NO20051108L - Cytotoksiske midler som inneholder nye virksomme taksaner og terapeutisk anvendelse av disse - Google Patents
Cytotoksiske midler som inneholder nye virksomme taksaner og terapeutisk anvendelse av disseInfo
- Publication number
- NO20051108L NO20051108L NO20051108A NO20051108A NO20051108L NO 20051108 L NO20051108 L NO 20051108L NO 20051108 A NO20051108 A NO 20051108A NO 20051108 A NO20051108 A NO 20051108A NO 20051108 L NO20051108 L NO 20051108L
- Authority
- NO
- Norway
- Prior art keywords
- taxanes
- binding agent
- therapeutic use
- cytotoxic agents
- agents containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Epoxy Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21011202A | 2002-08-02 | 2002-08-02 | |
US10/369,563 US7390898B2 (en) | 2002-08-02 | 2003-02-21 | Cytotoxic agents containing novel potent taxanes and their therapeutic use |
PCT/US2003/019558 WO2004013093A2 (en) | 2002-08-02 | 2003-07-14 | Cytotoxic agents containing novel potent taxanes and their therapeutic use |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20051108L true NO20051108L (no) | 2005-05-02 |
Family
ID=31498026
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20051108A NO20051108L (no) | 2002-08-02 | 2005-03-01 | Cytotoksiske midler som inneholder nye virksomme taksaner og terapeutisk anvendelse av disse |
Country Status (12)
Country | Link |
---|---|
US (2) | US7495114B2 (ko) |
EP (1) | EP1534674A4 (ko) |
JP (1) | JP2005539009A (ko) |
KR (1) | KR20050032110A (ko) |
CN (1) | CN100522955C (ko) |
AU (1) | AU2003247587B2 (ko) |
BR (1) | BR0313197A (ko) |
CA (1) | CA2494074A1 (ko) |
IL (1) | IL166624A0 (ko) |
MX (1) | MXPA05001390A (ko) |
NO (1) | NO20051108L (ko) |
WO (1) | WO2004013093A2 (ko) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100056762A1 (en) | 2001-05-11 | 2010-03-04 | Old Lloyd J | Specific binding proteins and uses thereof |
ATE446317T1 (de) | 2001-05-11 | 2009-11-15 | Ludwig Inst For Cancer Res Ltd | Spezifische bindungsproteine und ihre verwendung |
WO2005065121A2 (en) * | 2003-12-02 | 2005-07-21 | Cytimmune Sciences, Inc. | Methods and compositions for the production of monoclonal antibodies |
JP4833862B2 (ja) * | 2004-01-28 | 2011-12-07 | サイトイミューン サイエンシズ インコーポレイテッド | 官能化コロイド金属組成物および方法 |
NZ551622A (en) * | 2004-06-03 | 2010-01-29 | Smithkline Beecham Cork Ltd | Treatment of esophageal cancer with lapatinib tosylate |
EP1669358A1 (en) * | 2004-12-07 | 2006-06-14 | Aventis Pharma S.A. | Cytotoxic agents comprising new taxanes |
EP1688415A1 (en) * | 2004-12-07 | 2006-08-09 | Aventis Pharma S.A. | Cytotoxic agents comprising new C-2 modified taxanes |
EP1888121A2 (en) * | 2005-05-12 | 2008-02-20 | Tapestry Pharmaceuticals, Inc. | Anticancer targeted conjugates comprising a succinyl or glutaryl linker |
ZA200900545B (en) | 2006-07-18 | 2010-03-31 | Sanofi Aventis | Antagonist antibody against EPHA2 for the treatment of cancer |
WO2008091701A2 (en) * | 2007-01-25 | 2008-07-31 | Dana-Farber Cancer Institute | Use of anti-egfr antibodies in treatment of egfr mutant mediated disease |
AU2008227123B2 (en) * | 2007-03-15 | 2014-03-27 | Ludwig Institute For Cancer Research Ltd. | Treatment method using EGFR antibodies and src inhibitors and related formulations |
ES2609915T3 (es) | 2007-08-14 | 2017-04-25 | Ludwig Institute For Cancer Research Ltd. | Anticuerpo monoclonal 175 direccionado al receptor de EGF y derivados y usos del mismo |
JP2011520769A (ja) * | 2007-09-21 | 2011-07-21 | サイトイミューン サイエンシズ インコーポレイテッド | ナノ治療コロイド金属組成物および方法 |
US20110014118A1 (en) * | 2007-09-21 | 2011-01-20 | Lawrence Tamarkin | Nanotherapeutic colloidal metal compositions and methods |
US8558019B2 (en) * | 2007-11-08 | 2013-10-15 | Virginia Tech Intellectual Properties, Inc. | Thiolated paclitaxels for reaction with gold nanoparticles as drug delivery agents |
CN105198908B (zh) | 2009-02-05 | 2019-12-24 | 伊缪诺金公司 | 新型苯并二氮杂*衍生物 |
US20110076232A1 (en) * | 2009-09-29 | 2011-03-31 | Ludwig Institute For Cancer Research | Specific binding proteins and uses thereof |
EP2531173B1 (en) * | 2010-02-03 | 2018-09-26 | Oncbiomune, L.L.C. | Taxane- and taxoid-protein compositions |
RU2573994C2 (ru) | 2010-02-10 | 2016-01-27 | Иммьюноджен, Инк | Антитела против cd20 и их применение |
JP5826863B2 (ja) | 2011-02-15 | 2015-12-02 | イミュノジェン・インコーポレーテッド | 細胞傷害性ベンゾジアゼピン誘導体 |
EP2723389A2 (en) | 2011-06-21 | 2014-04-30 | Immunogen, Inc. | Novel maytansinoid derivatives with peptide linker and conjugates thereof |
US9353150B2 (en) | 2012-12-04 | 2016-05-31 | Massachusetts Institute Of Technology | Substituted pyrazino[1′,2′:1 ,5]pyrrolo[2,3-b]-indole-1,4-diones for cancer treatment |
US10208125B2 (en) | 2013-07-15 | 2019-02-19 | University of Pittsburgh—of the Commonwealth System of Higher Education | Anti-mucin 1 binding agents and uses thereof |
WO2015096553A1 (zh) * | 2013-12-24 | 2015-07-02 | 于跃 | 抗多药耐药紫杉烷类抗肿瘤化合物及其制备方法 |
US9943606B2 (en) | 2014-01-15 | 2018-04-17 | Rutgers, The State University Of New Jersey | Dendritic polypeptide-based nanocarriers for the delivery of therapeutic agents |
EP3189057A1 (en) | 2014-09-03 | 2017-07-12 | ImmunoGen, Inc. | Cytotoxic benzodiazepine derivatives |
EP3778601A1 (en) | 2014-09-03 | 2021-02-17 | ImmunoGen, Inc. | Cytotoxic benzodiazepine derivatives |
WO2016090157A1 (en) | 2014-12-04 | 2016-06-09 | Celgene Corporation | Biomolecule conjugates |
KR20180021176A (ko) | 2015-06-29 | 2018-02-28 | 이뮤노젠 아이엔씨 | 시스테인 조작된 항체의 콘주게이트 |
CN108055844A (zh) | 2015-07-21 | 2018-05-18 | 伊缪诺金公司 | 制备细胞毒性苯并二氮杂*衍生物的方法 |
WO2017091745A1 (en) | 2015-11-25 | 2017-06-01 | Immunogen, Inc. | Pharmaceutical formulations and methods of use thereof |
WO2017197045A1 (en) | 2016-05-11 | 2017-11-16 | Movassaghi Mohammad | Convergent and enantioselective total synthesis of communesin analogs |
US10287256B2 (en) | 2016-11-23 | 2019-05-14 | Immunogen, Inc. | Selective sulfonation of benzodiazepine derivatives |
WO2018160539A1 (en) | 2017-02-28 | 2018-09-07 | Immunogen, Inc. | Maytansinoid derivatives with self-immolative peptide linkers and conjugates thereof |
WO2018195243A1 (en) | 2017-04-20 | 2018-10-25 | Immunogen, Inc. | Cytotoxic benzodiazepine derivatives and conjugates thereof |
WO2018209239A1 (en) | 2017-05-11 | 2018-11-15 | Massachusetts Institute Of Technology | Potent agelastatin derivatives as modulators for cancer invasion and metastasis |
US10640508B2 (en) | 2017-10-13 | 2020-05-05 | Massachusetts Institute Of Technology | Diazene directed modular synthesis of compounds with quaternary carbon centers |
TW202413360A (zh) | 2017-12-28 | 2024-04-01 | 美商伊繆諾金公司 | 苯二氮平衍生物 |
WO2020191344A1 (en) | 2019-03-20 | 2020-09-24 | The Regents Of The University Of California | Claudin-6 bispecific antibodies |
BR112021018608A2 (pt) | 2019-03-20 | 2021-11-23 | Univ California | Anticorpos para claudina-6 e conjugados de fármaco |
JP2022529583A (ja) | 2019-03-29 | 2022-06-23 | イミュノジェン・インコーポレーテッド | 異常細胞増殖を阻害するまたは増殖性疾患を治療するための細胞毒性ビス-ベンゾジアゼピン誘導体及び細胞結合剤とのその複合体 |
PT3958977T (pt) | 2019-04-26 | 2023-12-15 | Immunogen Inc | Derivados de camptotecina |
US11535634B2 (en) | 2019-06-05 | 2022-12-27 | Massachusetts Institute Of Technology | Compounds, conjugates, and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines and uses thereof |
CA3168882A1 (en) | 2020-02-25 | 2021-09-02 | Mediboston, Inc. | Camptothecin derivatives and conjugates thereof |
CN116390772A (zh) | 2020-07-07 | 2023-07-04 | 博泰康医药公司 | 新型美登素类似物作为adc有效载荷及其在癌症治疗中的用途 |
US12030888B2 (en) | 2021-02-24 | 2024-07-09 | Massachusetts Institute Of Technology | Himastatin derivatives, and processes of preparation thereof, and uses thereof |
US20220378929A1 (en) | 2021-02-25 | 2022-12-01 | MediBoston Limted | Anti-her2 antibody-drug conjugates and uses thereof |
WO2024023735A1 (en) | 2022-07-27 | 2024-02-01 | Mediboston Limited | Auristatin derivatives and conjugates thereof |
Family Cites Families (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU631802B2 (en) | 1988-06-14 | 1992-12-10 | Cetus Oncology Corporation | Coupling agents and sterically hindered disulfide linked conjugates prepared therefrom |
US5208020A (en) | 1989-10-25 | 1993-05-04 | Immunogen Inc. | Cytotoxic agents comprising maytansinoids and their therapeutic use |
US5399726A (en) | 1993-01-29 | 1995-03-21 | Florida State University | Process for the preparation of baccatin III analogs bearing new C2 and C4 functional groups |
US5728725A (en) | 1991-09-23 | 1998-03-17 | Florida State University | C2 taxane derivaties and pharmaceutical compositions containing them |
US6028205A (en) | 1991-09-23 | 2000-02-22 | Florida State University | C2 tricyclic taxanes |
EP0563475B1 (en) | 1992-03-25 | 2000-05-31 | Immunogen Inc | Cell binding agent conjugates of derivatives of CC-1065 |
US5356928A (en) * | 1992-11-06 | 1994-10-18 | Hauser Chemical Research, Inc. | Cytotoxic agents |
US5646176A (en) * | 1992-12-24 | 1997-07-08 | Bristol-Myers Squibb Company | Phosphonooxymethyl ethers of taxane derivatives |
IL108443A0 (en) * | 1993-01-29 | 1994-04-12 | Univ Florida State | C7 taxane derivatives and pharmaceutical compositions containing them |
US6339164B1 (en) | 1993-01-29 | 2002-01-15 | Florida State University | C2 substituted phenyl taxane derivatives and pharmaceutical compositions containing them |
US5703247A (en) * | 1993-03-11 | 1997-12-30 | Virginia Tech Intellectual Properties, Inc. | 2-Debenzoyl-2-acyl taxol derivatives and methods for making same |
US5475011A (en) | 1993-03-26 | 1995-12-12 | The Research Foundation Of State University Of New York | Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment |
US6214345B1 (en) | 1993-05-14 | 2001-04-10 | Bristol-Myers Squibb Co. | Lysosomal enzyme-cleavable antitumor drug conjugates |
CA2129288C (en) * | 1993-08-17 | 2000-05-16 | Jerzy Golik | Phosphonooxymethyl esters of taxane derivatives |
US5824701A (en) | 1993-10-20 | 1998-10-20 | Enzon, Inc. | Taxane-based prodrugs |
AU4001295A (en) * | 1994-10-14 | 1996-05-06 | Hauser Chemical Research, Inc. | New cytotoxic agents |
WO1996023779A1 (fr) * | 1995-02-02 | 1996-08-08 | Daiichi Pharmaceutical Co., Ltd. | Derives ethers |
CN1211919A (zh) * | 1995-09-13 | 1999-03-24 | 佛罗里达州立大学 | 放射增敏性紫杉烷及其药物制剂 |
JP4172726B2 (ja) | 1996-05-22 | 2008-10-29 | ルイトポルド・ファーマシューティカルズ・インコーポレーテッド | シス―ドコサヘキサエン酸とドセタキセルとの共有複合体を含有する製剤 |
EP0941120A4 (en) | 1996-11-05 | 2004-08-18 | Bristol Myers Squibb Co | BRANCHED PEPTIDLINKERS |
US5811452A (en) | 1997-01-08 | 1998-09-22 | The Research Foundation Of State University Of New York | Taxoid reversal agents for drug-resistance in cancer chemotherapy and pharmaceutical compositions thereof |
WO1998052614A2 (en) | 1997-05-21 | 1998-11-26 | The Board Of Trustees Of The Leland Stanford Junior University | Composition and method for enhancing transport across biological membranes |
AU741433B2 (en) * | 1997-10-08 | 2001-11-29 | Bio Research Corporation Of Yokohama | Taxoid derivatives and process for producing the same |
AU1172599A (en) | 1997-11-18 | 1999-06-07 | Chugai Seiyaku Kabushiki Kaisha | Compounds with antitumor activity |
US6958212B1 (en) | 1999-02-01 | 2005-10-25 | Eidgenossische Technische Hochschule Zurich | Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds |
MXPA01008699A (es) * | 1999-02-24 | 2002-06-21 | Uab Research Foundation | Derivados de taxano para terapia de cancer dirigida. . |
NZ517772A (en) * | 1999-11-24 | 2004-03-26 | Immunogen Inc | Cytotoxic agents comprising taxanes and their therapeutic use |
US6175023B1 (en) | 2000-01-31 | 2001-01-16 | Jian Liu | Synthesis of water soluble 9-dihydro-paclitaxel derivatives from 9-dihydro-13-acetylbaccatin III |
MXPA01009923A (es) * | 2000-02-02 | 2003-08-01 | Univ Florida State Res Found | Taxanos sustituidos con carbamoiloxilo en c7 como agentes antitumorales. |
IL145639A (en) * | 2000-02-02 | 2007-02-11 | Univ Florida State Res Found | Cetro-converted Texanate acetate in C10 as anti-cancer agents |
MXPA01009906A (es) * | 2000-02-02 | 2003-07-28 | Univ Florida State Res Found | Taxanos sustituidos con carbonato en c7 como agentes. |
WO2001057013A1 (en) * | 2000-02-02 | 2001-08-09 | Florida State University Research Foundation, Inc. | Taxane formulations having improved solubility |
BR0104353A (pt) * | 2000-02-02 | 2002-04-16 | Univ Florida State Res Found | Taxanos heterosubstituìdos com acetato c7 como agentes antitumor |
US6596757B1 (en) | 2002-05-14 | 2003-07-22 | Immunogen Inc. | Cytotoxic agents comprising polyethylene glycol-containing taxanes and their therapeutic use |
-
2003
- 2003-07-14 CA CA002494074A patent/CA2494074A1/en not_active Abandoned
- 2003-07-14 EP EP03766820A patent/EP1534674A4/en not_active Withdrawn
- 2003-07-14 BR BR0313197-1A patent/BR0313197A/pt not_active IP Right Cessation
- 2003-07-14 CN CNB038232480A patent/CN100522955C/zh not_active Expired - Fee Related
- 2003-07-14 JP JP2004526000A patent/JP2005539009A/ja active Pending
- 2003-07-14 KR KR1020057001946A patent/KR20050032110A/ko not_active Application Discontinuation
- 2003-07-14 AU AU2003247587A patent/AU2003247587B2/en not_active Ceased
- 2003-07-14 MX MXPA05001390A patent/MXPA05001390A/es active IP Right Grant
- 2003-07-14 WO PCT/US2003/019558 patent/WO2004013093A2/en active Application Filing
-
2004
- 2004-08-26 US US10/926,192 patent/US7495114B2/en not_active Expired - Fee Related
- 2004-10-14 US US10/963,711 patent/US7414073B2/en not_active Expired - Fee Related
-
2005
- 2005-02-01 IL IL16662405A patent/IL166624A0/xx unknown
- 2005-03-01 NO NO20051108A patent/NO20051108L/no unknown
Also Published As
Publication number | Publication date |
---|---|
WO2004013093A3 (en) | 2004-07-01 |
CN1684948A (zh) | 2005-10-19 |
WO2004013093A2 (en) | 2004-02-12 |
US7495114B2 (en) | 2009-02-24 |
CN100522955C (zh) | 2009-08-05 |
JP2005539009A (ja) | 2005-12-22 |
AU2003247587A1 (en) | 2004-02-23 |
BR0313197A (pt) | 2005-08-09 |
MXPA05001390A (es) | 2005-07-29 |
IL166624A0 (en) | 2006-01-15 |
KR20050032110A (ko) | 2005-04-06 |
US20050085513A1 (en) | 2005-04-21 |
EP1534674A4 (en) | 2007-11-28 |
EP1534674A2 (en) | 2005-06-01 |
US7414073B2 (en) | 2008-08-19 |
US20050026997A1 (en) | 2005-02-03 |
AU2003247587B2 (en) | 2009-07-09 |
CA2494074A1 (en) | 2004-02-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20051108L (no) | Cytotoksiske midler som inneholder nye virksomme taksaner og terapeutisk anvendelse av disse | |
DK1242401T3 (da) | Cytotoksiske midler, der omfatter taxaner, og den terapeutiske anvendelse deraf | |
DK1242438T3 (da) | Cytotoksiske midler omfattende modificerede doxorubiciner og daunorubiciner og deres terapeutiske anvendelse | |
ECSP055635A (es) | Agentes citotoxicos que contienen taxanos potentes novedosos y su uso terapeutico | |
KR20030086596A (ko) | α,β불포화아릴 술폰을 이용한 이온화 방사선독성으로부터의 세포 및 조직 보호방법 | |
UY29875A1 (es) | Compuestos quimicos | |
CO4290417A1 (es) | Nuevas benzoilguanidinas como medicamentos y su preparacion . | |
UA86957C2 (ru) | Производные азепиноиндола в качестве фармацевтического средства | |
UY30736A1 (es) | Compuestos quimicos 537 | |
CY1107850T1 (el) | Παραγωγα θειαδιαζολυλοπιπεραζiνης mε χρησιμοτητα στην αποτροπη ή στην αγωγη εναντι tου αλγους | |
GEP20032869B (en) | Alpha -Ketoamide Inhibitors of 20S Proteasome, Pharmaceutical Preparations Containing the Same and Methods for Treatment | |
NO20070576L (no) | Nye hydantionderivater for behandling av obstruktive luftveissykdommer. | |
IL169896A0 (en) | Methods and compositions for administering therapeutic and diagnostic agents | |
NO952132L (no) | Farmakologiske aktive pyridin-derivater og deres fremstilling | |
MXPA02011304A (es) | Derivados de piperidina farmaceuticamente activos, en partiular como moduladores de la actividad del receptor de la quimocina. | |
NO20060971L (no) | Pyridazinderivater og deres anvendelse som terapeutiske midler | |
NO20072915L (no) | Farmasoytisk preparat som inneholder belagte magnetiske partikler og fremgangsmate for fremstilling av disse, og diagnoseterapisystem | |
WO2004076644A3 (en) | A composition for delivering an agent to a target cell and uses thereof | |
IS7965A (is) | Þíenópýrimidíndíón og notkun þeirra í breytingu ásjálfsnæmissjúkdómi | |
ATE302203T1 (de) | Pyrazolopyrimidin- und pyrazolotriazinderivate und diese enthaltende pharmazeutische zubereitungen | |
SE0302756D0 (sv) | Novel Compounds | |
AU2003255355A1 (en) | Progesterone receptor modulators having an increased antigonadotropic activity for use in female fertility testing and hormone replacement therapy | |
NO306400B1 (no) | N-substituerte azabicykloheptan-derivater, anvendelse derav og farmasöytisk preparat | |
NO20060561L (no) | Peparater inneholdende sertoliceller og myoidceller og anvendelse av disse i celletransplantater | |
DK1419240T3 (da) | Fremstilling og anvendelse af humane CD124- og CD116-positive tumorcellelinier til fremstilling af allogene eller semi-allogene immumterapeutika |