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Bhargava et al., 2011 - Google Patents

Development of second-generation VEGFR tyrosine kinase inhibitors: current status

Bhargava et al., 2011

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Document ID
3620077799077386908
Author
Bhargava P
Robinson M
Publication year
Publication venue
Current oncology reports

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The vascular endothelial growth factor (VEGF) signaling pathway appears to be the dominant pathway involved in tumor angiogenesis, providing a rationale for targeting the VEGF receptors (VEGFR-1,-2, and-3) in the treatment of cancers. In particular, VEGF …
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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