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Han et al., 2019 - Google Patents

Redox-sensitive micelles for targeted intracellular delivery and combination chemotherapy of paclitaxel and all-trans-retinoid acid

Han et al., 2019

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Document ID
3991818698786239428
Author
Han L
Hu L
Liu F
Wang X
Huang X
Liu B
Feng F
Liu W
Qu W
Publication year
Publication venue
Asian Journal of Pharmaceutical Sciences

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The application of paclitaxel (PTX) in clinic has been restricted due to its poor solubility. Several traditional nano-medicines have been developed to improve this defect, while they are still lack of tumor targeting ability and rapid drug release. In this work, an amphiphilic …
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    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
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