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MXPA04006811A - Variantes de proteasa substituidas con multiplos. - Google Patents

Variantes de proteasa substituidas con multiplos.

Info

Publication number
MXPA04006811A
MXPA04006811A MXPA04006811A MXPA04006811A MXPA04006811A MX PA04006811 A MXPA04006811 A MX PA04006811A MX PA04006811 A MXPA04006811 A MX PA04006811A MX PA04006811 A MXPA04006811 A MX PA04006811A MX PA04006811 A MXPA04006811 A MX PA04006811A
Authority
MX
Mexico
Prior art keywords
protease
amino acid
precursor
naturally
occurring
Prior art date
Application number
MXPA04006811A
Other languages
English (en)
Inventor
J Poulose Ayrookaran
Original Assignee
Genencor Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genencor Int filed Critical Genencor Int
Publication of MXPA04006811A publication Critical patent/MXPA04006811A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21062—Subtilisin (3.4.21.62)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Se describen variantes novedosas de proteasa derivadas de secuencias de ADN de proteasas que se presentan naturalmente o proteasas no humanas recombinantes. Las proteasas variantes en general, se obtienen por la modificacion in vitro de una secuencia precursora de ADN que codifica la proteasa que se presenta naturalmente o la proteasa recombinante, para generar la substitucion de una pluralidad de residuos de aminoacidos en la secuencia de aminoacidos de una proteasa precursora. Tales variantes de proteasa tienen propiedades que son diferentes de aquellas de la proteasa precursora tal como un desempeno de lavado alterado. El residuo substituido de aminoacidos equivalente a las composiciones 7, 23, 26, 28, 29, 30, 31, 47, 66, 69, 73, 82, 85, 88, 90, 92, 93, 105, 113, 139, 148, 149, 150, 151, 178, 200, 201, 231, 233, 267 y/o 273 de la subtilisina de Bacillus amyloliquefaciens.
MXPA04006811A 2002-01-16 2003-01-16 Variantes de proteasa substituidas con multiplos. MXPA04006811A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35022102P 2002-01-16 2002-01-16
PCT/US2003/001447 WO2003062380A2 (en) 2002-01-16 2003-01-16 Multiply-substituted protease variants

Publications (1)

Publication Number Publication Date
MXPA04006811A true MXPA04006811A (es) 2004-10-11

Family

ID=27613371

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04006811A MXPA04006811A (es) 2002-01-16 2003-01-16 Variantes de proteasa substituidas con multiplos.

Country Status (8)

Country Link
US (5) US20050170488A1 (es)
EP (3) EP2287321B1 (es)
JP (4) JP5328002B2 (es)
AU (1) AU2003210551A1 (es)
BR (1) BR0306956A (es)
CA (1) CA2472723C (es)
MX (1) MXPA04006811A (es)
WO (1) WO2003062380A2 (es)

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EP3608403A3 (en) * 2014-12-15 2020-03-25 Henkel AG & Co. KGaA Detergent composition comprising subtilase variants
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FI3419991T3 (fi) 2016-03-04 2023-01-31 Modifioidut ribosomaaliset promoottorit proteiinien tuottamiseksi mikro-organismeissa
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JP7010367B2 (ja) 2018-03-26 2022-01-26 日本電気株式会社 通報装置、通報方法、通報システム、及びプログラム

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Also Published As

Publication number Publication date
US20130157341A1 (en) 2013-06-20
WO2003062380A3 (en) 2005-03-24
EP2287320B1 (en) 2014-10-01
JP2013116110A (ja) 2013-06-13
AU2003210551A1 (en) 2003-09-02
JP2015198660A (ja) 2015-11-12
JP6792524B2 (ja) 2020-11-25
JP2017225449A (ja) 2017-12-28
EP2287321B1 (en) 2014-08-13
EP1530631A2 (en) 2005-05-18
EP1530631B1 (en) 2013-08-07
CA2472723C (en) 2013-12-17
JP5863679B2 (ja) 2016-02-17
EP1530631A4 (en) 2006-03-08
US20180155702A1 (en) 2018-06-07
CA2472723A1 (en) 2003-07-31
JP2005529584A (ja) 2005-10-06
WO2003062380A2 (en) 2003-07-31
EP2287321A1 (en) 2011-02-23
JP5328002B2 (ja) 2013-10-30
EP2287320A1 (en) 2011-02-23
BR0306956A (pt) 2006-04-11
US20150232829A1 (en) 2015-08-20
US20120052553A1 (en) 2012-03-01
US20050170488A1 (en) 2005-08-04

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