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MX9101958A - Inhibidores de acat de urea de aminosulfonilo - Google Patents

Inhibidores de acat de urea de aminosulfonilo

Info

Publication number
MX9101958A
MX9101958A MX9101958A MX9101958A MX9101958A MX 9101958 A MX9101958 A MX 9101958A MX 9101958 A MX9101958 A MX 9101958A MX 9101958 A MX9101958 A MX 9101958A MX 9101958 A MX9101958 A MX 9101958A
Authority
MX
Mexico
Prior art keywords
acat inhibitors
aminosulfonyl
compounds
aminosulfonyl urea
urea acat
Prior art date
Application number
MX9101958A
Other languages
English (en)
Inventor
Joseph Armand Picard
Drago Robert Sliskovic
Ann Arbor
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of MX9101958A publication Critical patent/MX9101958A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/96Sulfur atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C307/00Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C307/04Diamides of sulfuric acids
    • C07C307/06Diamides of sulfuric acids having nitrogen atoms of the sulfamide groups bound to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C307/00Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C307/04Diamides of sulfuric acids
    • C07C307/08Diamides of sulfuric acids having nitrogen atoms of the sulfamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C307/00Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C307/04Diamides of sulfuric acids
    • C07C307/10Diamides of sulfuric acids having nitrogen atoms of the sulfamide groups bound to carbon atoms of six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/10Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/14Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MX9101958A 1990-11-07 1991-11-06 Inhibidores de acat de urea de aminosulfonilo MX9101958A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61028790A 1990-11-07 1990-11-07
US07/747,040 US5214206A (en) 1990-11-07 1991-08-19 Aminosulfonyl urea acat inhibitors

Publications (1)

Publication Number Publication Date
MX9101958A true MX9101958A (es) 1992-07-08

Family

ID=27086230

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9101958A MX9101958A (es) 1990-11-07 1991-11-06 Inhibidores de acat de urea de aminosulfonilo

Country Status (16)

Country Link
US (2) US5214206A (es)
EP (1) EP0556322B1 (es)
JP (2) JP3256541B2 (es)
AT (1) ATE139226T1 (es)
AU (1) AU657928B2 (es)
CA (1) CA2094806C (es)
DE (1) DE69120287T2 (es)
DK (1) DK0556322T3 (es)
ES (1) ES2088128T3 (es)
GR (1) GR3020355T3 (es)
IE (1) IE75379B1 (es)
MX (1) MX9101958A (es)
NZ (1) NZ240481A (es)
PH (1) PH30665A (es)
PT (1) PT99435B (es)
WO (1) WO1992008694A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2098912A1 (en) * 1990-12-28 1992-06-29 Tatsuki Shiota Benzoxa condensed ring compound, process for producing the same and pharmaceutical composition comprising the same
US5576335A (en) * 1994-02-01 1996-11-19 Nisshin Flour Milling Co., Ltd. Urea derivatives and their use as ACAT inhibitors
US5491170A (en) * 1994-12-19 1996-02-13 Warner-Lambert Company β-carboxy sulfonamide ACAT inhibitors
US6103733A (en) * 1998-09-09 2000-08-15 Bachmann; Kenneth A. Method for increasing HDL cholesterol levels using heteroaromatic phenylmethanes
CA2369967A1 (en) * 2001-02-12 2002-08-12 Joseph Anthony Cornicelli Methods of treating nuclear factor-kappa b mediated diseases and disorders
EP1281399A3 (en) * 2001-08-01 2004-02-11 Warner-Lambert Company Dual inhibitors of wax ester and cholesteryl ester synthesis for inhibiting sebum production
ES2677668T3 (es) * 2010-11-16 2018-08-06 Texas Heart Institute Agonistas que mejoran la unión de células que expresan integrina a receptores de integrina
CN103288749A (zh) * 2013-03-04 2013-09-11 盐城工学院 可作除草剂的氨基磺酰脲类化合物
EP3598983A1 (en) * 2014-10-03 2020-01-29 Synaffix B.V. Sulfamide linker, conjugates thereof, and methods of preparation
RS60048B1 (sr) * 2015-02-16 2020-04-30 Univ Queensland Sulfoniluree i srodna jedinjenja i njihova upotreba
MX2018009840A (es) * 2016-02-16 2019-01-21 Univ Queensland Sulfonilureas y compuestos relacionados y sus usos.
KR102669722B1 (ko) 2017-07-07 2024-05-29 인플라좀 리미티드 신규한 설폰아마이드 카복스아마이드 화합물
GB201721185D0 (en) * 2017-12-18 2018-01-31 Nodthera Ltd Sulphonyl urea derivatives
AU2019322546A1 (en) * 2018-08-15 2021-03-04 Inflazome Limited Novel sulfonamideurea compounds
PT3983387T (pt) 2019-06-12 2024-07-10 Nodthera Ltd Derivados de sulfonilurea e seus usos

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2312404A (en) * 1939-11-22 1943-03-02 Haack Erich Method of preparing n-sulphonylureas
CH396872A (de) * 1959-08-13 1965-08-15 Ciba Geigy Verfahren zur Herstellung neuer Harnstoffe
US3242174A (en) * 1962-02-06 1966-03-22 Pfizer & Co C 1-(tertiary aminosulfonyl)-3-(hydrocarbon) ureas
GB990860A (en) * 1962-02-08 1965-05-05 Pfizer & Co C N,n-disubstituted sulfamylureas and compositions thereof
US3245982A (en) * 1962-03-27 1966-04-12 Pfizer & Co C Sulfamylsemicarbazides
DE1518541A1 (de) * 1965-03-16 1969-09-11 Boehringer Mannheim Gmbh Verfahren zur Herstellung von Sulfonylharnstoffen und Sulfonylsemicarbaziden
CH649081A5 (de) * 1982-01-12 1985-04-30 Ciba Geigy Ag Triaza-verbindungen.

Also Published As

Publication number Publication date
US5288757A (en) 1994-02-22
NZ240481A (en) 1994-06-27
JP3256541B2 (ja) 2002-02-12
US5214206A (en) 1993-05-25
JP2001026574A (ja) 2001-01-30
GR3020355T3 (en) 1996-09-30
CA2094806C (en) 2004-11-02
DE69120287T2 (de) 1996-10-10
WO1992008694A1 (en) 1992-05-29
EP0556322A1 (en) 1993-08-25
IE913874A1 (en) 1992-05-20
DK0556322T3 (da) 1996-10-14
PH30665A (en) 1997-09-16
PT99435B (pt) 1999-04-30
IE75379B1 (en) 1997-09-10
ES2088128T3 (es) 1996-08-01
AU657928B2 (en) 1995-03-30
JPH06501707A (ja) 1994-02-24
DE69120287D1 (en) 1996-07-18
PT99435A (pt) 1992-12-31
CA2094806A1 (en) 1992-05-08
ATE139226T1 (de) 1996-06-15
AU8959791A (en) 1992-06-11
EP0556322B1 (en) 1996-06-12

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees