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MA41120A - Compositions comprenant le 15-hepe et méthodes de traitement ou de prévention de la fibrose à l'aide de celles-ci - Google Patents

Compositions comprenant le 15-hepe et méthodes de traitement ou de prévention de la fibrose à l'aide de celles-ci

Info

Publication number
MA41120A
MA41120A MA041120A MA41120A MA41120A MA 41120 A MA41120 A MA 41120A MA 041120 A MA041120 A MA 041120A MA 41120 A MA41120 A MA 41120A MA 41120 A MA41120 A MA 41120A
Authority
MA
Morocco
Prior art keywords
hepe
treating
methods
compositions including
preventing fibrosis
Prior art date
Application number
MA041120A
Other languages
English (en)
Inventor
John Climax
Kevin Duffy
Jonathan Rowe
Original Assignee
Afimmune Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Afimmune Ltd filed Critical Afimmune Ltd
Publication of MA41120A publication Critical patent/MA41120A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MA041120A 2014-12-02 2015-12-01 Compositions comprenant le 15-hepe et méthodes de traitement ou de prévention de la fibrose à l'aide de celles-ci MA41120A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462086535P 2014-12-02 2014-12-02

Publications (1)

Publication Number Publication Date
MA41120A true MA41120A (fr) 2017-10-10

Family

ID=56092410

Family Applications (1)

Application Number Title Priority Date Filing Date
MA041120A MA41120A (fr) 2014-12-02 2015-12-01 Compositions comprenant le 15-hepe et méthodes de traitement ou de prévention de la fibrose à l'aide de celles-ci

Country Status (18)

Country Link
US (1) US10363235B2 (fr)
EP (2) EP3988101A1 (fr)
JP (2) JP6986445B2 (fr)
KR (1) KR20170102879A (fr)
CN (2) CN107206008A (fr)
AU (2) AU2015358512B2 (fr)
BR (1) BR112017011685A2 (fr)
CA (1) CA2968980A1 (fr)
ES (1) ES2900593T3 (fr)
HK (1) HK1245101A1 (fr)
IL (2) IL252431B (fr)
MA (1) MA41120A (fr)
MX (2) MX2017007000A (fr)
PH (1) PH12017501022A1 (fr)
RU (2) RU2721555C2 (fr)
SG (2) SG10202010594WA (fr)
WO (1) WO2016090030A1 (fr)
ZA (2) ZA201704463B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201301626D0 (en) 2013-01-30 2013-03-13 Dignity Sciences Ltd Composition comprising 15-OHEPA and methods of using the same
CN105899485B (zh) 2013-11-15 2018-10-19 尊严科学有限公司 多不饱和羟基脂肪酸的药学上可接受的盐
KR20160132372A (ko) * 2014-01-10 2016-11-18 디그너티 사이언스 리미티드 15-hepe를 포함하는 약제학적 조성물 및 이를 이용하는 천식 및 폐 장애의 치료 방법
EP3247348A1 (fr) * 2015-01-16 2017-11-29 Afimmune Limited Compositions à base de 15-hepe et leurs méthodes d'utilisation
MA47141A (fr) 2015-05-13 2019-11-06 Ds Biopharma Ltd Compositions comprenant du15-oxo-epa ou du 15-oxo-dgla et leurs procédés de préparation et d'utilisation
KR20230047501A (ko) 2015-12-18 2023-04-07 애피뮨 리미티드 15-hepe를 포함하는 조성물 및 이를 사용하는 방법
US20210315851A1 (en) 2020-04-03 2021-10-14 Afimmune Limited Compositions comprising 15-hepe and methods of treating or preventing hematologic disorders, and/or related diseases

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6180671B1 (en) * 1998-03-10 2001-01-30 Beth Israel Deaconess Medical Center, Inc. Methods for treating disorders in which docosahexaenoic acid (DHA) levels are affected
JP2000191525A (ja) 1998-12-25 2000-07-11 Nof Corp 皮膚外用剤組成物
AU2634101A (en) * 2000-01-06 2001-07-16 Martek Biosciences Corporation Therapeutic preparations of highly unsaturated fatty acids
MXPA02007915A (es) 2000-02-16 2005-06-20 Brigham & Womens Hospital Mediador de lipido activado por aspirina.
JP2005179211A (ja) 2003-12-17 2005-07-07 Idemitsu Kosan Co Ltd 皮膚外用剤組成物
EP1711173A2 (fr) 2003-12-31 2006-10-18 Igennus Limited Formulation contenant de l'acide eicosapentaenoique ou un ester de celui-ci et d'un triterpene ou un ester de celui-ci
US20050239889A1 (en) 2004-04-26 2005-10-27 Jean Gosselin In vivo release of endogenous anti-microbial mediators by leukotriene B4 (LTB4) administration
CN101523221A (zh) * 2006-08-08 2009-09-02 利普米克斯科技公司 非酒精性脂肪肝病(nafld)和非酒精性脂肪性肝炎(nash)的标记及其使用方法
US8042070B2 (en) * 2007-10-23 2011-10-18 International Business Machines Corporation Methods and system for analysis and management of parametric yield
GB0802116D0 (en) * 2008-02-05 2008-03-12 Natural Enviromental Res Counc Treatment
PE20100156A1 (es) * 2008-06-03 2010-02-23 Boehringer Ingelheim Int Tratamiento de nafld
WO2009154230A1 (fr) 2008-06-17 2009-12-23 持田製薬株式会社 Agent de prévention/amélioration ou de traitement de la stéatose hépatique non alcoolique
WO2010120880A1 (fr) * 2009-04-14 2010-10-21 Vertex Pharmaceuticals Incorporated Traitement de maladies hépatiques avec un inhibiteur de caspase
GB0907413D0 (en) 2009-04-29 2009-06-10 Equateq Ltd Novel methods
US10154977B2 (en) * 2011-03-25 2018-12-18 The Brigham And Women's Hospital, Inc. Anti-inflammatory particles
US20120264824A1 (en) * 2011-04-15 2012-10-18 Mochida Pharmaceutical Co., Ltd. Compositions and methods for treating non-alcoholic steatohepatitis
JP6185473B2 (ja) * 2011-09-16 2017-08-23 ガレクティン・セラピューティクス・インコーポレイテッドGalectin Therapeutics, Inc. 非アルコール性脂肪性肝炎および非アルコール性脂肪肝疾患を処置するためのガラクト−ラムノガラクツロネート組成物
WO2013057287A1 (fr) 2011-10-19 2013-04-25 Dignity Sciences Limited Compositions pharmaceutiques comprenant dgla, 15-ohepa, et/ou 15-hetre et leurs procédés d'utilisation
US8293790B2 (en) 2011-10-19 2012-10-23 Dignity Sciences Limited Pharmaceutical compositions comprising DGLA and benzoyl peroxide and methods of use thereof
KR20140113921A (ko) 2011-11-29 2014-09-25 디그너티 사이언스 리미티드 20-탄소 지방산을 포함하는 조성물 및 이를 제조 및 사용하는 방법
JP2015504870A (ja) * 2011-12-16 2015-02-16 タリックス ファーマシューティカルズ リミテッド 線維症を処置するためのアンジオテンシン
US20120264705A1 (en) 2012-01-26 2012-10-18 Dignity Sciences Limited Antimicrobial compositions comprising 15-hetre and methods of use thereof
US20130267598A1 (en) 2012-02-23 2013-10-10 Dignity Sciences Limited Pharmaceutical compositions comprising dgla, 15-ohepa, and/or 15-hetre and methods of reducing sebum production using same
PL2858496T3 (pl) 2012-05-10 2023-09-11 Solutex Na Llc Oleje o działaniu przeciwzapalnym zawierające naturalne wyspecjalizowane mediatory prorozdzielcze i ich prekursory
GB201301626D0 (en) 2013-01-30 2013-03-13 Dignity Sciences Ltd Composition comprising 15-OHEPA and methods of using the same
TWI742541B (zh) * 2013-03-15 2021-10-11 英商邊緣生物科技有限公司 用於治療肺纖維化、肝纖維化、皮膚纖維化及心臟纖維化之經取代之芳族化合物
KR20230047501A (ko) 2015-12-18 2023-04-07 애피뮨 리미티드 15-hepe를 포함하는 조성물 및 이를 사용하는 방법

Also Published As

Publication number Publication date
US10363235B2 (en) 2019-07-30
ZA201804380B (en) 2021-03-31
BR112017011685A2 (pt) 2018-01-02
RU2017122758A (ru) 2019-01-09
EP3988101A1 (fr) 2022-04-27
KR20170102879A (ko) 2017-09-12
SG11201704495VA (en) 2017-06-29
CN107206008A (zh) 2017-09-26
JP6986445B2 (ja) 2021-12-22
EP3226873A1 (fr) 2017-10-11
HK1245101A1 (zh) 2018-08-24
RU2020115523A (ru) 2021-01-27
SG10202010594WA (en) 2020-12-30
EP3226873A4 (fr) 2018-08-08
IL252431A0 (en) 2017-07-31
JP2017536380A (ja) 2017-12-07
EP3226873B1 (fr) 2021-10-27
AU2015358512A1 (en) 2017-07-20
AU2021203189A1 (en) 2021-06-10
US20160184252A1 (en) 2016-06-30
PH12017501022B1 (en) 2017-11-27
PH12017501022A1 (en) 2017-11-27
MX2021005080A (es) 2021-06-15
CA2968980A1 (fr) 2016-06-09
ES2900593T3 (es) 2022-03-17
RU2017122758A3 (fr) 2019-06-13
RU2721555C2 (ru) 2020-05-20
MX2017007000A (es) 2017-12-07
CN112245419A (zh) 2021-01-22
WO2016090030A1 (fr) 2016-06-09
IL287983A (en) 2022-01-01
ZA201704463B (en) 2018-11-28
IL252431B (en) 2021-12-01
AU2015358512B2 (en) 2021-02-18
JP2022031813A (ja) 2022-02-22

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