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Munch et al., 2016 - Google Patents

Extension of helix 12 in Munc18-1 induces vesicle priming

Munch et al., 2016

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Document ID
3710794138550383350
Author
Munch A
Kedar G
van Weering J
Vazquez-Sanchez S
He E
André T
Braun T
Söllner T
Verhage M
Sørensen J
Publication year
Publication venue
Journal of Neuroscience

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Snippet

Munc18-1 is essential for vesicle fusion and participates in the docking of large dense-core vesicles to the plasma membrane. Recent structural data suggest that conformational changes in the 12th helix of the Munc18-1 domain 3a within the Munc18-1: syntaxin …
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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