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NO20013072L - Nitrogenholdige heterocykler som faktor Xa-inhibitorer - Google Patents

Nitrogenholdige heterocykler som faktor Xa-inhibitorer

Info

Publication number
NO20013072L
NO20013072L NO20013072A NO20013072A NO20013072L NO 20013072 L NO20013072 L NO 20013072L NO 20013072 A NO20013072 A NO 20013072A NO 20013072 A NO20013072 A NO 20013072A NO 20013072 L NO20013072 L NO 20013072L
Authority
NO
Norway
Prior art keywords
inhibitors
nitrogen
factor
containing heterocycles
heterocycles
Prior art date
Application number
NO20013072A
Other languages
English (en)
Other versions
NO20013072D0 (no
NO319816B1 (no
Inventor
John Matthew Fevig
Joseph Cacciola
Charles G Clark
Patrick Yuk-Sun Lam
Donald J P Pinto
James Russell Pruitt
Karen Anita Rossi
Qui Han
Mimi Lifen Quan
Original Assignee
Du Pont Pharm Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26811284&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20013072(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Du Pont Pharm Co filed Critical Du Pont Pharm Co
Publication of NO20013072D0 publication Critical patent/NO20013072D0/no
Publication of NO20013072L publication Critical patent/NO20013072L/no
Publication of NO319816B1 publication Critical patent/NO319816B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO20013072A 1998-12-23 2001-06-20 Nitrogenholdige heterocykler,anvendelse av disse for fremstilling av medikamenter samt farmasoytiske preparater. NO319816B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11362898P 1998-12-23 1998-12-23
US12763399P 1999-04-02 1999-04-02
PCT/US1999/030316 WO2000039131A1 (en) 1998-12-23 1999-12-17 Nitrogen containing heterobicycles as factor xa inhibitors

Publications (3)

Publication Number Publication Date
NO20013072D0 NO20013072D0 (no) 2001-06-20
NO20013072L true NO20013072L (no) 2001-06-20
NO319816B1 NO319816B1 (no) 2005-09-19

Family

ID=26811284

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20013072A NO319816B1 (no) 1998-12-23 2001-06-20 Nitrogenholdige heterocykler,anvendelse av disse for fremstilling av medikamenter samt farmasoytiske preparater.

Country Status (26)

Country Link
US (2) US6413980B1 (no)
EP (1) EP1140941B1 (no)
JP (1) JP2002533465A (no)
KR (1) KR100628407B1 (no)
CN (1) CN100340559C (no)
AR (1) AR024242A1 (no)
AT (1) ATE280171T1 (no)
AU (1) AU759711B2 (no)
BR (1) BR9917080A (no)
CA (1) CA2349330C (no)
DE (1) DE69921358T2 (no)
DK (1) DK1140941T3 (no)
EA (1) EA004515B1 (no)
ES (1) ES2232202T3 (no)
HK (1) HK1052508B (no)
HR (1) HRP990396A2 (no)
IL (2) IL142959A0 (no)
MX (1) MXPA01006502A (no)
MY (1) MY138239A (no)
NO (1) NO319816B1 (no)
NZ (1) NZ511674A (no)
PT (1) PT1140941E (no)
SI (1) SI1140941T1 (no)
TW (1) TWI225862B (no)
WO (1) WO2000039131A1 (no)
ZA (1) ZA200103795B (no)

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US20040077605A1 (en) * 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
EP1854798A3 (en) 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US6960595B2 (en) * 2001-03-23 2005-11-01 Bristol-Myers Squibb Pharma Company 5-6 to 5-7 Heterobicycles as factor Xa inhibitors
US6706730B2 (en) 2001-04-18 2004-03-16 Bristol-Myers Squibb Pharma Company 1,4,5,6-tetrahydropyrazolo-[3,4-c]-pyridin-7-ones as factor Xa inhibitors
US6750225B2 (en) 2001-04-18 2004-06-15 Bristol-Myers Squibb Pharms Company 1,4,5,6-tetrahydropyrazolo-[3,4,-c]-pyridin-7-ones useful as factor Xa inhibitors
EP1414449A4 (en) * 2001-05-22 2005-04-06 Bristol Myers Squibb Co FACTOR XA BICYCLIC INHIBITORS
TWI320039B (en) 2001-09-21 2010-02-01 Lactam-containing compounds and derivatives thereof as factor xa inhibitors
MXPA04002526A (es) 2001-09-21 2004-05-31 Bristol Myers Squibb Co Compuestos que contienen lactama y sus derivados como inhibidores del factor xa.
TW200302225A (en) 2001-12-04 2003-08-01 Bristol Myers Squibb Co Substituted amino methyl factor Xa inhibitors
WO2003048081A2 (en) * 2001-12-04 2003-06-12 Bristol-Myers Squibb Company Glycinamides as factor xa inhibitors
TW200738672A (en) * 2001-12-10 2007-10-16 Bristol Myers Squibb Co Intermediated for the preparation of 4,5-dihydro-pyrazolo [3,4-c] pyrid-2-ones
PL206962B1 (pl) * 2001-12-19 2010-10-29 Bristol Myers Squibb Co Związek heterocykliczny o budowie skondensowanej
ES2373875T3 (es) * 2002-03-05 2012-02-09 Transtech Pharma, Inc. Derivados de azol mono y bicíclicos que inhiben la interacción de ligandos con rage.
US7312214B2 (en) 2002-05-10 2007-12-25 Bristol-Myers Squibb Company 1, 1-disubstituted cycloalkyl derivatives as factor Xa inhibitors
PT1569912E (pt) 2002-12-03 2015-09-15 Pharmacyclics Llc Derivados 2-(2-hidroxibifenil-3-il)-1h-benzoimidazole-5- carboxamidina como inibidores do fator viia
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CN103992310B (zh) * 2013-05-14 2016-07-06 中国医学科学院医药生物技术研究所 一组取代苯并杂环胺衍生物及其制备方法和作为impdh抑制剂的相关应用
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CN105085515B (zh) * 2014-05-22 2019-02-01 华北制药股份有限公司 作为凝血因子Xa抑制剂的酰肼类化合物
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CN104277039B (zh) * 2014-09-19 2016-06-01 广东东阳光药业有限公司 含有取代丁炔基的吡唑并哌啶酮类化合物及其组合物及用途
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Also Published As

Publication number Publication date
PT1140941E (pt) 2005-02-28
DE69921358D1 (de) 2004-11-25
WO2000039131A1 (en) 2000-07-06
NO20013072D0 (no) 2001-06-20
EP1140941A1 (en) 2001-10-10
CN100340559C (zh) 2007-10-03
TWI225862B (en) 2005-01-01
CN1391575A (zh) 2003-01-15
HK1052508A1 (en) 2003-09-19
DE69921358T2 (de) 2006-03-09
CA2349330C (en) 2009-09-29
ES2232202T3 (es) 2005-05-16
AU2371700A (en) 2000-07-31
NZ511674A (en) 2003-11-28
ZA200103795B (en) 2002-08-12
US20030004167A1 (en) 2003-01-02
IL142959A0 (en) 2002-04-21
BR9917080A (pt) 2002-03-12
AR024242A1 (es) 2002-09-25
CA2349330A1 (en) 2000-07-06
SI1140941T1 (en) 2005-04-30
KR20010092754A (ko) 2001-10-26
HRP990396A2 (en) 2000-08-31
HK1052508B (zh) 2008-08-01
MXPA01006502A (es) 2002-04-08
MY138239A (en) 2009-05-29
JP2002533465A (ja) 2002-10-08
IL142959A (en) 2010-05-31
US6413980B1 (en) 2002-07-02
KR100628407B1 (ko) 2006-09-26
DK1140941T3 (da) 2005-02-14
NO319816B1 (no) 2005-09-19
EA004515B1 (ru) 2004-04-29
ATE280171T1 (de) 2004-11-15
AU759711B2 (en) 2003-04-17
EA200100688A1 (ru) 2001-12-24
EP1140941B1 (en) 2004-10-20
US6673810B2 (en) 2004-01-06

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