MC1528A1 - Imidazobenzodiazepines - Google Patents

Imidazobenzodiazepines

Info

Publication number: MC1528A1
Authority: MC; Monaco
Prior art keywords: lower alkyl; optionally substituted; propenylene; dimethylene; trimethylene
Prior art date: 1982-07-21

Application number

MC@@@@1648A

Other languages

English (en)

Inventor

Walter Hunkeler

Emilio Kyburz

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-07-21

Filing date

1983-06-19

Publication date

1984-04-13

1983-06-19 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1984-04-13 Publication of MC1528A1 publication Critical patent/MC1528A1/fr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
- C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Pyrrole Compounds (AREA)

MC@@@@1648A 1982-07-21 1983-06-19 Imidazobenzodiazepines MC1528A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH446082		1982-07-21

Publications (1)

Publication Number	Publication Date
MC1528A1 true MC1528A1 (fr)	1984-04-13

Family

ID=4276529

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MC@@@@1648A MC1528A1 (fr)	1982-07-21	1983-06-19	Imidazobenzodiazepines

Country Status (25)

Country	Link
US (1)	US4489003A (fr)
EP (1)	EP0100906B1 (fr)
JP (1)	JPS5933286A (fr)
KR (1)	KR840005836A (fr)
AT (1)	ATE27160T1 (fr)
AU (1)	AU560286B2 (fr)
BR (1)	BR8303898A (fr)
CA (1)	CA1202969A (fr)
CS (1)	CS246063B2 (fr)
CU (1)	CU21554A3 (fr)
DE (1)	DE3371516D1 (fr)
DK (1)	DK335083A (fr)
ES (4)	ES8500945A1 (fr)
FI (1)	FI832654A (fr)
GR (1)	GR79322B (fr)
HU (1)	HU189719B (fr)
IE (1)	IE56121B1 (fr)
IL (1)	IL69242A (fr)
MC (1)	MC1528A1 (fr)
NO (1)	NO832633L (fr)
NZ (1)	NZ204912A (fr)
PH (1)	PH18980A (fr)
PT (1)	PT77063B (fr)
ZA (1)	ZA835147B (fr)
ZW (1)	ZW14383A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3587913D1 (de) *	1984-01-19	1994-10-06	Hoffmann La Roche	Imidazodiazepin-Derivate.
CA1259612A (fr) *	1985-02-28	1989-09-19	Emilio Kyburz	Derives d'imidazodiazepine
DK174086D0 (da) *	1986-04-16	1986-04-16	Ferrosan As	Nye benzodiazepinderivater samt fremgangsmaade til fremstilling af samme
GB8720414D0 (en) *	1987-08-28	1987-10-07	Roussel Lab Ltd	Chemical compounds
CA2015336A1 (fr) *	1989-05-19	1990-11-19	F. Hoffmann-La Roche Ag	Imidazodiazepines pour le traitement des symptomes neurologiques
IE910939A1 (en) *	1990-04-13	1991-10-23	Neurosearch As	Use of benzodiazepine compounds
GB9911152D0 (en) *	1999-05-14	1999-07-14	Glaxo Group Ltd	Short-acting benzodiazepines
US7160880B1 (en)	1999-05-14	2007-01-09	Cenes Limited	Short-acting benzodiazepines
US7595395B2 (en) *	2005-05-16	2009-09-29	Wisys Technology Foundation	Gabaergic agents to treat memory deficits
DK2081921T3 (da)	2006-07-10	2011-01-03	Paion Uk Ltd	Korttidsvirkende benzodiazepinsalte og deres polymorfe former
BRPI0815579A2 (pt)	2007-08-20	2015-02-18	Evotec Neurosciences Gmbh	Tratamento de distúrbio do sono
US20090054412A1 (en) *	2007-08-20	2009-02-26	John Alan Kemp	Treatment of Sleep Disorders
EP2450039A1 (fr)	2010-11-08	2012-05-09	PAION UK Ltd.	Régime de dosage permettant la sédation avec CNS 7056 (Remimazolam)
AR094963A1 (es)	2013-03-04	2015-09-09	Ono Pharmaceutical Co	Reacción de oxidación excelente en el índice de conversión
WO2021113492A1 (fr) *	2019-12-06	2021-06-10	Schrödinger, Inc.	Composés cycliques et leurs procédés d'utilisation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1143728A (fr) *	1979-10-04	1983-03-29	Max Gerecke	Derives d'imidazodiazepine
US4352817A (en) *	1981-02-27	1982-10-05	Hoffmann-La Roche Inc.	Imidazo-diazepines and their use
CA1185602A (fr) *	1981-02-27	1985-04-16	Emilio Kyburz	Imidazodiazepines
CA1173441A (fr) *	1981-02-27	1984-08-28	Hoffmann-La Roche Limited	Imidazodiazepines
CA1184175A (fr) *	1981-02-27	1985-03-19	Walter Hunkeler	Imidazodiazepines

1983
- 1983-06-19 MC MC@@@@1648A patent/MC1528A1/fr unknown
- 1983-06-24 ZW ZW143/83A patent/ZW14383A1/xx unknown
- 1983-06-24 CA CA000431129A patent/CA1202969A/fr not_active Expired
- 1983-07-14 EP EP83106920A patent/EP0100906B1/fr not_active Expired
- 1983-07-14 AT AT83106920T patent/ATE27160T1/de not_active IP Right Cessation
- 1983-07-14 DE DE8383106920T patent/DE3371516D1/de not_active Expired
- 1983-07-14 US US06/513,571 patent/US4489003A/en not_active Expired - Fee Related
- 1983-07-14 ZA ZA835147A patent/ZA835147B/xx unknown
- 1983-07-15 AU AU16888/83A patent/AU560286B2/en not_active Ceased
- 1983-07-15 NZ NZ204912A patent/NZ204912A/en unknown
- 1983-07-15 IL IL69242A patent/IL69242A/xx unknown
- 1983-07-18 HU HU832533A patent/HU189719B/hu unknown
- 1983-07-19 CS CS835419A patent/CS246063B2/cs unknown
- 1983-07-19 KR KR1019830003325A patent/KR840005836A/ko not_active Application Discontinuation
- 1983-07-19 GR GR71965A patent/GR79322B/el unknown
- 1983-07-19 NO NO832633A patent/NO832633L/no unknown
- 1983-07-20 DK DK335083A patent/DK335083A/da not_active Application Discontinuation
- 1983-07-20 PH PH29251A patent/PH18980A/en unknown
- 1983-07-20 IE IE1696/83A patent/IE56121B1/xx unknown
- 1983-07-20 PT PT77063A patent/PT77063B/pt unknown
- 1983-07-20 ES ES524280A patent/ES8500945A1/es not_active Expired
- 1983-07-20 JP JP58131150A patent/JPS5933286A/ja active Pending
- 1983-07-20 BR BR8303898A patent/BR8303898A/pt unknown
- 1983-07-21 FI FI832654A patent/FI832654A/fi not_active Application Discontinuation
- 1983-07-21 CU CU8335935A patent/CU21554A3/es unknown
1984
- 1984-03-16 ES ES530671A patent/ES530671A0/es active Granted
- 1984-03-16 ES ES530672A patent/ES8505180A1/es not_active Expired
- 1984-03-16 ES ES530673A patent/ES8504805A1/es not_active Expired

Also Published As

Publication number	Publication date
ES524280A0 (es)	1984-11-16
CS541983A2 (en)	1985-12-16
EP0100906A2 (fr)	1984-02-22
ES530672A0 (es)	1985-05-16
ES8500945A1 (es)	1984-11-16
EP0100906B1 (fr)	1987-05-13
JPS5933286A (ja)	1984-02-23
AU560286B2 (en)	1987-04-02
CU21554A3 (en)	1987-06-09
ES530673A0 (es)	1985-05-01
DK335083A (da)	1984-01-22
GR79322B (fr)	1984-10-22
NO832633L (no)	1984-01-23
ES8505179A1 (es)	1985-05-16
EP0100906A3 (en)	1984-08-22
DE3371516D1 (de)	1987-06-19
DK335083D0 (da)	1983-07-20
ES8505180A1 (es)	1985-05-16
FI832654A0 (fi)	1983-07-21
NZ204912A (en)	1986-10-08
IL69242A (en)	1986-09-30
ZA835147B (en)	1984-03-28
HU189719B (en)	1986-07-28
AU1688883A (en)	1984-01-26
IE56121B1 (en)	1991-04-24
IE831696L (en)	1984-01-21
ZW14383A1 (en)	1985-01-23
PT77063B (en)	1986-07-15
CS246063B2 (en)	1986-10-16
BR8303898A (pt)	1984-04-10
PH18980A (en)	1985-11-29
IL69242A0 (en)	1983-11-30
ES8504805A1 (es)	1985-05-01
ATE27160T1 (de)	1987-05-15
FI832654A (fi)	1984-01-22
US4489003A (en)	1984-12-18
PT77063A (en)	1983-08-01
CA1202969A (fr)	1986-04-08
KR840005836A (ko)	1984-11-19
ES530671A0 (es)	1985-05-16

Publication	Publication Date	Title
FI832654A (fi)	1984-01-22	Imidazobenzodiazepiner
ES515904A0 (es)	1983-10-16	"procedimiento para preparar nuevas triazoloquinazolonas".
ES8101589A1 (es)	1980-12-16	Un procedimiento para la preparacion de nuevos compuestos iminicos heterociclicos.
DE3061396D1 (en)	1983-01-27	Oxazoline and thiazoline derivatives, processes for their preparation and pharmaceutical compositions containing them

Legal Events

Date	Code	Title	Description
1986-06-05	YP	Annual fee paid