NO20003261L - Mixtures derived from Mycobacterium vaccae and methods for their use - Google Patents
Mixtures derived from Mycobacterium vaccae and methods for their useInfo
- Publication number
- NO20003261L NO20003261L NO20003261A NO20003261A NO20003261L NO 20003261 L NO20003261 L NO 20003261L NO 20003261 A NO20003261 A NO 20003261A NO 20003261 A NO20003261 A NO 20003261A NO 20003261 L NO20003261 L NO 20003261L
- Authority
- NO
- Norway
- Prior art keywords
- vaccae
- methods
- delipidated
- mycobacterium vaccae
- mixtures derived
- Prior art date
Links
- 241000187644 Mycobacterium vaccae Species 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 2
- 150000007513 acids Chemical class 0.000 abstract 2
- SATHPVQTSSUFFW-UHFFFAOYSA-N 4-[6-[(3,5-dihydroxy-4-methoxyoxan-2-yl)oxymethyl]-3,5-dihydroxy-4-methoxyoxan-2-yl]oxy-2-(hydroxymethyl)-6-methyloxane-3,5-diol Chemical compound OC1C(OC)C(O)COC1OCC1C(O)C(OC)C(O)C(OC2C(C(CO)OC(C)C2O)O)O1 SATHPVQTSSUFFW-UHFFFAOYSA-N 0.000 abstract 1
- 229920000189 Arabinogalactan Polymers 0.000 abstract 1
- 239000001904 Arabinogalactan Substances 0.000 abstract 1
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 235000019312 arabinogalactan Nutrition 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 239000000706 filtrate Substances 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 208000026278 immune system disease Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Mycology (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
Det beskrives blandinger som forekommer i, eller kan avledes fra, Mycobactehum vaccae, samt fremgangsmåter for deres anvendelse ved behandling, forebyggelse og påvisning av forstyrrelser inklusivt infeksjonssykdommer, immunforstyrrelser og cancer. Fremgangsmåter for forbedring av immunresponsen mot et antigen og som innbefatter administrering av M. vaccae-kulturfiltrat, delipiderte M. vaccae-celler, delipiderte og deglykolipiderte M. vaccae-celler utarmet med hensyn til mykolsyrer, og delipiderte og deglykolipiderte M. vaccae-celler utarmet med hensyn til mykolsyrer og arabinogalaktan, er også beskrevet.It describes compounds that occur in, or can be derived from, Mycobactehum vaccae, as well as methods for their use in the treatment, prevention and detection of disorders including infectious diseases, immune disorders and cancer. Methods of enhancing the immune response to an antigen comprising administering M. vaccae culture filtrate, delipidated M. vaccae cells, delipidated and deglycolipidated M. vaccae cells depleted of mycolic acids, and delipidated and deglycolipidated M. vaccae cells depleted with respect to mycolic acids and arabinogalactan, is also described.
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US99662497A | 1997-12-23 | 1997-12-23 | |
US08/997,362 US5985287A (en) | 1996-08-29 | 1997-12-23 | Compounds and methods for treatment and diagnosis of mycobacterial infections |
US08/997,080 US5968524A (en) | 1997-12-23 | 1997-12-23 | Methods and compounds for the treatment of immunologically-mediated psoriasis |
US09/095,855 US6160093A (en) | 1996-08-29 | 1998-06-11 | Compounds and methods for treatment and diagnosis of mycobacterial infections |
US15618198A | 1998-09-17 | 1998-09-17 | |
US09/205,426 US6406704B1 (en) | 1996-08-29 | 1998-12-04 | Compounds and methods for treatment and diagnosis of mycobacterial infections |
PCT/NZ1998/000189 WO1999032634A2 (en) | 1997-12-23 | 1998-12-23 | Compositions derived from mycobacterium vaccae and methods for their use |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20003261D0 NO20003261D0 (en) | 2000-06-22 |
NO20003261L true NO20003261L (en) | 2000-08-22 |
Family
ID=27557521
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20003261A NO20003261L (en) | 1997-12-23 | 2000-06-22 | Mixtures derived from Mycobacterium vaccae and methods for their use |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP1044273A2 (en) |
JP (1) | JP2002514385A (en) |
CN (1) | CN1294632A (en) |
AU (1) | AU746311B2 (en) |
BR (1) | BR9814432A (en) |
CA (1) | CA2315539A1 (en) |
HU (1) | HUP0100352A2 (en) |
ID (1) | ID26327A (en) |
IL (1) | IL136821A0 (en) |
MX (1) | MXPA00006168A (en) |
NO (1) | NO20003261L (en) |
NZ (1) | NZ505834A (en) |
PL (1) | PL341697A1 (en) |
TR (1) | TR200001948T2 (en) |
WO (1) | WO1999032634A2 (en) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6569436B1 (en) | 1998-10-05 | 2003-05-27 | The Malaghan Institute Of Medical Research | Method of using a vaccine |
JP4415200B2 (en) * | 1999-01-29 | 2010-02-17 | 大塚製薬株式会社 | Late-growing mycobacterial polypeptide |
GB9903539D0 (en) | 1999-02-16 | 1999-04-07 | Stanford Rook Ltd | Therapy using M.Vaccae |
US6350457B1 (en) * | 1999-06-02 | 2002-02-26 | Genesis Research & Development Corporation Limited | Methods and compounds for the treatment of immunologically-mediated diseases using mycobacterium vaccae |
JP2003504079A (en) * | 1999-07-12 | 2003-02-04 | ジェネシス リサーチ アンド デベロップメント コーポレイション リミテッド | Compositions for treating infectious diseases and immune system diseases and methods of using the same |
US7217554B2 (en) | 1999-08-31 | 2007-05-15 | Novozymes A/S | Proteases and variants thereof |
JP2003508054A (en) * | 1999-08-31 | 2003-03-04 | ニーデルバイス,ミヒャエル | Method for producing channel-forming protein |
EP2336331A1 (en) * | 1999-08-31 | 2011-06-22 | Novozymes A/S | Novel proteases and variants thereof |
US6361776B1 (en) * | 1999-12-06 | 2002-03-26 | Genesis Research & Development Corp. Ltd. | Compounds isolated from M. vaccae and their use in modulation of immune responses |
EP1254953A4 (en) * | 1999-12-28 | 2004-06-02 | Toyoshima Kumao | Maturation-promoting agent for immature dendritic cells |
AUPQ761200A0 (en) | 2000-05-19 | 2000-06-15 | Hunter Immunology Limited | Compositions and methods for treatment of mucosal infections |
US20030104012A1 (en) * | 2001-05-11 | 2003-06-05 | Corixa Corporation | Vaccines for the treatment of autoimmune disease |
US20030147861A1 (en) * | 2001-07-26 | 2003-08-07 | Genesis Research And Development Corporation Limited | Compounds and methods for the modulation of immune responses |
AU2002353366A1 (en) * | 2001-12-10 | 2003-06-23 | Bakulesh Mafatlal Khamar | The process of manufacturing a pharmaceutical composition useful for management of cancer |
GB0303507D0 (en) * | 2003-02-14 | 2003-03-19 | Novartis Ag | Organic compounds |
CN106103471B (en) * | 2014-01-09 | 2020-01-07 | 特兰斯吉恩股份有限公司 | Fusion of heterooligomeric mycobacterial antigens |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8919321D0 (en) * | 1989-08-25 | 1989-10-11 | Univ London | Treatment of chronic inflammatory conditions |
GB9203814D0 (en) * | 1992-02-21 | 1992-04-08 | Univ London | Treatment of long term auto-immune conditions |
US6284255B1 (en) * | 1996-08-29 | 2001-09-04 | Genesis Research & Development Corporation Limited | Compounds and methods for treatment and diagnosis of mycobacterial infections |
-
1998
- 1998-12-23 IL IL13682198A patent/IL136821A0/en unknown
- 1998-12-23 MX MXPA00006168A patent/MXPA00006168A/en unknown
- 1998-12-23 BR BR9814432-4A patent/BR9814432A/en not_active IP Right Cessation
- 1998-12-23 EP EP98963665A patent/EP1044273A2/en not_active Withdrawn
- 1998-12-23 PL PL98341697A patent/PL341697A1/en unknown
- 1998-12-23 HU HU0100352A patent/HUP0100352A2/en unknown
- 1998-12-23 CA CA002315539A patent/CA2315539A1/en not_active Abandoned
- 1998-12-23 WO PCT/NZ1998/000189 patent/WO1999032634A2/en not_active Application Discontinuation
- 1998-12-23 TR TR2000/01948T patent/TR200001948T2/en unknown
- 1998-12-23 JP JP2000525553A patent/JP2002514385A/en active Pending
- 1998-12-23 NZ NZ505834A patent/NZ505834A/en unknown
- 1998-12-23 AU AU18936/99A patent/AU746311B2/en not_active Ceased
- 1998-12-23 CN CN98813781A patent/CN1294632A/en active Pending
- 1998-12-23 ID IDW20001433A patent/ID26327A/en unknown
-
2000
- 2000-06-22 NO NO20003261A patent/NO20003261L/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO1999032634A3 (en) | 1999-12-02 |
NO20003261D0 (en) | 2000-06-22 |
ID26327A (en) | 2000-12-14 |
HUP0100352A2 (en) | 2001-06-28 |
IL136821A0 (en) | 2001-06-14 |
CA2315539A1 (en) | 1999-07-01 |
MXPA00006168A (en) | 2005-02-24 |
WO1999032634A2 (en) | 1999-07-01 |
JP2002514385A (en) | 2002-05-21 |
EP1044273A2 (en) | 2000-10-18 |
NZ505834A (en) | 2002-12-20 |
CN1294632A (en) | 2001-05-09 |
BR9814432A (en) | 2000-10-10 |
PL341697A1 (en) | 2001-04-23 |
TR200001948T2 (en) | 2001-02-21 |
AU746311B2 (en) | 2002-04-18 |
AU1893699A (en) | 1999-07-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |