NO20024421D0 - Polyglutaminsyre-camptotecin-konjugater og fremgangsmåte for fremstilling av disse - Google Patents
Polyglutaminsyre-camptotecin-konjugater og fremgangsmåte for fremstilling av disseInfo
- Publication number
- NO20024421D0 NO20024421D0 NO20024421A NO20024421A NO20024421D0 NO 20024421 D0 NO20024421 D0 NO 20024421D0 NO 20024421 A NO20024421 A NO 20024421A NO 20024421 A NO20024421 A NO 20024421A NO 20024421 D0 NO20024421 D0 NO 20024421D0
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- polyglutamic acid
- camptothecin conjugates
- camptothecin
- conjugates
- Prior art date
Links
- 229940127093 camptothecin Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polyamides (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19042900P | 2000-03-17 | 2000-03-17 | |
| PCT/US2001/008553 WO2001070275A2 (en) | 2000-03-17 | 2001-03-19 | Polyglutamic acid-camptothecin conjugates and methods of preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20024421D0 true NO20024421D0 (no) | 2002-09-16 |
| NO20024421L NO20024421L (no) | 2002-11-15 |
Family
ID=22701317
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20024421A NO20024421L (no) | 2000-03-17 | 2002-09-16 | Polyglutaminsyre-camptothecin-konjugater og fremgangsmÕte for fremstilling av disse |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20020016285A1 (no) |
| EP (1) | EP1267939A2 (no) |
| JP (1) | JP2003527443A (no) |
| KR (1) | KR20020082888A (no) |
| CN (1) | CN1429121A (no) |
| AU (1) | AU2001247513A1 (no) |
| BR (1) | BR0109272A (no) |
| CA (1) | CA2402643A1 (no) |
| CZ (1) | CZ20023330A3 (no) |
| HU (1) | HUP0204562A2 (no) |
| IL (1) | IL151685A0 (no) |
| MX (1) | MXPA02009082A (no) |
| NO (1) | NO20024421L (no) |
| PL (1) | PL358335A1 (no) |
| RU (1) | RU2002128610A (no) |
| SI (1) | SI21172A (no) |
| SK (1) | SK14822002A3 (no) |
| TR (1) | TR200202194T2 (no) |
| WO (1) | WO2001070275A2 (no) |
| ZA (1) | ZA200207423B (no) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6441025B2 (en) | 1996-03-12 | 2002-08-27 | Pg-Txl Company, L.P. | Water soluble paclitaxel derivatives |
| US20030054977A1 (en) * | 1999-10-12 | 2003-03-20 | Cell Therapeutics, Inc. | Manufacture of polyglutamate-therapeutic agent conjugates |
| MXPA02003719A (es) | 1999-10-12 | 2002-08-30 | Cell Therapeutics Inc | Fabricacion de congujados de poliglutamato-agente terapeutico. |
| US20020077290A1 (en) * | 2000-03-17 | 2002-06-20 | Rama Bhatt | Polyglutamic acid-camptothecin conjugates and methods of preparation |
| US6629995B1 (en) * | 2000-03-31 | 2003-10-07 | Super Gen, Inc. | Camptothecin conjugates |
| DK1505973T3 (da) * | 2002-05-17 | 2010-05-31 | Celgene Corp | Kombinationer til behandling af multipelt myelom |
| USRE48890E1 (en) | 2002-05-17 | 2022-01-11 | Celgene Corporation | Methods for treating multiple myeloma with 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione after stem cell transplantation |
| US7968569B2 (en) | 2002-05-17 | 2011-06-28 | Celgene Corporation | Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione |
| US7393862B2 (en) | 2002-05-17 | 2008-07-01 | Celgene Corporation | Method using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for treatment of certain leukemias |
| US7323479B2 (en) | 2002-05-17 | 2008-01-29 | Celgene Corporation | Methods for treatment and management of brain cancer using 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-methylisoindoline |
| US11116782B2 (en) | 2002-10-15 | 2021-09-14 | Celgene Corporation | Methods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine |
| PT1580216E (pt) | 2002-10-31 | 2014-07-31 | Nippon Kayaku Kk | Derivados de elevado peso molecular de camptotecinas |
| AU2004233092C9 (en) * | 2003-04-17 | 2010-10-28 | Alnylam Pharmaceuticals, Inc. | Modified iRNA agents |
| US7851615B2 (en) * | 2003-04-17 | 2010-12-14 | Alnylam Pharmaceuticals, Inc. | Lipophilic conjugated iRNA agents |
| US8017762B2 (en) * | 2003-04-17 | 2011-09-13 | Alnylam Pharmaceuticals, Inc. | Modified iRNA agents |
| US8796436B2 (en) | 2003-04-17 | 2014-08-05 | Alnylam Pharmaceuticals, Inc. | Modified iRNA agents |
| US7723509B2 (en) | 2003-04-17 | 2010-05-25 | Alnylam Pharmaceuticals | IRNA agents with biocleavable tethers |
| UA83504C2 (en) | 2003-09-04 | 2008-07-25 | Селджин Корпорейшн | Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione |
| KR20070008710A (ko) | 2004-04-27 | 2007-01-17 | 웰스테트 바이올로직스 코포레이션 | 바이러스 및 캄토테신을 이용한 암치료 방법 |
| US8614228B2 (en) | 2004-08-11 | 2013-12-24 | Arqule, Inc. | Quinone prodrug compositions and methods of use |
| WO2006020722A2 (en) | 2004-08-11 | 2006-02-23 | Arqule, Inc. | Polymer conjugates of beta-lapachone and beta-lapachone analogs for tumor targeting |
| RU2375384C2 (ru) | 2004-09-22 | 2009-12-10 | Ниппон Каяку Кабусики Кайся | Новый блок-сополимер, мицеллярный препарат и противораковое средство, включающее мицеллярный препарат в качестве активного ингредиента |
| ATE540698T1 (de) | 2005-07-14 | 2012-01-15 | Wellstat Biologics Corp | Krebsbehandlung mit viren, fluoropyrimidinen und camptothecinen |
| ITPD20050242A1 (it) * | 2005-08-03 | 2007-02-04 | Fidia Farmaceutici | Bioconiugati antitumorali dell'acido ialuronico o dei suoi derivati, ottenibili per coniugazione chimica diretta o indiretta, e loro impiego in campo farmaceutico |
| CN101321806B (zh) | 2005-12-05 | 2011-01-26 | 日东电工株式会社 | 聚谷氨酸盐-氨基酸轭合物及方法 |
| US7671067B2 (en) * | 2006-02-09 | 2010-03-02 | Enzon Pharmaceuticals, Inc. | Treatment of non-hodgkin's lymphomas with multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamtothecin |
| US7462627B2 (en) * | 2006-02-09 | 2008-12-09 | Enzon Pharmaceuticals, Inc. | Multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin for treatment of breast, colorectal, pancreatic, ovarian and lung cancers |
| WO2007111211A1 (ja) | 2006-03-28 | 2007-10-04 | Nippon Kayaku Kabushiki Kaisha | タキサン類の高分子結合体 |
| JP5313867B2 (ja) | 2006-03-30 | 2013-10-09 | ドライス ファーマシューティカルズ，インコーポレイティド | カンプトテシン−細胞透過性ペプチド複合体及びそれを含む医薬組成物 |
| RU2447095C2 (ru) | 2006-05-18 | 2012-04-10 | Ниппон Каяку Кабусики Кайся | Высокомолекулярный конъюгат подофиллотоксинов |
| CL2007002218A1 (es) | 2006-08-03 | 2008-03-14 | Celgene Corp Soc Organizada Ba | Uso de 3-(4-amino-1-oxo-1,3-dihidro-isoindol-2-il)-piperidina 2,6-diona para la preparacion de un medicamento util para el tratamiento de linfoma de celula de capa. |
| US20090239782A1 (en) * | 2006-10-03 | 2009-09-24 | Masaharu Nakamura | High-molecular weight conjugate of resorcinol derivatives |
| JP5503872B2 (ja) | 2006-11-06 | 2014-05-28 | 日本化薬株式会社 | 核酸系代謝拮抗剤の高分子誘導体 |
| WO2008056654A1 (en) * | 2006-11-08 | 2008-05-15 | Nippon Kayaku Kabushiki Kaisha | Polymeric derivative of nucleic acid metabolic antagonist |
| US20080181852A1 (en) * | 2007-01-29 | 2008-07-31 | Nitto Denko Corporation | Multi-functional Drug Carriers |
| BRPI0807232A2 (pt) * | 2007-02-09 | 2014-04-29 | Enzon Pharmaceuticals Inc | Tratamento de cânceres resistentes ou refratários com conjugados poliméricos multi-braços de 7-etil-10-hidroxicamptotecina |
| CN101674852A (zh) * | 2007-04-10 | 2010-03-17 | 日东电工株式会社 | 多功能聚谷氨酸盐药物载体 |
| MX2009011822A (es) | 2007-04-30 | 2010-01-14 | Arqule Inc | Hidroxi sulfonatos de compuestos de quinonicos y sus usos. |
| WO2008141110A2 (en) * | 2007-05-09 | 2008-11-20 | Nitto Denko Corporation | Polyglutamate conjugates and polyglutamate-amino acid conjugates having a plurality of drugs |
| EP2155254B1 (en) * | 2007-05-09 | 2012-11-28 | Nitto Denko Corporation | Polymers conjugated with platinum drugs |
| ES2430380T3 (es) | 2007-05-09 | 2013-11-20 | Nitto Denko Corporation | Composiciones que incluyen un compuesto hidrófobo y un conjugado de poliaminoácido |
| JP5349318B2 (ja) | 2007-09-28 | 2013-11-20 | 日本化薬株式会社 | ステロイド類の高分子結合体 |
| CA2716662A1 (en) * | 2008-03-06 | 2009-03-11 | Nitto Denko Corporation | Polymer paclitaxel conjugates and methods for treating cancer |
| JP5687899B2 (ja) | 2008-03-18 | 2015-03-25 | 日本化薬株式会社 | 生理活性物質の高分子結合体 |
| WO2009136572A1 (ja) | 2008-05-08 | 2009-11-12 | 日本化薬株式会社 | 葉酸若しくは葉酸誘導体の高分子結合体 |
| JP2011162569A (ja) | 2008-05-23 | 2011-08-25 | Nano Career Kk | カンプトテシン高分子誘導体及びその用途 |
| TW201010732A (en) * | 2008-08-29 | 2010-03-16 | Enzon Pharmaceuticals Inc | Method of treating RAS associated cancer |
| RU2011117935A (ru) * | 2008-10-15 | 2012-11-27 | Нитто Денко Корпорейшн | Способ получения конъюгатов полиглутаматов |
| AU2009307922A1 (en) * | 2008-10-21 | 2010-04-29 | Enzon Pharmaceuticals, Inc. | Treatment of neuroblastoma with multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin |
| US8808749B2 (en) | 2009-05-15 | 2014-08-19 | Nippon Kayaku Kabushiki Kaisha | Polymer conjugate of bioactive substance having hydroxy group |
| KR20120094061A (ko) * | 2009-12-16 | 2012-08-23 | 닛토덴코 가부시키가이샤 | 폴리글루탐산의 제어된 합성법 |
| MX2012010448A (es) * | 2010-03-11 | 2012-12-05 | Nitto Denko Corp | Conjugados de carbohidrato-poli aminoacido-farmaco. |
| WO2011123813A2 (en) | 2010-04-02 | 2011-10-06 | Amunix Operating Inc. | Binding fusion proteins, binding fusion protein-drug conjugates, xten-drug conjugates and methods of making and using same |
| CA2816997A1 (en) | 2010-11-17 | 2012-05-24 | Nippon Kayaku Kabushiki Kaisha | Novel polymer derivative of cytidine metabolic antagonist |
| CN102649810A (zh) * | 2011-05-19 | 2012-08-29 | 东北林业大学 | 喜树碱衍生物、其制备方法和用途 |
| BR112014005452B1 (pt) | 2011-09-11 | 2021-03-16 | Nippon Kayaku Kabushiki Kaisha | método de produção de copolímero de bloco |
| US9180203B2 (en) * | 2012-10-23 | 2015-11-10 | The Johns Hopkins University | Self-assembling drug amphiphiles and methods for synthesis and use |
| PL3182996T3 (pl) | 2014-08-22 | 2023-04-17 | Celgene Corporation | Sposoby leczenia szpiczaka mnogiego związkami immunomodulującymi w kombinacji z przeciwciałami |
| ES2970117T3 (es) | 2015-06-26 | 2024-05-27 | Celgene Corp | Métodos para el tratamiento de sarcoma de Kaposi o linfoma inducido por KSHV usando compuestos inmunomoduladores, y usos de biomarcadores |
| CN106267227A (zh) * | 2016-08-12 | 2017-01-04 | 北京蓝贝望生物医药科技股份有限公司 | 抗肿瘤药物 |
| JP2019532104A (ja) * | 2016-09-30 | 2019-11-07 | アイエフセブンキュアー, インコーポレイテッドIf7Cure, Inc | 腫瘍血管系を標的とする抗腫瘍剤の製造方法 |
| CN106831853B (zh) * | 2017-02-15 | 2019-02-22 | 浙江海正药业股份有限公司 | 7-乙基-10-o-叔丁基二苯基硅基喜树碱-20-o-甘氨酸盐酸盐的制备工艺 |
| CN108727581A (zh) * | 2017-04-18 | 2018-11-02 | 华东师范大学 | 以苯硼酸酯为连接单元的两亲性喜树碱高分子前药及其制备方法和应用 |
| JP2021095424A (ja) * | 2018-03-28 | 2021-06-24 | 持田製薬株式会社 | 抗癌剤結合アルギン酸誘導体 |
| CN115298189B (zh) | 2019-12-04 | 2024-08-30 | 丹塔里股份有限公司 | 合成治疗性纳米颗粒的方法和组合物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4356166A (en) * | 1978-12-08 | 1982-10-26 | University Of Utah | Time-release chemical delivery system |
| US6441025B2 (en) * | 1996-03-12 | 2002-08-27 | Pg-Txl Company, L.P. | Water soluble paclitaxel derivatives |
| WO1997033552A1 (en) * | 1996-03-12 | 1997-09-18 | Pg-Txl Company, L.P. | Water soluble paclitaxel prodrugs |
-
2001
- 2001-03-19 HU HU0204562A patent/HUP0204562A2/hu unknown
- 2001-03-19 PL PL01358335A patent/PL358335A1/xx not_active Application Discontinuation
- 2001-03-19 US US09/810,345 patent/US20020016285A1/en not_active Abandoned
- 2001-03-19 KR KR1020027012206A patent/KR20020082888A/ko not_active Application Discontinuation
- 2001-03-19 CZ CZ20023330A patent/CZ20023330A3/cs unknown
- 2001-03-19 SI SI200120021A patent/SI21172A/sl not_active IP Right Cessation
- 2001-03-19 CN CN01809441A patent/CN1429121A/zh active Pending
- 2001-03-19 MX MXPA02009082A patent/MXPA02009082A/es unknown
- 2001-03-19 WO PCT/US2001/008553 patent/WO2001070275A2/en not_active Application Discontinuation
- 2001-03-19 TR TR2002/02194T patent/TR200202194T2/xx unknown
- 2001-03-19 BR BR0109272-3A patent/BR0109272A/pt active Pending
- 2001-03-19 RU RU2002128610/15A patent/RU2002128610A/ru unknown
- 2001-03-19 JP JP2001568471A patent/JP2003527443A/ja not_active Withdrawn
- 2001-03-19 AU AU2001247513A patent/AU2001247513A1/en not_active Abandoned
- 2001-03-19 SK SK1482-2002A patent/SK14822002A3/sk unknown
- 2001-03-19 EP EP01920466A patent/EP1267939A2/en not_active Withdrawn
- 2001-03-19 CA CA002402643A patent/CA2402643A1/en not_active Abandoned
- 2001-03-19 IL IL15168501A patent/IL151685A0/xx unknown
-
2002
- 2002-09-16 ZA ZA200207423A patent/ZA200207423B/en unknown
- 2002-09-16 NO NO20024421A patent/NO20024421L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| SI21172A (sl) | 2003-10-31 |
| ZA200207423B (en) | 2003-12-17 |
| RU2002128610A (ru) | 2004-03-27 |
| CN1429121A (zh) | 2003-07-09 |
| KR20020082888A (ko) | 2002-10-31 |
| SK14822002A3 (sk) | 2003-05-02 |
| AU2001247513A1 (en) | 2001-10-03 |
| IL151685A0 (en) | 2003-04-10 |
| NO20024421L (no) | 2002-11-15 |
| MXPA02009082A (es) | 2003-12-11 |
| US20020016285A1 (en) | 2002-02-07 |
| WO2001070275A2 (en) | 2001-09-27 |
| PL358335A1 (en) | 2004-08-09 |
| CZ20023330A3 (cs) | 2003-02-12 |
| BR0109272A (pt) | 2004-06-29 |
| EP1267939A2 (en) | 2003-01-02 |
| HUP0204562A2 (hu) | 2003-04-28 |
| WO2001070275A3 (en) | 2002-01-03 |
| CA2402643A1 (en) | 2001-09-27 |
| TR200202194T2 (tr) | 2003-01-21 |
| JP2003527443A (ja) | 2003-09-16 |
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