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MX9709962A - Somatostatin peptides. - Google Patents

Somatostatin peptides.

Info

Publication number
MX9709962A
MX9709962A MX9709962A MX9709962A MX9709962A MX 9709962 A MX9709962 A MX 9709962A MX 9709962 A MX9709962 A MX 9709962A MX 9709962 A MX9709962 A MX 9709962A MX 9709962 A MX9709962 A MX 9709962A
Authority
MX
Mexico
Prior art keywords
residue
ala
amino acid
alpha
lys
Prior art date
Application number
MX9709962A
Other languages
Spanish (es)
Inventor
Rainer Albert
Wilfried Bauer
Christian Bruns
Nagarajan Chandramouli
Ian Lewis
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Priority claimed from PCT/EP1996/002840 external-priority patent/WO1997001579A2/en
Publication of MX9709962A publication Critical patent/MX9709962A/en

Links

Landscapes

  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Somatostatin analogues comprising the amino acid sequence of the formula (I): -(D/L)Trp-Lys-X1-X2, wherein X1 is a substituted Thr, Ser, Tyr, Glu or Cys residue and X2 is an 'alpha'-amino acid having an aromatic residue on the C'alpha' side chain, or an amino acid unit selected from Dab, Dpr, Dpm, His (Bzl)HyPro, thienyl-Ala, cyclohexyl-Ala and t.-butyl-Ala, the residue Lys of said sequence corresponding to the residue Lys9 of the native somatostatin-14, in free form, in salt form or complexed with a detectable element have interesting pharmacological properties.
MX9709962A 1995-06-29 1996-06-28 Somatostatin peptides. MX9709962A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9513224.7A GB9513224D0 (en) 1995-06-29 1995-06-29 Organic compounds
PCT/EP1996/002840 WO1997001579A2 (en) 1995-06-29 1996-06-28 Somatostatin peptides

Publications (1)

Publication Number Publication Date
MX9709962A true MX9709962A (en) 1998-03-31

Family

ID=10776842

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9709962A MX9709962A (en) 1995-06-29 1996-06-28 Somatostatin peptides.

Country Status (7)

Country Link
AR (1) AR004497A1 (en)
CO (1) CO4700528A1 (en)
GB (1) GB9513224D0 (en)
HK (1) HK1014964A1 (en)
MX (1) MX9709962A (en)
RU (1) RU2160741C2 (en)
ZA (1) ZA965538B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2168983A1 (en) 2008-09-30 2010-03-31 Ipsen Pharma New octapeptide compounds and their therapeutic use
US20100151033A1 (en) * 2008-12-15 2010-06-17 Novartis Ag Octreotide depot formulation with constantly high exposure levels
RU2457215C1 (en) * 2011-04-07 2012-07-27 Закрытое Акционерное Общество "Фарм-Синтез" Octapeptide for producing radiotracers, radiotracer based thereon method of diagnosing tumours, expressing somatostatin receptors
RU2528414C1 (en) * 2013-01-25 2014-09-20 Закрытое Акционерное Общество "Фарм-Синтез" Cyclic octapeptide, radiopharmaceutical agent based thereon and method of using radiopharmaceutical agent to produce medicinal (pharmaceutical) agents for treating neoplasms expressing somatostatin receptors

Also Published As

Publication number Publication date
ZA965538B (en) 1997-12-29
HK1014964A1 (en) 1999-10-08
GB9513224D0 (en) 1995-09-06
AR004497A1 (en) 1998-12-16
RU2160741C2 (en) 2000-12-20
CO4700528A1 (en) 1998-12-29

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