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NO20041964L - 4-[Piperidin-4-yliden-(3-karbamoylfenyl)metyl]benzamidderivater og deres anvendelse ved behandling av smerte, spinalskader og gastrointestinale forstyrrelser - Google Patents

4-[Piperidin-4-yliden-(3-karbamoylfenyl)metyl]benzamidderivater og deres anvendelse ved behandling av smerte, spinalskader og gastrointestinale forstyrrelser

Info

Publication number
NO20041964L
NO20041964L NO20041964A NO20041964A NO20041964L NO 20041964 L NO20041964 L NO 20041964L NO 20041964 A NO20041964 A NO 20041964A NO 20041964 A NO20041964 A NO 20041964A NO 20041964 L NO20041964 L NO 20041964L
Authority
NO
Norway
Prior art keywords
carbamoylphenyl
ylidene
piperidin
pain
methyl
Prior art date
Application number
NO20041964A
Other languages
English (en)
Norwegian (no)
Inventor
William Brown
Christopher Walpole
Zhongyong Wei
Original Assignee
Astrazeneca Ab Global Ip
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab Global Ip filed Critical Astrazeneca Ab Global Ip
Publication of NO20041964L publication Critical patent/NO20041964L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20041964A 2001-10-03 2004-04-27 4-[Piperidin-4-yliden-(3-karbamoylfenyl)metyl]benzamidderivater og deres anvendelse ved behandling av smerte, spinalskader og gastrointestinale forstyrrelser NO20041964L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0103313A SE0103313D0 (sv) 2001-10-03 2001-10-03 Novel compounds
PCT/SE2002/001804 WO2003029215A1 (en) 2001-10-03 2002-10-02 4[piperidin-4-yliden-(3-carbamoylphenyl)methyl] benzamide derivatives and their use for the treatment of pain, spinal injuries or gastrointestinal disorders

Publications (1)

Publication Number Publication Date
NO20041964L true NO20041964L (no) 2004-04-27

Family

ID=20285553

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20041964A NO20041964L (no) 2001-10-03 2004-04-27 4-[Piperidin-4-yliden-(3-karbamoylfenyl)metyl]benzamidderivater og deres anvendelse ved behandling av smerte, spinalskader og gastrointestinale forstyrrelser

Country Status (19)

Country Link
US (1) US7205317B2 (es)
EP (1) EP1440060A1 (es)
JP (1) JP2005505583A (es)
KR (1) KR20040039469A (es)
CN (1) CN1692100A (es)
AR (1) AR036649A1 (es)
BR (1) BR0212959A (es)
CA (1) CA2460168A1 (es)
CO (1) CO5580822A2 (es)
HU (1) HUP0401915A2 (es)
IL (1) IL160889A0 (es)
IS (1) IS7203A (es)
MX (1) MXPA04003056A (es)
NO (1) NO20041964L (es)
PL (1) PL368804A1 (es)
RU (1) RU2004107854A (es)
SE (1) SE0103313D0 (es)
WO (1) WO2003029215A1 (es)
ZA (1) ZA200402514B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR035974A1 (es) 2001-05-18 2004-07-28 Astrazeneca Ab Derivados de diarilmetil piperazina, procesos para su preparacion, uso de estos derivados para la elaboracion de medicamentos y composicion farmaceutica
SE0203303D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203302D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
MXPA05004916A (es) 2002-11-07 2005-08-18 Abbott Lab Protesis con multiples farmacos en gotas discretas no mezcladas.
SE0203300D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0301442D0 (sv) * 2003-05-16 2003-05-16 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations therof and uses thereof
BRPI0410347A (pt) * 2003-05-16 2006-05-30 Astrazeneca Ab composto, uso de um composto, composição farmacêutica, métodos para as terapias da dor e de distúrbios gostrointestinais funcionais em animal de sangue quente, e, processo para preparação de um composto
SE0301445D0 (sv) * 2003-05-16 2003-05-16 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
CA2530444C (en) * 2003-06-27 2012-03-13 Janssen Pharmaceutica, N.V. Tricyclic .delta. opioid modulators
NZ593444A (en) 2003-10-01 2012-12-21 Adolor Corp 4-[(2-N,N-diethylaminocarbonyl)pyrid-5-yl]-spiro[1,2-dihydronaphthalene-2,4'-piperidine] and methods of its use
US20100030183A1 (en) 2004-03-19 2010-02-04 Toner John L Method of treating vascular disease at a bifurcated vessel using a coated balloon
JP4949227B2 (ja) 2004-03-19 2012-06-06 アボット・ラボラトリーズ バルーンおよびプロテーゼからの多剤送達
DK1781631T3 (da) 2004-08-02 2012-05-14 Astrazeneca Ab Diarylmethylpiperazinderivater, præparater dermed og anvendelser deraf
US7598261B2 (en) 2005-03-31 2009-10-06 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
US7576207B2 (en) 2006-04-06 2009-08-18 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
CA2662115A1 (en) 2006-09-12 2008-03-20 Adolor Corporation Methods for enhancing cognitive function
LT3233825T (lt) * 2014-12-19 2020-08-10 Pharmnovo Ab Diarilmetilideno piperidino dariniai ir jų naudojimas kaip delta opioidinių receptorių agonistų
WO2016099394A1 (en) * 2014-12-19 2016-06-23 Pharmnovo Ab Novel selective delta-opioid receptor agonists useful for the treatment of pain, anxiety and depression.

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2898339A (en) * 1957-07-29 1959-08-04 Wm S Merrell Co N-substituted benzhydrol, benzhydryl, and benzhydrylidene piperidine
US4581171A (en) * 1983-07-27 1986-04-08 Janssen Pharmaceutica, N.V. [[Bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones useful for treating psychotropic disorders
US4816586A (en) * 1987-07-29 1989-03-28 Regents Of The University Of Minnesota Delta opioid receptor antagonists
US5140029A (en) * 1989-01-09 1992-08-18 Janssen Pharmaceutica N.V. 2-aminopyrimidinone derivatives
US4939137A (en) * 1989-06-28 1990-07-03 Ortho Pharmaceutical Corporation Ring-fused thienopyrimidinedione derivatives
US5683998A (en) * 1991-04-23 1997-11-04 Toray Industries, Inc. Tricyclic triazolo derivatives, processes for producing the same and the uses of the same
US5574159A (en) * 1992-02-03 1996-11-12 Delta Pharmaceuticals, Inc. Opioid compounds and methods for making therefor
GB9202238D0 (en) 1992-02-03 1992-03-18 Wellcome Found Compounds
SE9504661D0 (sv) 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
TW548271B (en) * 1996-12-20 2003-08-21 Astra Pharma Inc Novel piperidine derivatives having an exocyclic double bond with analgesic effects
WO1999033806A1 (en) 1997-12-24 1999-07-08 Ortho-Mcneil Pharmaceutical, Inc. 4-[aryl(piperidin-4-yl)] aminobenzamides which bind to the delta-opioid receptor
SE0001208D0 (sv) 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds
SE0001207D0 (sv) * 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds

Also Published As

Publication number Publication date
IL160889A0 (en) 2004-08-31
US7205317B2 (en) 2007-04-17
PL368804A1 (en) 2005-04-04
IS7203A (is) 2004-03-31
CA2460168A1 (en) 2003-04-10
US20050020629A1 (en) 2005-01-27
JP2005505583A (ja) 2005-02-24
EP1440060A1 (en) 2004-07-28
MXPA04003056A (es) 2004-07-05
CN1692100A (zh) 2005-11-02
RU2004107854A (ru) 2005-09-10
AR036649A1 (es) 2004-09-22
KR20040039469A (ko) 2004-05-10
SE0103313D0 (sv) 2001-10-03
BR0212959A (pt) 2004-10-13
WO2003029215A1 (en) 2003-04-10
HUP0401915A2 (hu) 2005-01-28
CO5580822A2 (es) 2005-11-30
ZA200402514B (en) 2005-01-24

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