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MX2016005993A - Anfifilos biscationicos y triscationicos como agentes antimicrobianos. - Google Patents

Anfifilos biscationicos y triscationicos como agentes antimicrobianos.

Info

Publication number
MX2016005993A
MX2016005993A MX2016005993A MX2016005993A MX2016005993A MX 2016005993 A MX2016005993 A MX 2016005993A MX 2016005993 A MX2016005993 A MX 2016005993A MX 2016005993 A MX2016005993 A MX 2016005993A MX 2016005993 A MX2016005993 A MX 2016005993A
Authority
MX
Mexico
Prior art keywords
triscationic
biscationic
compound
amphiles
antimicrobial agents
Prior art date
Application number
MX2016005993A
Other languages
English (en)
Inventor
WUEST William
Patrick Minbiole Kevin
Original Assignee
Univ Temple
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Temple filed Critical Univ Temple
Publication of MX2016005993A publication Critical patent/MX2016005993A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02—Amines; Quaternary ammonium compounds
    • A01N33/12—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/132—Amines having two or more amino groups, e.g. spermidine, putrescine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Plant Pathology (AREA)
  • Zoology (AREA)
  • Pest Control & Pesticides (AREA)
  • Environmental Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente divulgación proporciona una composición antimicrobiana que incluye un compuesto que es un anfífilo biscatiónico o triscatiónico, y el método para elaborar tal composición antimicrobiana y el método para usar tal compuesto o composición para el uso antimicrobiano. La composición antimicrobiana puede incluir un compuesto que tiene la fórmula (I) donde R es un grupo metileno no sustituido u opcionalmente sustituido, s es un número entero en el intervalo de 1 a 6, R1, R2, R3 o R4 es H o un alquilo de 1 a 4 átomos de carbono no sustituido u opcionalmente sustituido, X es un halógeno, m y n son números enteros en el intervalo de 5 a 25, y m no es igual a n. Alternativamente, la composición antimicrobiana puede comprender un compuesto que tiene la fórmula (III) o (IV) donde R1, R2, R3, R4 R5, o R6 es H o un alquilo de 1 a 4 átomos de carbono no sustituido u opcionalmente sustituido, X o Y es un halógeno y m y n son números enteros en el intervalo de 5 a 25.
MX2016005993A 2013-11-05 2014-11-05 Anfifilos biscationicos y triscationicos como agentes antimicrobianos. MX2016005993A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361900037P 2013-11-05 2013-11-05
PCT/US2014/064114 WO2015069760A1 (en) 2013-11-05 2014-11-05 Biscationic and triscationic amphiles as antimicrobial agents

Publications (1)

Publication Number Publication Date
MX2016005993A true MX2016005993A (es) 2017-01-11

Family

ID=53042030

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016005993A MX2016005993A (es) 2013-11-05 2014-11-05 Anfifilos biscationicos y triscationicos como agentes antimicrobianos.

Country Status (8)

Country Link
US (1) US20160278375A1 (es)
EP (1) EP3065547A4 (es)
JP (1) JP2016535785A (es)
CN (1) CN106061252A (es)
AU (1) AU2014346842A1 (es)
CA (1) CA2929559A1 (es)
MX (1) MX2016005993A (es)
WO (1) WO2015069760A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2684150C (en) 2007-05-14 2016-10-04 Research Foundation Of State University Of New York Decenoic acid dispersion inducers in the treatment of biofilms
WO2015069764A1 (en) * 2013-11-05 2015-05-14 Temple University Of The Commonwealth System Of Higher Education Polycationic amphiphiles as antimicrobial agents
US10398142B2 (en) 2013-11-05 2019-09-03 Temple University Of The Commonwealth System Of Higher Education Polycationic amphiphiles as antimicrobial agents
US10301254B2 (en) 2015-04-23 2019-05-28 Temple University—Of the Commonwealth System of Higher Education Substituted polycationic multi-quaternary ammonium salts as antimicrobial agents
CN106674017B (zh) * 2015-11-06 2018-12-28 中国石油化工股份有限公司 一种不对称双季铵盐的合成方法及其应用
CN106674018B (zh) * 2015-11-06 2018-12-28 中国石油化工股份有限公司 一种合成不对称双季铵盐的方法及其应用
US11111216B2 (en) 2016-10-26 2021-09-07 Temple University-Of The Commonwealth System Of Higher Education Polycationic amphiphiles as antimicrobial agents and methods using same
WO2019217854A1 (en) * 2018-05-11 2019-11-14 Wisconsin Alumni Research Foundation An ionic liquid-based nanoemulsion formulation for the efficient delivery of hydrophilic and hydrophobic therapeutic agents
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
CN114105776B (zh) * 2021-11-23 2023-06-27 中国石油大学(北京) 一种合成不对称双季铵盐的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1577286A (es) * 1968-01-31 1969-08-08
US3719711A (en) * 1970-10-19 1973-03-06 Procter & Gamble Oligomeric quaternary ammonium antibacterial agents
CS229093B1 (cs) * 1983-01-03 1984-05-14 Devinsky Ferdinand N,N"-bis(alkyldimetyl)-3-aza-3-metyl-1,5-pentándiamóniumdibroniidy a spósob ich přípravy
US7385012B2 (en) * 2003-11-03 2008-06-10 Ilypsa, Inc. Polyamine polymers
US20060025458A1 (en) * 2004-07-30 2006-02-02 University Of Connecticut Alkylammonium compounds as antifungal and antitrypanosomal agents
EP2325278B1 (en) * 2005-11-07 2015-09-09 Stepan Company Polycationic viscoelastic compositions
CN102060715A (zh) * 2010-12-22 2011-05-18 南京大学 双季铵羧酸盐功能化离子液体及其制法

Also Published As

Publication number Publication date
JP2016535785A (ja) 2016-11-17
AU2014346842A1 (en) 2016-06-09
CA2929559A1 (en) 2015-05-14
EP3065547A4 (en) 2017-08-16
US20160278375A1 (en) 2016-09-29
CN106061252A (zh) 2016-10-26
WO2015069760A1 (en) 2015-05-14
EP3065547A1 (en) 2016-09-14

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