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MX2011005604A - Vacuna recombinante para influenza aviar y sus usos. - Google Patents

Vacuna recombinante para influenza aviar y sus usos.

Info

Publication number
MX2011005604A
MX2011005604A MX2011005604A MX2011005604A MX2011005604A MX 2011005604 A MX2011005604 A MX 2011005604A MX 2011005604 A MX2011005604 A MX 2011005604A MX 2011005604 A MX2011005604 A MX 2011005604A MX 2011005604 A MX2011005604 A MX 2011005604A
Authority
MX
Mexico
Prior art keywords
influenza
encompasses
vaccines
avian influenza
influenza vaccine
Prior art date
Application number
MX2011005604A
Other languages
English (en)
Inventor
Lynn F Dickey
Xuan Guo
Michel Bublot
Joyce A Pritchard
Original Assignee
Merial Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42044426&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2011005604(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merial Ltd filed Critical Merial Ltd
Publication of MX2011005604A publication Critical patent/MX2011005604A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/517Plant cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente invención abarca vacunas para influenza, en particular vacunas para influenza aviar. La vacuna puede ser una vacuna subunitaria basada en la hemaglutinina de influenza. La hemaglutinina puede ser expresada en plantas incluyendo la lenteja de agua. La invención también abarca vectores recombinantes que codifican y que expresan antígenos, epítopes o inmunógenos de influenza que se pueden utilizar para proteger a los animales contra la influenza. También abarca un régimen de vacunación compatible con la estrategia DIVA, incluyendo un esquema de inicio-esfuerzo utilizando el vector y vacunas subunitarias.
MX2011005604A 2008-11-28 2009-11-30 Vacuna recombinante para influenza aviar y sus usos. MX2011005604A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11849208P 2008-11-28 2008-11-28
PCT/US2009/066146 WO2010063033A2 (en) 2008-11-28 2009-11-30 Recombinant avian influenza vaccine and uses thereof

Publications (1)

Publication Number Publication Date
MX2011005604A true MX2011005604A (es) 2011-09-01

Family

ID=42044426

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011005604A MX2011005604A (es) 2008-11-28 2009-11-30 Vacuna recombinante para influenza aviar y sus usos.

Country Status (11)

Country Link
US (1) US8394384B2 (es)
EP (3) EP3168307B1 (es)
KR (1) KR101715415B1 (es)
CN (1) CN102271704A (es)
CA (1) CA2744454C (es)
GT (1) GT201100145A (es)
IL (1) IL213189A (es)
MX (1) MX2011005604A (es)
MY (1) MY159543A (es)
RU (1) RU2559527C2 (es)
WO (1) WO2010063033A2 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2011005604A (es) 2008-11-28 2011-09-01 Merial Ltd Vacuna recombinante para influenza aviar y sus usos.
AR079767A1 (es) 2009-12-28 2012-02-15 Merial Ltd Antigeno ndv (virus de la enfermedad de newcastle) recombinante y usos del mismo
US20110236416A1 (en) * 2010-03-12 2011-09-29 Jean-Christophe Audonnet Foot and mouth disease virus recombinant vaccines and uses thereof
ES2635019T3 (es) * 2010-10-18 2017-10-02 Intervet International B.V. Vacuna con vector del herpesvirus de pavo contra la gripe aviar en aves de corral
CN103357004B (zh) * 2013-07-23 2014-10-01 武汉中博生物股份有限公司 一种提高禽流感抗原利用率的方法
WO2015048129A1 (en) * 2013-09-24 2015-04-02 CHOI, Duk, Kyung Avian influenza virus polypeptides and methods of their use
MX2017005687A (es) 2014-11-03 2017-08-21 Merial Inc Metodos para usar formulaciones para vacuna con microagujas para elicitar en animales inmunidad protectora contra virus de la rabia.
CN107847579A (zh) * 2014-12-19 2018-03-27 俄勒冈健康与科学大学 人和禽h5n1流感的计算优化的广泛反应性抗原的协同共同给药
JOP20190088A1 (ar) 2016-10-21 2019-04-21 Us Agriculture نواقل مؤتلفة للتعبير عن مولدات مضاد فيروس انفلونزا الطيور و استخداماتها
US11529413B2 (en) 2018-06-12 2022-12-20 Kbio Holdings Limited Virus and antigen purification and conjugation
JP7315590B2 (ja) 2018-06-12 2023-07-26 クビオ・ホールディングス・リミテッド ウイルスと抗原の精製及び結合
US11696948B2 (en) 2018-06-12 2023-07-11 Kbio Holdings Limited Vaccines formed by virus and antigen conjugation
US11690907B2 (en) 2018-06-12 2023-07-04 Kbio Holdings Limited Vaccines formed by virus and antigen conjugation
CN112708599B (zh) * 2019-10-25 2022-02-18 中国农业大学 一株禽流感病毒疫苗株及其应用
CN113913395B (zh) * 2021-10-19 2022-06-14 中国农业科学院哈尔滨兽医研究所(中国动物卫生与流行病学中心哈尔滨分中心) 人工重组的h5n8流感病毒及其制备方法和应用

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Also Published As

Publication number Publication date
EP3542815A1 (en) 2019-09-25
EP2367566A2 (en) 2011-09-28
CA2744454C (en) 2020-03-24
KR101715415B1 (ko) 2017-03-10
RU2011126359A (ru) 2013-01-10
EP3168307A1 (en) 2017-05-17
WO2010063033A3 (en) 2010-10-28
MY159543A (en) 2017-01-13
KR20110108337A (ko) 2011-10-05
US20100189731A1 (en) 2010-07-29
EP3168307B1 (en) 2020-07-15
CA2744454A1 (en) 2010-06-03
RU2559527C2 (ru) 2015-08-10
EP2367566B2 (en) 2019-11-27
EP2367566B1 (en) 2016-10-05
WO2010063033A2 (en) 2010-06-03
IL213189A (en) 2015-10-29
US8394384B2 (en) 2013-03-12
GT201100145A (es) 2013-09-30
IL213189A0 (en) 2011-07-31
CN102271704A (zh) 2011-12-07

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Owner name: MERIAL, INC.