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NO950733D0 - Fremgangsmåte for isolering og rensing av proteiner som er avhengig av vitamin K - Google Patents

Fremgangsmåte for isolering og rensing av proteiner som er avhengig av vitamin K

Info

Publication number
NO950733D0
NO950733D0 NO950733A NO950733A NO950733D0 NO 950733 D0 NO950733 D0 NO 950733D0 NO 950733 A NO950733 A NO 950733A NO 950733 A NO950733 A NO 950733A NO 950733 D0 NO950733 D0 NO 950733D0
Authority
NO
Norway
Prior art keywords
vitamin
isolating
purifying protein
protein dependent
dependent
Prior art date
Application number
NO950733A
Other languages
English (en)
Other versions
NO322372B1 (no
NO950733L (no
Inventor
Bernhard Fischer
Artur Mitterer
Friedrich Dorner
Original Assignee
Immuno Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immuno Ag filed Critical Immuno Ag
Publication of NO950733D0 publication Critical patent/NO950733D0/no
Publication of NO950733L publication Critical patent/NO950733L/no
Publication of NO322372B1 publication Critical patent/NO322372B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/647—Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6429—Thrombin (3.4.21.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21005—Thrombin (3.4.21.5)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO19950733A 1994-02-28 1995-02-27 Fremgangsmate for separasjon av et vitamin K-avhengig protein fra ikke-vitamin K-avhengige, medfolgende proteiner fra en proteinholdig losning NO322372B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4406515A DE4406515C1 (de) 1994-02-28 1994-02-28 Verfahren zur Isolierung und Reinigung Vitamin K-abhängiger Proteine

Publications (3)

Publication Number Publication Date
NO950733D0 true NO950733D0 (no) 1995-02-27
NO950733L NO950733L (no) 1995-08-29
NO322372B1 NO322372B1 (no) 2006-09-25

Family

ID=6511421

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19950733A NO322372B1 (no) 1994-02-28 1995-02-27 Fremgangsmate for separasjon av et vitamin K-avhengig protein fra ikke-vitamin K-avhengige, medfolgende proteiner fra en proteinholdig losning

Country Status (13)

Country Link
US (1) US5633350A (no)
EP (1) EP0669342B1 (no)
JP (1) JPH07258286A (no)
AT (1) ATE205218T1 (no)
CA (1) CA2143510C (no)
CZ (1) CZ290471B6 (no)
DE (1) DE4406515C1 (no)
DK (1) DK0669342T3 (no)
ES (1) ES2161790T3 (no)
FI (1) FI116526B (no)
HU (1) HU219828B (no)
NO (1) NO322372B1 (no)
SK (1) SK22695A3 (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2245824T3 (es) * 1998-04-15 2006-01-16 Novo Nordisk A/S Nuevo proceso de separacion de proteinas utilizando un eluyente que contiene ca++.
WO2002008249A1 (fr) * 2000-07-21 2002-01-31 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Procede de purification de la proteine de liaison a l'ion calcium
US7897734B2 (en) 2003-03-26 2011-03-01 Novo Nordisk Healthcare Ag Method for the production of proteins
BRPI0519626A2 (pt) * 2004-12-23 2009-02-25 Novo Nordisk Healthcare Ag mÉtodos para a reduÇço do teor de um ou mais contaminantes, do teor de proteÍna s em uma composiÇço, do teor de um ou mais contaminantes de proteÍna em um sobrenadante de cultura de cÉlula, do teor de proteÍna s em um sobrenadante de cultura de cÉlula, composiÇço compreendendo uma proteÍna dependente de vitamina k de interesse
DK1841863T3 (da) * 2005-01-14 2010-11-29 Bayer Healthcare Llc Fremgangsmåde til rensning af faktor VII
JP2008539208A (ja) * 2005-04-28 2008-11-13 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト 活性化型のｖｉｉ因子ポリペプチドを含んでいる閉鎖容器、調製する方法、並びにキットおよび前記キットを使用する方法
WO2007101681A1 (en) 2006-03-07 2007-09-13 Baxter International Inc Highly phosphorylated and sulfated recombinant factor ix
WO2008104372A1 (en) * 2007-02-28 2008-09-04 Baxter International Inc. Method for the purification of recombinant blood coagulation factor ix enriched in sulfated and/or phosphorylated molecules
US9896677B2 (en) 2010-01-18 2018-02-20 Novo Nordisk Health Care Ag Purification of blood coagulation factors
ES2790884T3 (es) 2010-04-29 2020-10-29 Baxalta GmbH Método de purificación para proteínas de unión a cationes divalentes sobre resina de intercambio aniónico
WO2012104339A1 (en) 2011-02-01 2012-08-09 Novo Nordisk A/S Purification of insulin
US9701710B2 (en) 2011-10-14 2017-07-11 Baxalta Incorporated Protein purification by anion exchange chromatography
LT2748179T (lt) * 2011-10-14 2022-04-11 Takeda Pharmaceutical Company Limited Baltymų gryninimas anijonų mainų chromatografija
WO2014140289A1 (en) * 2013-03-15 2014-09-18 Baxter International Inc. Purification method for vitamin k dependent proteins by anion exchange chromatography

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3101752A1 (de) * 1981-01-21 1982-08-26 Behringwerke Ag, 3550 Marburg "verfahren zur reinigung der blutgerinnungsfaktoren ii, vii, ix und/oder x und danach hergestellte praeparationen"
DE3877529T2 (de) * 1987-10-23 1996-11-07 Centre Regional De Transfusion Herstellung von hoch-gereingtem menschlichen Faktor IX sowie anderem Plasmaproteinkonzentrat und dessen therapeutische Verwendung.
US4981952A (en) * 1988-10-04 1991-01-01 Eli Lilly And Company Method for the purification of vitamin K-dependent proteins
AT395596B (de) * 1991-06-20 1993-01-25 Immuno Ag Verfahren zur herstellung von aktiviertem protein c

Also Published As

Publication number Publication date
JPH07258286A (ja) 1995-10-09
SK22695A3 (en) 1995-09-13
CZ290471B6 (cs) 2002-07-17
EP0669342B1 (de) 2001-09-05
CZ53995A3 (en) 1995-09-13
DK0669342T3 (da) 2001-11-12
FI116526B (fi) 2005-12-15
EP0669342A2 (de) 1995-08-30
FI950888A0 (fi) 1995-02-27
NO322372B1 (no) 2006-09-25
HU219828B (hu) 2001-08-28
CA2143510A1 (en) 1995-08-29
CA2143510C (en) 1999-12-21
ATE205218T1 (de) 2001-09-15
HU9500594D0 (en) 1995-04-28
NO950733L (no) 1995-08-29
EP0669342A3 (de) 1997-04-16
ES2161790T3 (es) 2001-12-16
HUT72844A (en) 1996-05-28
US5633350A (en) 1997-05-27
DE4406515C1 (de) 1995-10-19
FI950888A (fi) 1995-08-29

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