NO20032227D0 - En laktoniseringsfremgangsmåte - Google Patents

En laktoniseringsfremgangsmåte

Info

Publication number: NO20032227D0
Authority: NO; Norway
Prior art keywords: lactonization method; lactonization
Prior art date: 2001-03-09

Application number

NO20032227A

Other languages

English (en)

Other versions

NO20032227L (no

Inventor

Frantisek Picha

Theodorus Hendricus Ant Peters

Jacobus Maria Lemmens

Original Assignee

Synthon Bv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-03-09

Filing date

2003-05-16

Publication date

2003-05-16

2003-05-16 Application filed by Synthon Bv filed Critical Synthon Bv

2003-05-16 Publication of NO20032227D0 publication Critical patent/NO20032227D0/no

2003-09-08 Publication of NO20032227L publication Critical patent/NO20032227L/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyrane Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

NO20032227A 2001-03-09 2003-05-16 En laktoniseringsfremgangsmåte NO20032227L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
NL1017548A NL1017548C2 (nl)	2001-03-09	2001-03-09	Een lactonisatie proces.
PCT/NL2002/000161 WO2002072566A1 (en)	2001-03-09	2002-03-11	A lactonization process

Publications (2)

Publication Number	Publication Date
NO20032227D0 true NO20032227D0 (no)	2003-05-16
NO20032227L NO20032227L (no)	2003-09-08

Family

ID=19773028

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20032227A NO20032227L (no)	2001-03-09	2003-05-16	En laktoniseringsfremgangsmåte

Country Status (7)

Country	Link
US (1)	US6562984B2 (no)
EP (1)	EP1368332A1 (no)
CN (1)	CN1476440A (no)
NL (1)	NL1017548C2 (no)
NO (1)	NO20032227L (no)
NZ (1)	NZ525972A (no)
WO (1)	WO2002072566A1 (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0218781D0 (en)	2002-08-13	2002-09-18	Astrazeneca Ab	Chemical process
GB0312896D0 (en)	2003-06-05	2003-07-09	Astrazeneca Ab	Chemical process
UY28501A1 (es)	2003-09-10	2005-04-29	Astrazeneca Uk Ltd	Compuestos químicos
GB0324791D0 (en)	2003-10-24	2003-11-26	Astrazeneca Ab	Chemical process
AU2004317826A1 (en) *	2004-03-30	2005-10-13	Lupin Ltd	An improved method for manufacture of 4-hydroxy pyran-2-one derivatives
AU2004323102A1 (en) *	2004-09-08	2006-03-16	Jubilant Organosys Limited	An improved process for lactonization in the preparation of statins
BRPI0519874A2 (pt) *	2005-02-04	2010-03-23	Lupin Ltd	processo aprimorado para a preparaÇço de um composto
CN101704808A (zh)	2009-11-20	2010-05-12	西南合成制药股份有限公司	制备他汀类化合物的内酯化方法
CN104098537A (zh) *	2009-11-20	2014-10-15	北大医药股份有限公司	制备他汀类化合物的内酯化方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4444784A (en)	1980-08-05	1984-04-24	Merck & Co., Inc.	Antihypercholesterolemic compounds
US4582915A (en)	1983-10-11	1986-04-15	Merck & Co., Inc.	Process for C-methylation of 2-methylbutyrates
US4855481A (en)	1984-11-19	1989-08-08	Merck Frosst Canada, Inc.	Process for the preparation of HMG-CoA reductase inhibitors and intermediate compounds employed therein
US4820850A (en)	1987-07-10	1989-04-11	Merck & Co., Inc.	Process for α-C-alkylation of the 8-acyl group on mevinolin and analogs thereof
US4916239A (en)	1988-07-19	1990-04-10	Merck & Co., Inc.	Process for the lactonization of mevinic acids and analogs thereof
US5223415A (en)	1990-10-15	1993-06-29	Merck & Co., Inc.	Biosynthetic production of 7-[1',2',6',7',8',8a'(R)-hexahydro-2'(S),6'(R)-dimethyl-8'(S)-hydroxy-1'(S)-naphthyl]-3(R),5(R)-dihydroxyheptanoic acid (triol acid)
US5159104A (en) *	1991-05-01	1992-10-27	Merck & Co., Inc.	Process to simvastatin ester
US5393893A (en)	1993-11-08	1995-02-28	Apotex, Inc.	Process for producing simvastatin and analogs thereof
CA2185961A1 (en)	1996-09-19	1998-03-20	K.S. Keshava Murthy	Process for producing simvastatin
NZ336993A (en)	1997-01-28	2000-05-26	Plus Chemicals Bv	Semi synthetic statins (simvastatin) derived from lovastatin
IN186879B (no)	1997-10-28	2001-12-01	Ranbaxy Lab Ltd
IN186880B (no)	1997-10-28	2001-12-01	Ranbaxy Lab Ltd
SI20070A (sl)	1998-09-18	2000-04-30	LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d.	Nove soli inhibitorjev HMG-CoA reduktaze
SI20527A (sl) *	1999-06-29	2001-10-31	Kaneka Corporation	Postopek za selektivno laktonizacijo
IN191580B (no) *	1999-12-17	2003-12-06	Ranbaxy Lab Ltd

2001
- 2001-03-09 NL NL1017548A patent/NL1017548C2/nl not_active IP Right Cessation
2002
- 2002-03-11 US US10/094,132 patent/US6562984B2/en not_active Expired - Fee Related
- 2002-03-11 WO PCT/NL2002/000161 patent/WO2002072566A1/en not_active Application Discontinuation
- 2002-03-11 CN CNA02803158XA patent/CN1476440A/zh active Pending
- 2002-03-11 EP EP02705606A patent/EP1368332A1/en not_active Withdrawn
- 2002-03-11 NZ NZ525972A patent/NZ525972A/en unknown
2003
- 2003-05-16 NO NO20032227A patent/NO20032227L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
WO2002072566A1 (en)	2002-09-19
CN1476440A (zh)	2004-02-18
US6562984B2 (en)	2003-05-13
NL1017548C2 (nl)	2002-09-10
NZ525972A (en)	2005-09-30
US20020147351A1 (en)	2002-10-10
EP1368332A1 (en)	2003-12-10
NO20032227L (no)	2003-09-08

Publication	Publication Date	Title
DE60205413D1 (de)	2005-09-15	Herstellungsverfahren
EE05587B1 (et)	2012-10-15	Meetod kollageenksna valmistamiseks
DE60203451D1 (de)	2005-05-04	Einschubschrank
DE60226131D1 (de)	2008-05-29	Strickverfahren
DE60103427D1 (de)	2004-06-24	Übereinstimmungssteuerverfahren
IL159175A0 (en)	2004-06-01	Patterning method
IS2523B (is)	2009-07-15	Turn vindorkuvers
ITMI20020092A0 (it)	2002-01-18	Un impianto
NO20032227D0 (no)	2003-05-16	En laktoniseringsfremgangsmåte
DE60226093D1 (de)	2008-05-29	Urmedium-Reinigungsmethode
DK1379128T3 (da)	2009-03-16	Planteinvigorator
DE50107729D1 (de)	2005-11-24	Regelverfahren
FI20011252A (fi)	2002-12-14	Rakennusmenetelmä
SE0104471D0 (sv)	2001-12-28	New method
FI20011169A0 (fi)	2001-06-04	Menetelmä petun modifioimiseksi
SE0100900D0 (sv)	2001-03-15	Method
DOP2001000312A (es)	2002-06-30	Metodo
SE0100899D0 (sv)	2001-03-15	Method
SE0102004L (sv)	2002-12-08	Indiviva-metoden
SE0101479D0 (sv)	2001-04-26	Method
NO20013389D0 (no)	2001-07-09	Kontrollmetode
SE0103416D0 (sv)	2001-10-12	New method
SE0103357D0 (sv)	2001-10-09	New method
SE0104227D0 (sv)	2001-12-14	New method
SE0103573D0 (sv)	2001-10-25	New method

Legal Events

Date	Code	Title	Description
2006-10-30	FC2A	Withdrawal, rejection or dismissal of laid open patent application