NO781586L - POLYEN COMPOUNDS. - Google Patents
POLYEN COMPOUNDS.Info
- Publication number
- NO781586L NO781586L NO781586A NO781586A NO781586L NO 781586 L NO781586 L NO 781586L NO 781586 A NO781586 A NO 781586A NO 781586 A NO781586 A NO 781586A NO 781586 L NO781586 L NO 781586L
- Authority
- NO
- Norway
- Prior art keywords
- polyen
- compounds
- polyen compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/38—Alcohols containing six-membered aromatic rings and other rings and having unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/40—Halogenated unsaturated alcohols
- C07C33/50—Halogenated unsaturated alcohols containing six-membered aromatic rings and other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/782—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic
- C07C49/792—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic containing rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5456—Arylalkanephosphonium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
LU77254A LU77254A1 (en) | 1977-05-04 | 1977-05-04 |
Publications (3)
Publication Number | Publication Date |
---|---|
NO781586L true NO781586L (en) | 1978-11-07 |
NO148290B NO148290B (en) | 1983-06-06 |
NO148290C NO148290C (en) | 1983-09-14 |
Family
ID=19728555
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO781586A NO148290C (en) | 1977-05-04 | 1978-05-03 | ANALOGY PROCEDURE FOR THE PREPARATION OF NEW THERAPEUTICALLY ACTIVE POLYENE COMPOUNDS |
Country Status (32)
Country | Link |
---|---|
US (1) | US4193931A (en) |
JP (1) | JPS53137940A (en) |
AR (1) | AR220704A1 (en) |
AT (1) | AT356647B (en) |
AU (1) | AU522598B2 (en) |
BE (1) | BE866651A (en) |
BR (1) | BR7802807A (en) |
CA (1) | CA1114830A (en) |
CH (2) | CH641755A5 (en) |
CS (1) | CS214853B2 (en) |
CU (1) | CU21105A (en) |
DE (1) | DE2819213A1 (en) |
DK (1) | DK155730C (en) |
ES (2) | ES469394A1 (en) |
FI (1) | FI66587C (en) |
FR (1) | FR2390428A1 (en) |
GB (2) | GB1600914A (en) |
GR (1) | GR74426B (en) |
HU (1) | HU183088B (en) |
IE (1) | IE46946B1 (en) |
IL (2) | IL54590A (en) |
IT (1) | IT1096278B (en) |
LU (1) | LU77254A1 (en) |
MC (1) | MC1193A1 (en) |
MY (1) | MY8500250A (en) |
NL (1) | NL7804773A (en) |
NO (1) | NO148290C (en) |
NZ (1) | NZ187114A (en) |
PH (1) | PH14216A (en) |
PT (1) | PT67988B (en) |
SE (1) | SE436644B (en) |
ZA (1) | ZA782415B (en) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4216312A (en) | 1978-08-24 | 1980-08-05 | Hoffmann-La Roche Inc. | Furyl substituted polyenes |
FI67386C (en) * | 1979-06-21 | 1985-03-11 | Hoffmann La Roche | FOERFARANDE FOER FRAMSTAELLNING AV NYA THERAPEUTIC EQUIPMENT |
CH651007A5 (en) * | 1982-06-24 | 1985-08-30 | Hoffmann La Roche | POLYEN CONNECTIONS. |
DK158947C (en) * | 1982-07-06 | 1991-01-21 | Hoffmann La Roche | TETRAHYDRONAPHTHALIN, BENZOFURAN AND BENZOTHIOPHENDER DERIVATIVES, PREPARATION AND USE THEREOF, AND RODENTICID CONTAINING SUCH DERIVATIVES |
US4529600A (en) * | 1982-09-09 | 1985-07-16 | Sri International | Pentadeuterioretinoids |
US4439614A (en) * | 1982-09-22 | 1984-03-27 | Sri International | 5,6-Methano-5,6-dihydroretinoids |
US4464389A (en) * | 1982-10-20 | 1984-08-07 | Sri International | Esters of retinoic acid and pentaerythritol and monobenzal acetals thereof |
US4539154A (en) * | 1983-06-15 | 1985-09-03 | Hoffmann-La Roche Inc. | Polyene compounds |
CH661516A5 (en) * | 1983-12-08 | 1987-07-31 | Hoffmann La Roche | PHENYLNONATETRAENOYL SUGAR DERIVATIVES. |
FR2569689B1 (en) * | 1984-09-05 | 1990-11-16 | Oreal | NOVEL BENZONORBORNENE DERIVATIVES, PREPARATION METHODS THEREOF, AND MEDICINAL AND COSMETIC COMPOSITIONS CONTAINING THEM |
FR2580277B1 (en) * | 1985-04-15 | 1988-06-10 | Oreal | NOVEL NAPHTHALENIC DERIVATIVES WITH RETINOIC ACTION, THEIR PREPARATION METHOD AND MEDICINAL AND COSMETIC COMPOSITIONS CONTAINING THEM |
US5030765A (en) * | 1986-05-23 | 1991-07-09 | Hoffmann-La Roche Inc. | Novel tetrahydronaphthalene and indane derivatives |
ZW7487A1 (en) * | 1986-05-23 | 1987-12-16 | Hoffmann La Roche | Tetrahydronaphthaline and indane derivatives |
US5030764A (en) * | 1986-05-23 | 1991-07-09 | Hoffmann-La Roche Inc. | Novel tetrahydronaphthalene and indane derivatives |
AT388728B (en) * | 1987-03-17 | 1989-08-25 | Hoffmann La Roche | NEW TETRAHYDRONAPHTHALINE AND INDANDERIVATIVES |
US5250562A (en) * | 1988-02-24 | 1993-10-05 | Hoffmann-La Roche Inc. | Stilbene derivatives |
US5248696A (en) * | 1991-04-18 | 1993-09-28 | World Research Institute For Science And Technology, Inc. | Composition and method for treating tumors |
US5780676A (en) * | 1992-04-22 | 1998-07-14 | Ligand Pharmaceuticals Incorporated | Compounds having selective activity for Retinoid X Receptors, and means for modulation of processes mediated by Retinoid X Receptors |
US7655699B1 (en) | 1992-04-22 | 2010-02-02 | Eisai Inc. | Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors |
CA2129773C (en) | 1993-09-02 | 2007-05-01 | Michael Klaus | Aromatic carboxylic acid derivatives |
FR2719041B1 (en) * | 1994-04-26 | 1996-05-31 | Cird Galderma | New polyene compounds, pharmaceutical and cosmetic compositions containing them and uses. |
DE69516903T2 (en) * | 1994-12-30 | 2000-10-26 | Ligand Pharmaceuticals, Inc. | RETINOID TRIENE CONNECTIONS AND METHOD |
US7115728B1 (en) * | 1995-01-30 | 2006-10-03 | Ligand Pharmaceutical Incorporated | Human peroxisome proliferator activated receptor γ |
DK0873295T3 (en) | 1995-10-06 | 2003-07-14 | Ligand Pharm Inc | Dimer selective RXR modulators and methods for their use |
US6112489A (en) * | 1995-12-12 | 2000-09-05 | Monotech International, Inc. | Monocoque concrete structures |
AU4080597A (en) * | 1996-08-23 | 1998-03-06 | Board Of Regents For Oklahoma State University, The | Heteroarotinoids-anticancer agents with receptor specificity and tgase activity |
FR2752837B1 (en) * | 1996-09-02 | 1999-11-12 | Cird Galderma | NOVEL HORMONAL RECEPTOR MODULATING COMPOUNDS, COMPOSITIONS COMPRISING SAME AND THEIR USE IN THERAPY |
US7098025B1 (en) | 1997-07-25 | 2006-08-29 | Ligand Pharmaceuticals Incorporated | Human peroxisome proliferator activated receptor gamma (pparγ) gene regulatory sequences and uses therefor |
FR2768731B1 (en) | 1997-09-25 | 1999-12-10 | Cird Galderma | UNSATURATED DERIVATIVES IN POSITION -4 OF 6-TERT-BUTYL-1,1- DIMETHYLINDANE AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS |
US6534545B1 (en) | 1997-09-25 | 2003-03-18 | Galderma Research & Development | Unsaturated derivatives at the 4-position of 6-tert-butyl-1,1-dimethylindane and their use in human and veterinary medicine and cosmetics |
EP1093362A1 (en) * | 1998-06-12 | 2001-04-25 | Ligand Pharmaceuticals Incorporated | Treatment of anti-estrogen resistant breast cancer using rxr modulators |
HUP0202814A3 (en) * | 1999-08-27 | 2003-11-28 | Ligand Pharmaceuticals Inc San | Androgen receptor modulator compounds and methods for their preparation and pharmaceutical compositions containing them and their use |
CA2378298A1 (en) | 1999-08-27 | 2001-03-08 | Lawrence G. Hamann | 8-substituted-6-trifluoromethyl-9-pyrido¬3,2-g|quinoline compounds as androgen receptor modulators |
US6566372B1 (en) * | 1999-08-27 | 2003-05-20 | Ligand Pharmaceuticals Incorporated | Bicyclic androgen and progesterone receptor modulator compounds and methods |
CO5200852A1 (en) * | 1999-09-14 | 2002-09-27 | Lilly Co Eli | RXR MODULATORS WITH IMPROVED CEPTORS X PHARMACOLOGICAL PROFILE OF RETINOIDS |
US7842727B2 (en) * | 2001-03-27 | 2010-11-30 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors |
US6495719B2 (en) | 2001-03-27 | 2002-12-17 | Circagen Pharmaceutical | Histone deacetylase inhibitors |
US7312247B2 (en) | 2001-03-27 | 2007-12-25 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors |
US8026280B2 (en) | 2001-03-27 | 2011-09-27 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors |
US6586460B1 (en) | 2001-04-02 | 2003-07-01 | The Board Of Regents For Oklahoma State University | Heteroarotinoids containing urea or thiourea linker |
CA2486303C (en) * | 2002-05-22 | 2013-04-30 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors based on alpha-ketoepoxide compounds |
JP2006508986A (en) * | 2002-11-20 | 2006-03-16 | エルラント ゲネ セラペウチクス エルエルシー | Treatment of lung cells with histone deacetylase inhibitors |
US9050310B2 (en) * | 2004-06-25 | 2015-06-09 | Minas Theodore Coroneo | Treatment of ocular lesions |
US20060160902A1 (en) * | 2004-11-08 | 2006-07-20 | Wiech Norbert L | Histone deacetylase inhibitors |
US20060204474A1 (en) * | 2005-02-25 | 2006-09-14 | Coroneo Minas T | Treatment of epithelial layer lesions |
WO2012076842A1 (en) * | 2010-12-09 | 2012-06-14 | University Of Durham | Synthetic retinoids for control of cell differentiation |
US11045441B2 (en) | 2015-10-13 | 2021-06-29 | Wisconsin Alumni Research Foundation | Use of retinoic acid and analogs thereof to treat central neural apneas |
MX2020003762A (en) * | 2017-09-28 | 2022-05-03 | Johnson & Johnson Consumer Inc | Cosmetic compositions and method of treating the skin. |
US11197841B2 (en) | 2019-07-23 | 2021-12-14 | Johnson & Johnson Surgical Vision, Inc. | Compositions and methods for treating the eye |
US10966948B2 (en) | 2019-07-23 | 2021-04-06 | Johnson & Johnson Surgical Vision, Inc. | Compositions and methods for treating the eye |
KR20210038636A (en) * | 2018-07-27 | 2021-04-07 | 존슨 앤드 존슨 서지컬 비전, 인코포레이티드 | Composition and method for eye treatment |
US11969454B2 (en) | 2019-11-19 | 2024-04-30 | Johnson & Johnson Surgical Vision, Inc. | Compositions and methods for treating the eye |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3452085A (en) * | 1966-02-11 | 1969-06-24 | Carbo Erba Spa | Alpha-(5-indanyl)-butyric acid |
US3781314A (en) * | 1971-07-14 | 1973-12-25 | Hoffmann La Roche | Polyene compounds |
BE793108A (en) * | 1971-12-22 | 1973-06-21 | Hoffmann La Roche | POLYENE DERIVATIVES |
US3957836A (en) * | 1973-07-02 | 1976-05-18 | Takeda Chemical Industries, Ltd. | Quinone derivatives |
CH582668A5 (en) * | 1973-08-10 | 1976-12-15 | Hoffmann La Roche | |
CH585709A5 (en) * | 1973-08-24 | 1977-03-15 | Hoffmann La Roche | |
CH592598A5 (en) * | 1973-10-30 | 1977-10-31 | Hexachimie | |
AR206620A1 (en) * | 1974-02-07 | 1976-08-06 | Hexachimie | PROCEDURE FOR PREPARING 5-INDANILACETIC ACIDS |
FR2276035A1 (en) * | 1974-06-28 | 1976-01-23 | Lipha | Substd-indane-5-carboxylic acids - with antiinflammatory, analgesic and antipyretic activity |
US4054589A (en) * | 1974-09-26 | 1977-10-18 | Hoffmann-La Roche Inc. | Novel 9-substituted phenyl-3,7-dimethyl-nona-2,4,6,8-tetraene esters |
JPS51125235A (en) * | 1974-09-26 | 1976-11-01 | Hoffmann La Roche | Preparation of polyene compounds |
-
1977
- 1977-05-04 LU LU77254A patent/LU77254A1/xx unknown
-
1978
- 1978-03-30 CH CH340578A patent/CH641755A5/en not_active IP Right Cessation
- 1978-04-13 CA CA301,052A patent/CA1114830A/en not_active Expired
- 1978-04-20 FI FI781227A patent/FI66587C/en not_active IP Right Cessation
- 1978-04-24 US US05/899,427 patent/US4193931A/en not_active Expired - Lifetime
- 1978-04-27 ZA ZA00782415A patent/ZA782415B/en unknown
- 1978-04-27 IL IL54590A patent/IL54590A/en unknown
- 1978-04-28 NZ NZ187714A patent/NZ187114A/en unknown
- 1978-05-01 IE IE864/78A patent/IE46946B1/en unknown
- 1978-05-02 JP JP5241878A patent/JPS53137940A/en active Granted
- 1978-05-02 FR FR7812933A patent/FR2390428A1/en active Granted
- 1978-05-02 MC MC781300A patent/MC1193A1/en unknown
- 1978-05-02 DE DE19782819213 patent/DE2819213A1/en active Granted
- 1978-05-03 PT PT67988A patent/PT67988B/en unknown
- 1978-05-03 ES ES469394A patent/ES469394A1/en not_active Expired
- 1978-05-03 SE SE7805136A patent/SE436644B/en not_active IP Right Cessation
- 1978-05-03 HU HU78HO2072A patent/HU183088B/en not_active IP Right Cessation
- 1978-05-03 GB GB17478/78A patent/GB1600914A/en not_active Expired
- 1978-05-03 DK DK195378A patent/DK155730C/en not_active IP Right Cessation
- 1978-05-03 PH PH21098A patent/PH14216A/en unknown
- 1978-05-03 AT AT320478A patent/AT356647B/en not_active IP Right Cessation
- 1978-05-03 BE BE187341A patent/BE866651A/en not_active IP Right Cessation
- 1978-05-03 GB GB5961/80A patent/GB1600915A/en not_active Expired
- 1978-05-03 NL NL7804773A patent/NL7804773A/en not_active Application Discontinuation
- 1978-05-03 NO NO781586A patent/NO148290C/en unknown
- 1978-05-04 CU CU7834913A patent/CU21105A/en unknown
- 1978-05-04 BR BR7802807A patent/BR7802807A/en unknown
- 1978-05-04 IT IT23003/78A patent/IT1096278B/en active
- 1978-05-04 CS CS782858A patent/CS214853B2/en unknown
- 1978-05-04 AR AR272036A patent/AR220704A1/en active
- 1978-05-04 GR GR56136A patent/GR74426B/el unknown
- 1978-05-04 AU AU35762/78A patent/AU522598B2/en not_active Expired
- 1978-11-20 ES ES475240A patent/ES475240A1/en not_active Expired
-
1980
- 1980-12-12 IL IL61697A patent/IL61697A0/en unknown
-
1983
- 1983-02-11 CH CH78683A patent/CH642380A5/en not_active IP Right Cessation
-
1985
- 1985-12-30 MY MY250/85A patent/MY8500250A/en unknown
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