MX9206628A - Ester de prolinaboronato y metodo para su preparacion. - Google Patents

Ester de prolinaboronato y metodo para su preparacion.

Info

Publication number: MX9206628A
Authority: MX; Mexico
Prior art keywords: prolinaboronate; ester; preparation; prolinaboronate ester
Prior art date: 1991-11-22

Application number

MX9206628A

Other languages

English (en)

Inventor

Roger Snow

Terence A Kelly

Julian Adams

Simon Coutts

Clark Perry

Original Assignee

Boehringer Ingelheim Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-11-22

Filing date

1992-11-18

Publication date

1993-05-01

1992-11-18 Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma

1993-05-01 Publication of MX9206628A publication Critical patent/MX9206628A/es

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pyrrole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

MX9206628A 1991-11-22 1992-11-18 Ester de prolinaboronato y metodo para su preparacion. MX9206628A (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US79614891A	1991-11-22	1991-11-22
US93619892A	1992-08-26	1992-08-26

Publications (1)

Publication Number	Publication Date
MX9206628A true MX9206628A (es)	1993-05-01

Family

ID=27121696

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MX9206628A MX9206628A (es)	1991-11-22	1992-11-18	Ester de prolinaboronato y metodo para su preparacion.

Country Status (17)

Country	Link
EP (1)	EP0641347A1 (es)
JP (1)	JPH07501078A (es)
CN (1)	CN1073946A (es)
AU (1)	AU661362B2 (es)
CA (1)	CA2123128A1 (es)
CZ (1)	CZ124494A3 (es)
FI (1)	FI942345A0 (es)
HU (1)	HUT67937A (es)
IL (1)	IL103817A0 (es)
MX (1)	MX9206628A (es)
NO (1)	NO941905L (es)
NZ (1)	NZ245207A (es)
PT (1)	PT101079A (es)
SI (1)	SI9200332A (es)
SK (1)	SK59294A3 (es)
TW (1)	TW232697B (es)
WO (1)	WO1993010127A1 (es)

Families Citing this family (44)

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US6825169B1 (en)	1991-10-22	2004-11-30	Trustees Of Tufts College	Inhibitors of dipeptidyl-aminopeptidase type IV
US5965532A (en)	1996-06-28	1999-10-12	Trustees Of Tufts College	Multivalent compounds for crosslinking receptors and uses thereof
US6100234A (en) *	1997-05-07	2000-08-08	Tufts University	Treatment of HIV
US6040145A (en)	1997-05-07	2000-03-21	Tufts University	Potentiation of the immune response
TR200000815T2 (tr)	1997-09-29	2000-12-21	Point Therapeutics Inc.	In vitro hematopoietik hücrelerin stimulasyonu.
BR9910251A (pt)	1998-05-04	2001-01-02	Point Therapeutics Inc	Estimulação hematopoiética
BR9910907A (pt)	1998-06-05	2002-02-13	Point Therapeutics Inc	Compostos cìclicos de boroprolina
US6979697B1 (en)	1998-08-21	2005-12-27	Point Therapeutics, Inc.	Regulation of substrate activity
US6890904B1 (en)	1999-05-25	2005-05-10	Point Therapeutics, Inc.	Anti-tumor agents
EP1259246A2 (en) *	2000-02-25	2002-11-27	Novo Nordisk A/S	Use of dpp-iv inhibitors for the treatment of diabetes
WO2003063903A2 (en) *	2002-02-01	2003-08-07	Probiodrug Ag	Modulation of t lymphocytes using dp iv inhibitors
EA013684B1 (ru) *	2003-11-12	2010-06-30	Феномикс Корпорейшн	Гетероциклические соединения бороновой кислоты
US7317109B2 (en)	2003-11-12	2008-01-08	Phenomix Corporation	Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
US7767828B2 (en)	2003-11-12	2010-08-03	Phenomix Corporation	Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
US7576121B2 (en)	2003-11-12	2009-08-18	Phenomix Corporation	Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
AU2004290897B2 (en)	2003-11-17	2009-02-26	Novartis Ag	Use of dipeptidyl peptidase IV inhibitors
BR122018073405B1 (pt)	2004-01-20	2023-04-25	Novartis Ag	Comprimido farmacêutico produzido por compressão direta compreendendo inibidor de dipeptidilpeptidase iv
AR049631A1 (es) *	2004-04-27	2006-08-23	Wyeth Corp	Proceso de acoplamiento para la generacion de derivados reactivos de pirrol -2- carbonitrilo n- sustituidos con contenido de boro para producir biarilos
DOP2006000008A (es)	2005-01-10	2006-08-31	Arena Pharm Inc	Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1
JP2008545661A (ja)	2005-05-19	2008-12-18	ジェネンテック・インコーポレーテッド	線維芽細胞活性化タンパク質阻害剤化合物および
US7825139B2 (en)	2005-05-25	2010-11-02	Forest Laboratories Holdings Limited (BM)	Compounds and methods for selective inhibition of dipeptidyl peptidase-IV
CN1331835C (zh) *	2005-10-18	2007-08-15	武汉大学	光活性β－羟基酮的制备方法
WO2007100374A2 (en) *	2005-12-19	2007-09-07	Trustees Of Tufts College	Soft protease inhibitors and pro-soft forms thereof
PE20071221A1 (es)	2006-04-11	2007-12-14	Arena Pharm Inc	Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas
SG10201404220TA (en)	2006-04-11	2014-10-30	Arena Pharm Inc	Methods of using gpr119 receptor to identify compounds useful for increasing bone mass in an individual
EP2108960A1 (en)	2008-04-07	2009-10-14	Arena Pharmaceuticals, Inc.	Methods of using A G protein-coupled receptor to identify peptide YY (PYY) secretagogues and compounds useful in the treatment of conditons modulated by PYY
CN103497232A (zh) *	2008-06-17	2014-01-08	米伦纽姆医药公司	硼酸酯化合物及其医药组合物
AR077642A1 (es)	2009-07-09	2011-09-14	Arena Pharm Inc	Moduladores del metabolismo y el tratamiento de trastornos relacionados con el mismo
WO2011127051A1 (en)	2010-04-06	2011-10-13	Arena Pharmaceuticals, Inc.	Modulators of the gpr119 receptor and the treatment of disorders related thereto
CA2812061A1 (en)	2010-09-22	2012-03-29	Arena Pharmaceuticals, Inc.	Modulators of the gpr119 receptor and the treatment of disorders related thereto
US20140018371A1 (en)	2011-04-01	2014-01-16	Arena Pharmaceuticals, Inc.	Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
WO2012145361A1 (en)	2011-04-19	2012-10-26	Arena Pharmaceuticals, Inc.	Modulators of the gpr119 receptor and the treatment of disorders related thereto
US20140038889A1 (en)	2011-04-22	2014-02-06	Arena Pharmaceuticals, Inc.	Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
WO2012145604A1 (en)	2011-04-22	2012-10-26	Arena Pharmaceuticals, Inc.	Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2012170702A1 (en)	2011-06-08	2012-12-13	Arena Pharmaceuticals, Inc.	Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2013055910A1 (en)	2011-10-12	2013-04-18	Arena Pharmaceuticals, Inc.	Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2014074668A1 (en)	2012-11-08	2014-05-15	Arena Pharmaceuticals, Inc.	Modulators of gpr119 and the treatment of disorders related thereto
US9523687B2 (en)	2014-02-28	2016-12-20	Institut Pasteur	Levels of CXCL 10/IP-10 forms and soluble CD26/DPPIV activity as early predictive biomarkers for HIV/SIV associated mucosal inflammation and progression towards AIDS
SG11201609259VA (en)	2014-05-20	2016-12-29	Millennium Pharm Inc	Boron-containing proteasome inhibitors for use after primary cancer therapy
MX2017011586A (es)	2015-03-09	2017-10-26	Intekrin Therapeutics Inc	Metodos para el tratamiento de enfermedad de higado graso no alcoholico y/o lipodistrofia.
WO2018162722A1 (en)	2017-03-09	2018-09-13	Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke	Dpp-4 inhibitors for use in treating bone fractures
CN110996951A (zh)	2017-04-03	2020-04-10	科赫罗斯生物科学股份有限公司	治疗进行性核上性麻痹的PPARγ激动剂
CN108047257B (zh) *	2017-12-17	2020-03-13	沧州普瑞东方科技有限公司	一种手性n-boc-吡咯烷-2-硼酸的制备工艺
CN110452258B (zh) *	2019-09-03	2021-01-01	上海馨远医药科技有限公司	一种二肽缬氨酸硼脯氨酸盐的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4935493A (en) *	1987-10-06	1990-06-19	E. I. Du Pont De Nemours And Company	Protease inhibitors
DK0528858T3 (da) *	1990-04-14	1997-07-28	Univ Tufts Med	Inhibitorer af dipeptidyl-aminopeptidase type IV
GB9017694D0 (en) *	1990-08-13	1990-09-26	Sandoz Ltd	Improvements in or relating to organic chemistry

1992
- 1992-11-18 MX MX9206628A patent/MX9206628A/es unknown
- 1992-11-19 EP EP92925238A patent/EP0641347A1/en not_active Withdrawn
- 1992-11-19 AU AU31368/93A patent/AU661362B2/en not_active Expired - Fee Related
- 1992-11-19 CZ CZ941244A patent/CZ124494A3/cs unknown
- 1992-11-19 SI SI19929200332A patent/SI9200332A/sl unknown
- 1992-11-19 SK SK592-94A patent/SK59294A3/sk unknown
- 1992-11-19 PT PT101079A patent/PT101079A/pt not_active Application Discontinuation
- 1992-11-19 HU HU9401350A patent/HUT67937A/hu unknown
- 1992-11-19 JP JP5509442A patent/JPH07501078A/ja active Pending
- 1992-11-19 WO PCT/US1992/009845 patent/WO1993010127A1/en not_active Application Discontinuation
- 1992-11-19 CA CA002123128A patent/CA2123128A1/en not_active Abandoned
- 1992-11-20 IL IL103817A patent/IL103817A0/xx unknown
- 1992-11-20 TW TW081109304A patent/TW232697B/zh active
- 1992-11-20 NZ NZ24520792A patent/NZ245207A/en unknown
- 1992-11-23 CN CN92113215A patent/CN1073946A/zh active Pending
1994
- 1994-05-20 NO NO941905A patent/NO941905L/no unknown
- 1994-05-20 FI FI942345A patent/FI942345A0/fi not_active Application Discontinuation

Also Published As

Publication number	Publication date
PT101079A (pt)	1994-02-28
JPH07501078A (ja)	1995-02-02
IL103817A0 (en)	1993-04-04
EP0641347A1 (en)	1995-03-08
HUT67937A (en)	1995-05-29
AU661362B2 (en)	1995-07-20
CZ124494A3 (en)	1995-07-12
NO941905L (no)	1994-07-14
SK59294A3 (en)	1995-02-08
AU3136893A (en)	1993-06-15
TW232697B (es)	1994-10-21
CA2123128A1 (en)	1993-05-27
FI942345A (fi)	1994-05-20
HU9401350D0 (en)	1994-08-29
NZ245207A (en)	1994-07-26
FI942345A0 (fi)	1994-05-20
WO1993010127A1 (en)	1993-05-27
NO941905D0 (no)	1994-05-20
SI9200332A (en)	1993-06-30
CN1073946A (zh)	1993-07-07

Publication	Publication Date	Title
MX9206628A (es)	1993-05-01	Ester de prolinaboronato y metodo para su preparacion.
MX9201355A (es)	1992-10-01	Bis-naftal imidas y metodo para su preparacion.
MX24568A (es)	1993-09-01	3-arilcarbonil-1h-indoles y procedimiento para su preparacion.
MX9205032A (es)	1993-05-01	1,2-dihidro-2-oxo-piridinas y procedimiento para su preparacion.
MX26267A (es)	1993-09-01	Aminobenzodiacepinas y procedimiento para su prepaacion.
MX9202022A (es)	1992-11-01	Derivados de pirazina y proceso para su preparacion.
MX9102719A (es)	1992-06-01	Aparato y metodo para generar señales de cuadratura.
NO921218D0 (no)	1992-03-27	Reseptor-rensemetode
MX9204920A (es)	1993-02-01	Cianofenilpirroles y procedimiento para su obtencion.
MX9201780A (es)	1992-10-01	Eteres oximicos y procedimiento para su preparacion.
MX9203836A (es)	1993-01-01	Derivados de acido-4-amino-3-hidroxicarboxilico y proceso para su preparacion.
MX9205747A (es)	1993-04-01	Pirazolinas y procedimiento para su preparacion.
MX21243A (es)	1994-01-31	Indenoindoles y procedimiento para su preparacion.
MX9205746A (es)	1993-04-01	Pirazolinas y procedimiento para su preparacion.
MX9100811A (es)	1992-04-01	Indolonaftiridinas y procedimiento para su preparacion
MX9205821A (es)	1993-04-01	Pirimidinil- y triazinileteres y -tioeteres y procedimiento para su preparacion.
MX9202536A (es)	1992-11-01	Antibioticos tetraciclicos y procedimiento para su preparacion.
FI940403A (fi)	1994-07-30	Elliptisiinijohdannainen ja menetelmä sen valmistamiseksi
MX9205457A (es)	1993-03-01	Nuevos compuestos derivados de mupirocina y procedimiento para su preparacion
MX9204626A (es)	1993-06-01	Mensula de soporte y metodo para su fabricacion.
MX9202605A (es)	1992-12-01	Polimeros lineales y proceso para su preparacion.
MX9202327A (es)	1992-11-01	2-aril pirroles substituidos y procedimiento para su obtencion.
MX9102324A (es)	1992-06-01	Pirimidilamidoximas substituidas y procedimiento para su obtencion.
MX9204843A (es)	1993-04-01	Pirazolinas substituidas y procedimiento para su obtencion.
MX9205346A (es)	1993-04-01	Diazacicloalcanos fosforilados y procedimiento para su obtencion.