MX366405B - Uso de peptidos glp-1 de accion prolongada. - Google Patents
Uso de peptidos glp-1 de accion prolongada.Info
- Publication number
- MX366405B MX366405B MX2014014946A MX2014014946A MX366405B MX 366405 B MX366405 B MX 366405B MX 2014014946 A MX2014014946 A MX 2014014946A MX 2014014946 A MX2014014946 A MX 2014014946A MX 366405 B MX366405 B MX 366405B
- Authority
- MX
- Mexico
- Prior art keywords
- peptides
- long
- acting glp
- glp
- acting
- Prior art date
Links
- 101100337060 Caenorhabditis elegans glp-1 gene Proteins 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 102400000322 Glucagon-like peptide 1 Human genes 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
La presente invención se refiere a uso de péptidos GLP-1 de acción prolongada en ciertos regímenes de dosificación para el tratamiento de diabetes tipo 2, obesidad, etc.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12174535 | 2012-07-01 | ||
US201261694837P | 2012-08-30 | 2012-08-30 | |
US201261708162P | 2012-10-01 | 2012-10-01 | |
EP12186781 | 2012-10-01 | ||
PCT/EP2013/063004 WO2014005858A1 (en) | 2012-07-01 | 2013-06-21 | Use of long-acting glp-1 peptides |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014014946A MX2014014946A (es) | 2015-04-08 |
MX366405B true MX366405B (es) | 2019-07-08 |
Family
ID=49881374
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014014946A MX366405B (es) | 2012-07-01 | 2013-06-21 | Uso de peptidos glp-1 de accion prolongada. |
MX2020010693A MX2020010693A (es) | 2012-07-01 | 2014-12-05 | Uso de peptidos glp-1 de accion prolongada. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020010693A MX2020010693A (es) | 2012-07-01 | 2014-12-05 | Uso de peptidos glp-1 de accion prolongada. |
Country Status (11)
Country | Link |
---|---|
US (2) | US9764003B2 (es) |
EP (3) | EP4406593A3 (es) |
JP (1) | JP6059802B2 (es) |
AU (3) | AU2013286177B2 (es) |
BR (1) | BR112014032938A2 (es) |
CA (1) | CA2877056A1 (es) |
MX (2) | MX366405B (es) |
RS (1) | RS60432B1 (es) |
RU (1) | RU2657573C2 (es) |
SI (1) | SI2866825T1 (es) |
WO (1) | WO2014005858A1 (es) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK2651398T3 (en) | 2010-12-16 | 2018-03-12 | Novo Nordisk As | Solid compositions comprising a GLP-1 agonist and a salt of N- (8- (2-hydroxybenzyl) amino) caprylic acid |
CN103619175B (zh) | 2011-04-12 | 2016-08-17 | 诺沃—诺迪斯克有限公司 | 双酰化glp-1衍生物 |
RS57727B1 (sr) | 2012-03-22 | 2018-12-31 | Novo Nordisk As | Kompozicije glp-1 peptida i njihovo dobijanje |
US9993430B2 (en) | 2012-06-20 | 2018-06-12 | Novo Nordisk A/S | Tablet formulation comprising semaglutide and a delivery agent |
MX366405B (es) | 2012-07-01 | 2019-07-08 | Novo Nordisk As | Uso de peptidos glp-1 de accion prolongada. |
CN110254223B (zh) * | 2014-10-16 | 2022-03-25 | 洋马动力科技有限公司 | 拖拉机 |
GB201621987D0 (en) * | 2016-12-22 | 2017-02-08 | Archer Virgil L See Archer Sheri A Arecor Ltd | Novel composition |
DE102017106216A1 (de) * | 2017-03-22 | 2018-09-27 | Amw Gmbh | Extrudierte Depotform zur anhaltenden Wirkstofffreisetzung |
SG11202000940XA (en) | 2017-08-24 | 2020-02-27 | Novo Nordisk As | Glp-1 compositions and uses thereof |
MX2020003049A (es) * | 2017-10-12 | 2020-07-27 | Novo Nordisk As | Semaglutida en la terapia medica. |
GB201720187D0 (en) * | 2017-12-04 | 2018-01-17 | Imperial Innovations Ltd | Novel Compounds |
PE20210453A1 (es) | 2018-02-02 | 2021-03-08 | Novo Nordisk As | Composiciones solidas que comprenden un agonista de glp-1, una sal del acido n-(8-(2-hidroxibenzoil)amino)caprilico y un lubricante |
TWI705820B (zh) | 2018-06-22 | 2020-10-01 | 美商美國禮來大藥廠 | Gip/glp1促效劑組合物 |
WO2020028907A1 (en) * | 2018-08-03 | 2020-02-06 | Brown University | Compositions and methods for improving the bioavailability of glp1 and analogues thereof |
US11492727B2 (en) * | 2019-02-26 | 2022-11-08 | Twist Bioscience Corporation | Variant nucleic acid libraries for GLP1 receptor |
AU2020377469A1 (en) * | 2019-11-06 | 2022-04-28 | Novo Nordisk A/S | GLP-1 receptor agonists in dementia |
KR20220143036A (ko) | 2020-02-18 | 2022-10-24 | 노보 노르디스크 에이/에스 | 약학적 제형 |
CN112768087A (zh) * | 2020-12-23 | 2021-05-07 | 吉林大学 | 利用孟德尔随机化方法验证索马鲁肽口服制剂预防二型糖尿病的用途 |
US20240285729A1 (en) * | 2021-06-24 | 2024-08-29 | Gila Therapeutics, Inc. | Methods and kits for inducing satiety and treating metabolic disorders |
US11865213B2 (en) * | 2021-07-05 | 2024-01-09 | Mapi Pharma Ltd. | Semaglutide depot systems and use thereof |
CN114874314B (zh) * | 2021-12-28 | 2022-11-11 | 北京惠之衡生物科技有限公司 | 一种高表达glp-1类似物的重组工程菌及其构建方法 |
US20230374096A1 (en) * | 2022-05-19 | 2023-11-23 | Vault Bioventures, Inc. | Obesity treatment and prevention methods |
WO2024141760A1 (en) | 2022-12-30 | 2024-07-04 | Algipharma As | Compositions and methods to increase the systemic bioavailability of a polypeptide therapeutic agent undergoing oral administration |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK39892D0 (da) | 1992-03-25 | 1992-03-25 | Bernard Thorens | Peptid |
CA2468374C (en) | 1996-08-30 | 2010-12-21 | Novo-Nordisk A/S | Glp-1 derivatives |
ATE382057T1 (de) * | 2001-06-28 | 2008-01-15 | Novo Nordisk As | Stabile formulierung von modifiziertem glp-1 |
SI2932981T1 (sl) | 2003-09-19 | 2021-11-30 | Novo Nordisk A/S | Albumin-vezavni derivati GLP-1 |
CN104826116A (zh) | 2003-11-20 | 2015-08-12 | 诺沃挪第克公司 | 对于生产和用于注射装置中是最佳的含有丙二醇的肽制剂 |
AU2005303777B2 (en) * | 2004-11-12 | 2010-12-16 | Novo Nordisk A/S | Stable formulations of insulinotropic peptides |
TWI372629B (en) | 2005-03-18 | 2012-09-21 | Novo Nordisk As | Acylated glp-1 compounds |
MX2008013216A (es) * | 2006-04-14 | 2008-10-27 | Mannkind Corp | Formulaciones farmaceuticas de peptido-1 tipo glucagon (glp-1). |
WO2008116088A1 (en) | 2007-03-20 | 2008-09-25 | Nippon Kayaku Kabushiki Kaisha | Method to monitor drug efficacy in diabetic patients using an assay for 1,5-anhydro-d-glucitol |
US20110144010A1 (en) | 2007-06-01 | 2011-06-16 | Novo Nordisk A/S | Spontaneously Dispersible Preconcentrates Including a Peptide Drug in a Solid or Semisolid Carrier |
CN101868476B (zh) | 2007-09-05 | 2015-02-25 | 诺沃-诺迪斯克有限公司 | 胰高血糖素样肽-1衍生物及其制药用途 |
EP2190873B1 (en) | 2007-09-05 | 2015-07-22 | Novo Nordisk A/S | Truncated glp-1 derivatives and their therapeutical use |
US20100317057A1 (en) | 2007-12-28 | 2010-12-16 | Novo Nordisk A/S | Semi-recombinant preparation of glp-1 analogues |
HUE031900T2 (en) | 2008-12-10 | 2017-08-28 | Glaxosmithkline Llc | Pharmaceutical compositions containing Albiglutide |
MX2011008416A (es) * | 2009-02-13 | 2011-09-08 | Boehringer Ingelheim Int | Medicaciones antidiabeticas que comprenden un inhibidor de dpp-4 (linagliptina) opcionalmente en combinacion con otros antidiabeticos. |
DK2513140T3 (en) | 2009-12-16 | 2016-01-18 | Novo Nordisk As | Double-acylated GLP-1 derivatives |
MX341025B (es) * | 2010-05-05 | 2016-08-04 | Boehringer Ingelheim Int Gmbh * | Terapia de combinacion. |
WO2012016419A1 (zh) | 2010-08-06 | 2012-02-09 | 浙江贝达药业有限公司 | Glp-1衍生物及其应用 |
DK2651398T3 (en) | 2010-12-16 | 2018-03-12 | Novo Nordisk As | Solid compositions comprising a GLP-1 agonist and a salt of N- (8- (2-hydroxybenzyl) amino) caprylic acid |
US20130035281A1 (en) | 2011-02-09 | 2013-02-07 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
CN102718858B (zh) | 2011-03-29 | 2014-07-02 | 天津药物研究院 | 胰高血糖素样肽-1类似物单体、二聚体及其制备方法与应用 |
WO2012136790A1 (en) | 2011-04-07 | 2012-10-11 | Glaxo Group Limited | Compositions comprising fusion proteins or conjugates with an improved half -life |
CN102229668A (zh) | 2011-06-03 | 2011-11-02 | 浙江贝达药业有限公司 | 一种glp-1衍生物及其应用 |
WO2012177929A2 (en) * | 2011-06-24 | 2012-12-27 | Amylin Pharmaceuticals, Inc. | Methods for treating diabetes with extended release formulations of glp-1 receptor agonists |
MX366405B (es) | 2012-07-01 | 2019-07-08 | Novo Nordisk As | Uso de peptidos glp-1 de accion prolongada. |
-
2013
- 2013-06-21 MX MX2014014946A patent/MX366405B/es active IP Right Grant
- 2013-06-21 AU AU2013286177A patent/AU2013286177B2/en active Active
- 2013-06-21 EP EP24175788.9A patent/EP4406593A3/en active Pending
- 2013-06-21 JP JP2015519000A patent/JP6059802B2/ja active Active
- 2013-06-21 CA CA2877056A patent/CA2877056A1/en not_active Abandoned
- 2013-06-21 EP EP13737808.9A patent/EP2866825B1/en active Active
- 2013-06-21 EP EP20157813.5A patent/EP3689365A1/en active Pending
- 2013-06-21 BR BR112014032938A patent/BR112014032938A2/pt not_active Application Discontinuation
- 2013-06-21 WO PCT/EP2013/063004 patent/WO2014005858A1/en active Application Filing
- 2013-06-21 RS RS20200684A patent/RS60432B1/sr unknown
- 2013-06-21 RU RU2015101826A patent/RU2657573C2/ru active
- 2013-06-21 US US14/409,493 patent/US9764003B2/en active Active
- 2013-06-21 SI SI201331733T patent/SI2866825T1/sl unknown
-
2014
- 2014-12-05 MX MX2020010693A patent/MX2020010693A/es unknown
-
2017
- 2017-07-21 US US15/656,042 patent/US10335462B2/en active Active
-
2018
- 2018-04-10 AU AU2018202504A patent/AU2018202504B2/en active Active
-
2020
- 2020-04-16 AU AU2020202573A patent/AU2020202573B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
MX2020010693A (es) | 2020-11-06 |
RU2657573C2 (ru) | 2018-06-14 |
SI2866825T1 (sl) | 2020-07-31 |
EP4406593A3 (en) | 2024-10-23 |
JP6059802B2 (ja) | 2017-01-11 |
US20150190474A1 (en) | 2015-07-09 |
JP2015522573A (ja) | 2015-08-06 |
AU2013286177B2 (en) | 2018-04-26 |
RS60432B1 (sr) | 2020-07-31 |
EP2866825B1 (en) | 2020-04-08 |
EP2866825A1 (en) | 2015-05-06 |
AU2018202504A1 (en) | 2018-05-10 |
AU2020202573A1 (en) | 2020-05-07 |
CA2877056A1 (en) | 2014-01-09 |
BR112014032938A2 (pt) | 2017-08-01 |
US9764003B2 (en) | 2017-09-19 |
US20180085435A1 (en) | 2018-03-29 |
AU2020202573B2 (en) | 2023-04-20 |
MX2014014946A (es) | 2015-04-08 |
AU2018202504B2 (en) | 2020-05-07 |
AU2013286177A1 (en) | 2015-01-15 |
US10335462B2 (en) | 2019-07-02 |
WO2014005858A1 (en) | 2014-01-09 |
EP4406593A2 (en) | 2024-07-31 |
EP3689365A1 (en) | 2020-08-05 |
RU2015101826A (ru) | 2016-08-20 |
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Legal Events
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FG | Grant or registration |