MA43567A - Anticorps pacap et leurs utilisations - Google Patents
Anticorps pacap et leurs utilisationsInfo
- Publication number
- MA43567A MA43567A MA043567A MA43567A MA43567A MA 43567 A MA43567 A MA 43567A MA 043567 A MA043567 A MA 043567A MA 43567 A MA43567 A MA 43567A MA 43567 A MA43567 A MA 43567A
- Authority
- MA
- Morocco
- Prior art keywords
- pacap antibodies
- pacap
- antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562267822P | 2015-12-15 | 2015-12-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA43567A true MA43567A (fr) | 2018-11-14 |
Family
ID=57708866
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA043567A MA43567A (fr) | 2015-12-15 | 2016-12-15 | Anticorps pacap et leurs utilisations |
Country Status (4)
Country | Link |
---|---|
US (2) | US10822408B2 (fr) |
EP (1) | EP3390447A1 (fr) |
MA (1) | MA43567A (fr) |
WO (1) | WO2017106578A1 (fr) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2959480T3 (es) | 2014-02-07 | 2024-02-26 | Univ Mcmaster | Acoplador de células T - antígeno trifuncional y métodos y usos del mismo |
WO2016168757A1 (fr) | 2015-04-16 | 2016-10-20 | Alder Biopharmaceuticals, Inc. | Utilisation d'anticorps anti-pacap et de leurs fragments de liaison à l'antigène pour le traitement, la prévention ou l'inhibition de la photophobie |
MA43567A (fr) | 2015-12-15 | 2018-11-14 | Amgen Inc | Anticorps pacap et leurs utilisations |
CA3020839A1 (fr) | 2016-04-15 | 2017-10-19 | Alder Biopharmaceuticals, Inc. | Anticorps anti-pacap et leurs utilisations |
AR113022A1 (es) * | 2017-09-29 | 2020-01-15 | Lilly Co Eli | Anticuerpo anti-pacap |
CN111479925B (zh) | 2017-10-12 | 2024-03-08 | 麦克马斯特大学 | 具有y182t突变的t细胞-抗原偶联物及其方法和用途 |
AU2019207915A1 (en) | 2018-01-12 | 2020-07-16 | Amgen Inc. | PAC1 antibodies and uses thereof |
US11110123B2 (en) | 2018-07-17 | 2021-09-07 | Triumvira Immunologics Usa, Inc. | T cell-antigen coupler with various construct optimizations |
US10640562B2 (en) | 2018-07-17 | 2020-05-05 | Mcmaster University | T cell-antigen coupler with various construct optimizations |
MX2021015791A (es) | 2019-06-28 | 2022-04-01 | Amgen Inc | Proteínas de unión al antígeno biespecificas anti-receptor de cgrp/anti-receptor pac1. |
EP4093756A4 (fr) * | 2020-01-23 | 2024-06-12 | United Biomedical Inc. | Immunogènes peptidiques ciblant le peptide d'activation d'adénylate cyclase pituitaire (pacap) et formulations associées pour la prévention et le traitement de la migraine |
EP4347660A1 (fr) | 2021-06-01 | 2024-04-10 | Triumvira Immunologics USA, Inc. | Coupleurs d'antigène de lymphocytes t de claudine 18.2 et leurs utilisations |
US11453723B1 (en) | 2021-06-25 | 2022-09-27 | Mcmaster University | BCMA T cell-antigen couplers and uses thereof |
US20230212281A1 (en) * | 2021-07-29 | 2023-07-06 | Cephalon, LLC | Compositions and methods for anti-pacap antibodies |
CN118344476A (zh) * | 2024-05-16 | 2024-07-16 | 武汉爱博泰克生物科技有限公司 | 人c反应蛋白单克隆抗体、抗体对和检测试剂或试剂盒及其应用 |
Family Cites Families (66)
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US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
USRE30985E (en) | 1978-01-01 | 1982-06-29 | Serum-free cell culture media | |
US4560655A (en) | 1982-12-16 | 1985-12-24 | Immunex Corporation | Serum-free cell culture medium and process for making same |
US4657866A (en) | 1982-12-21 | 1987-04-14 | Sudhir Kumar | Serum-free, synthetic, completely chemically defined tissue culture media |
US4767704A (en) | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
GB8516415D0 (en) | 1985-06-28 | 1985-07-31 | Celltech Ltd | Culture of animal cells |
US4927762A (en) | 1986-04-01 | 1990-05-22 | Cell Enterprises, Inc. | Cell culture medium with antioxidant |
US4965195A (en) | 1987-10-26 | 1990-10-23 | Immunex Corp. | Interleukin-7 |
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GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
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US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
WO1991010741A1 (fr) | 1990-01-12 | 1991-07-25 | Cell Genesys, Inc. | Generation d'anticorps xenogeniques |
US6713610B1 (en) | 1990-01-12 | 2004-03-30 | Raju Kucherlapati | Human antibodies derived from immunized xenomice |
WO1996033735A1 (fr) | 1995-04-27 | 1996-10-31 | Abgenix, Inc. | Anticorps humains derives d'une xenosouris immunisee |
US6673986B1 (en) | 1990-01-12 | 2004-01-06 | Abgenix, Inc. | Generation of xenogeneic antibodies |
DE69132864T2 (de) | 1990-03-17 | 2002-08-08 | Takeda Chemical Industries, Ltd. | Antikörper gegen hypophysäre adenylatzyklase aktivierende peptid-pacap, hybridome und bestimmung von pacap |
WO1991018982A1 (fr) | 1990-06-05 | 1991-12-12 | Immunex Corporation | Recepteurs de l'interleukine-1 de type ii |
US6255458B1 (en) | 1990-08-29 | 2001-07-03 | Genpharm International | High affinity human antibodies and human antibodies against digoxin |
US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
US5874299A (en) | 1990-08-29 | 1999-02-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
US5877397A (en) | 1990-08-29 | 1999-03-02 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
US6300129B1 (en) | 1990-08-29 | 2001-10-09 | Genpharm International | Transgenic non-human animals for producing heterologous antibodies |
KR100272077B1 (ko) | 1990-08-29 | 2000-11-15 | 젠팜인터내셔날,인코포레이티드 | 이종 항체를 생산할 수 있는 전이유전자를 가진 인간이외의 동물 |
US5122469A (en) | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
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EP0618291A3 (fr) | 1993-02-26 | 1997-12-03 | Takeda Chemical Industries, Ltd. | Protéine réceptrice-PACAP, méthode pour la préparation de cette protéine et l'utilisation de celle-ci |
US6399316B1 (en) | 1994-02-25 | 2002-06-04 | Takeda Chemical Industries, Ltd. | PACAP receptor protein, method for preparing said protein, and use thereof |
US6130364A (en) | 1995-03-29 | 2000-10-10 | Abgenix, Inc. | Production of antibodies using Cre-mediated site-specific recombination |
US6096871A (en) | 1995-04-14 | 2000-08-01 | Genentech, Inc. | Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life |
US6462016B1 (en) | 1995-10-06 | 2002-10-08 | Shiseido Company, Ltd. | Method for screening agonist or antagonist of the maxadilan receptor participating in vasodilating action, and compound found by the method |
DE69731289D1 (de) | 1996-03-18 | 2004-11-25 | Univ Texas | Immunglobulinähnliche domäne mit erhöhten halbwertszeiten |
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EP1098906B1 (fr) | 1998-07-20 | 2009-11-25 | Ipsen Pharma | Analogues peptidiques des pacap |
US6242563B1 (en) | 1998-07-20 | 2001-06-05 | Societe De Conseils De Recherches Et D'applications Scientifiques, Sas | Peptide analogues |
US6660843B1 (en) | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
US20020155533A1 (en) | 1998-11-30 | 2002-10-24 | Takeda Chemical | PACAP receptor protein, method for preparing said protein, and use thereof |
US20020182729A1 (en) | 2001-01-11 | 2002-12-05 | Dicicco-Bloom Emanuel | Pituitary adenylate cyclase-activating polypeptide (PACAP) is an anti-mitogenic signal for selected neuronal precursors in vivo |
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US20040132101A1 (en) | 2002-09-27 | 2004-07-08 | Xencor | Optimized Fc variants and methods for their generation |
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WO2004062684A2 (fr) * | 2003-01-16 | 2004-07-29 | D. Collen Research Foundation Vzw Onderwijs En Navorsing Campus Gasthuisberg K.U. Leuven | Inhibition de la signalisation pacap dans la prevention et le traitement de la thrombocytopenie |
US20050129687A1 (en) | 2003-11-03 | 2005-06-16 | University Of Vermont And State Agricultural College | Use of inhibitors of PACAP receptor activity for treatment of overactive bladder and pelvic floor pain syndrome |
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EP2048162A4 (fr) | 2006-08-08 | 2010-12-01 | Univ Kyoto | Nouvel anticorps monoclonal et son utilisation |
CN101668771B (zh) | 2007-03-12 | 2013-08-21 | 艾斯巴技术,爱尔康生物医药研究装置有限责任公司 | 单链抗体的基于序列的工程改造和最优化 |
US8793074B2 (en) | 2007-06-21 | 2014-07-29 | Saint Louis University | Sequence covariance networks, methods and uses therefor |
RU2540150C2 (ru) | 2007-06-25 | 2015-02-10 | Эсбатек, Эн Элкон Биомедикал Рисёрч Юнит Ллк | Способы модификации антител и модифицированные антитела с улучшенными функциональными свойствами |
WO2009033489A2 (fr) | 2007-09-11 | 2009-03-19 | Glostrup Hospital | Traitement de la migraine et de céphalées par des inhibiteurs sélectifs de pac1 |
CN101434649B (zh) | 2008-12-12 | 2012-04-25 | 余榕捷 | 一种环七肽及其制备方法和应用 |
RU2012106820A (ru) | 2009-07-27 | 2013-09-10 | Трайджемина Инк. | Способы лечения боли |
US20130011401A1 (en) | 2009-12-22 | 2013-01-10 | Novartis Ag | Soluble proteins for use as therapeutics |
JP5972915B2 (ja) | 2011-03-16 | 2016-08-17 | アムジエン・インコーポレーテツド | Fc変異体 |
ES2721882T3 (es) | 2011-12-23 | 2019-08-06 | Pfizer | Regiones constantes de anticuerpo modificadas por ingeniería genética para conjugación específica de sitio y procedimientos y usos de las mismas |
BR112014028838A2 (pt) | 2012-05-21 | 2020-05-12 | Genentech Inc | Usos de um anticorpo, método para fazer um anticorpo e anticorpos |
US9580486B2 (en) | 2013-03-14 | 2017-02-28 | Amgen Inc. | Interleukin-2 muteins for the expansion of T-regulatory cells |
WO2016168757A1 (fr) | 2015-04-16 | 2016-10-20 | Alder Biopharmaceuticals, Inc. | Utilisation d'anticorps anti-pacap et de leurs fragments de liaison à l'antigène pour le traitement, la prévention ou l'inhibition de la photophobie |
MA43567A (fr) | 2015-12-15 | 2018-11-14 | Amgen Inc | Anticorps pacap et leurs utilisations |
-
2016
- 2016-12-15 MA MA043567A patent/MA43567A/fr unknown
- 2016-12-15 WO PCT/US2016/067054 patent/WO2017106578A1/fr active Application Filing
- 2016-12-15 US US16/063,152 patent/US10822408B2/en active Active
- 2016-12-15 EP EP16820534.2A patent/EP3390447A1/fr active Pending
-
2020
- 2020-09-24 US US17/031,674 patent/US11780914B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US20210095016A1 (en) | 2021-04-01 |
US20180362643A1 (en) | 2018-12-20 |
EP3390447A1 (fr) | 2018-10-24 |
WO2017106578A1 (fr) | 2017-06-22 |
US10822408B2 (en) | 2020-11-03 |
US11780914B2 (en) | 2023-10-10 |
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