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MX2017010506A - Nuevo derivado de quinoleina para usarse en el tratamiento y prevencion de infecciones virales. - Google Patents

Nuevo derivado de quinoleina para usarse en el tratamiento y prevencion de infecciones virales.

Info

Publication number
MX2017010506A
MX2017010506A MX2017010506A MX2017010506A MX2017010506A MX 2017010506 A MX2017010506 A MX 2017010506A MX 2017010506 A MX2017010506 A MX 2017010506A MX 2017010506 A MX2017010506 A MX 2017010506A MX 2017010506 A MX2017010506 A MX 2017010506A
Authority
MX
Mexico
Prior art keywords
quinoline derivative
prevention
treatment
viral infections
present
Prior art date
Application number
MX2017010506A
Other languages
English (en)
Inventor
Najman Romain
Tazi Jamal
Scherrer Didier
Garcel Aude
Campos Noëlie
VAUTRIN Audrey
Mahuteau Florence
FORNARELLI Pauline
Original Assignee
Abivax
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abivax filed Critical Abivax
Publication of MX2017010506A publication Critical patent/MX2017010506A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a un derivado de quinoleína de la fórmula (1) o una de sus sales farmacéuticamente aceptables. La presente invención se refiere además al derivado de quinoleína para el medicamento y para su uso en el tratamiento o prevención de una infección viral o retroviral y en particular el SIDA o una afección relacionada con el SIDA o el virus de inmunodeficiencia humana (VIH). La presente invención se refiere también a una composición farmacéutica que comprende el derivado de quinoleína y al proceso para prepararla como un nuevo compuesto intermedio.
MX2017010506A 2015-02-23 2016-02-19 Nuevo derivado de quinoleina para usarse en el tratamiento y prevencion de infecciones virales. MX2017010506A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15305274.1A EP3059236A1 (en) 2015-02-23 2015-02-23 A new quinoline derivative for use in the treatment and prevention of viral infections
PCT/EP2016/053532 WO2016135052A1 (en) 2015-02-23 2016-02-19 A new quinoline derivative for use in the treatment and prevention of viral infections

Publications (1)

Publication Number Publication Date
MX2017010506A true MX2017010506A (es) 2017-11-13

Family

ID=52629497

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017010506A MX2017010506A (es) 2015-02-23 2016-02-19 Nuevo derivado de quinoleina para usarse en el tratamiento y prevencion de infecciones virales.

Country Status (22)

Country Link
US (1) US10329317B2 (es)
EP (2) EP3059236A1 (es)
JP (1) JP6797126B2 (es)
KR (1) KR102583506B1 (es)
CN (1) CN107531681B (es)
AU (1) AU2016223687B2 (es)
BR (1) BR112017017500B1 (es)
CA (1) CA2975577C (es)
CU (1) CU24525B1 (es)
DK (1) DK3262037T3 (es)
ES (1) ES2785374T3 (es)
HR (1) HRP20200649T1 (es)
HU (1) HUE048577T2 (es)
LT (1) LT3262037T (es)
MX (1) MX2017010506A (es)
PL (1) PL3262037T3 (es)
PT (1) PT3262037T (es)
RS (1) RS60369B1 (es)
RU (1) RU2723013C2 (es)
SI (1) SI3262037T1 (es)
WO (1) WO2016135052A1 (es)
ZA (1) ZA201705633B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2757161A1 (en) 2013-01-17 2014-07-23 Splicos miRNA-124 as a biomarker of viral infection
EP2974729A1 (en) 2014-07-17 2016-01-20 Abivax Quinoline derivatives for use in the treatment of inflammatory diseases
EP3059591A1 (en) 2015-02-23 2016-08-24 Abivax Methods for screening compounds for treating or preventing a viral infection or a virus-related condition
US20190034990A1 (en) * 2017-07-26 2019-01-31 International Business Machines Corporation Information insight system for providers of products or services
EP3669873A1 (en) 2018-12-20 2020-06-24 Abivax Quinoline derivatives for use ine the traeatment of inflammation diseases
EP3669874A1 (en) * 2018-12-20 2020-06-24 Abivax Quinoline derivatives for use in the treatment or prevention of cancer
EP3884946A1 (en) * 2020-03-25 2021-09-29 Abivax Compounds for treating or preventing a coronaviridae infection & methods and uses for assessing the occurrence of a coronaviridae infection
EP3881844A1 (en) * 2020-03-20 2021-09-22 Abivax Compounds for treating or preventing a coronaviridae infection & methods and uses for assessing the occurrence of a coronaviridae infection
AU2021238792A1 (en) * 2020-03-20 2022-10-13 Abivax Compounds for treating or preventing a Coronaviridae infection and methods and uses for assessing the occurrence of a Coronaviridae infection
MX2023013972A (es) * 2021-05-27 2023-12-11 Jiangsu Hengrui Pharmaceuticals Co Ltd Compuesto de quinolinamina, metodo de preparacion y aplicacion del mismo en productos farmaceuticos.
EP4201948A1 (en) 2021-12-21 2023-06-28 Abivax Method of preparation of 1-(n-(quinolin-2-yl)-(phenylamino)-1-deoxy-beta-d-glucopyranuronic acid derivatives
EP4212156A1 (en) 2022-01-13 2023-07-19 Abivax Combination of 8-chloro-n-(4-(trifluoromethoxy)phenyl)quinolin-2-amine and its derivatives with a s1p receptor modulator
EP4215196A1 (en) * 2022-01-24 2023-07-26 Abivax Combination of 8-chloro-n-(4-(trifluoromethoxy)phenyl)quinolin-2-amine and its derivatives with a jak inhibitor
WO2024109936A1 (zh) * 2022-11-25 2024-05-30 江苏恒瑞医药股份有限公司 一种喹啉胺类化合物晶型及其制备方法
WO2024109937A1 (zh) * 2022-11-25 2024-05-30 江苏恒瑞医药股份有限公司 一种喹啉胺类化合物的可药用盐、晶型及其制备方法
CN116617226B (zh) * 2023-06-21 2024-06-25 湖北工业大学 新型吲哚喹啉衍生物作为肠道病毒71型抑制剂的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2436786A1 (fr) 1978-09-21 1980-04-18 Anvar Nouveaux derives des pyrido (4,3-b) carbazoles (ellipticines), substitues en position 1 par une chaine polyaminee, leur obtention et leur application a titre de medicaments
FR2627493B1 (fr) 1988-02-23 1991-10-31 Sanofi Sa Procede de preparation de derives d'isoquinoleine
FR2645861A1 (fr) 1989-04-17 1990-10-19 Inst Nat Sante Rech Med Utilisation de dipyrido (4,3-b) (3,4-f) indoles pour la preparation de medicaments utiles pour le traitement du sida
US5354853A (en) * 1993-03-12 1994-10-11 Genzyme Corporation Phospholipid-saccharide conjugates
FR2859474B1 (fr) 2003-09-04 2006-01-13 Centre Nat Rech Scient Utilisation de composes derives d'indole pour la preparation d'un medicament utile pour le traitement de maladies genetiques resultant de l'alteration des processus d'epissage
HRP20230248T1 (hr) * 2009-06-12 2023-04-14 Abivax Spojevi korisni za liječenje preranog starenja, te naročito progerije
EP2465502A1 (en) 2010-12-15 2012-06-20 Société Splicos Compounds useful for treating AIDS
MX2015017599A (es) * 2013-07-05 2016-04-07 Abivax Compuestos biciclicos utiles para el tratamiento de enfermedades causadas por retrovirus.
EP2975034A1 (en) 2014-07-17 2016-01-20 Abivax A quinoline derivative for the treatment of inflammatory diseases and AIDS
EP2974729A1 (en) 2014-07-17 2016-01-20 Abivax Quinoline derivatives for use in the treatment of inflammatory diseases

Also Published As

Publication number Publication date
RU2017128643A (ru) 2019-03-25
EP3262037B1 (en) 2020-02-12
SI3262037T1 (sl) 2020-09-30
ES2785374T3 (es) 2020-10-06
EP3262037A1 (en) 2018-01-03
US10329317B2 (en) 2019-06-25
WO2016135052A1 (en) 2016-09-01
BR112017017500B1 (pt) 2023-04-04
CU20170109A7 (es) 2018-02-08
KR20170129698A (ko) 2017-11-27
HUE048577T2 (hu) 2020-07-28
PT3262037T (pt) 2020-04-09
BR112017017500A2 (pt) 2018-04-17
US20180030078A1 (en) 2018-02-01
AU2016223687A1 (en) 2017-08-31
KR102583506B1 (ko) 2023-09-26
HRP20200649T1 (hr) 2020-10-16
CN107531681B (zh) 2020-11-24
RU2017128643A3 (es) 2019-04-15
EP3059236A1 (en) 2016-08-24
JP6797126B2 (ja) 2020-12-09
CA2975577C (en) 2020-04-07
CU24525B1 (es) 2021-06-08
JP2018507215A (ja) 2018-03-15
PL3262037T3 (pl) 2020-10-19
RS60369B1 (sr) 2020-07-31
CA2975577A1 (en) 2016-09-01
LT3262037T (lt) 2020-07-10
AU2016223687B2 (en) 2020-03-19
RU2723013C2 (ru) 2020-06-08
ZA201705633B (en) 2018-12-19
CN107531681A (zh) 2018-01-02
DK3262037T3 (da) 2020-05-04

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