MX2018006430A - Preparacion de muestras de acido nucleico. - Google Patents
Preparacion de muestras de acido nucleico.Info
- Publication number
- MX2018006430A MX2018006430A MX2018006430A MX2018006430A MX2018006430A MX 2018006430 A MX2018006430 A MX 2018006430A MX 2018006430 A MX2018006430 A MX 2018006430A MX 2018006430 A MX2018006430 A MX 2018006430A MX 2018006430 A MX2018006430 A MX 2018006430A
- Authority
- MX
- Mexico
- Prior art keywords
- nucleic acid
- sample preparation
- acid sample
- systems
- devices
- Prior art date
Links
- 150000007523 nucleic acids Chemical class 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- 239000012530 fluid Substances 0.000 abstract 2
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 230000007613 environmental effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
Classifications
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- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
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- B01D57/02—Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C by electrophoresis
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C5/00—Separating dispersed particles from liquids by electrostatic effect
- B03C5/005—Dielectrophoresis, i.e. dielectric particles migrating towards the region of highest field strength
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C5/00—Separating dispersed particles from liquids by electrostatic effect
- B03C5/02—Separators
- B03C5/022—Non-uniform field separators
- B03C5/026—Non-uniform field separators using open-gradient differential dielectric separation, i.e. using electrodes of special shapes for non-uniform field creation, e.g. Fluid Integrated Circuit [FIC]
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C7/00—Separating solids from solids by electrostatic effect
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/101—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by chromatography, e.g. electrophoresis, ion-exchange, reverse phase
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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- G—PHYSICS
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- G—PHYSICS
- G01—MEASURING; TESTING
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- G01S5/00—Position-fixing by co-ordinating two or more direction or position line determinations; Position-fixing by co-ordinating two or more distance determinations
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- G01S5/163—Determination of attitude
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
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- G06F3/01—Input arrangements or combined input and output arrangements for interaction between user and computer
- G06F3/03—Arrangements for converting the position or the displacement of a member into a coded form
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
- B01L2400/0424—Dielectrophoretic forces
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/26—Details of magnetic or electrostatic separation for use in medical or biological applications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
- C12Q2565/10—Detection mode being characterised by the assay principle
- C12Q2565/125—Electrophoretic separation
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- G01S11/00—Systems for determining distance or velocity not using reflection or reradiation
- G01S11/12—Systems for determining distance or velocity not using reflection or reradiation using electromagnetic waves other than radio waves
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
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- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Electrochemistry (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Theoretical Computer Science (AREA)
- Clinical Laboratory Science (AREA)
- Pathology (AREA)
- Environmental & Geological Engineering (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Human Computer Interaction (AREA)
- Electromagnetism (AREA)
- Radar, Positioning & Navigation (AREA)
- Remote Sensing (AREA)
- Sustainable Development (AREA)
- Medicinal Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Hematology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
La presente invención incluye métodos, dispositivos y sistemas para aislar un ácido nucleico a partir de un fluido que comprende células. En varios aspectos, los métodos, dispositivos y sistemas pueden permitir un procedimiento rápido que requiere una mínima cantidad de material y/o da como resultado un ácido nucleico de alta pureza aislado a partir de fluidos complejos tales como muestras de sangre o ambientales.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261624897P | 2012-04-16 | 2012-04-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2018006430A true MX2018006430A (es) | 2021-06-15 |
Family
ID=49325450
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014012429A MX356508B (es) | 2012-04-16 | 2013-04-16 | Preparacion de muestras de acido nucleico. |
MX2018006430A MX2018006430A (es) | 2012-04-16 | 2014-10-15 | Preparacion de muestras de acido nucleico. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014012429A MX356508B (es) | 2012-04-16 | 2013-04-16 | Preparacion de muestras de acido nucleico. |
Country Status (11)
Country | Link |
---|---|
US (11) | US8603791B2 (es) |
EP (1) | EP2839035B1 (es) |
JP (3) | JP2015519886A (es) |
KR (1) | KR20150014925A (es) |
CN (1) | CN104583420B (es) |
BR (1) | BR112014025695B1 (es) |
CA (1) | CA2870160C (es) |
ES (1) | ES2856074T3 (es) |
IL (1) | IL235128B (es) |
MX (2) | MX356508B (es) |
WO (1) | WO2013158686A1 (es) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8603791B2 (en) | 2012-04-16 | 2013-12-10 | Biological Dynamics, Inc. | Nucleic acid sample preparation |
US8932815B2 (en) | 2012-04-16 | 2015-01-13 | Biological Dynamics, Inc. | Nucleic acid sample preparation |
US10323279B2 (en) | 2012-08-14 | 2019-06-18 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
US9701998B2 (en) | 2012-12-14 | 2017-07-11 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
US9951386B2 (en) | 2014-06-26 | 2018-04-24 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
US11591637B2 (en) | 2012-08-14 | 2023-02-28 | 10X Genomics, Inc. | Compositions and methods for sample processing |
EP2885418A4 (en) | 2012-08-14 | 2016-03-02 | 10X Genomics Inc | MICROCAPSE COMPOSITIONS AND METHOD THEREFOR |
US10400280B2 (en) | 2012-08-14 | 2019-09-03 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
US10752949B2 (en) | 2012-08-14 | 2020-08-25 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
AU2013359165B2 (en) | 2012-12-14 | 2019-09-12 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
US10533221B2 (en) | 2012-12-14 | 2020-01-14 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
CN105102697A (zh) | 2013-02-08 | 2015-11-25 | 10X基因组学有限公司 | 多核苷酸条形码生成 |
EP3049531B8 (en) * | 2013-09-24 | 2019-08-14 | AIT Austrian Institute of Technology GmbH | Method for pathogen diagnosis using an electric field |
KR20160144428A (ko) | 2014-04-08 | 2016-12-16 | 바이오로지컬 다이나믹스, 인크. | 생물학적 물질 분리를 위한 개선된 장치 |
CN106413896B (zh) | 2014-04-10 | 2019-07-05 | 10X基因组学有限公司 | 用于封装和分割试剂的流体装置、系统和方法及其应用 |
EP3158088A4 (en) * | 2014-06-20 | 2017-12-27 | Biological Dynamics, Inc. | Nucleic acid sample preparation |
CN106795553B (zh) | 2014-06-26 | 2021-06-04 | 10X基因组学有限公司 | 分析来自单个细胞或细胞群体的核酸的方法 |
CN106575754A (zh) * | 2014-12-02 | 2017-04-19 | 株式会社东芝 | 负极活性物质、非水电解质电池及电池包 |
EP3237899A4 (en) * | 2014-12-24 | 2018-09-26 | Fluid-Screen, Inc. | Apparatus for pathogen detection |
CN112126675B (zh) | 2015-01-12 | 2022-09-09 | 10X基因组学有限公司 | 用于制备核酸测序文库的方法和系统以及用其制备的文库 |
KR101735083B1 (ko) * | 2015-02-05 | 2017-05-25 | 주식회사 씨디젠 | Dna 추출 디스크 장치 및 이를 이용한 dna 추출 방법 |
US10697000B2 (en) | 2015-02-24 | 2020-06-30 | 10X Genomics, Inc. | Partition processing methods and systems |
US20160327549A1 (en) | 2015-05-04 | 2016-11-10 | Biological Dynamics, Inc. | Particle based immunoassay with alternating current electrokinetics |
US10379101B2 (en) | 2015-11-23 | 2019-08-13 | Hai Kang Life Corporation Limited | Apparatus for detection of biomolecules and its fabrication |
EP4144861B1 (en) * | 2015-12-04 | 2024-09-11 | 10X Genomics, Inc. | Methods and compositions for nucleic acid analysis |
CN105505772B (zh) * | 2015-12-07 | 2018-07-10 | 中国科学院苏州生物医学工程技术研究所 | 对单个外泌体进行裂解的装置 |
CN105647799B (zh) * | 2016-02-24 | 2018-08-10 | 西安交通大学 | 一种组合式场流分离的循环肿瘤细胞分离装置 |
AU2017237187B2 (en) | 2016-03-24 | 2022-12-08 | Biological Dynamics, Inc. | Disposable fluidic cartridge and components |
US10815525B2 (en) | 2016-12-22 | 2020-10-27 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
US10550429B2 (en) | 2016-12-22 | 2020-02-04 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
EP4310183A3 (en) | 2017-01-30 | 2024-02-21 | 10X Genomics, Inc. | Methods and systems for droplet-based single cell barcoding |
WO2018208820A1 (en) | 2017-05-08 | 2018-11-15 | Biological Dynamics, Inc. | Methods and systems for analyte information processing |
US10844372B2 (en) | 2017-05-26 | 2020-11-24 | 10X Genomics, Inc. | Single cell analysis of transposase accessible chromatin |
EP3445876B1 (en) | 2017-05-26 | 2023-07-05 | 10X Genomics, Inc. | Single cell analysis of transposase accessible chromatin |
EP3625361A1 (en) | 2017-11-15 | 2020-03-25 | 10X Genomics, Inc. | Functionalized gel beads |
US10829815B2 (en) | 2017-11-17 | 2020-11-10 | 10X Genomics, Inc. | Methods and systems for associating physical and genetic properties of biological particles |
JP2021509265A (ja) * | 2017-12-19 | 2021-03-25 | バイオロジカル ダイナミクス,インク. | 生体サンプルからの複数の分析物の検出のための方法およびデバイス |
EP3728582A4 (en) * | 2017-12-19 | 2021-09-01 | Biological Dynamics, Inc. | METHODS AND DEVICES FOR DETECTION AND QUANTIFICATION OF ACELLULAR DNA FRAGMENTS |
IL271026B2 (en) | 2017-12-21 | 2024-11-01 | Illumina Inc | Flow cells with hydrogel coating |
JP2021520218A (ja) | 2018-04-02 | 2021-08-19 | バイオロジカル ダイナミクス,インク. | 誘電体材料 |
EP3775271A1 (en) | 2018-04-06 | 2021-02-17 | 10X Genomics, Inc. | Systems and methods for quality control in single cell processing |
TWI725686B (zh) | 2018-12-26 | 2021-04-21 | 財團法人工業技術研究院 | 用於產生液珠的管狀結構及液珠產生方法 |
NL2023366B1 (en) * | 2019-02-08 | 2020-08-19 | Illumina Inc | Methods and devices for mixing in a microfluidic system |
KR20230054790A (ko) * | 2019-07-16 | 2023-04-25 | 멜리오랩스 인코포레이티드 | 단일-세포 기반 디지털 고해상도 용융을 위한 방법 및 장치 |
WO2021222084A1 (en) | 2020-04-28 | 2021-11-04 | Siemens Healthcare Diagnostics Inc. | Acoustophoretic lysis devices and methods |
CN112011446A (zh) * | 2020-08-31 | 2020-12-01 | 吉林大学 | 一种用于细菌裂解的微流控芯片、细菌裂解装置及其应用 |
EP4278174A1 (en) * | 2021-01-12 | 2023-11-22 | Biological Dynamics, Inc. | Methods and systems for detection and discovery of biomarkers |
CN113801964A (zh) * | 2021-10-13 | 2021-12-17 | 四川大学 | 一种病毒rna的无探针检测方法 |
Family Cites Families (59)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6149789A (en) | 1990-10-31 | 2000-11-21 | Fraunhofer Gesellschaft Zur Forderung Der Angewandten Forschung E.V. | Process for manipulating microscopic, dielectric particles and a device therefor |
US5632957A (en) | 1993-11-01 | 1997-05-27 | Nanogen | Molecular biological diagnostic systems including electrodes |
US5856097A (en) | 1992-03-04 | 1999-01-05 | The Regents Of The University Of California | Comparative genomic hybridization (CGH) |
US6403367B1 (en) | 1994-07-07 | 2002-06-11 | Nanogen, Inc. | Integrated portable biological detection system |
US6071394A (en) | 1996-09-06 | 2000-06-06 | Nanogen, Inc. | Channel-less separation of bioparticles on a bioelectronic chip by dielectrophoresis |
US6641708B1 (en) | 1996-01-31 | 2003-11-04 | Board Of Regents, The University Of Texas System | Method and apparatus for fractionation using conventional dielectrophoresis and field flow fractionation |
GB9615775D0 (en) | 1996-07-26 | 1996-09-04 | British Tech Group | Apparatus and method for characterising particles using dielectrophoresis |
GB2319067B (en) | 1996-11-06 | 2000-06-28 | T & N Technology Ltd | Forming a bearing |
EP1089824B1 (de) | 1998-06-26 | 2003-11-05 | Evotec OAI AG | Elektrodenanordnung zur dielektrophoretischen partikelablenkung |
US6203683B1 (en) * | 1998-11-09 | 2001-03-20 | Princeton University | Electrodynamically focused thermal cycling device |
US6294063B1 (en) | 1999-02-12 | 2001-09-25 | Board Of Regents, The University Of Texas System | Method and apparatus for programmable fluidic processing |
CN1181337C (zh) | 2000-08-08 | 2004-12-22 | 清华大学 | 微流体系统中实体分子的操纵方法及相关试剂盒 |
AU6494300A (en) | 1999-08-17 | 2001-03-13 | Porex Technologies Corporation | Self-sealing materials and devices comprising same |
US6824664B1 (en) | 1999-11-04 | 2004-11-30 | Princeton University | Electrode-less dielectrophorises for polarizable particles |
JP2004532968A (ja) | 2000-06-14 | 2004-10-28 | ボード・オブ・リージェンツ,ザ・ユニヴァーシティ・オヴ・テキサス・システム | 細胞亜集団分析のためのシステムおよび方法 |
CN100392384C (zh) | 2000-10-09 | 2008-06-04 | 清华大学 | 芯片上分离实体分子的方法和样品溶液 |
US6880576B2 (en) | 2001-06-07 | 2005-04-19 | Nanostream, Inc. | Microfluidic devices for methods development |
US7081189B2 (en) | 2001-12-18 | 2006-07-25 | Massachusetts Institute Of Technology | Microfluidic pumps and mixers driven by induced-charge electro-osmosis |
US6887362B2 (en) * | 2002-02-06 | 2005-05-03 | Nanogen, Inc. | Dielectrophoretic separation and immunoassay methods on active electronic matrix devices |
GB2392977A (en) | 2002-09-13 | 2004-03-17 | Suisse Electronique Microtech | A fluidic dielectrophoretic system and method for analysing biomolecules |
CA2511331A1 (en) | 2002-12-20 | 2004-07-15 | Board Of Regents, The University Of Texas System | Methods and apparatus for electrosmear analysis |
DE10311716A1 (de) | 2003-03-17 | 2004-10-14 | Evotec Oai Ag | Verfahren und Vorrichtung zur Trennung von Partikeln in einer Flüssigkeitsströmung |
AU2004262301A1 (en) | 2003-07-25 | 2005-02-10 | Platypus Technologies, Llc | Liquid crystal based analyte detection |
US8256246B2 (en) | 2003-10-29 | 2012-09-04 | Miele & Cie. Kg. | Aggregate for a washing machine with a plastic sudsing container |
CA2556981C (en) | 2004-02-18 | 2015-10-13 | The Trustees Of Boston University | Method for detecting and quantifying rare mutations or polymorphisms |
US20070240495A1 (en) | 2004-05-25 | 2007-10-18 | Shuzo Hirahara | Microfluidic Device and Analyzing/Sorting Apparatus Using The Same |
JP2006047153A (ja) | 2004-08-05 | 2006-02-16 | Sony Corp | Dnaチップの製造方法と製造システム、ハイブリダイゼーション検出方法と検出システム、並びに基板処理装置と基板処理方法 |
JP4645110B2 (ja) * | 2004-09-15 | 2011-03-09 | ソニー株式会社 | 誘電泳動を利用するハイブリダイゼーション検出部と該検出部を備えるセンサーチップ、並びにハイブリダイゼーション検出方法 |
US7047832B1 (en) | 2004-11-08 | 2006-05-23 | Oporgenics, Inc., Llc | Apparatus for measuring gas exchange |
EP1764418B1 (en) | 2005-09-14 | 2012-08-22 | STMicroelectronics Srl | Method and device for the treatment of biological samples using dielectrophoresis |
US20070080062A1 (en) | 2005-10-03 | 2007-04-12 | Harnett Cindy K | Coated metal structures and methods of making and using thereof |
WO2007102839A2 (en) | 2005-10-27 | 2007-09-13 | Applera Corporation | Optoelectronic separation of biomolecules |
TWI304752B (en) | 2005-12-09 | 2009-01-01 | Ind Tech Res Inst | Multi-sample microfluidic dielectrophoresis separator |
KR100745754B1 (ko) | 2005-12-29 | 2007-08-02 | 삼성전자주식회사 | 금속 기둥 전극 구조를 포함하는 유전 영동을 이용하여입자를 조작하기 위한 장치 및 그를 이용하여 빠른유속으로 유전 영동에 의하여 입자를 조작할 수 있는 방법 |
DE102006002462A1 (de) | 2006-01-18 | 2007-07-19 | Evotec Technologies Gmbh | Elektrischer Feldkäfig und zugehöriges Betriebsverfahren |
JP2009530634A (ja) | 2006-03-21 | 2009-08-27 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | フィールド電極群を備えたマイクロエレクトロニクスデバイス |
US20090314644A1 (en) | 2006-04-10 | 2009-12-24 | Technion Research & Development Foundation Ltd. | Method and Device for Electrokinetic Manipulation |
KR100813254B1 (ko) | 2006-05-29 | 2008-03-13 | 삼성전자주식회사 | 유전 영동을 통하여 분극성 분석물을 분리하기 위한 장치및 그를 이용하여 시료 중의 분극성 물질을 분리하는 방법 |
JP2008298575A (ja) | 2007-05-31 | 2008-12-11 | Panasonic Corp | 電極および製造方法とそれを用いた検出装置と検出方法 |
DE102007037013A1 (de) | 2007-08-06 | 2009-02-19 | Clariant International Ltd. | Biozide Zusammensetzungen |
BRPI0910898B1 (pt) | 2008-04-03 | 2021-09-14 | The Regents Of The University Of California | Dispositivo eletrocinético de corrente alternada para isolar analitos em nano escala a partir de amostras de alta condutividade em uma região de alto campo dieletroforético (dep), método para separar analitos em nano escala a partir de grandes entidades em uma amostra de alta condutância e sistema para separação de material biológico |
EP2253352A1 (en) | 2009-05-21 | 2010-11-24 | Debiotech S.A. | Passive fluid flow regulator |
JP5306092B2 (ja) | 2009-07-17 | 2013-10-02 | キヤノン株式会社 | 流体制御装置 |
DE102009028493B4 (de) | 2009-08-13 | 2023-08-24 | Robert Bosch Gmbh | Mikrofluidische Zelle |
WO2011057347A1 (en) | 2009-11-12 | 2011-05-19 | Tgr Biosciences Pty Ltd | Analyte detection |
GB201102385D0 (en) | 2011-02-10 | 2011-03-30 | Biocule Scotland Ltd | Two-dimensional gel electrophoresis apparatus and method |
CN102320559B (zh) | 2011-09-14 | 2014-06-18 | 上海交通大学 | 一种中空结构的微阵列电极的制备方法 |
WO2013086486A1 (en) | 2011-12-09 | 2013-06-13 | President And Fellows Of Harvard College | Integrated human organ-on-chip microphysiological systems |
EP2834622B1 (en) | 2012-04-03 | 2023-04-12 | Illumina, Inc. | Integrated optoelectronic read head and fluidic cartridge useful for nucleic acid sequencing |
US8932815B2 (en) | 2012-04-16 | 2015-01-13 | Biological Dynamics, Inc. | Nucleic acid sample preparation |
US8603791B2 (en) | 2012-04-16 | 2013-12-10 | Biological Dynamics, Inc. | Nucleic acid sample preparation |
WO2014015187A1 (en) | 2012-07-18 | 2014-01-23 | Biological Dynamics, Inc. | Manipulation of microparticles in low field dielectrophoretic regions |
WO2014028222A1 (en) | 2012-07-31 | 2014-02-20 | Crown Bioscience, Inc. | Biomarkers for identifying esophageal cancer patients for treatment with an anti-egfr drug |
US9551665B2 (en) | 2012-10-01 | 2017-01-24 | National Cheng Kung University | Method for detecting mitochondria gene alterations |
WO2015038797A1 (en) | 2013-09-13 | 2015-03-19 | The Board Of Trustees Of The Leland Stanford Junior University | Plasmonic beads for multiplexed analysis by flow detection systems |
KR20160144428A (ko) | 2014-04-08 | 2016-12-16 | 바이오로지컬 다이나믹스, 인크. | 생물학적 물질 분리를 위한 개선된 장치 |
EP3158088A4 (en) | 2014-06-20 | 2017-12-27 | Biological Dynamics, Inc. | Nucleic acid sample preparation |
US20160327549A1 (en) | 2015-05-04 | 2016-11-10 | Biological Dynamics, Inc. | Particle based immunoassay with alternating current electrokinetics |
AU2017237187B2 (en) | 2016-03-24 | 2022-12-08 | Biological Dynamics, Inc. | Disposable fluidic cartridge and components |
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