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MA45709A - Composés diazahétérobicycliques substitués et leur utilisation - Google Patents

Composés diazahétérobicycliques substitués et leur utilisation

Info

Publication number
MA45709A
MA45709A MA045709A MA45709A MA45709A MA 45709 A MA45709 A MA 45709A MA 045709 A MA045709 A MA 045709A MA 45709 A MA45709 A MA 45709A MA 45709 A MA45709 A MA 45709A
Authority
MA
Morocco
Prior art keywords
diazaheterbicyclic
substituted
compounds
substituted diazaheterbicyclic
diazaheterbicyclic compounds
Prior art date
Application number
MA045709A
Other languages
English (en)
Inventor
Udo Albus
Johanna Anlahr
Moritz Beck-Broichsitter
Karl Collins
Martina Delbeck
Doris Gehring
Michael Hahn
Niels Lindner
Klemens Lustig
Thomas Müller
Janine Nicolai
Björn Rosenstein
Original Assignee
Bayer Ag
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Bayer Pharma AG filed Critical Bayer Ag
Publication of MA45709A publication Critical patent/MA45709A/fr

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/60—In silico combinatorial chemistry
    • G16C20/64—Screening of libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • G—PHYSICS
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    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
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    • C07B2200/07—Optical isomers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Reproductive Health (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Otolaryngology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Theoretical Computer Science (AREA)
MA045709A 2016-07-20 2017-07-10 Composés diazahétérobicycliques substitués et leur utilisation MA45709A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16180315 2016-07-20
EP16203964 2016-12-14

Publications (1)

Publication Number Publication Date
MA45709A true MA45709A (fr) 2019-05-29

Family

ID=59381270

Family Applications (1)

Application Number Title Priority Date Filing Date
MA045709A MA45709A (fr) 2016-07-20 2017-07-10 Composés diazahétérobicycliques substitués et leur utilisation

Country Status (21)

Country Link
US (2) US20210024545A1 (fr)
EP (1) EP3487856B1 (fr)
JP (3) JP6999639B2 (fr)
KR (1) KR102444687B1 (fr)
CN (2) CN109476665B (fr)
AU (2) AU2017298421B2 (fr)
BR (1) BR112019001141A2 (fr)
CA (1) CA3031136A1 (fr)
CL (1) CL2019000129A1 (fr)
IL (1) IL264258B (fr)
JO (1) JOP20190005A1 (fr)
MA (1) MA45709A (fr)
MX (1) MX2019000785A (fr)
PH (1) PH12019500131A1 (fr)
SG (1) SG11201900460RA (fr)
SV (1) SV2019005812A (fr)
TN (1) TN2020000021A1 (fr)
TW (1) TW201808293A (fr)
UA (1) UA125516C2 (fr)
UY (1) UY37328A (fr)
WO (1) WO2018015196A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201804449WA (en) 2015-12-10 2018-06-28 Bayer Pharma AG 2-phenyl-3-(piperazinomethyl)imidazo[1,2-a]pyridine derivatives as blockers of task-1 and task-2 channels, for the treatment of sleep-related breathing disorders
CA3007699A1 (fr) 2015-12-10 2017-06-15 Bayer Pharma Aktiengesellschaft Derives de perhydropyrrolo[3,4-c]pyrrole substitues et leur utilisation
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