MX9303246A - NOVEL PHOSPHONOCARBOXYLATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING ABNORMAL METABOLISM OF CALCIUM AND PHOSPHATE. - Google Patents
NOVEL PHOSPHONOCARBOXYLATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING ABNORMAL METABOLISM OF CALCIUM AND PHOSPHATE.Info
- Publication number
- MX9303246A MX9303246A MX9303246A MX9303246A MX9303246A MX 9303246 A MX9303246 A MX 9303246A MX 9303246 A MX9303246 A MX 9303246A MX 9303246 A MX9303246 A MX 9303246A MX 9303246 A MX9303246 A MX 9303246A
- Authority
- MX
- Mexico
- Prior art keywords
- phosphate
- calcium
- novel
- methods
- pharmaceutical compositions
- Prior art date
Links
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 title abstract 2
- 229910019142 PO4 Inorganic materials 0.000 title abstract 2
- 229910052791 calcium Inorganic materials 0.000 title abstract 2
- 239000011575 calcium Substances 0.000 title abstract 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 title abstract 2
- 239000010452 phosphate Substances 0.000 title abstract 2
- ZJAOAACCNHFJAH-UHFFFAOYSA-N phosphonoformic acid Chemical class OC(=O)P(O)(O)=O ZJAOAACCNHFJAH-UHFFFAOYSA-N 0.000 title abstract 2
- 208000021959 Abnormal metabolism Diseases 0.000 title 1
- 230000006371 metabolic abnormality Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere adicionalmente a fosfonocarboxilatos novedosos y sus sales farmacéuticamente aceptables. Finalmente, la presente invención se refiere a métodos para tratar o prevenir condiciones patológicas, caracterizadas por metabolismo normal del calcio y el fosfato humanos u otros mamíferos. Este método comprende administrar a un humano u otro mamífero que necesite de dicho tratamiento, una cantidad segura y efectiva de un compuesto o composición de la presente invención.The present invention further relates to novel phosphonocarboxylates and their pharmaceutically acceptable salts. Finally, the present invention relates to methods for treating or preventing pathological conditions, characterized by normal metabolism of calcium and phosphate in humans or other mammals. This method comprises administering to a human or other mammal in need of such treatment, a safe and effective amount of a compound or composition of the present invention.
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89088592A | 1992-05-29 | 1992-05-29 | |
| US89130992A | 1992-05-29 | 1992-05-29 | |
| US89135592A | 1992-05-29 | 1992-05-29 | |
| US89148792A | 1992-05-29 | 1992-05-29 | |
| US89088692A | 1992-05-29 | 1992-05-29 | |
| US89149092A | 1992-05-29 | 1992-05-29 | |
| US08/055,810 US5760021A (en) | 1992-05-29 | 1993-05-07 | Phosphonocarboxylate compounds pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9303246A true MX9303246A (en) | 1994-05-31 |
Family
ID=27568102
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9303246A MX9303246A (en) | 1992-05-29 | 1993-05-31 | NOVEL PHOSPHONOCARBOXYLATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING ABNORMAL METABOLISM OF CALCIUM AND PHOSPHATE. |
Country Status (4)
| Country | Link |
|---|---|
| CN (2) | CN1048017C (en) |
| IL (3) | IL119243A (en) |
| MX (1) | MX9303246A (en) |
| MY (1) | MY131438A (en) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL77243A (en) * | 1984-12-21 | 1996-11-14 | Procter & Gamble | Pharmaceutical compositions containing geminal diphosphonic acid compounds and certain such novel compounds |
| IL86951A (en) * | 1987-07-06 | 1996-07-23 | Procter & Gamble Pharma | Methylene phosphonoalkyl-phosphinates and pharmaceutical compositions containing them |
-
1993
- 1993-05-28 IL IL11924393A patent/IL119243A/en not_active IP Right Cessation
- 1993-05-28 IL IL105838A patent/IL105838A/en not_active IP Right Cessation
- 1993-05-28 MY MYPI93001058A patent/MY131438A/en unknown
- 1993-05-29 CN CN93108223A patent/CN1048017C/en not_active Expired - Fee Related
- 1993-05-31 MX MX9303246A patent/MX9303246A/en not_active IP Right Cessation
-
1996
- 1996-09-12 IL IL11924396A patent/IL119243A0/en unknown
-
1999
- 1999-01-30 CN CN99101839.7A patent/CN1230409A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN1230409A (en) | 1999-10-06 |
| IL119243A0 (en) | 1996-12-05 |
| IL119243A (en) | 2002-11-10 |
| CN1048017C (en) | 2000-01-05 |
| IL105838A0 (en) | 1993-09-22 |
| MY131438A (en) | 2007-08-30 |
| CN1089613A (en) | 1994-07-20 |
| IL105838A (en) | 1998-03-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration | ||
| MM | Annulment or lapse due to non-payment of fees |