NL191709C - C8-gesubstitueerde ergolinederivaten alsmede geneesmiddel dat deze derivaten omvat. - Google Patents

C8-gesubstitueerde ergolinederivaten alsmede geneesmiddel dat deze derivaten omvat.

Info

Publication number: NL191709C
Authority: NL; Netherlands
Prior art keywords: derivatives; drug; well; substituted ergoline; substituted
Prior art date: 1982-04-30

Application number

NL8301529A

Other languages

English (en)

Dutch (nl)

Other versions

NL191709B (nl

NL8301529A (nl

Original Assignee

Erba Farmitalia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-04-30

Filing date

1983-04-29

Publication date

1996-04-02

1983-04-29 Application filed by Erba Farmitalia filed Critical Erba Farmitalia

1983-11-16 Publication of NL8301529A publication Critical patent/NL8301529A/nl

1995-12-01 Publication of NL191709B publication Critical patent/NL191709B/xx

1996-04-02 Application granted granted Critical

1996-04-02 Publication of NL191709C publication Critical patent/NL191709C/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NL8301529A 1982-04-30 1983-04-29 C8-gesubstitueerde ergolinederivaten alsmede geneesmiddel dat deze derivaten omvat. NL191709C (nl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB8212653		1982-04-30
GB8212653		1982-04-30

Publications (3)

Publication Number	Publication Date
NL8301529A NL8301529A (nl)	1983-11-16
NL191709B NL191709B (nl)	1995-12-01
NL191709C true NL191709C (nl)	1996-04-02

Family

ID=10530108

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NL8301529A NL191709C (nl)	1982-04-30	1983-04-29	C8-gesubstitueerde ergolinederivaten alsmede geneesmiddel dat deze derivaten omvat.

Country Status (21)

Country	Link
US (1)	US4657914A (xx)
JP (1)	JPS58194884A (xx)
AT (1)	AT385035B (xx)
AU (1)	AU553851B2 (xx)
BE (1)	BE896609A (xx)
CA (1)	CA1210389A (xx)
CH (1)	CH654305A5 (xx)
CS (1)	CS236874B2 (xx)
DE (1)	DE3314878A1 (xx)
DK (1)	DK164058C (xx)
FI (1)	FI73996C (xx)
FR (1)	FR2526022B1 (xx)
GB (1)	GB2120242A (xx)
GR (1)	GR78842B (xx)
HU (1)	HU193527B (xx)
IE (1)	IE53950B1 (xx)
IL (1)	IL68496A (xx)
IT (1)	IT1215630B (xx)
NL (1)	NL191709C (xx)
SE (1)	SE460967B (xx)
ZA (1)	ZA833008B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8714767D0 (en) *	1987-06-24	1987-07-29	Erba Farmitalia	Egoline derivatives
HU190105B (en) *	1983-06-03	1986-08-28	Gyogyszerkutato Intezet	Process for production of pirazolyl-methyl-ergolin- derivatives and their acid additional salts
GB2173189B (en) *	1985-02-21	1988-04-27	Maruko Pharmaceutical Co	Ergoline derivatives and salts thereof and pharmaceutical compositions thereof
GB8702364D0 (en) *	1987-02-03	1987-03-11	Erba Farmitalia	Ergolinyl heterocycles
US8877795B2 (en)	2010-05-07	2014-11-04	The Board Of Trustees Of The Leland Stanford Junior University	Identification of stabilizers of multimeric proteins
JP6543342B2 (ja)	2014-08-14	2019-07-10	アルハマドシャー，マモウン，エム．	血清半減期を延長するための、調節可能リンカーを介した薬学的活性剤とトランスサイレチンリガンドのコンジュゲーション
EA201991921A1 (ru)	2017-02-17	2020-02-06	Эйдос Терапьютикс, Инк.	Способы получения ag-10, его промежуточных соединений и их солей
MA52137A (fr)	2018-03-23	2021-01-27	Eidos Therapeutics Inc	Méthodes de traitement de l'amylose ttr à l'aide d'ag10
UA128256C2 (uk)	2018-08-17	2024-05-22	Ейдос Терапьютікс, Інк.	Препарати ag10

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3238211A (en) *		1966-03-01		Derhvatives of g-methyl and i,g-dimethyl ergolhne
US3296071A (en) *	1963-05-31	1967-01-03	Upjohn Co	Reducing blood sugar with 3-alkyl-5-alkoxymethylisoxazole
CH507248A (de) *	1967-03-16	1971-05-15	Spofa Vereinigte Pharma Werke	Verfahren zur Herstellung von D-6-Methylergolin(I)ylessigsäure
US3957785A (en) *	1971-12-02	1976-05-18	Societa' Farmaceutici Italia S.P.A.	Bβ-Pyrimidino-aminomethyl-10α-ergoline and 10α-methoxyergoline derivatives
CH563376A5 (xx) *	1972-06-29	1975-06-30	Lonza Ag
US3996228A (en) *	1973-12-21	1976-12-07	Societa' Farmaceutici Italia S.P.A.	Pyrimidinoaminoethyl ergoline derivatives
NL7416120A (nl) *	1973-12-21	1975-06-24	Farmaceutici Italia	Werkwijze voor het bereiden van pyrimidinoami- nomethylergolinederivaten.
US4147789A (en) *	1974-03-14	1979-04-03	Sandoz Ltd.	6-Methyl-8-thiomethyl-ergolene derivatives
IE41533B1 (en) *	1974-03-14	1980-01-30	Sandoz Ltd	Thiomethyl ergolene derivatives
CS171480B1 (xx) *	1974-03-19	1976-10-29
CS177530B1 (en) *	1974-07-19	1977-07-29	Miroslav Semonsky	New nbeta-substituted derivatives of b-beta-aminoethyl-ergoline-i their salts and methods for the production thereof
CH617452A5 (xx) *	1974-10-25	1980-05-30	Hoffmann La Roche
CH615929A5 (en) *	1975-06-02	1980-02-29	Sandoz Ag	Process for the preparation of novel ergoline compounds
CH622518A5 (en) *	1976-12-14	1981-04-15	Sandoz Ag	Process for the preparation of novel ergoline compounds
AU526764B2 (en) *	1978-09-08	1983-01-27	Farmitalia Carlo Erba S.P.A.	Ergoline derivatives
GB2056437A (en) *	1979-08-07	1981-03-18	Erba Farmitalia	Secoergoline derivatives
US4382940A (en) *	1979-12-06	1983-05-10	Farmitalia Carlo Erba S.P.A.	Ercoline derivatives and therapeutic compositions having CNS affecting activity

1983
- 1983-04-21 GB GB08310843A patent/GB2120242A/en not_active Withdrawn
- 1983-04-25 US US06/488,168 patent/US4657914A/en not_active Expired - Fee Related
- 1983-04-25 FI FI831406A patent/FI73996C/fi not_active IP Right Cessation
- 1983-04-25 GR GR71190A patent/GR78842B/el unknown
- 1983-04-25 CS CS832921A patent/CS236874B2/cs unknown
- 1983-04-25 IE IE932/83A patent/IE53950B1/en not_active IP Right Cessation
- 1983-04-25 DE DE19833314878 patent/DE3314878A1/de active Granted
- 1983-04-26 IL IL68496A patent/IL68496A/xx not_active IP Right Cessation
- 1983-04-26 JP JP58072295A patent/JPS58194884A/ja active Granted
- 1983-04-26 CH CH2256/83A patent/CH654305A5/it not_active IP Right Cessation
- 1983-04-27 SE SE8302379A patent/SE460967B/sv not_active IP Right Cessation
- 1983-04-27 CA CA000426874A patent/CA1210389A/en not_active Expired
- 1983-04-27 IT IT8320807A patent/IT1215630B/it active
- 1983-04-27 FR FR8306926A patent/FR2526022B1/fr not_active Expired
- 1983-04-27 HU HU851631A patent/HU193527B/hu not_active IP Right Cessation
- 1983-04-28 AU AU14029/83A patent/AU553851B2/en not_active Ceased
- 1983-04-28 ZA ZA833008A patent/ZA833008B/xx unknown
- 1983-04-28 DK DK189983A patent/DK164058C/da not_active IP Right Cessation
- 1983-04-29 NL NL8301529A patent/NL191709C/xx not_active IP Right Cessation
- 1983-04-29 BE BE0/210660A patent/BE896609A/fr not_active IP Right Cessation
- 1983-04-29 AT AT0156783A patent/AT385035B/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
SE8302379D0 (sv)	1983-04-27
CS236874B2 (en)	1985-05-15
AU553851B2 (en)	1986-07-31
NL191709B (nl)	1995-12-01
DE3314878A1 (de)	1983-11-03
DK164058B (da)	1992-05-04
FR2526022A1 (fr)	1983-11-04
NL8301529A (nl)	1983-11-16
JPS58194884A (ja)	1983-11-12
IL68496A0 (en)	1983-07-31
FI831406A0 (fi)	1983-04-25
CH654305A5 (it)	1986-02-14
ATA156783A (de)	1987-07-15
FI73996B (fi)	1987-08-31
GR78842B (xx)	1984-10-02
FI831406L (fi)	1983-10-31
IT8320807A0 (it)	1983-04-27
CA1210389A (en)	1986-08-26
SE8302379L (sv)	1983-10-31
DK189983D0 (da)	1983-04-28
SE460967B (sv)	1989-12-11
DK189983A (da)	1983-10-31
IE53950B1 (en)	1989-04-26
FR2526022B1 (fr)	1985-06-14
US4657914A (en)	1987-04-14
BE896609A (fr)	1983-08-16
GB2120242A (en)	1983-11-30
AT385035B (de)	1988-02-10
AU1402983A (en)	1983-11-03
IL68496A (en)	1985-06-30
IE830932L (en)	1983-10-30
HU193527B (en)	1987-10-28
GB8310843D0 (en)	1983-05-25
ZA833008B (en)	1984-01-25
DE3314878C2 (xx)	1993-09-23
DK164058C (da)	1992-10-12
JPH0354668B2 (xx)	1991-08-20
IT1215630B (it)	1990-02-22
FI73996C (fi)	1987-12-10

Publication	Publication Date	Title
NO851921L (no)	1985-11-18	Fremgangsmaate for fremstilling av pyrido-imidazo-rifanycin-derivater.
NO821886L (no)	1982-12-07	Bis-triazolderivat.
NL191540C (nl)	1995-09-04	Verbinding met antihypercholesteremische werkzaamheid, alsmede farmaceutisch preparaat dat deze verbinding bevat.
NO851466L (no)	1985-10-14	Fremgangsmaate for fremstilling av 9a-aza-9a-homoery-tromycin-derivater.
NO865201D0 (no)	1986-12-19	Fremgangsmaate for plassering av et fralands plattformtaarn.
NO881182D0 (no)	1988-03-17	Innretning for aa lage sigaretter.
ATE34383T1 (de)	1988-06-15	Oxamidsaeure-derivate.
DE3581891D1 (de)	1991-04-04	Cephalosporinderivate.
NO885166D0 (no)	1988-11-18	Ergolinderivater.
DE3872153D1 (de)	1992-07-23	25-hydroxy-vitamin-d3-derivate.
NL191709C (nl)	1996-04-02	C8-gesubstitueerde ergolinederivaten alsmede geneesmiddel dat deze derivaten omvat.
FI883963A0 (fi)	1988-08-26	Isoxazol- -karbolinderivat.
AU1903483A (en)	1984-03-22	Fungicidal thiophene derivatives
DE3483294D1 (de)	1990-10-31	Barbitursaeurederivate.
NO883233D0 (no)	1988-07-20	Hydrokanelsyrederivater.
IT8322230A0 (it)	1983-07-26	Carbapenem-derivati fluoroalchilati.
NO165107C (no)	1990-12-27	Fremgangsmaate for fremstilling av pyrido-imidazo-rifamycin-derivater.
NL184146C (nl)	1989-05-01	Farmaceutisch preparaat dat een vinca-alkaloide bevat.
DE3861208D1 (de)	1991-01-17	Hydroxyalkyl-triazolyl-derivate.
ATE34749T1 (de)	1988-06-15	Acridanon-derivate.
DE3866371D1 (de)	1992-01-09	Diphenylaethylen-derivate.
FI881906A (fi)	1988-10-25	Saett och anordning foer renovering av en fraon en vaegg utskjutande, armerad betongplatta.
DE3868364D1 (de)	1992-03-26	Ucy-1003-derivate.
DE3863447D1 (de)	1991-08-08	Aminoethylphosphinsaeure-derivate.
DE3881146D1 (de)	1993-06-24	Thiazetidin-derivate.

Legal Events

Date	Code	Title	Description
1985-01-01	A85	Still pending on 85-01-01
1987-04-01	BA	A request for search or an international-type search has been filed
1987-04-01	BB	A search report has been drawn up
1987-05-04	BC	A request for examination has been filed
1999-01-04	V1	Lapsed because of non-payment of the annual fee	Effective date: 19981101