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Bronson, 2005 - Google Patents

Ezetimibe plus simvastatin lowered lipid levels more than simvastatin monotherapy in primary hypercholesterolemia

Bronson, 2005

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Document ID
3765156448034947292
Author
Bronson D
Publication year
Publication venue
ACP Journal Club

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Snippet

Setting: 31 sites in the United States and 40 sites in 22 other countries. Patients: 887 patients≥ 18 years of age (mean age 56 y, age range 22 to 81 y, 53% women) with primary hypercholesterolemia (low-density lipoprotein cholesterol [LDL-C] 145 to 250 mg/dL [3.76 to …
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]

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