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Friedland et al., 2013 - Google Patents

Heritable genome editing in C. elegans via a CRISPR-Cas9 system

Friedland et al., 2013

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Document ID
2995388012596763707
Author
Friedland A
Tzur Y
Esvelt K
Colaiácovo M
Church G
Calarco J
Publication year
Publication venue
Nature methods

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Snippet

We report the use of clustered, regularly interspaced, short palindromic repeats (CRISPR)- associated endonuclease Cas9 to target genomic sequences in the Caenorhabditis elegans germ line using single-guide RNAs that are expressed from a U6 small nuclear RNA …
Continue reading at pmc.ncbi.nlm.nih.gov (PDF) (other versions)

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