Nothing Special   »   [go: up one dir, main page]

Mehle et al., 2009 - Google Patents

Adaptive strategies of the influenza virus polymerase for replication in humans

Mehle et al., 2009

View HTML @Full View
Document ID
3202702365702590306
Author
Mehle A
Doudna J
Publication year
Publication venue
Proceedings of the National Academy of Sciences

External Links

Snippet

Transmission of influenza viruses into the human population requires surmounting barriers to cross-species infection. Changes in the influenza polymerase overcome one such barrier. Viruses isolated from birds generally contain polymerases with the avian-signature glutamic …
Continue reading at www.pnas.org (HTML) (other versions)

Classifications

    • GPHYSICS
    • G06COMPUTING; CALCULATING; COUNTING
    • G06QDATA PROCESSING SYSTEMS OR METHODS, SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL, SUPERVISORY OR FORECASTING PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL, SUPERVISORY OR FORECASTING PURPOSES, NOT OTHERWISE PROVIDED FOR
    • G06Q30/00Commerce, e.g. shopping or e-commerce
    • G06Q30/02Marketing, e.g. market research and analysis, surveying, promotions, advertising, buyer profiling, customer management or rewards; Price estimation or determination
    • G06Q30/0241Advertisement
    • G06Q30/0251Targeted advertisement

Similar Documents

Publication Publication Date Title
Mehle et al. Adaptive strategies of the influenza virus polymerase for replication in humans
Jackson et al. A new influenza virus virulence determinant: the NS1 protein four C-terminal residues modulate pathogenicity
Tong et al. A distinct lineage of influenza A virus from bats
Sun et al. High genetic compatibility and increased pathogenicity of reassortants derived from avian H9N2 and pandemic H1N1/2009 influenza viruses
Muratore et al. Small molecule inhibitors of influenza A and B viruses that act by disrupting subunit interactions of the viral polymerase
Li et al. Reassortment between avian H5N1 and human H3N2 influenza viruses creates hybrid viruses with substantial virulence
Gavazzi et al. A functional sequence-specific interaction between influenza A virus genomic RNA segments
Liu et al. Cross-species recognition of SARS-CoV-2 to bat ACE2
Russier et al. Molecular requirements for a pandemic influenza virus: an acid-stable hemagglutinin protein
Aldridge Jr et al. TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection
Langlois et al. Hematopoietic-specific targeting of influenza A virus reveals replication requirements for induction of antiviral immune responses
Das et al. Structural basis for suppression of a host antiviral response by influenza A virus
Yang et al. Prevalence, genetics, and transmissibility in ferrets of Eurasian avian-like H1N1 swine influenza viruses
Jagger et al. An overlapping protein-coding region in influenza A virus segment 3 modulates the host response
Rivas et al. Shutoff of host gene expression in influenza A virus and herpesviruses: similar mechanisms and common themes
Walsh et al. Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus
Min et al. The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: Inhibiting the 2′-5′ oligo (A) synthetase/RNase L pathway
Pappas et al. Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus
Guan et al. H5N1 influenza: a protean pandemic threat
Graef et al. The PB2 subunit of the influenza virus RNA polymerase affects virulence by interacting with the mitochondrial antiviral signaling protein and inhibiting expression of beta interferon
Worobey et al. Genesis and pathogenesis of the 1918 pandemic H1N1 influenza A virus
Kimble et al. Compatibility of H9N2 avian influenza surface genes and 2009 pandemic H1N1 internal genes for transmission in the ferret model
Mehle et al. Reassortment and mutation of the avian influenza virus polymerase PA subunit overcome species barriers
Hale et al. Influenza A virus NS1 protein binds p85β and activates phosphatidylinositol-3-kinase signaling
Tumpey et al. Existing antivirals are effective against influenza viruses with genes from the 1918 pandemic virus