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MXPA04004567A - Compuestos y composiciones de fenoxi amina para adminstrar agentes activos. - Google Patents

Compuestos y composiciones de fenoxi amina para adminstrar agentes activos.

Info

Publication number
MXPA04004567A
MXPA04004567A MXPA04004567A MXPA04004567A MXPA04004567A MX PA04004567 A MXPA04004567 A MX PA04004567A MX PA04004567 A MXPA04004567 A MX PA04004567A MX PA04004567 A MXPA04004567 A MX PA04004567A MX PA04004567 A MXPA04004567 A MX PA04004567A
Authority
MX
Mexico
Prior art keywords
compositions
active agents
amine compounds
delivering active
phenoxy amine
Prior art date
Application number
MXPA04004567A
Other languages
English (en)
Inventor
Zhu Chen
Original Assignee
Emisphere Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Emisphere Tech Inc filed Critical Emisphere Tech Inc
Publication of MXPA04004567A publication Critical patent/MXPA04004567A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Se proporcionan compuestos y composiciones de fenoxi amina para la administracion de agentes activos. Tambien se proporcionan metodos de administracion y preparacion.
MXPA04004567A 2001-11-13 2002-11-13 Compuestos y composiciones de fenoxi amina para adminstrar agentes activos. MXPA04004567A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35048801P 2001-11-13 2001-11-13
US35728802P 2002-02-15 2002-02-15
PCT/US2002/036552 WO2003045306A2 (en) 2001-11-13 2002-11-13 Phenoxy amine compounds and compositions for delivering active agents

Publications (1)

Publication Number Publication Date
MXPA04004567A true MXPA04004567A (es) 2004-09-10

Family

ID=26996636

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04004567A MXPA04004567A (es) 2001-11-13 2002-11-13 Compuestos y composiciones de fenoxi amina para adminstrar agentes activos.

Country Status (13)

Country Link
US (1) US7297794B2 (es)
EP (1) EP1453816B1 (es)
JP (1) JP4602668B2 (es)
CN (1) CN1596248B (es)
AU (1) AU2002360387B2 (es)
BR (1) BR0214199A (es)
CA (1) CA2465641C (es)
ES (1) ES2431630T3 (es)
HK (1) HK1069383A1 (es)
MX (1) MXPA04004567A (es)
NZ (1) NZ532597A (es)
WO (1) WO2003045306A2 (es)
ZA (1) ZA200403572B (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7297794B2 (en) 2001-11-13 2007-11-20 Emisphere Technologies, Inc. Phenoxy amine compounds and compositions for delivering active agents
WO2003072195A2 (en) 2002-02-20 2003-09-04 Eli Lilly And Company Method for administering glp-1 molecules
US20040076587A1 (en) * 2002-06-19 2004-04-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmaceutical composition for intranasal administration containing a CGRP antagonist
NZ539218A (en) * 2002-09-18 2008-03-28 Univ Montreal Ct Hospitalier Chum Synthetic GHRH analogues of 29 amino acids or more
BRPI0509411A (pt) 2004-04-16 2007-09-04 Emisphere Tech Inc método para tratar doença maligna, hipercalcemia de malignidade e metástases ósseas osteolìticas, sal de mesilato, composição e método de administração de agente ativo e bisfosfonato
ES2586423T3 (es) 2004-05-14 2016-10-14 Emisphere Technologies, Inc. Compuestos de aril cetona y composiciones para administrar principios activos
JP5254610B2 (ja) 2004-05-14 2013-08-07 エミスフェアー・テクノロジーズ・インク 活性薬剤を送達するための化合物および組成物
NZ551455A (en) 2004-05-19 2012-03-30 Emisphere Tech Inc Acyclovir formulations
CN1968704B (zh) 2004-05-19 2010-12-08 爱密斯菲尔科技公司 局部用色甘酸制剂
US9345725B2 (en) 2004-12-29 2016-05-24 Emisphere Technologies, Inc. Pharmaceutical formulations of gallium salts
WO2006076692A1 (en) 2005-01-12 2006-07-20 Emisphere Technologies, Inc. Compositions for buccal delivery of parathyroid hormone
US8975227B2 (en) 2005-07-15 2015-03-10 Emisphere Technologies, Inc. Intraoral dosage forms of glucagon
CA2626029A1 (en) * 2005-11-04 2007-05-18 Genta Incorporated Pharmaceutical gallium compositions and methods
EP1986646A1 (en) * 2006-02-15 2008-11-05 Sanofi-Aventis Novel azacycly-substituted arylthienopyrimidinones, process for their preparation and their use as medicaments
AU2007214710A1 (en) * 2006-02-15 2007-08-23 Sanofi-Aventis Novel amino alcohol-substituted arylthienopyrimidinones, process for their preparation and their use as medicaments
JP4857138B2 (ja) * 2006-03-23 2012-01-18 富士フイルム株式会社 レジスト組成物及びそれを用いたパターン形成方法
WO2007121318A2 (en) 2006-04-12 2007-10-25 Emisphere Technologies, Inc. Formulations for delivering insulin
ES2538254T3 (es) 2006-04-18 2015-06-18 Emisphere Technologies, Inc. Agentes de administración de dialquil éter
WO2008003050A2 (en) 2006-06-28 2008-01-03 Emisphere Technologies, Inc. Gallium nitrate formulations
CA2661018C (en) 2006-08-18 2015-11-24 Emisphere Technologies, Inc. Synthesis of propyl phenoxy ethers and use as delivery agents
US8895777B2 (en) * 2006-08-31 2014-11-25 Emisphere Technologies Inc Compounds and compositions for delivering active agents
US8383852B2 (en) * 2007-02-16 2013-02-26 Emisphere Technologies, Inc. Compounds having a cyclic moiety and compositions for delivering active agents
US20110039930A1 (en) 2009-08-03 2011-02-17 Emisphere Technologies, Inc. Fast-acting naproxen composition with reduced gastrointestinal effects
MX368045B (es) * 2012-08-23 2019-09-17 Emisphere Tech Inc Compuestos de diisopropanolamina y dietanolamina de fenoxialquilo para la administracion de agentes activos.
PL2897620T3 (pl) 2012-09-21 2020-11-02 Intensity Therapeutics, Inc Sposób leczenia nowotworu złośliwego
CA3011657A1 (en) 2015-02-09 2016-08-18 Entera Bio Ltd. Formulations for oral administration of active agents
CN104961687B (zh) * 2015-06-03 2017-07-25 苏州维泰生物技术有限公司 1,2‑二嗪衍生物及其制剂、用途

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH297705A (de) * 1950-09-16 1954-03-31 Cilag Ag Verfahren zur Herstellung eines neuen basischen Äthers.
GB710511A (en) * 1950-09-29 1954-06-16 Abbott Lab Improvements in or relating to aryl ethers of morpholino-alkanols and methods for the production thereof
GB1524260A (en) 1976-11-23 1978-09-06 Beecham Group Ltd Aminoalkyloneoxyd substituted 4-hydroxy-3 nitrocoumarins
JPS58113178A (ja) 1981-12-28 1983-07-05 Yamanouchi Pharmaceut Co Ltd 「お」−（１−イミダゾリル）アルキルオキシ（またはチオ）ベンゼン誘導体
US4851423A (en) 1986-12-10 1989-07-25 Schering Corporation Pharmaceutically active compounds
CA1315279C (en) * 1987-01-12 1993-03-30 Nancy Grace Bollinger Anti-inflammatory agents
US5023253A (en) * 1987-12-21 1991-06-11 University Patents, Inc. 6-substituted mitomycin analogs
IE902465A1 (en) * 1989-07-07 1991-02-13 Schering Corp Pharmaceutically active compounds
JPH0441472A (ja) 1990-06-05 1992-02-12 Sankyo Co Ltd グアニジノ安息香酸エステル誘導体
JPH04117461A (ja) * 1990-09-07 1992-04-17 Asahi Denka Kogyo Kk 耐光性の改善された高分子材料組成物
JP2000256286A (ja) * 1999-03-11 2000-09-19 Kaken Pharmaceut Co Ltd アルキルアミン誘導体
JP5117658B2 (ja) 1999-11-05 2013-01-16 エミスフェアー・テクノロジーズ・インク フェノキシカルボン酸化合物及び活性剤を送達するための組成物
US7297794B2 (en) 2001-11-13 2007-11-20 Emisphere Technologies, Inc. Phenoxy amine compounds and compositions for delivering active agents
BRPI0509411A (pt) * 2004-04-16 2007-09-04 Emisphere Tech Inc método para tratar doença maligna, hipercalcemia de malignidade e metástases ósseas osteolìticas, sal de mesilato, composição e método de administração de agente ativo e bisfosfonato
US9345725B2 (en) 2004-12-29 2016-05-24 Emisphere Technologies, Inc. Pharmaceutical formulations of gallium salts

Also Published As

Publication number Publication date
ES2431630T3 (es) 2013-11-27
HK1069383A1 (en) 2005-05-20
NZ532597A (en) 2006-04-28
EP1453816A4 (en) 2005-02-09
CN1596248B (zh) 2012-05-09
WO2003045306A2 (en) 2003-06-05
US20050119502A1 (en) 2005-06-02
EP1453816A2 (en) 2004-09-08
US7297794B2 (en) 2007-11-20
ZA200403572B (en) 2005-09-28
WO2003045306A3 (en) 2003-09-04
JP2005519875A (ja) 2005-07-07
AU2002360387B2 (en) 2008-08-07
BR0214199A (pt) 2005-01-04
CA2465641A1 (en) 2003-06-05
AU2002360387A1 (en) 2003-06-10
JP4602668B2 (ja) 2010-12-22
EP1453816B1 (en) 2013-09-18
CN1596248A (zh) 2005-03-16
CA2465641C (en) 2011-06-21

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Legal Events

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