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NO20023149L - Fenylpiperazinylderivater - Google Patents

Fenylpiperazinylderivater

Info

Publication number
NO20023149L
NO20023149L NO20023149A NO20023149A NO20023149L NO 20023149 L NO20023149 L NO 20023149L NO 20023149 A NO20023149 A NO 20023149A NO 20023149 A NO20023149 A NO 20023149A NO 20023149 L NO20023149 L NO 20023149L
Authority
NO
Norway
Prior art keywords
phenylpiperazinyl
Prior art date
Application number
NO20023149A
Other languages
English (en)
Other versions
NO20023149D0 (no
Inventor
Thomas Ruhland
Jan Kehler
Kim Andersen
Benny Bang-Andersen
Mario Rottlaender
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of NO20023149L publication Critical patent/NO20023149L/no
Publication of NO20023149D0 publication Critical patent/NO20023149D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
NO20023149A 1999-12-30 2002-06-28 Fenylpiperazinylderivater NO20023149D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA199901886 1999-12-30
PCT/DK2000/000720 WO2001049677A1 (en) 1999-12-30 2000-12-20 Phenylpiperazinyl derivatives

Publications (2)

Publication Number Publication Date
NO20023149L true NO20023149L (no) 2002-06-28
NO20023149D0 NO20023149D0 (no) 2002-06-28

Family

ID=8108810

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20023149A NO20023149D0 (no) 1999-12-30 2002-06-28 Fenylpiperazinylderivater

Country Status (24)

Country Link
US (1) US20030083336A1 (no)
EP (1) EP1246815B1 (no)
JP (1) JP2003519223A (no)
KR (1) KR20020067589A (no)
CN (1) CN1437596A (no)
AR (1) AR029217A1 (no)
AT (1) ATE261958T1 (no)
AU (1) AU2152001A (no)
BG (1) BG106961A (no)
BR (1) BR0016951A (no)
CA (1) CA2395867A1 (no)
DE (1) DE60009154D1 (no)
EA (1) EA200200731A1 (no)
HU (1) HUP0203645A3 (no)
IL (1) IL150337A0 (no)
IS (1) IS6431A (no)
MX (1) MXPA02006499A (no)
NO (1) NO20023149D0 (no)
NZ (1) NZ519692A (no)
PL (1) PL355540A1 (no)
SK (1) SK11062002A3 (no)
TR (1) TR200201684T2 (no)
WO (1) WO2001049677A1 (no)
ZA (1) ZA200204970B (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040002488A1 (en) * 2002-05-29 2004-01-01 Cowart Marlon D. Fused bicyclic aromatic compounds that are useful in treating sexual dysfunction
EP1927594A1 (en) * 2003-01-14 2008-06-04 Arena Pharmaceuticals, Inc. 1,2,3-Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
AU2004205642C1 (en) * 2003-01-14 2012-01-12 Arena Pharmaceuticals, Inc. 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
WO2005061455A1 (en) 2003-12-23 2005-07-07 H. Lundbeck A/S 2-(1h-indolylsulfanyl)-benzyl amine derivatives as ssri
AR052308A1 (es) 2004-07-16 2007-03-14 Lundbeck & Co As H Derivados de 2-(1h-indolilsulfanil)-arilamina y una composicion farmaceutica que contiene al compuesto
EP1836192A2 (en) * 2005-01-03 2007-09-26 Universita' Degli Studi di Siena Aryl piperazine derivatives for the treatment of neuropsychiatric disorders
US7629473B2 (en) 2005-06-17 2009-12-08 H. Lundbeck A/S 2-(1H-indolylsulfanyl)-aryl amine derivatives
KR100868353B1 (ko) * 2007-03-08 2008-11-12 한국화학연구원 도파민 d4 수용체 길항제인 신규 피페라지닐프로필피라졸유도체, 이의 제조방법 및 이를 포함하는 약학적 조성물
CA2812061A1 (en) 2010-09-22 2012-03-29 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
CN104725359B (zh) 2013-12-20 2017-05-03 广东东阳光药业有限公司 取代的哌嗪化合物及其使用方法和用途
WO2015169180A1 (en) * 2014-05-04 2015-11-12 Sunshine Lake Pharma Co., Ltd. Substituted piperazine compounds and methods and use thereof
CN105085491B (zh) * 2014-05-05 2019-06-25 广东东阳光药业有限公司 取代的吲哚化合物及其使用方法和用途
GB201416352D0 (en) 2014-09-16 2014-10-29 Shire Internat Gmbh Spirocyclic derivatives
GB201416351D0 (en) 2014-09-16 2014-10-29 Shire Internat Gmbh Heterocyclic derivatives
CN105732591B (zh) * 2014-12-31 2019-10-25 广东东阳光药业有限公司 取代的哌嗪化合物及其使用方法和用途
WO2016112075A1 (en) 2015-01-06 2016-07-14 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the s1p1 receptor
AU2016284162A1 (en) 2015-06-22 2018-02-01 Arena Pharmaceuticals, Inc. Crystalline L-arginine salt of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid(Compound1) for use in SIP1 receptor-associated disorders
WO2017012579A1 (zh) * 2015-07-23 2017-01-26 广东东阳光药业有限公司 取代的吲哚化合物及其使用方法和用途
WO2017025058A1 (zh) * 2015-08-13 2017-02-16 广东东阳光药业有限公司 取代的吲哚化合物及其使用方法和用途
WO2018151873A1 (en) 2017-02-16 2018-08-23 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of primary biliary cholangitis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8830312D0 (en) * 1988-12-28 1989-02-22 Lundbeck & Co As H Heterocyclic compounds
GB9305623D0 (en) * 1993-03-18 1993-05-05 Merck Sharp & Dohme Therapeutic agents
GB9306578D0 (en) * 1993-03-30 1993-05-26 Merck Sharp & Dohme Therapeutic agents
WO1994024105A1 (en) * 1993-04-15 1994-10-27 Merck Sharp & Dohme Limited Indole derivatives as dopamine d4 antagonists
CA2188949A1 (en) * 1994-04-28 1995-11-09 Janusz Jozef Kulagowski Benzofuran derivatives as d4 receptor antagonists
PT775118E (pt) * 1994-08-05 2003-10-31 Pfizer Derivados de benzimidazole com actividade dopaminergica
USH2007H1 (en) * 1996-01-19 2001-12-04 Fmc Corporation Insecticidal N-heterocyclylalkyl-or N-[(polycyclyl)alkyl]-N′substituted piperazines

Also Published As

Publication number Publication date
HUP0203645A2 (hu) 2003-02-28
BR0016951A (pt) 2003-02-25
NZ519692A (en) 2004-05-28
AR029217A1 (es) 2003-06-18
PL355540A1 (en) 2004-05-04
SK11062002A3 (sk) 2002-12-03
IL150337A0 (en) 2002-12-01
WO2001049677A1 (en) 2001-07-12
ZA200204970B (en) 2004-01-26
EA200200731A1 (ru) 2002-12-26
EP1246815B1 (en) 2004-03-17
MXPA02006499A (es) 2002-11-29
AU2152001A (en) 2001-07-16
ATE261958T1 (de) 2004-04-15
US20030083336A1 (en) 2003-05-01
NO20023149D0 (no) 2002-06-28
BG106961A (en) 2003-04-30
CN1437596A (zh) 2003-08-20
HUP0203645A3 (en) 2004-01-28
KR20020067589A (ko) 2002-08-22
TR200201684T2 (tr) 2002-10-21
CA2395867A1 (en) 2001-07-12
JP2003519223A (ja) 2003-06-17
DE60009154D1 (de) 2004-04-22
IS6431A (is) 2002-06-19
EP1246815A1 (en) 2002-10-09

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application