Nothing Special   »   [go: up one dir, main page]

NO962023D0 - Endotelin-konverterende enzym - Google Patents

Endotelin-konverterende enzym

Info

Publication number
NO962023D0
NO962023D0 NO962023A NO962023A NO962023D0 NO 962023 D0 NO962023 D0 NO 962023D0 NO 962023 A NO962023 A NO 962023A NO 962023 A NO962023 A NO 962023A NO 962023 D0 NO962023 D0 NO 962023D0
Authority
NO
Norway
Prior art keywords
pct
date
converting enzyme
endothelin converting
enzymes
Prior art date
Application number
NO962023A
Other languages
English (en)
Other versions
NO962023L (no
Inventor
Burkhard Kroger
Harald Seulberger
Thomas Meyer
Martin Schmidt
Elard Jacob
Rainer Otter
Thomas Subkowski
Heinz Hillen
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19934339100 external-priority patent/DE4339100A1/de
Priority claimed from DE19944403665 external-priority patent/DE4403665A1/de
Priority claimed from DE19944412372 external-priority patent/DE4412372A1/de
Application filed by Basf Ag filed Critical Basf Ag
Publication of NO962023D0 publication Critical patent/NO962023D0/no
Publication of NO962023L publication Critical patent/NO962023L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489—Metalloendopeptidases (3.4.24)
    • C12N9/6497—Endothelin-converting enzyme (3.4.24.71)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • C12Y304/24071—Endothelin-converting enzyme 1 (3.4.24.71)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
NO962023A 1993-11-16 1996-05-15 Endotelin-konverterende enzym NO962023L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19934339100 DE4339100A1 (de) 1993-11-16 1993-11-16 Endothelinkonversionsenzym-1 (ECE-1)
DE19944403665 DE4403665A1 (de) 1994-02-07 1994-02-07 Endothelinkonversionsenzym (ECE)
DE19944412372 DE4412372A1 (de) 1994-04-12 1994-04-12 Endothelinkonversionsenzym (ECE)
PCT/EP1994/003706 WO1995014095A1 (de) 1993-11-16 1994-11-10 Endothelinkonversionsenzym (ece)

Publications (2)

Publication Number Publication Date
NO962023D0 true NO962023D0 (no) 1996-05-15
NO962023L NO962023L (no) 1996-07-16

Family

ID=27205762

Family Applications (1)

Application Number Title Priority Date Filing Date
NO962023A NO962023L (no) 1993-11-16 1996-05-15 Endotelin-konverterende enzym

Country Status (18)

Country Link
US (1) US6066502A (no)
EP (1) EP0728209B1 (no)
JP (1) JPH09505733A (no)
KR (1) KR960705934A (no)
CN (1) CN1141651A (no)
AT (1) ATE315656T1 (no)
AU (1) AU8107094A (no)
BR (1) BR9408077A (no)
CA (1) CA2176507A1 (no)
CZ (1) CZ139496A3 (no)
DE (1) DE59410427D1 (no)
FI (1) FI962047A (no)
HU (1) HUT75554A (no)
NO (1) NO962023L (no)
NZ (1) NZ275817A (no)
PL (1) PL314480A1 (no)
SK (1) SK59896A3 (no)
WO (1) WO1995014095A1 (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6255468B1 (en) * 1998-05-07 2001-07-03 Smithkline Beecham Plc MPROT12 polynucleotides and methods thereof
WO2001021773A2 (en) * 1999-09-24 2001-03-29 Lexicon Genetics Incorporated Human endothelin converting enzyme-like proteins and polynucleotides encoding the same
ATE312351T1 (de) * 2004-02-13 2005-12-15 Brahms Ag Verfahren zur bestimmung der bildung von endothelinen zu zwecken der medizinischen diagnostik, sowie antikörper und kits für die durchführung eines solchen verfahrens
US9062347B2 (en) 2007-07-27 2015-06-23 The Regents Of The University Of Colorado, A Body Corporate Endothelin single nucleotide polymorphisms and methods of predicting β-adrenergic receptor targeting agent efficacy

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2966939B2 (ja) * 1990-12-07 1999-10-25 日清製粉株式会社 ヒト細胞由来のエンドセリン変換酵素
WO1992013944A1 (en) * 1991-02-04 1992-08-20 Berlex Laboratories, Inc. Endothelin converting enzyme

Also Published As

Publication number Publication date
HUT75554A (en) 1997-05-28
NO962023L (no) 1996-07-16
HU9601298D0 (en) 1996-07-29
DE59410427D1 (en) 2006-04-06
US6066502A (en) 2000-05-23
CZ139496A3 (en) 1997-10-15
AU8107094A (en) 1995-06-06
FI962047A (fi) 1996-07-12
KR960705934A (ko) 1996-11-08
EP0728209B1 (de) 2006-01-11
SK59896A3 (en) 1997-07-09
EP0728209A1 (de) 1996-08-28
FI962047A0 (fi) 1996-05-14
PL314480A1 (en) 1996-09-16
CA2176507A1 (en) 1995-05-26
ATE315656T1 (de) 2006-02-15
JPH09505733A (ja) 1997-06-10
WO1995014095A1 (de) 1995-05-26
NZ275817A (en) 1997-02-24
CN1141651A (zh) 1997-01-29
BR9408077A (pt) 1997-08-12

Similar Documents

Publication Publication Date Title
AU6414196A (en) A modified enzyme with lipolytic activity
FI965031A (fi) Sieni, jossa AreA-geeni on muunnettu, ja Aspergillus oryzaesta peräisin oleva areA-geeni
FI934332A0 (fi) Nya proteaser
EP1209237A3 (en) Synthetic DNA sequence having enhanced insecticidal activity in maize
HK1022701A1 (en) Exendin analogues, processes for their preparationand medicaments containing them exendin.
HUT73962A (en) New bacillus thuringiensis strains and their insecticidal proteins
ATE397062T1 (de) Chimäre polypeptide, die das fragment b des shigatoxins sowie peptide von therapeutischem interesse enthalten
IL135687A0 (en) A novel human checkpoint kinase, hcds1, compositions and methods
AU7617796A (en) Variants of human recombinant interferon-gamma (rhu-ifn-gamma) having increased heat-stability
DK0418945T3 (da) Forgreningsenzym og dets anvendelse
NO962023L (no) Endotelin-konverterende enzym
ES8700051A1 (es) Un procedimiento para preparar una composicion oral estable,formadora de espuma
PE20000759A1 (es) Gen de la citocroma oxidasa de hidroquinona del tipo bd
ES2171136A1 (es) Enzima con actividad proteolitica construccion de adn que comprende una secuencia de adn que codifica dicha enzima y sus aplicaciones.
AU3384495A (en) Or-1 on orphan receptor belonging to the nuclear receptor family
ATE318910T1 (de) Cholesterinoxidase aus brevibacterium sterolicum
GB9203821D0 (en) Improvements in or relating to malaria vaccine
WO2000024765A3 (en) Chlamydia antigens and corresponding dna fragments and uses thereof
GB2357507A (en) Peptide fragments of cholera toxin B or enterotoxin B as vaccine adjuvants
AU1993201A (en) Nucleic acid sequences of hyperplasia and tumours of the thyroid
MX9804053A (es) Malation carboxilesterasa.
NZ511166A (en) Genes that increase the production of HMG-CoA reductase inhibitor, ML-236B
GB9609261D0 (en) Gene expression in monocytes and microphages
WO2000032794A3 (en) Chlamydia antigens and corresponding dna fragments and uses thereof
EP0945512A3 (en) Novel serine proteases

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application