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NO924859L - INTERLEUKIN-6 MIXTURES, AND A METHOD OF PRODUCING THESE - Google Patents

INTERLEUKIN-6 MIXTURES, AND A METHOD OF PRODUCING THESE

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Publication number
NO924859L
NO924859L NO92924859A NO924859A NO924859L NO 924859 L NO924859 L NO 924859L NO 92924859 A NO92924859 A NO 92924859A NO 924859 A NO924859 A NO 924859A NO 924859 L NO924859 L NO 924859L
Authority
NO
Norway
Prior art keywords
human interleukin
mixtures
interleukin
sugar chains
producing
Prior art date
Application number
NO92924859A
Other languages
Norwegian (no)
Other versions
NO924859D0 (en
Inventor
Shingou Sakurai
Masanobu Naruto
Makoto Kihara
Keizo Hanada
Emiko Sano
Shigeru Ichikura
Jun Utsumi
Kazuo Hosoi
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/JP1992/000487 external-priority patent/WO1992018537A1/en
Application filed by Toray Industries filed Critical Toray Industries
Publication of NO924859D0 publication Critical patent/NO924859D0/en
Publication of NO924859L publication Critical patent/NO924859L/en

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Den foreliggende oppfinnelse vedrører blandinger inne- holdende humant interleukin-6 med sukkerkjeder, en fremgangs- måte for fremstilling av humant interleukin-6 ved at man dyrker celler i et medium inneholdende askorbinsyre eller et av dets derivater, og en fremgangsmåte for å rense en rå human interleukin-6 opplesning ved hjelp av kromatografi hvor man bruker et bærestoff med bundet heparin. Foreliggende oppfinnelse gjør det mulig å fremstille humane interleukin-6 blandinger med sukkerkjeder av høy kvali- tet, og hvor disse blandinger kan brukes som medisiner. Videre er det beskrevet en fremgangsmåte for masseproduksjon av humant interleukin-6.The present invention relates to mixtures containing human interleukin-6 with sugar chains, a process for preparing human interleukin-6 by culturing cells in a medium containing ascorbic acid or one of its derivatives, and a process for purifying a crude human interleukin-6 solution by chromatography using a carrier with bound heparin. The present invention makes it possible to prepare human interleukin-6 mixtures with high quality sugar chains, and where these mixtures can be used as medicines. Furthermore, a process for mass production of human interleukin-6 is described.

NO92924859A 1991-04-18 1992-12-15 INTERLEUKIN-6 MIXTURES, AND A METHOD OF PRODUCING THESE NO924859L (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP8660291 1991-04-18
JP8828491 1991-04-19
PCT/JP1992/000487 WO1992018537A1 (en) 1991-04-18 1992-04-17 Interleukin 6 composition and production thereof

Publications (2)

Publication Number Publication Date
NO924859D0 NO924859D0 (en) 1992-12-15
NO924859L true NO924859L (en) 1993-02-17

Family

ID=27305207

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92924859A NO924859L (en) 1991-04-18 1992-12-15 INTERLEUKIN-6 MIXTURES, AND A METHOD OF PRODUCING THESE

Country Status (1)

Country Link
NO (1) NO924859L (en)

Also Published As

Publication number Publication date
NO924859D0 (en) 1992-12-15

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