammalian cell lines expressing functional nematode acetylcholine receptors and use thereof for high-throughput screening assays

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7775991A (en) * 1990-04-04 1991-10-30 Immunex Corporation Interleukin 1beta protease
EP0533350B1 (en) * 1991-08-16 1999-05-26 Merck & Co. Inc. DNA encoding precursor interleukin 1B converting enzyme
ATE257517T1 (de) * 1991-08-30 2004-01-15 Vertex Pharma Interleukin 1-beta protease und ihre inhibitoren
GB9124986D0 (en) * 1991-11-25 1992-01-22 Greenberg Arnold H Natural killer cell granule protein
WO1993025685A1 (en) * 1992-06-12 1993-12-23 Massachusetts Institute Of Technology Cloning and characterization of the cell death genes ced-3 and ced-4
EP0672151A1 (en) * 1992-06-12 1995-09-20 Massachusetts Institute Of Technology Inhibitors of ced-3 and related proteins
WO1995000160A1 (en) * 1993-06-24 1995-01-05 The General Hospital Corporation Programmed cell death genes and proteins
WO1996000297A1 (en) * 1994-06-23 1996-01-04 Human Genome Sciences, Inc. INTERLEUKIN-1 β CONVERTING ENZYME LIKE APOPTOSIS PROTEASE-1 AND 2

Also Published As

Publication number Publication date
FI972821A (fi) 1997-09-03
AU4747296A (en) 1996-07-24
IL116671A0 (en) 1996-05-14
US20030124105A1 (en) 2003-07-03
MX9705039A (es) 1997-10-31
EP0808169A4 (en) 2002-09-11
US6087160A (en) 2000-07-11
NO973107D0 (no) 1997-07-03
WO1996020721A1 (en) 1996-07-11
EP0808169A1 (en) 1997-11-26
JPH11500304A (ja) 1999-01-12
FI972821A0 (fi) 1997-06-30
CA2209526A1 (en) 1996-07-11

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Miura et al. Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3
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