NO173873C - Analogifremgangsmaate til fremstilling av en terapeutisk aktiv monosakkaridforbindelse - Google Patents

Analogifremgangsmaate til fremstilling av en terapeutisk aktiv monosakkaridforbindelse

Info

Publication number: NO173873C
Authority: NO; Norway
Prior art keywords: preparation; therapeutically active; analogous procedure; monosaccharide compound; active monosaccharide
Prior art date: 1989-01-09

Application number

NO895067A

Other languages

English (en)

Other versions

NO895067D0 (no

NO895067L (no

NO173873B (no

Inventor

Bruce Rosen

Sudershan K Arora

Albert Varghese Thomas

Original Assignee

Greenwich Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-01-09

Filing date

1989-12-15

Publication date

1994-02-16

1989-12-15 Application filed by Greenwich Pharma filed Critical Greenwich Pharma

1989-12-15 Publication of NO895067D0 publication Critical patent/NO895067D0/no

1990-07-10 Publication of NO895067L publication Critical patent/NO895067L/no

1993-01-19 Priority to NO930171A priority Critical patent/NO174554C/no

1993-11-08 Publication of NO173873B publication Critical patent/NO173873B/no

1994-02-16 Publication of NO173873C publication Critical patent/NO173873C/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/08—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to sulfur, selenium or tellurium
- C07H5/10—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to sulfur, selenium or tellurium to sulfur
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
- C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
- C07H9/04—Cyclic acetals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Crystallography & Structural Chemistry (AREA)
Immunology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Rheumatology (AREA)
Transplantation (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Saccharide Compounds (AREA)

NO895067A 1989-01-09 1989-12-15 Analogifremgangsmaate til fremstilling av en terapeutisk aktiv monosakkaridforbindelse NO173873C (no)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
NO930171A NO174554C (no)	1989-01-09	1993-01-19	Fremgangsmåte til fremstilling av 1,2:3,5-di-O-iso-propyliden-

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/294,838 US4996195A (en)	1989-01-09	1989-01-09	Derivatives of α,D-glucofuranose or α,D-allofuranose and intermediates for preparing these derivatives

Publications (4)

Publication Number	Publication Date
NO895067D0 NO895067D0 (no)	1989-12-15
NO895067L NO895067L (no)	1990-07-10
NO173873B NO173873B (no)	1993-11-08
NO173873C true NO173873C (no)	1994-02-16

Family

ID=23135159

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO895067A NO173873C (no)	1989-01-09	1989-12-15	Analogifremgangsmaate til fremstilling av en terapeutisk aktiv monosakkaridforbindelse

Country Status (9)

Country	Link
US (1)	US4996195A (no)
EP (1)	EP0379397A3 (no)
JP (1)	JPH02262586A (no)
KR (1)	KR900011784A (no)
AU (1)	AU616335B2 (no)
CA (1)	CA2007308A1 (no)
IL (1)	IL92425A0 (no)
NO (1)	NO173873C (no)
ZA (1)	ZA899026B (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5298494A (en) *	1989-01-09	1994-03-29	Greenwich Pharmaceuticals Incorporated	Monosaccharides having anti-proliferation and anti-inflammatory activity, compositions and uses thereof
US5010058A (en) *	1989-06-22	1991-04-23	501 Greenwich Pharmaceuticals Incorporated	3,5,6-substituted derivatives of 1,2-O-isopropylidene-α,D-glucofuranose and intermediates for preparing these derivatives
WO1992004359A2 (en) *	1990-09-12	1992-03-19	Greenwich Pharmaceuticals, Inc.	Monosaccharides having anti-proliferation and anti-inflammatory activity, compositions and uses thereof
IL100833A0 (en) *	1991-02-20	1992-09-06	Greenwich Pharma	Method for synthesis of ethereally substituted blocked monosaccharides
GB9125002D0 (en) *	1991-11-25	1992-01-22	Ici Plc	Azole derivatives
US5360792A (en) *	1991-12-20	1994-11-01	Greenwich Pharmaceuticals Incorporated	Anti-proliferative and anti-inflammatory compounds: 5- or 6-deoxy hexose monosaccharides having a saturated nitrogen-containing heterocycle at the 5- or 6-position bound through the nitrogen atom
FR2694753B1 (fr) *	1992-07-09	1994-12-23	Picardie Jules Verne Universit	Procédés de synthèse spécifique de nouveaux aminothioéthers par substitution des sites hydroxylés sur des molécules mono ou polyhydroxylées, produits obtenus par ces procédés et leurs applications.
US5360794A (en) *	1992-08-03	1994-11-01	Medicarb Inc.	Disubstituted and deoxy disubstituted derivatives of α-D-mannofuranosides and β-L-gulofuranosides having anti-inflammatory and anti-proliferative activity
US5367062A (en) *	1992-08-21	1994-11-22	Medicarb Inc.	Disubstituted and deoxydisubstituted derivatives of α-d-lyxofuranosides having anti-inflammatory and anti-proliferative activity
US5432163A (en) *	1992-11-13	1995-07-11	Greenwich Pharmaceuticals Incorporated	Anti-proliferative and anti-inflammatory compounds: derivatives of pentose monosaccharides
JPH09501148A (ja) *	1993-06-11	1997-02-04	ボストンライフサイエンシィズ，インコーポレイテッド	免疫調節性、抗炎症性および抗増殖性化合物：イドースの５，６−ジデオキシ，５−アミノ誘導体およびグルコースの６−デオキシ，６−アミノ誘導体
US6329344B1 (en)	1998-10-22	2001-12-11	Ranbaxy Laboratories Limited	Derivatives of monosaccharides as cell adhesion inhibitors
IN190975B (no)	1999-01-15	2003-09-06	Ranbaxy Lab Ltd
DE60203008T2 (de) *	2001-06-07	2006-03-02	Santaris Pharma A/S	Verbesserte synthesen von allofuranose
WO2006024926A1 (en) *	2004-09-02	2006-03-09	Ranbaxy Laboratories Limited	Monosaccharide derivatives
EP1902063A2 (en) *	2004-12-22	2008-03-26	Ranbaxy Laboratories Limited	Derivatives of pentose monosaccharides as anti-inflammatory compounds
EP1842855A3 (en) *	2006-03-29	2007-12-05	Ranbaxy Laboratories Limited	Monosaccharide derivatives as anti-inflammatory and/or anti-cancer agents
US7790689B2 (en) *	2006-05-30	2010-09-07	Ranbaxy Laboratories Limited	Monosaccharide derivatives
US20080300196A1 (en) *	2006-10-03	2008-12-04	Ashwani Kumar Verma	Monosaccharide derivatives

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2461478A (en) *	1946-12-18	1949-02-08	Gen Aniline & Film Corp	Gelatin subbing compositions having antistatic properties
US2875194A (en) *	1955-10-05	1959-02-24	American Cyanamid Co	Derivatives of 5-amino-d-ribofuranose
US2960452A (en) *	1958-07-14	1960-11-15	Miles Lab	Preparation of diacetone 2-keto-gulonic acid
US3586664A (en) *	1969-03-19	1971-06-22	Eisai Co Ltd	Xylose derivatives and preparation thereof
US3832355A (en) *	1970-05-13	1974-08-27	Hoffmann La Roche	Catalytic oxidation process
US4032650A (en) *	1972-09-15	1977-06-28	A.E.C. Societe De Chimie Organique Et Biologique	Method of treating fatigue by administering a gulonic acid salt
USRE32268E (en) *	1973-03-01	1986-10-21	Strategic Medical Research Corp.	Therapeutic composition and method of therapeutically treating warm blooded animals therewith
US3939145A (en) *	1973-03-01	1976-02-17	Strategic Medical Research Corporation	Novel ethereally monosubstituted monosaccharides
USRE30379E (en) *	1973-03-01	1980-08-19	Strategic Medical Research Corp.	Ethereal monosubstitutions of monosaccharide derivatives
US3939146A (en) *	1973-03-01	1976-02-17	Strategic Medical Research Corporation	Novel ethereal monosubstitutions of monosaccharide derivatives
US4016261A (en) *	1973-03-01	1977-04-05	Strategic Medical Research Corporation	Therapeutic composition and method of therapeutically treating warm blooded animals therewith
US3965262A (en) *	1973-03-01	1976-06-22	Strategic Medical Research Corporation	Method of enhancing learning and/or memory in warm blooded animals
US4017608A (en) *	1973-12-14	1977-04-12	Strategic Medical Research Corporation	Therapeutic composition and method of therapeutically treating warm blooded animals therewith
US4056322A (en) *	1973-12-14	1977-11-01	Strategic Medical Research Corporation	Preparation of ethers of monosaccharides
IN141230B (no) *	1973-12-14	1977-02-05	Strategic Medical Res Corp
US4010275A (en) *	1975-03-18	1977-03-01	Ciba-Geigy Corporation	Treatment of osteoarthritis
GB1589916A (en) *	1976-11-16	1981-05-20	Prodotti Antibiotici Spa	Glucofuranose derivatives
USRE30354E (en) *	1978-02-17	1980-07-29	Strategic Medical Research Corp.	Novel ethereally monosubstituted monosaccharides
DE2830469A1 (de) *	1978-07-11	1980-01-24	Bayer Ag	Herstellung von l-desoxy-nojirimycin und n-substituierten derivaten
US4735934A (en) *	1981-02-17	1988-04-05	Greenwich Pharmaceuticals Incorporated	Method of therapeutically treating a warm blooded animal afflicted with an autoimmune disease
US4738953A (en) *	1981-02-17	1988-04-19	Greenwich Pharmaceuticals Incorporated	Method of therapeutically treating a warm blooded animal afflicted with an autoimmune disease and a synergistic composition therefor
US4554349A (en) *	1983-10-11	1985-11-19	Merck & Co., Inc.	Aralkyl and aralkenyl glycosides as inhibitors of antigen-specific T-cell proliferation
JPS6222703A (ja) *	1985-07-22	1987-01-30	Ss Pharmaceut Co Ltd	植物生長調節剤

1989
- 1989-01-09 US US07/294,838 patent/US4996195A/en not_active Expired - Fee Related
- 1989-11-23 IL IL92425A patent/IL92425A0/xx unknown
- 1989-11-27 ZA ZA899026A patent/ZA899026B/xx unknown
- 1989-11-29 JP JP1307827A patent/JPH02262586A/ja active Pending
- 1989-12-15 NO NO895067A patent/NO173873C/no unknown
1990
- 1990-01-04 AU AU47648/90A patent/AU616335B2/en not_active Ceased
- 1990-01-08 CA CA002007308A patent/CA2007308A1/en not_active Abandoned
- 1990-01-09 EP EP19900400066 patent/EP0379397A3/en not_active Withdrawn
- 1990-01-09 KR KR1019900000197A patent/KR900011784A/ko not_active Application Discontinuation

Also Published As

Publication number	Publication date
CA2007308A1 (en)	1990-07-09
EP0379397A2 (en)	1990-07-25
AU616335B2 (en)	1991-10-24
ZA899026B (en)	1990-12-28
NO895067D0 (no)	1989-12-15
AU4764890A (en)	1990-08-09
NO895067L (no)	1990-07-10
NO173873B (no)	1993-11-08
IL92425A0 (en)	1990-07-26
JPH02262586A (ja)	1990-10-25
US4996195A (en)	1991-02-26
KR900011784A (ko)	1990-08-02
EP0379397A3 (en)	1992-11-04

Publication	Publication Date	Title
NO179584C (no)	1996-11-06	Analogifremgangsmåte for fremstilling av terapeutisk aktive 2-acylaminotiazoler
FI96861C (fi)	1996-09-10	Menetelmä terapeuttisesti aktiivisten substituoitujen indolyylipyrrolijohdannaisten valmistamiseksi
NO173873C (no)	1994-02-16	Analogifremgangsmaate til fremstilling av en terapeutisk aktiv monosakkaridforbindelse
NO175978C (no)	1995-01-11	Analogifremgangsmåte for fremstilling av terapeutisk aktive bis-aza-bicykliske forbindelser
NO872946D0 (no)	1987-07-15	Analogifremgangsmaate for fremstilling av terapeutisk aktive benzensulfonamidoindanylforbindelser.
NO894842D0 (no)	1989-12-04	Analogifremgangsmaate for fremstilling av terapeutisk virksomme imidazoler.
NO179448C (no)	1996-10-09	Analogifremgangsmåte for fremstilling av terapeutisk aktive forbindelser
NO162113C (no)	1989-11-08	Analogifremgangsmaate for fremstilling av terapeutisk aktive fenetanolaminforbindelser.
NO900032L (no)	1990-07-06	Fremgangsmaate for fremstilling av terapeutisk aktive tiazol-forbindelser.
NO165397C (no)	1991-02-06	Analogifremgangsmaate for fremstilling av terapeutisk aktive tiazolforbindelser.
NO903941D0 (no)	1990-09-10	Analogifremgangsmaate for fremstilling av terapeutisk aktive diazepinon-derivater.
NO895199L (no)	1990-08-17	Analogifremgangsmaate for fremstilling av terapeutisk virksomme kinolinsystemforbindelser.
NO173334C (no)	1993-12-01	Analogifremgangsm}te for fremstilling av terapeutisk aktive alkylaminoalkylenderivater 2H-1-benzopyraner
NO169963C (no)	1992-08-26	Analogifremgangsmaate til fremstilling av terapeutisk aktive, substituerte 3,4-dihydro-2h-benzopyraner
NO173784C (no)	1994-02-02	Anaslogifremgangsmaate for fremstilling av terapeutisk aktive tieno-tri-azolo-diazepinderivater
NO173239C (no)	1993-11-17	Analogifremgangsmaate til fremstilling av et terapeutisk aktivt etopodofyllotoksinglukosidacylderivat
NO173503C (no)	1993-12-22	Analogifremgangsmaate for fremstilling av terapeutisk aktive tetrahydroimidayo (1,4) benzodiazepin-2-tioner
NO173335C (no)	1993-12-01	Analogifremgangsm}te til fremstilling av en terapeutisk aktiv epipodofyllotoksinaltrosidforbindelse
NO174203C (no)	1994-04-06	Analogifremgangsmåte for fremstilling av terapeutisk aktive
NO174200C (no)	1994-04-06	Analogifremgangsmåte for fremstilling av terapeutisk aktive 2-imino-6-polyfluoralkoksybenzotiazol-forbindelser
NO894949L (no)	1990-06-11	Analogifremgangsmaate for fremstilling av terapeutisk virksomme benzopyranylpyrrolinonderivater.
NO173606C (no)	1994-01-05	Analogifremgangsmaate for fremstilling av terapeutisk aktive tieno- triazolo-diazepin-derivater
NO304428B1 (no)	1998-12-14	AnalogifremgangsmÕte for fremstilling av terapeutisk aktive vinylazoler
NO168530C (no)	1992-03-04	Analogifremgangsmaate for fremstilling av terapeutisk aktive benzoksazoninforbindelser.
NO175476C (no)	1994-10-19	Analogifremgangsmåte ved fremstilling av terapeutisk aktive cykloalkyltiazolderinvater